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公开(公告)号：US20060287389A1
公开(公告)日：2006-12-21
申请号：US11426657
申请日：2006-06-27
Applicant: Keith BIGGADIKE , Diane Coe , Dean Edney , Stephen Guntrip , Abigail Halton , Brian Looker , Michael Monteith , Rebecca Moore , Rajnikant Patel , Panayiotis Procopiou
Inventor： Keith BIGGADIKE , Diane Coe , Dean Edney , Stephen Guntrip , Abigail Halton , Brian Looker , Michael Monteith , Rebecca Moore , Rajnikant Patel , Panayiotis Procopiou
IPC: C07C311/02 , A61K31/24 , A61K31/18 , A61K31/573
CPC classification number: C07D295/26 , C07C311/27 , C07C311/29 , C07C311/58 , C07C2601/04 , C07C2601/14 , C07D295/13
Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
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公开(公告)号：US20060205794A1
公开(公告)日：2006-09-14
申请号：US10532869
申请日：2003-10-24
Applicant: Alan Chapman , Stephen Guntrip , Brian Looker , Panayiotis Procopiou
Inventor： Alan Chapman , Stephen Guntrip , Brian Looker , Panayiotis Procopiou
IPC: A61K31/44 , A61K31/42 , A61K31/35 , A61K31/138 , A61K31/165
CPC classification number: C07D213/66 , C07C317/22 , C07C323/19 , C07C2601/08 , C07C2601/14 , C07D213/65 , C07D215/227 , C07D215/26 , C07D261/10 , C07D263/22 , C07D309/40 , C07D319/08
Abstract: The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
Abstract translation: 本发明涉及式（I）的新化合物，其制备方法，含有它们的药物组合物及其在治疗中的用途，特别是其在预防和治疗呼吸系统疾病中的用途。
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公开(公告)号：US20080003290A1
公开(公告)日：2008-01-03
申请号：US11566346
申请日：2006-12-04
Applicant: Philip Box , Diane Coe , Brian Looker , Inderjit Mann , Panayiotis Procopiou
Inventor： Philip Box , Diane Coe , Brian Looker , Inderjit Mann , Panayiotis Procopiou
IPC: A61K31/42 , A61K9/14 , A61M15/00 , A61P11/00 , C07D413/00
CPC classification number: C07D213/82 , C07C217/08 , C07C217/76 , C07C233/75 , C07C237/42 , C07C271/38 , C07C275/32 , C07C275/40 , C07C311/08 , C07C311/21 , C07C311/29 , C07C317/14 , C07C317/22 , C07C2601/02 , C07C2601/08 , C07D239/54 , C07D333/70 , C07D513/04
Abstract: The present invention relates to novel compounds of formula (1), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory disease.
Abstract translation: 本发明涉及式（1）的新化合物，其制备方法，含有它们的药物组合物及其在治疗中的用途，特别是其在预防和治疗呼吸系统疾病中的用途。
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4.发明申请Methods using phenethanolamine derivatives for treatment of respiratory diseases 失效使用苯乙醇胺衍生物治疗呼吸系统疾病的方法公开(公告)号：US20070004807A1
公开(公告)日：2007-01-04
申请号：US11207967
申请日：2005-08-19
Applicant: Keith Biggadike , Diane Coe , Dean Edney , Stephen Guntrip , Abigai Halton , Brian Looker , Michael Monteith , Rebecca Moore , Rajnikant Patel , Panayiotis Procopiou
Inventor： Keith Biggadike , Diane Coe , Dean Edney , Stephen Guntrip , Abigai Halton , Brian Looker , Michael Monteith , Rebecca Moore , Rajnikant Patel , Panayiotis Procopiou
IPC: A61K31/18 , C07C311/35
CPC classification number: C07D295/26 , C07C311/27 , C07C311/29 , C07C311/58 , C07C2601/04 , C07C2601/14 , C07D295/13
Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
Abstract translation: 本发明涉及式（I）的新化合物，其制备方法，含有它们的药物组合物及其在治疗中的用途，特别是其在预防和治疗呼吸系统疾病中的用途。
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公开(公告)号：US20060148771A1
公开(公告)日：2006-07-06
申请号：US10544869
申请日：2004-02-12
Applicant: Keith Biggadike , Philip Box , Diane Coe , Duncan Holmes , Brian Looker , Panayiotis Procopiou
Inventor： Keith Biggadike , Philip Box , Diane Coe , Duncan Holmes , Brian Looker , Panayiotis Procopiou
IPC: A61K31/58 , A61K31/538 , A61K31/4704 , A61K31/428 , A61K31/549 , A61K31/405 , A61K31/35 , A61K31/325 , A61K31/225 , A61K31/138
CPC classification number: C07D213/65 , C07C217/28
Abstract: A compound of formula (I) or a salt, solvate, or physiologically functional derivative thereof, wherein: m is an integer of from 2 to 8; n is an integer of from 2 to 5; with the proviso that m+n is 4 to 10; R4 and R5 are independently selected from hydrogen and C1-4alkyl with the proviso that the total number of carbon atoms in R4 and R5 is not more than 4; R6 and R7 are independently selected from hydrogen and C1-4alkyl with the proviso that the total number of carbon atoms in R6 and R7 is not more than 4, and Ar1 is a group selected from (a), (b), (c) and (d).
Abstract translation: 式（I）化合物或其盐，溶剂合物或生理功能衍生物，其中：m为2至8的整数; n为2〜5的整数， 条件是m + n为4至10; R 4和R 5独立地选自氢和C 1-4 - 烷基，条件是R 3中的碳原子总数 SUP> 4和R 5不超过4; R 6和R 7独立地选自氢和C 1-4 - 烷基，条件是R 1中的碳原子总数 SUP> 6和R 7不超过4，Ar 1是选自（a），（b），（c）和 （d）。
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Patent Agency Ranking
公开(公告)号：US20060287286A1
公开(公告)日：2006-12-21
申请号：US11426661
申请日：2006-06-27
Applicant: Keith BIGGADIKE , Diane Coe , Dean Edney , Stephen Guntrip , Abigail Halton , Brian Looker , Michael Monteith , Rebecca Moore , Rajnikant Patel , Panayiotis Procopiou
Inventor： Keith BIGGADIKE , Diane Coe , Dean Edney , Stephen Guntrip , Abigail Halton , Brian Looker , Michael Monteith , Rebecca Moore , Rajnikant Patel , Panayiotis Procopiou
IPC: A61K31/573 , A61K31/18
CPC classification number: C07D295/26 , C07C311/27 , C07C311/29 , C07C311/58 , C07C2601/04 , C07C2601/14 , C07D295/13
Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
Abstract translation: 本发明涉及式（I）的新化合物，其制备方法，含有它们的药物组合物及其在治疗中的用途，特别是其在预防和治疗呼吸系统疾病中的用途。
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公开(公告)号：US20050209338A1
公开(公告)日：2005-09-22
申请号：US10506173
申请日：2003-02-27
Applicant: Keith Blake , Diane Coe , Panayiotis Procopiou
Inventor： Keith Blake , Diane Coe , Panayiotis Procopiou
IPC: A61K31/17 , A61K31/4184 , A61K31/4406 , A61K31/505 , A61K45/00 , A61P1/04 , A61P5/40 , A61P9/04 , A61P11/00 , A61P11/02 , A61P11/06 , A61P15/06 , A61P17/00 , A61P17/06 , A61P25/02 , A61P25/24 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/08 , A61P43/00 , C07B61/00 , C07C273/18 , C07C275/24 , C07C275/26 , C07C275/30 , C07C275/32 , C07C275/34 , C07C275/50 , C07D213/75 , C07D235/26 , C07D239/42
CPC classification number: C07D239/42 , C07C275/24 , C07C275/26 , C07C275/30 , C07C275/32 , C07C275/34 , C07C275/50 , C07C2601/10 , C07C2601/14 , C07D213/75 , C07D235/26
Abstract: The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
Abstract translation: 本发明涉及式（I）的新化合物，其制备方法，含有它们的药物组合物及其在治疗中的用途，特别是其在预防和治疗呼吸系统疾病中的用途。
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公开(公告)号：US20070249630A1
公开(公告)日：2007-10-25
申请号：US11766879
申请日：2007-06-22
Applicant: Keith BLAKE , Diane COE , Panayiotis PROCOPIOU
Inventor： Keith BLAKE , Diane COE , Panayiotis PROCOPIOU
IPC: A61K31/195 , A61K31/4164 , A61K31/44 , A61P11/00 , C07C63/00 , C07D239/02
CPC classification number: C07D239/42 , C07C275/24 , C07C275/26 , C07C275/30 , C07C275/32 , C07C275/34 , C07C275/50 , C07C2601/10 , C07C2601/14 , C07D213/75 , C07D235/26
Abstract: The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
Abstract translation: 本发明涉及式（I）的新化合物，其制备方法，含有它们的药物组合物及其在治疗中的用途，特别是其在预防和治疗呼吸系统疾病中的用途。
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公开(公告)号：US20050256201A1
公开(公告)日：2005-11-17
申请号：US10512232
申请日：2003-04-24
Applicant: Philip Box , Diane Coe , Brian Looker , Panayiotis Procopiou
Inventor： Philip Box , Diane Coe , Brian Looker , Panayiotis Procopiou
IPC: C07D307/68 , A61K31/137 , A61K31/166 , A61K31/167 , A61K31/17 , A61K31/18 , A61K31/192 , A61K31/341 , A61K31/455 , A61P1/04 , A61P9/00 , A61P11/00 , A61P11/06 , A61P11/08 , A61P15/06 , A61P17/00 , A61P17/06 , A61P21/00 , A61P25/02 , A61P25/24 , A61P27/16 , A61P43/00 , C07C217/56 , C07C217/60 , C07C219/28 , C07C233/25 , C07C235/42 , C07C255/54 , C07C275/32 , C07C275/40 , C07C279/18 , C07C307/06 , C07C307/10 , C07C311/04 , C07C311/08 , C07C311/29 , C07C313/06 , C07C317/22 , C07D213/82 , C07F7/18 , A61K31/16 , A61K31/138 , C07C217/64
CPC classification number: C07C275/32 , C07C217/60 , C07C233/25 , C07C235/42 , C07C255/54 , C07C279/18 , C07C307/10 , C07C311/08 , C07C311/29 , C07C317/22 , C07C2601/08 , C07C2601/14
Abstract: The present invention relates to novel compounds of formula (I), or a salt, solvate, or physiologically functional derivative thereof, to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
Abstract translation: 本发明涉及新的式（I）化合物或其盐，溶剂合物或生理功能衍生物，其制备方法，含有它们的药物组合物及其在治疗中的用途，特别是其用于 预防和治疗呼吸系统疾病。
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公开(公告)号：US20050075394A1
公开(公告)日：2005-04-07
申请号：US10489569
申请日：2002-09-11
Applicant: Philip Box , Diane Coe , Brian Looker , Inderjit Mann , Panayiotis Procopiou
Inventor： Philip Box , Diane Coe , Brian Looker , Inderjit Mann , Panayiotis Procopiou
IPC: C07D213/56 , A61K31/17 , A61K31/18 , A61K31/222 , A61K31/44 , A61K31/455 , A61K45/00 , A61P1/04 , A61P9/04 , A61P11/00 , A61P11/06 , A61P15/00 , A61P17/00 , A61P17/02 , A61P17/06 , A61P21/00 , A61P25/24 , A61P37/08 , A61P43/00 , C07C213/02 , C07C213/08 , C07C217/08 , C07C217/76 , C07C233/75 , C07C237/42 , C07C271/38 , C07C275/32 , C07C275/40 , C07C311/08 , C07C311/21 , C07C311/29 , C07C317/14 , C07C317/22 , C07D213/82 , C07D239/54 , C07D333/70 , C07D413/12 , C07D513/04 , A61K31/325 , A61K31/195
CPC classification number: C07D213/82 , C07C217/08 , C07C217/76 , C07C233/75 , C07C237/42 , C07C271/38 , C07C275/32 , C07C275/40 , C07C311/08 , C07C311/21 , C07C311/29 , C07C317/14 , C07C317/22 , C07C2601/02 , C07C2601/08 , C07D239/54 , C07D333/70 , C07D513/04
Abstract: The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
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