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公开(公告)号：US08247606B2
公开(公告)日：2012-08-21
申请号：US13309643
申请日：2011-12-02
Applicant: Ganapathy Panchapakesan , Nagappan Arumugam , Pandi Suresh Pandian , Gollapalli Venkateswara Rao , Subramaniam Ganesan
Inventor： Ganapathy Panchapakesan , Nagappan Arumugam , Pandi Suresh Pandian , Gollapalli Venkateswara Rao , Subramaniam Ganesan
IPC: C07C319/28 , C07C319/14 , C07C233/46
CPC classification number: C07C231/12 , C07B2200/09 , C07C319/14 , C07C2601/02 , C07C233/63 , C07C323/58
Abstract: An improved process for preparing Cilastatin Sodium including dissolving Cilastatin acid in a solvent using an organic base, adding sodium salt of a week acid and isolating Cilastatin Sodium.
Abstract translation: 一种用于制备西司他丁钠的改进方法，包括使用有机碱溶解于溶剂中的西司他丁酸，加入一周酸的钠盐并分离西司他丁钠。
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公开(公告)号：US08293894B2
公开(公告)日：2012-10-23
申请号：US12312649
申请日：2007-11-20
Applicant: Andrew Gnanaprakasam , Nagappan Arumugam , Palanisamy Senthilkumar Udayampalayam , Pandi Suresh Pandian , Venugopal Sivasankaran , Ganapathy Veeramani , Henry Syril Sudhan , Gollapalli Venkateswara Rao
Inventor： Andrew Gnanaprakasam , Nagappan Arumugam , Palanisamy Senthilkumar Udayampalayam , Pandi Suresh Pandian , Venugopal Sivasankaran , Ganapathy Veeramani , Henry Syril Sudhan , Gollapalli Venkateswara Rao
IPC: C07D477/20
CPC classification number: C07D477/20 , Y02P20/55
Abstract: A process for the preparation of a carbapenem of formula (I): in amorphous form wherein R represents hydrogen or COOM and M represents hydrogen or sodium the process including condensing a compound of formula (II): wherein P′ denotes a carboxy protecting group, with a compound of formula (III): wherein P″ denotes a carboxy protecting group, in the presence of a base to yield a compound of formula (IV): deprotecting both the protecting groups in the compound of formula (IV) in the presence or absence of a sodium ion source, a solvent and in the presence or absence of CO2, gas, extracting the product into an aqueous medium, quenching the aqueous layer of into an alcohol at a temperature, and isolating the carbapenem compound of formula (I) in amorphous form.
Abstract translation: 制备式（I）的碳青霉烯的方法：无定形形式，其中R表示氢或COOM，M表示氢或钠，包括使式（II）化合物缩合的方法：其中P'表示羧基保护基， 与式（III）的化合物反应：其中P“表示羧基保护基，在碱存在下，得到式（IV）化合物：在存在下使式（IV）化合物中的保护基脱保护 或不存在钠离子源，溶剂，并且在存在或不存在CO 2的气体的情况下，将产物萃取到水性介质中，在一定温度下将水层猝灭为醇，并分离出式（I）的碳青霉烯化合物 ）。
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公开(公告)号：US20120078009A1
公开(公告)日：2012-03-29
申请号：US13309643
申请日：2011-12-02
Applicant: Ganapathy PANCHAPAKESAN , Nagappan ARUMUGAM , Pandi Suresh PANDIAN , Gollapalli Venkateswara RAO , Subramaniam GANESAN
Inventor： Ganapathy PANCHAPAKESAN , Nagappan ARUMUGAM , Pandi Suresh PANDIAN , Gollapalli Venkateswara RAO , Subramaniam GANESAN
IPC: C07C319/28 , C07C323/59
CPC classification number: C07C231/12 , C07B2200/09 , C07C319/14 , C07C2601/02 , C07C233/63 , C07C323/58
Abstract: An improved process for preparing Cilastatin Sodium including dissolving Cilastatin acid in a solvent using an organic base, adding sodium salt of a week acid and isolating Cilastatin Sodium.
Abstract translation: 一种用于制备西司他丁钠的改进方法，包括使用有机碱溶解于溶剂中的西司他丁酸，加入一周酸的钠盐并分离西司他丁钠。
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公开(公告)号：US20090143614A1
公开(公告)日：2009-06-04
申请号：US12084760
申请日：2006-11-03
Applicant: Ganapathy Panchapakesan , Nagappan Arumugam , Pandi Suresh Pandian , Gollapalli Venkateswara Rao , Subramaniam Ganesan
Inventor： Ganapathy Panchapakesan , Nagappan Arumugam , Pandi Suresh Pandian , Gollapalli Venkateswara Rao , Subramaniam Ganesan
IPC: C07C57/13
CPC classification number: C07C231/12 , C07B2200/09 , C07C319/14 , C07C2601/02 , C07C233/63 , C07C323/58
Abstract: The present invention relates to an improved process for the preparation of Cilastatin Sodium of formula (I). The present invention also provides an isolation technique for Cilastatin acid from the reaction mixture.
Abstract translation: 本发明涉及制备式（I）的西司他丁钠的改进方法。 本发明还提供了来自反应混合物的西司他丁酸的分离技术。
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Patent Agency Ranking
5.发明申请Document management system with enhanced intelligent document recognition capabilities 审中-公开文件管理系统具有增强的智能文档识别能力公开(公告)号：US20050289182A1
公开(公告)日：2005-12-29
申请号：US10894338
申请日：2004-07-20
Applicant: Suresh Pandian , Thyagarajan Swaminathan , Subramaniyan Neelagandan , Krishna Srinivasan , Randal Martin
Inventor： Suresh Pandian , Thyagarajan Swaminathan , Subramaniyan Neelagandan , Krishna Srinivasan , Randal Martin
CPC classification number: G06K9/00442 , G06Q10/10
Abstract: An intelligent document recognition-based document management system includes modules for image capture, image enhancement, image identification, optical character recognition, data extraction and quality assurance. The system captures data from electronic documents as diverse as facsimile images, scanned images and images from document management systems. It processes these images and presents the data in, for example, a standard XML format. The document management system processes both structured document images (ones which have a standard format) and unstructured document images (ones which do not have a standard format). The system can extract images directly from a facsimile machine, a scanner or a document management system for processing.
Abstract translation: 基于智能文档识别的文档管理系统包括用于图像捕获，图像增强，图像识别，光学字符识别，数据提取和质量保证的模块。 系统从电子文档中获取数据，如文件管理系统中的传真图像，扫描图像和图像。 它处理这些图像并将数据呈现在例如标准XML格式中。 文档管理系统处理结构化文档图像（具有标准格式的图像）和非结构化文档图像（不具有标准格式的图像）。 系统可以直接从传真机，扫描仪或文件管理系统中提取图像进行处理。
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6.发明申请Document/form processing method and apparatus using active documents and mobilized software 审中-公开使用活动文件和动员软件的文件/表格处理方法和装置公开(公告)号：US20050004885A1
公开(公告)日：2005-01-06
申请号：US10837889
申请日：2004-05-04
Applicant: Suresh Pandian , Thyagarajan Swaminathan , Johnson Pushpanathan , Krishna Srinivasan , Randal Martin
Inventor： Suresh Pandian , Thyagarajan Swaminathan , Johnson Pushpanathan , Krishna Srinivasan , Randal Martin
IPC: G06F7/00
CPC classification number: G06F16/25
Abstract: A server embeds typically static documents with program code enabling, for example, a form to intelligently route itself to a desired destination, to prompt a user to respond to particular questions, to perform validation operations, and to present various pull down list choices from which a user may select. Such an “active document” preferably has the capability of presenting a questionnaire to a user and to consolidate responses to the questionnaire. The active document-based questionnaire may be designed such that different questions are automatically sent to different recipients. A wide variety of applications are described including product sales lead generation and product marketing to enable the collection and optimal distribution of information regarding potential customer names, feedback concerning opinions about the product.
Abstract translation: 服务器通常将具有程序代码的静态文档嵌入到例如使得能够智能地将自身路由到期望目的地的窗体，以提示用户响应特定问题，执行验证操作以及呈现各种下拉列表选项， 用户可以选择。 这样的“活动文件”优选地具有向用户呈现问卷并且对问卷进行合并的能力。 可以设计基于活动的基于文档的问卷，使得不同的问题被自动发送到不同的接收者。 描述了各种各样的应用程序，包括产品销售线索生成和产品营销，以便收集和优化分发有关潜在客户名称的信息，以及有关产品意见的反馈。
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公开(公告)号：US20120253066A1
公开(公告)日：2012-10-04
申请号：US13512243
申请日：2010-12-16
Applicant: Khadangale Bhausaheb Pandharinath , Kahandal Bhimraj Suryabhan , Suresh Pandian Pandi , Senthilkumar Udayampalayam Palanisamy , Sureshkumar Kanagaraj , Pandiarajan Sivasubramanian
Inventor： Khadangale Bhausaheb Pandharinath , Kahandal Bhimraj Suryabhan , Suresh Pandian Pandi , Senthilkumar Udayampalayam Palanisamy , Sureshkumar Kanagaraj , Pandiarajan Sivasubramanian
IPC: C07C61/35
CPC classification number: C07B63/04 , A61K31/197 , C07C323/59 , C07C2601/02
Abstract: The present invention relates to an improved process for the preparation of Cilastatin Sodium of formula (I), having mesityl oxide content less than 2000 ppm and more than 1 ppm. (Formula I) (I)
Abstract translation: 本发明涉及制备式（I）的西司他丁钠的改进方法，其具有小于2000ppm且大于1ppm的平均氧化物含量。 （式I）（I）
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公开(公告)号：US08134026B2
公开(公告)日：2012-03-13
申请号：US12084760
申请日：2006-11-03
Applicant: Ganapathy Panchapakesan , Nagappan Arumugam , Pandi Suresh Pandian , Gollapalli Venkateswara Rao , Subramaniam Ganesan
Inventor： Ganapathy Panchapakesan , Nagappan Arumugam , Pandi Suresh Pandian , Gollapalli Venkateswara Rao , Subramaniam Ganesan
IPC: C07C319/28 , C07C319/14 , C07C233/46
CPC classification number: C07C231/12 , C07B2200/09 , C07C319/14 , C07C2601/02 , C07C233/63 , C07C323/58
Abstract: The present invention relates to an improved process for the preparation of Cilastatin Sodium of formula (I). The present invention also provides an isolation technique for Cilastatin acid from the reaction mixture.
Abstract translation: 本发明涉及制备式（I）的西司他丁钠的改进方法。 本发明还提供了来自反应混合物的西司他丁酸的分离技术。
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公开(公告)号：US20090312539A1
公开(公告)日：2009-12-17
申请号：US12312649
申请日：2007-11-20
Applicant: Andrew Gnanaprakasam , Nagappan Arumugam , Palanisamy Senthilkumar Udayampalayam , Pandi Suresh Pandian , Venugopal Sivasankaran , Ganapathy Veeramani , Henry Syril Sudhan , Gollapalli Venkateswara Rao
Inventor： Andrew Gnanaprakasam , Nagappan Arumugam , Palanisamy Senthilkumar Udayampalayam , Pandi Suresh Pandian , Venugopal Sivasankaran , Ganapathy Veeramani , Henry Syril Sudhan , Gollapalli Venkateswara Rao
IPC: C07D487/04
CPC classification number: C07D477/20 , Y02P20/55
Abstract: The present invention provides a process for the preparation of the carbapenem antibiotic of formula (I) or its salt in amorphous form. Formula (I) wherein R represents hydrogen or COOM and M represents hydrogen or sodium.
Abstract translation: 本发明提供了制备式（I）的碳青霉烯类抗生素或其无定形形式的盐的方法。 式（I）其中R表示氢或COOM，M表示氢或钠。
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