COLLAGEN PEPTIDE-BASED MEDICAMENT COMPOSITIONS AND DEVICES AND METHODS OF PRODUCTION AND USE THEREOF

    公开(公告)号:US20230048200A1

    公开(公告)日:2023-02-16

    申请号:US17854986

    申请日:2022-06-30

    IPC分类号: A61K38/39 A61P27/02 A61K9/00

    摘要: The present invention is in the fields of medicinal chemistry, biotechnology and pharmaceuticals. The invention provides compositions comprising one or more collagen mimetic peptides, optionally attached to one or more therapeutic compounds or one or more imaging compounds, for use in methods of treating, preventing, ameliorating, curing and diagnosing certain diseases and physical disorders in humans and veterinary animals, particularly anterior and posterior segment ocular diseases and physical disorders, paraocular and extraocular diseases and physical disorders, and nerve or nervous system diseases and physical disorders, as well as methods of manufacturing such compositions. The invention also provides medical devices comprising one or more such compositions of the invention. The invention also provides methods of use of such compositions and devices in treating and diagnosing certain diseases and physical disorders in humans and veterinary animals, including anterior and posterior segment ocular diseases or disorders, paraocular and extraocular diseases and physical disorders, and nerve or nervous system diseases or disorders.

    COLLAGEN PEPTIDE-BASED MEDICAMENT COMPOSITIONS AND USES THEREOF

    公开(公告)号:US20240016900A1

    公开(公告)日:2024-01-18

    申请号:US18342492

    申请日:2023-06-27

    IPC分类号: A61K38/39 A61P27/10 A61K47/64

    摘要: The present invention is in the fields of medicinal chemistry, biotechnology and pharmaceuticals. The invention provides compositions comprising one or more collagen mimetic peptides, optionally attached to one or more therapeutic compounds or one or more imaging compounds, methods for use of such compositions in treating, preventing, ameliorating, curing and/or diagnosing certain diseases and physical disorders in humans and veterinary animals, including anterior segment ocular diseases and physical disorders, including corneoscleral diseases, disorders or conditions such as myopia, presbyopia, keratoconus and the like. The invention also provides the use of such compositions in treating, preventing, ameliorating, curing and/or diagnosing diseases, disorders and conditions in a variety of other tissues, organs and organ systems. The invention also provides methods of manufacturing such collagen mimetic peptides and compositions. The invention also provides medical devices comprising one or more such compositions of the invention.