Permeant delivery system and methods for use thereof
    5.
    发明申请
    Permeant delivery system and methods for use thereof 审中-公开
    渗透输送系统及其使用方法

    公开(公告)号:US20070031495A1

    公开(公告)日:2007-02-08

    申请号:US11455899

    申请日:2006-06-19

    CPC classification number: A61K9/7053 A61K9/0009

    Abstract: Disclosed is a device for causing the transdermal flux of a per meant into a subject via at least one formed pathway through a skin layer of the subject. The device comprises a delivery reservoir comprising: i) a non-biodegradable matrix having a bottom surface and defining a plurality of conduits therein the matrix, at least a portion of the plurality of conduits being in communication with the bottom surface; and ii)an undissolved hydrophilic per meant disposed therein at least a portion of the plurality of conduits of the matrix, wherein the hydrophilic per meant can come in contact with subcutaneous fluid from the subject when the bottom surface of the matrix is positioned in fluid communication with the at least one formed pathway. Also disclosed are systems and methods for causing the transdermal flux of a per meant into a subject via at least one formed pathway through a skin layer of the subject.

    Abstract translation: 公开了一种用于通过穿过受试者的皮肤层的至少一个形成的途径使每个意图的经皮通量引入受试者的装置。 所述装置包括递送贮存器,其包括:i)具有底表面并且在其中限定所述基质中的多个导管的不可生物降解的基质,所述多个导管的至少一部分与所述底表面连通; 和ii)未溶解的亲水剂,其中每个意图在其中设置多个基质管道的至少一部分,其中,当基质的底表面位于流体连通中时,每个意图的亲水剂可以与来自受试者的皮下流体接触 与至少一个形成的途径。 还公开了用于通过穿过受试者的皮肤层的至少一个形成的途径使每个意图的经皮通量引入受试者的系统和方法。

    Transdermal Porator and Patch System and Method for Using Same
    7.
    发明申请
    Transdermal Porator and Patch System and Method for Using Same 有权
    透皮移植器和贴片系统及其使用方法

    公开(公告)号:US20150190074A1

    公开(公告)日:2015-07-09

    申请号:US14147263

    申请日:2014-01-03

    Applicant: Stuart McRae

    Inventor: Stuart McRae

    Abstract: A transdermal permeant delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substate.

    Abstract translation: 将至少一种渗透性组合物的透皮渗透物递送到受试者的组织膜中,所述组织膜包括一次性基底,其具有连接到所述基底的上表面的第一释放衬垫的底表面的至少一部分和具有背衬层 以及可从第一释放衬垫的顶表面选择性地移除的储存器。 在连接位置,贴片的背衬层的第一部分可释放地安装到第一剥离衬垫的顶表面,与子层的引孔区间隔开对准。

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