公开(公告)号：US20140011823A1

公开(公告)日：2014-01-09

申请号：US14005046

申请日：2012-03-13

申请人： Toru Miura ,  Seiichi Sato ,  Hajime Yamada ,  Junya Tagashira ,  Toshiaki Watanabe ,  Ryohei Sekimoto ,  Rie Ishida ,  Hitomi Aoki ,  Tadaaki Ohgiya

发明人： Toru Miura ,  Seiichi Sato ,  Hajime Yamada ,  Junya Tagashira ,  Toshiaki Watanabe ,  Ryohei Sekimoto ,  Rie Ishida ,  Hitomi Aoki ,  Tadaaki Ohgiya

IPC分类号： C07D413/14 ,  C07D401/14

CPC分类号： C07D413/14 ,  A61K31/506 ,  C07D401/14

摘要： The present invention provides: a compound represented by general formula (I) below, that has both angiotensin II receptor antagonism and a PPARγ activation effect and that is useful as a preventative and/or therapeutic agent for high blood pressure, cardiac disease, arteriosclerosis, type-2 diabetes, and the like; and a drug composition containing the compound. General formula (I) (in the formula: ring A represents a pyridine ring; ring B represents a tetrazole ring or an oxadiazol-5(4H)-one ring; X represents C—R5 or a nitrogen atom; R1 represents an alkyl group; R2 represents an alkyl group or a cycloalkyl group; and R3, R4, and R5 each independently represents a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group or similar.

摘要翻译： 本发明提供：下述通式（I）表示的化合物，既具有血管紧张素II受体拮抗作用又具有PPARγ活化作用，可用作高血压，心脏病，动脉硬化等的预防和/或治疗剂， 2型糖尿病等; 和含有该化合物的药物组合物。 通式（I）（式中，环A表示吡啶环;环B表示四唑环或恶二唑-5（4H） - 酮环; X表示C-R5或氮原子; R1表示烷基 ; R 2表示烷基或环烷基; R 3，R 4和R 5各自独立地表示氢原子，卤素原子，烷基，烷氧基等。

公开(公告)号：US08420242B2

公开(公告)日：2013-04-16

申请号：US12351012

申请日：2009-01-09

申请人： Seiichi Sato

发明人： Seiichi Sato

IPC分类号： H01M2/36 ,  H01M2/12 ,  H01M2/24

CPC分类号： H01M2/1077 ,  H01M2/1211 ,  H01M10/052 ,  Y02E60/122 ,  Y02P70/54

摘要： A cell module has a cell group with a plurality of cells connected to each other. The module comprises a bus bar plate including a bus bar connecting between the cells and an end cover for covering the bus bar plate. The cell module is configure to be fixed with the end cover.

摘要翻译： 单元模块具有具有彼此连接的多个单元的单元组。 模块包括汇流条板，其包括连接在单元之间的母线和用于覆盖汇流条板的端盖。 电池模块配置为与端盖固定。

公开(公告)号：US08348384B2

公开(公告)日：2013-01-08

申请号：US13055196

申请日：2010-03-04

申请人： Seiichi Sato ,  Mitsuru Yahagi

发明人： Seiichi Sato ,  Mitsuru Yahagi

IPC分类号： B41J23/00

CPC分类号： B41J29/38 ,  B41J25/003

摘要： There is provided a small-sized and inexpensive rotational adjustment apparatus for a linearly moveable inkjet coating head 6 without providing a rotary mechanism which is separate from and independent of a linear movement mechanism. The apparatus is capable of performing a rotational adjustment, about a rotary axis in a Z-axis direction, of the inkjet coating head in which the Z-axis direction is orthogonal to an X-axis direction which is a direction of movement of the coating head. The apparatus has: first and second moveable bodies, two in total, which are linearly moved by separate driving sources in the X-axis direction; and a converting mechanism which converts the inkjet coating head into a linear movement in the X-axis direction when the first and second moveable bodies synchronously move in the X-axis direction, and into a rotary movement, about the rotary axis of the inkjet coating head, when both the first and the second moveable bodies make a relative movement in the X-axis direction.

摘要翻译： 提供了一种用于可直线移动的喷墨涂覆头6的小型和便宜的旋转调节装置，而不提供与线性运动机构分离并独立于其的旋转机构。 该装置能够沿着Z轴方向与作为涂层的移动方向的X轴方向正交的喷墨涂布头进行围绕Z轴方向的旋转轴的旋转调整 头。 该装置具有：第一和第二可移动体，总共两个，它们在X轴方向上由单独的驱动源线性移动; 以及转换机构，当第一和第二可移动体在X轴方向上同步移动时，将喷墨涂布头在X轴方向上转换成线性运动，并且围绕喷墨涂层的旋转轴旋转运动 当第一和第二可移动体都在X轴方向上相对移动时，头部。

公开(公告)号：US08273766B2

公开(公告)日：2012-09-25

申请号：US12531318

申请日：2008-04-03

申请人： Seiichi Sato ,  Junya Tagashira ,  Shunji Takemura ,  Yoshiharu Miyake ,  Tetsuya Ishikawa ,  Toshiharu Arai ,  Takahiro Ito ,  Takuya Hara

发明人： Seiichi Sato ,  Junya Tagashira ,  Shunji Takemura ,  Yoshiharu Miyake ,  Tetsuya Ishikawa ,  Toshiharu Arai ,  Takahiro Ito ,  Takuya Hara

IPC分类号： C07D217/18 ,  A61K31/47

CPC分类号： C07D217/04 ,  A61K31/472 ,  A61K31/4725 ,  C07D217/02 ,  C07D217/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D417/12

摘要： The present invention relates a specific tetrahydroisoquinoline compound which is useful as a chemokine receptor type 3 (CCR3) antagonist, and a pharmaceutical composition comprising the same as an active ingredient. The tetrahydroisoquinoline compound of the present invention is useful for the treatment or prevention of a disease in which CCR3 participates.

摘要翻译： 本发明涉及可用作3型趋化因子受体（CCR3）拮抗剂的特定四氢异喹啉化合物，以及包含其作为活性成分的药物组合物。 本发明的四氢异喹啉化合物可用于治疗或预防CCR3参与的疾病。

公开(公告)号：US08221881B2

公开(公告)日：2012-07-17

申请号：US12823314

申请日：2010-06-25

申请人： Seiichi Sato ,  Keisaku Kimura ,  Takashi Kawasaki ,  Takuya Okada

发明人： Seiichi Sato ,  Keisaku Kimura ,  Takashi Kawasaki ,  Takuya Okada

IPC分类号： B32B5/16 ,  B32B19/00

CPC分类号： C01B33/029 ,  C01B33/021 ,  Y10T428/25 ,  Y10T428/259 ,  Y10T428/268 ,  Y10T428/29 ,  Y10T428/298 ,  Y10T428/2982

摘要： A production method, comprising a step of synthesizing silicon particle-containing silicon oxide particles by performing a gas phase reaction of monosilane gas and oxidizing gas for oxidizing the monosilane gas and a step of removing the silicon oxide with hydrofluoric acid after holding the silicon oxide particle powder in an inert atmosphere at 800-1400° C., provides high-purity silicon nanoparticles which are highly practical as material powder for high-performance light-emitting elements and electronic parts in an industrial scale.

摘要翻译： 一种制造方法，包括通过进行甲硅烷气体的氧相反应和氧化单硅烷气体的氧化气体合成含硅粒子的氧化硅粒子的工序，以及在保持氧化硅粒子之后用氢氟酸除去氧化硅的工序 粉末在800-1400℃的惰性气氛中，提供高纯度的硅纳米颗粒，其作为用于工业规模的高性能发光元件和电子部件的材料粉末非常实用。

公开(公告)号：US20120165353A1

公开(公告)日：2012-06-28

申请号：US13394266

申请日：2010-09-29

申请人： Toru Miura ,  Seiichi Sato ,  Hajime Yamada ,  Junya Tagashira ,  Ryohei Sekimoto ,  Rie Ishida ,  Hitomi Aoki ,  Tadaaki Ohgiya

发明人： Toru Miura ,  Seiichi Sato ,  Hajime Yamada ,  Junya Tagashira ,  Ryohei Sekimoto ,  Rie Ishida ,  Hitomi Aoki ,  Tadaaki Ohgiya

IPC分类号： A61K31/506 ,  C07D413/14 ,  A61P9/00 ,  A61P13/12 ,  A61P3/10 ,  A61P9/10 ,  A61P9/12 ,  C07D401/14 ,  A61P3/00

CPC分类号： C07D401/14 ,  A61K31/422 ,  A61K31/4427 ,  C07D413/14

摘要： Disclosed are: a novel compound which has both an antagonistic activity on an angiotensin II receptor and a PPARγ-activating activity and is therefore useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, arteriosclerosis, type-2 diabetes, diabetic complications, metabolic syndrome or the like; and a pharmaceutical composition containing the compound. Specifically disclosed are: a compound represented by general formula (I) (wherein the ring A represents a pyridine ring; the ring B represents a tetrazole ring or an oxadiazol-5(4H)-one ring; X represents C—R5 or a nitrogen atom; R1 represents a C1-6 alkyl group; R2 represents a C1-6 alkyl group or a C3-8 cycloalkyl group; and R3, R4, R5 independently represent a hydrogen atom, a halogen atom, a C1-6 alkyl group, a halo-C1-6 alkyl group, or a C1-6 alkoxy group which may have a substituent), a salt of the compound, or a solvate of the compound or the salt; and a pharmaceutical composition containing the compound, the salt or the solvate.

摘要翻译： 公开了一种对血管紧张素II受体具有拮抗作用和PPARγ活化活性的新型化合物，因此可用作高血压，心脏病，动脉硬化，2型糖尿病，糖尿病并发症的预防和/或治疗剂 ，代谢综合征等; 和含有该化合物的药物组合物。 具体公开的是：由通式（I）表示的化合物（其中环A表示吡啶环;环B表示四唑环或恶二唑-5（4H） - 酮环; X表示C-R5或氮 原子; R1表示C1-6烷基; R2表示C1-6烷基或C3-8环烷基; R3，R4，R5分别表示氢原子，卤素原子，C1-6烷基， 卤代C 1-6烷基或可具有取代基的C 1-6烷氧基），化合物的盐或化合物或其盐的溶剂合物; 和含有该化合物，该盐或溶剂化物的药物组合物。

公开(公告)号：US20120094399A1

公开(公告)日：2012-04-19

申请号：US13378749

申请日：2009-06-18

申请人： Kazuhiro Yamamuro ,  Seiichi Sato ,  Mitsuru Yahagi ,  Junpei Yuyama ,  Kyuzo Nakamura

发明人： Kazuhiro Yamamuro ,  Seiichi Sato ,  Mitsuru Yahagi ,  Junpei Yuyama ,  Kyuzo Nakamura

IPC分类号： H01L21/66

CPC分类号： H01L31/03921 ,  H01L31/186 ,  Y02E10/50 ,  Y02P70/521

摘要： A photovoltaic cell manufacturing method includes: forming a photoelectric converter including a plurality of compartment elements, the compartment elements adjacent to each other being electrically connected; determining the compartment element having a structural defect in the photoelectric converter; narrowing down a region in which the structural defect exists in the compartment element based on a resistance distribution which is obtained by measuring resistances of a plurality of portions between the compartment elements adjacent to each other, image-capturing the inside of the narrowed region in which the structural defect exists by use of an image capturing section, accurately determining a position of the structural defect from the obtained image so that a portion in which the structural defect exists in the compartment element is restricted; and removing the structural defect by irradiating the portion in which the structural defect exists with a laser beam.

摘要翻译： 光电池制造方法包括：形成包括多个隔室元件的光电转换器，彼此相邻的隔室元件电连接; 确定在光电转换器中具有结构缺陷的隔室元件; 基于通过测量彼此相邻的隔间元件之间的多个部分的电阻而获得的电阻分布，使隔室元件中存在结构缺陷的区域变窄，图像捕获其中窄带区域的内部 通过使用图像捕获部分存在结构缺陷，从所获得的图像精确地确定结构缺陷的位置，使得限制了在隔室元件中存在结构缺陷的部分; 并通过用激光束照射存在结构缺陷的部分来去除结构缺陷。

公开(公告)号：US20110237590A1

公开(公告)日：2011-09-29

申请号：US13131561

申请日：2009-11-27

申请人： Takahiro Kitamura ,  Hajime Yamada ,  Shunji Takemura ,  Masanori Ashikawa ,  Tetsuya Ishikawa ,  Yoshiharu Miyake ,  Akiyasu Kouketsu ,  Seiichi Sato ,  Hiroyuki Ishiwata ,  Yuichiro Tabunoki ,  Manabu Shibasaki ,  Takatoshi Ozawa ,  Ryota Shigemi ,  Takeshi Doi ,  Masahiro Tamura

发明人： Takahiro Kitamura ,  Hajime Yamada ,  Shunji Takemura ,  Masanori Ashikawa ,  Tetsuya Ishikawa ,  Yoshiharu Miyake ,  Akiyasu Kouketsu ,  Seiichi Sato ,  Hiroyuki Ishiwata ,  Yuichiro Tabunoki ,  Manabu Shibasaki ,  Takatoshi Ozawa ,  Ryota Shigemi ,  Takeshi Doi ,  Masahiro Tamura

IPC分类号： A61K31/5377 ,  C07D213/74 ,  C07D401/12 ,  C07D413/12 ,  C07D211/46 ,  A61K31/44 ,  A61K31/497 ,  A61K31/4545 ,  A61P37/02 ,  A61P37/06

CPC分类号： C07D213/82 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

摘要： To provide a novel JAK3 inhibitor that is useful as a preventive and/or therapeutic agent for rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjögren syndrome, Behcet's disease, type I diabetes mellitus, autoimmune thyroiditis, idiopathic thrombocytopenic purpura, ulcerative colitis, Crohn's disease, asthma, allergic rhinitis, atopic dermatitis, contact dermatitis, urticaria, eczema, psoriasis, allergic conjunctivitis, uveitis, cancer, leukemia and the like. The pyridine-3-carboxyamide derivative represented by the general formula (1): or its salt or a solvate thereof.

摘要翻译： 提供可用作器官移植，类风湿关节炎，多发性硬化症，系统性红斑狼疮，Sjögren综合征，Behcet氏病，I型糖尿病的排斥反应和宿主疾病（GvHD）的预防和/或治疗剂的新型JAK3抑制剂 过敏性甲状腺炎，特发性血小板减少性紫癜，溃疡性结肠炎，克罗恩病，哮喘，过敏性鼻炎，特应性皮炎，接触性皮炎，荨麻疹，湿疹，牛皮癣，过敏性结膜炎，葡萄膜炎，癌症，白血病等。 由通式（1）表示的吡啶-3-甲酰胺衍生物或其盐或其溶剂合物。

公开(公告)号：US20090181288A1

公开(公告)日：2009-07-16

申请号：US12351012

申请日：2009-01-09

申请人： Seiichi SATO

发明人： Seiichi SATO

IPC分类号： H01M2/12 ,  H01M6/42

CPC分类号： H01M2/1077 ,  H01M2/1211 ,  H01M10/052 ,  Y02E60/122 ,  Y02P70/54

摘要： A cell module has a cell group with a plurality of cells connected to each other. The module comprises a bus bar plate including a bus bar connecting between the cells and an end cover for covering the bus bar plate. The cell module is configure to be fixed with the end cover.

摘要翻译： 单元模块具有具有彼此连接的多个单元的单元组。 模块包括汇流条板，其包括连接在单元之间的母线和用于覆盖汇流条板的端盖。 电池模块配置为与端盖固定。

公开(公告)号：US20090166338A1

公开(公告)日：2009-07-02

申请号：US12296546

申请日：2006-04-11

申请人： Seiichi Sato

发明人： Seiichi Sato

IPC分类号： B23K9/04

CPC分类号： B23K9/0061 ,  B23K9/0284 ,  B23K9/32 ,  B23K9/326 ,  B23K37/0276 ,  F16L13/02 ,  F16L55/134 ,  F16L55/18

摘要： A preserving apparatus for preserving welded joint portions 7, 8 by deposit welding on the inner surface of the welded joint portions 7, 8, in which a nozzle 4 and a pipe 5 supported under water are joined, the apparatus having: a seal member 9 that is disposed in front and behind the welded joint portions 7, 8 to be deposit welded within the nozzle 4 and pipe 5, and serves to demarcate and form a closed operation area A within the nozzle 4 and pipe 5; water drainage means 12 for draining the inside of the operation area A demarcated and formed by the seal member 9 and obtaining a gas atmosphere therein; and welding means 13 for deposit welding on the inner surface of the welded joint portions 7, 8 within the operation area A in which the gas atmosphere has been created.

摘要翻译： 一种保存装置，用于通过在焊接接头部分7,8的内表面上通过沉积焊接来保持焊接接头部分7,8，其中喷嘴4和支撑在水下的管道5接合，该设备具有：密封部件9 设置在焊接接头部分7,8的前面和后面，以在喷嘴4和管道5中沉积焊接，并用于在喷嘴4和管道5内划定并形成封闭的操作区域A. 排水装置12，用于排出由密封构件9划分并形成的操作区域A的内部，并在其中获得气体气氛; 以及在已经形成气体气氛的操作区域A中的焊接接头部分7,8的内表面上的用于沉积焊接的焊接装置13。