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公开(公告)号：US20220143285A1
公开(公告)日：2022-05-12
申请号：US17522778
申请日：2021-11-09
申请人： OUTSET MEDICAL, INC.
发明人： Dean HU , Logan RIVAS
IPC分类号： A61M1/16
摘要： Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysis fluid solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy.
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公开(公告)号：US20210244869A1
公开(公告)日：2021-08-12
申请号：US17244672
申请日：2021-04-29
申请人： OUTSET MEDICAL, INC.
发明人： Michael Edward HOGARD , Dean HU , Shih-Paul CHEN , James RITSON , Gopi K. LINGAM , Peter Velasco OBICO , James R. CURTIS , Steven M. MILLER
摘要： Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy. For example, the dialysis systems include disposable cartridge and patient tubing sets that are easily installed on the dialysis system and automatically align the tubing set, sensors, venous drip chamber, and other features with the corresponding components on the dialysis system. Methods of use are also provided, including automated priming sequences, blood return sequences, and dynamic balancing methods for controlling a rate of fluid transfer during different types of dialysis, including hemodialysis, ultrafiltration, and hemodiafiltration.
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公开(公告)号：US20150328386A1
公开(公告)日：2015-11-19
申请号：US14808827
申请日：2015-07-24
IPC分类号： A61M1/16 , B01D61/58 , B01D61/08 , C02F1/02 , C02F1/00 , C02F1/28 , C02F1/44 , C02F1/20 , C02F9/00 , B01D61/18
CPC分类号： A61M1/1686 , A61M1/1658 , A61M1/1672 , A61M2205/75 , B01D61/025 , B01D61/08 , B01D61/145 , B01D61/18 , B01D61/30 , B01D61/58 , B01D2311/04 , B01D2311/06 , B01D2311/25 , C02F1/001 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/005 , C02F2209/006 , C02F2209/03 , C02F2301/043 , C02F2301/046 , C02F2303/04 , F24H1/121 , B01D2311/2649 , B01D2311/103 , B01D2311/2653
摘要： Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.
摘要翻译： 某些公开的实施方案涉及制备在家用透析系统中使用的透析液的系统和方法，该系统和方法相对于现有系统而言紧凑且重量轻并且消耗相对低的能量。 该方法包括将家用水流连接到透析系统; 过滤水流; 在非分批方法中将水流加热到至少约138摄氏度以产生加热的水流; 将加热的水流维持在至少约138摄氏度以上至少约2秒; 冷却加热的水流以产生冷却的水流; 超滤冷却水流; 并以非分批方法将透析液组分混合到冷却水流中。
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公开(公告)号：US20230347035A1
公开(公告)日：2023-11-02
申请号：US18059181
申请日：2022-11-28
申请人： Outset Medical, Inc.
发明人： James RITSON , Michael Edward HOGARD , Gopi K. LINGAM , Shih-Paul CHEN , Dean HU
CPC分类号： A61M1/287 , A61M1/1656 , A61M1/168 , A61M1/1686 , A61M1/28 , A61M5/1452 , A61M5/1454 , A61M5/158 , C02F9/00 , C02F2103/026
摘要： Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.
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公开(公告)号：US20190192758A1
公开(公告)日：2019-06-27
申请号：US16325664
申请日：2017-08-21
申请人： OUTSET MEDICAL, INC.
发明人： James RITSON , Michael Edward HOGARD , Gopi K. LINGAM , Shih-Paul CHEN , Dean HU
CPC分类号： A61M1/287 , A61M1/1656 , A61M1/168 , A61M1/1686 , A61M1/28 , C02F1/001 , C02F1/283 , C02F1/42 , C02F1/441 , C02F1/444 , C02F9/00 , C02F2103/026
摘要： Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure in provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.
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公开(公告)号：US09545469B2
公开(公告)日：2017-01-17
申请号：US15225712
申请日：2016-08-01
申请人： OUTSET MEDICAL, INC.
发明人： James R. Curtis , Ladislaus F. Nonn , Julie Wrazel
CPC分类号： A61M1/1647 , A61M1/16 , A61M1/1601 , A61M1/1619 , A61M1/165 , A61M1/34 , A61M1/3403 , A61M1/3413 , A61M1/3427 , A61M2205/3331 , A61M2205/3334 , A61M2205/70 , A61M2205/702 , G05D7/0676
摘要： Systems and methods are disclosed for performing hemodialysis that include fluid handling systems that provide accurate control over the type and level of hemodialysis being performed. The system includes a first pump for pumping dialysate into a dialyzer and a second pump for pumping dialysate out of the dialyzer. The system also includes a third pump that provides improved control of a level of ultrafiltration, hemodiafiltration, or both.
摘要翻译： 公开了用于执行血液透析的系统和方法，其包括提供对正在执行的血液透析的类型和水平的精确控制的流体处理系统。 该系统包括用于将透析液泵入透析器的第一泵和用于将透析液泵出透析器的第二泵。 该系统还包括第三泵，其提供对超滤水平，血液透析滤液或两者的改进的控制。
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公开(公告)号：US09328969B2
公开(公告)日：2016-05-03
申请号：US13645336
申请日：2012-10-04
申请人： Outset Medical, Inc.
发明人： Julie Wrazel , Gopi Lingam , Erik Miller , Clayton Hires
IPC分类号： A61M1/16 , F28F3/08 , C02F9/00 , B01D63/00 , F28D7/12 , C02F1/00 , C02F1/02 , C02F1/20 , C02F1/28 , C02F1/44 , C02F103/02
CPC分类号： F28F3/08 , A61M1/1635 , A61M1/1656 , A61M1/1662 , A61M2205/3633 , C02F1/001 , C02F1/02 , C02F1/20 , C02F1/283 , C02F1/441 , C02F1/444 , C02F9/005 , C02F2103/026 , C02F2209/03 , C02F2209/05 , C02F2209/40 , C02F2303/04 , C02F2303/185 , F28D7/12 , F28F2260/02 , Y02W10/37
摘要： Disclosed herein are small, lightweight, portable, systems that have the capability of reliably, reproducibly, highly efficiently and relatively inexpensively providing a source of purified water of sufficient volumes for home dialysis. In addition, the systems disclosed herein require much less purified water at any one time than the volumes typically needed for dialysis today, thereby further reducing the expense of running the system at home.
摘要翻译： 本文公开了小型，轻质的，便携式的系统，其具有可靠，可再现，高效率和相对便宜地为家庭透析提供足够体积的纯净水源的能力。 此外，本文公开的系统在任何一个时间要求比目前透析所需的体积通常少得多的净化水，从而进一步降低在家中运行系统的费用。
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公开(公告)号：US20220203004A1
公开(公告)日：2022-06-30
申请号：US17607637
申请日：2020-04-30
申请人： OUTSET MEDICAL, INC.
发明人： Dean HU , Justin Thomas PUZIN , Steven Owen MILLER , Tyler John MILLER , Logan RIVAS , Michael KIM , Michael Edward HOGARD , Jeffrey ETTER , Todd NELSON , James TUMBER , Stephanie KLUNK , Paul BRAYFORD , Cole NAYMARK
摘要： Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy.
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公开(公告)号：US20190022293A1
公开(公告)日：2019-01-24
申请号：US16138441
申请日：2018-09-21
IPC分类号： A61M1/16 , F24H1/12 , C02F1/02 , B01D61/08 , B01D61/18 , B01D61/30 , B01D61/58 , C02F1/00 , C02F1/20 , C02F1/28 , C02F1/44 , C02F9/00 , B01D61/14 , B01D61/02 , C02F103/02
摘要： Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.
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公开(公告)号：US10105476B2
公开(公告)日：2018-10-23
申请号：US14808827
申请日：2015-07-24
IPC分类号： A61M1/16 , B01D61/08 , B01D61/18 , C02F1/20 , C02F1/44 , B01D61/30 , C02F1/02 , C02F1/28 , C02F9/00 , F24H1/12 , B01D61/58 , C02F1/00 , B01D61/02 , B01D61/14 , C02F103/02
摘要： Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process.
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