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公开(公告)号：US20240269191A1
公开(公告)日：2024-08-15
申请号：US18569991
申请日：2022-02-01
申请人： PANAGY CO., LTD.
发明人： Shoji KOGA
摘要： An ocular symptom-improving agent which is a composition containing a culture supernatant of dental pulp-derived stem cells or immortalized stem cells thereof and which is used for improving a symptom of myopia, astigmatism, presbyopia, eye fatigue or blurred vision is a novel ocular symptom-improving agent.
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公开(公告)号：US20240165089A1
公开(公告)日：2024-05-23
申请号：US18418181
申请日：2024-01-19
发明人： Xiangtian Zhou , Sen Zhang , Jia Qu , Qinyuan Zheng
IPC分类号： A61K31/4375 , A61K9/00 , A61K47/38 , A61P27/10
CPC分类号： A61K31/4375 , A61K9/0048 , A61K47/38 , A61P27/10
摘要： The present application relates to a method for treating myopia with vipocetine, which can effectively prevent myopia and/or control the progression of myopia while being safe and free of obvious side effects, having good prospects for clinical application.
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公开(公告)号：US20240103298A1
公开(公告)日：2024-03-28
申请号：US18012983
申请日：2021-12-27
发明人： Yi-Fang HUANG , Shih-Siang LIN
CPC分类号： G02C7/049 , A61P27/10 , G02C7/10 , G02C2202/24
摘要： An optical lens includes an optical zone, and the optical zone includes a relax zone, a distance zone, and a defocus zone. The distance zone surrounds the relax zone. The defocus zone surrounds the distance zone and the relax zone. The diopter of the relax zone reduces along a direction from a center of the optical zone to an edge of the optical zone.
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公开(公告)号：US20230414573A1
公开(公告)日：2023-12-28
申请号：US18036666
申请日：2021-11-11
IPC分类号： A61K31/4178 , A61K9/00 , A61K31/4174 , A61K31/498 , A61K31/728 , A61K31/196 , A61K45/06 , A61P27/10
CPC分类号： A61K31/4178 , A61K9/0048 , A61K31/4174 , A61P27/10 , A61K31/728 , A61K31/196 , A61K45/06 , A61K31/498
摘要： An ophthalmic composition for the prevention, control and treatment of presbyopia symptoms comprising a synergistic combination of pilocarpine, brimonidine, oxymetazoline, hyaluronic acid, bromfenac and optionally a vasoconstrictor in a single low concentration dose to improve near vision ability and increase depth of focus is described. In addition, the side effects of pilocarpine administered separately, such as eye redness, headache, and dryness of the eye, are reduced and are better tolerated in patients suffering from presbyopia.
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公开(公告)号：US20230414494A1
公开(公告)日：2023-12-28
申请号：US18465918
申请日：2023-09-12
发明人： Gerald HORN
IPC分类号： A61K9/00 , A61K9/08 , A61K47/02 , A61K47/26 , A61K47/38 , A61K31/439 , A61P27/10 , A61K31/4409 , A61K47/32 , A61K45/06 , A61K47/10 , A61K47/34
CPC分类号： A61K9/0048 , A61K9/08 , A61K47/02 , A61K47/26 , A61K47/38 , A61K31/439 , A61P27/10 , A61K31/4409 , A61K47/32 , A61K45/06 , A61K47/10 , A61K47/34
摘要： Provided herein is an ophthalmological composition and methods for the treatment of presbyopia. In some embodiments, the ophthalmological composition comprises aceclidine and brimonidine.
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公开(公告)号：US20230241042A1
公开(公告)日：2023-08-03
申请号：US18131963
申请日：2023-04-07
发明人： Ling HUANG , Xiaohua ZHANG , Mo ZHU , Wendian XIANG , Chao LIU , Jing KANG
IPC分类号： A61K31/439 , A61K9/00 , A61P27/10 , A61P27/02
CPC分类号： A61K31/439 , A61K9/0048 , A61P27/10 , A61P27/02
摘要： Provided is a use of a compound represented by Formula (I) or a nitrogen oxide, solvate, metabolite, pharmaceutically acceptable salt, or prodrug thereof in the preparation of medicament.
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公开(公告)号：US11648247B1
公开(公告)日：2023-05-16
申请号：US17552654
申请日：2021-12-16
发明人： Gerald Horn
IPC分类号： A61K31/498 , A61K31/439 , A61P27/10 , A61K47/10 , A61K47/36 , A61K47/02 , A61K47/40
CPC分类号： A61K31/498 , A61K31/439 , A61K47/02 , A61K47/10 , A61K47/36 , A61K47/40 , A61P27/10
摘要： The present invention is directed to compositions for and methods for the treatment of presbyopia comprising from about 0.3% to about 2.0% w/v aceclidine and from about 0.07% to about 0.15% w/v brimonidine.
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公开(公告)号：US11642350B2
公开(公告)日：2023-05-09
申请号：US16495350
申请日：2018-03-22
发明人： Tiang Hwee Donald Tan , Roger Wilmer Beuerman , Seang-Mei Saw , Aradhana Upadhyay , Masatomo Kato , Takaaki Inaba
IPC分类号： A61K31/5386 , A61P27/10 , A61K9/00
CPC分类号： A61K31/5386 , A61K9/0048 , A61P27/10
摘要： The present invention relates to an agent for preventing myopia, treating myopia, and/or preventing myopia progression, comprising tiotropium as an active ingredient.
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公开(公告)号：US20180177587A1
公开(公告)日：2018-06-28
申请号：US15580976
申请日：2016-06-13
CPC分类号： A61F2/145 , A61F2/142 , A61F2/148 , A61F9/0017 , A61F9/00736 , A61F9/00812 , A61F9/00834 , A61F9/013 , A61F2009/00872 , A61F2210/0085 , A61L27/18 , A61L27/20 , A61L27/24 , A61L27/52 , A61L2400/06 , A61L2430/16 , A61P27/10 , C08L5/08 , C08L89/06 , C08L83/04
摘要： A method for treating hyperopia or presbyopia in a patient, the method comprising making a cut deep in the patient's cornea to create a two-dimensional slit adjacent to and generally parallel to an anterior surface of the cornea and injecting a liquid or semi-solid transparent filler material into the deep cut in an amount sufficient to flatten the posterior surface of the cornea to increase the refractive power of the cornea by a predetermined correction of up to about 5 diopters due to the physical flattening of the posterior surface of the cornea, wherein the transparent filler material comprises a refractive index of about 1.3 to about 1.6, and forms a corneal implant with a lenticular shape within the cornea.
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公开(公告)号：US20240358544A1
公开(公告)日：2024-10-31
申请号：US18647758
申请日：2024-04-26
发明人： Brian STREM , Stefan SPERL , Eric DANIELS
CPC分类号： A61F9/0017 , A61P27/10
摘要： The present disclosure provides a method of treating a human subject suffering from a retinal disorder, the method comprising administering to the eye of the subject via intravitreal injection a composition comprising a compound of formula (I) as described herein.
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