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    Medical electrical electrodes with conductive polymer
    2.
    发明授权
    Medical electrical electrodes with conductive polymer 有权
    带导电聚合物的医用电极

    公开(公告)号：US08831748B2

    公开(公告)日：2014-09-09

    申请号：US12414265

    申请日：2009-03-30

    申请人： Mark T. Marshall ,  Teresa A. Whitman ,  Suping Lyu ,  Elizabeth K. Nagy ,  David S. Olson

    发明人： Mark T. Marshall ,  Teresa A. Whitman ,  Suping Lyu ,  Elizabeth K. Nagy ,  David S. Olson

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0563 ,  Y10T29/49117

    摘要： A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.

    摘要翻译： 医疗电极包括位于引线主体上方的细长导电线圈和与引线主体接触并位于细长导电线圈的各个线圈之间的导电聚合物材料。 在某些实施方案中，导电聚合物是注入导电填料（例如炭黑）的聚合物（例如硅酮）。 在某些实施例中，导电聚合物材料通常是等距的，细长导电线圈的各个线圈的外径。 通过在引线体的长度上滑动细长导电线圈来制造医用电极，将导电聚合物分散在螺旋线圈上，将管插入细长导电线圈上，将聚合物材料分布在细长导电线圈 ，加热管道，使管道围绕细长的导电线圈收缩，并取出管道。

    HEMODIALYSIS SYSTEM HAVING A FLOW PATH WITH A CONTROLLED COMPLIANT VOLUME
    3.
    发明申请
    HEMODIALYSIS SYSTEM HAVING A FLOW PATH WITH A CONTROLLED COMPLIANT VOLUME 审中-公开
    具有控制合格体积的流路的血液透析系统

    公开(公告)号：US20130199998A1

    公开(公告)日：2013-08-08

    申请号：US13565733

    申请日：2012-08-02

    申请人： Thomas D. Kelly ,  SuPing Lyu ,  Bryant J. Pudil ,  Thomas E. Meyer

    发明人： Thomas D. Kelly ,  SuPing Lyu ,  Bryant J. Pudil ,  Thomas E. Meyer

    IPC分类号： A61M1/16

    CPC分类号： A61M1/3482 ,  A61M1/1696 ,  A61M2202/0021 ,  A61M2202/0413

    摘要： Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.

    摘要翻译： 公开了用于执行肾脏替代疗法的系统和方法，其具有或使用透析器，控制组件，吸附剂盒和流体储存器，其被配置为适于被需要治疗的个体穿戴或携带的重量和尺寸。 用于执行肾脏替代治疗的系统具有受控的依从性透析电路，其中控制泵控制流体穿过透析膜的双向运动。 透析电路和用于循环血液的体外循环通过透析膜流体连通。 在体外循环和透析回路之间移动的流体通量由控制泵运行的速率改变，从而可以控制超滤速率和对流间隙。 该系统提供对吸附剂盒的入口和出口导电性的监测，以提供量化或监测吸附剂盒去除尿素的设施。

    System and Implantable Device for Treating Chronic Kidney Disease
    4.
    发明申请
    System and Implantable Device for Treating Chronic Kidney Disease 审中-公开
    用于治疗慢性肾脏疾病的系统和植入装置

    公开(公告)号：US20120289881A1

    公开(公告)日：2012-11-15

    申请号：US13462190

    申请日：2012-05-02

    申请人： SuPing Lyu ,  Thomas Edward Meyer ,  Mark Fredrick Daniels ,  Bryant J. Pudil

    发明人： SuPing Lyu ,  Thomas Edward Meyer ,  Mark Fredrick Daniels ,  Bryant J. Pudil

    IPC分类号： A61M1/16

    CPC分类号： A61M1/1678 ,  B01D61/18 ,  B01D61/28 ,  B01D63/084 ,  B01D2313/105

    摘要： An implantable dialysis device with a related medical system for intracorporeal dialysis and ultrafiltration of blood, and methods of use are described. The medical system includes an extracorporeal module, a cutaneous module, and an implantable module. Features of the implantable module facilitate delivery and flow of blood and dialysate through the medical system. A filter pack within the implantable module performs dialysis and ultrafiltration of blood. System cleansing is also described.

    摘要翻译： 描述了具有用于体内透析和血液超滤的相关医疗系统的植入式透析装置及其使用方法。 医疗系统包括体外模块，皮肤模块和可植入模块。 可植入模块的特征便于血液和透析液通过医疗系统的输送和流动。 可植入模块内的过滤器组件执行血液的透析和超滤。 还描述了系统清洁。

    Medical electrical electrodes with conductive polymer
    6.
    发明申请
    Medical electrical electrodes with conductive polymer 有权

    公开(公告)号：US20060241734A1

    公开(公告)日：2006-10-26

    申请号：US11113867

    申请日：2005-04-25

    申请人： Mark Marshall ,  Teresa Whitman ,  Suping Lyu ,  Elizabeth Nagy ,  David Olson

    发明人： Mark Marshall ,  Teresa Whitman ,  Suping Lyu ,  Elizabeth Nagy ,  David Olson

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0563 ,  Y10T29/49117

    摘要： A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.

    Hemodialysis system having a flow path with a controlled compliant volume
    7.
    发明授权
    Hemodialysis system having a flow path with a controlled compliant volume 有权

    公开(公告)号：US10695481B2

    公开(公告)日：2020-06-30

    申请号：US13565733

    申请日：2012-08-02

    申请人： Thomas D. Kelly ,  SuPing Lyu ,  Bryant J. Pudil ,  Thomas E. Meyer

    发明人： Thomas D. Kelly ,  SuPing Lyu ,  Bryant J. Pudil ,  Thomas E. Meyer

    IPC分类号： A61M1/34 ,  A61M1/16

    摘要： Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.