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公开(公告)号：US20120220485A1
公开(公告)日：2012-08-30
申请号：US13467972
申请日：2012-05-09
申请人： Mamoru Tsukada
发明人： Mamoru Tsukada
CPC分类号： C12Q1/6881 , C12Q1/6827 , C12Q2600/156 , C12Q2537/143 , C12Q2535/131
摘要： Provided is a probe set that is useful for identifying each allele of HLA individually, and a method of identification of an allele of HLA by the use thereof for each type.The probe set is composed of probes that cover all of the partial sequences that contain a unique base to each allele. Using this probe set HLA contained in a specimen is identified.
摘要翻译： 提供了可用于识别HLA的每个等位基因的探针组，以及通过其每种类型的使用来鉴定HLA等位基因的方法。 探针组由覆盖所有部分序列的探针组成，每个部分序列含有每个等位基因的独特碱基。 确定样品中含有的探针组合HLA。
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公开(公告)号：US20080227191A1
公开(公告)日：2008-09-18
申请号：US12036853
申请日：2008-02-25
申请人： Mamoru Tsukada
发明人： Mamoru Tsukada
IPC分类号： C12M1/00
摘要： A vessel and an apparatus for culturing cells are provided in which a temperature difference is effected so that any position in the vessel can be brought into a temperature at which cells can be attached and a temperature at which cells cannot be attached, thereby freely selecting and recovering cells.
摘要翻译： 提供了一种用于培养细胞的容器和装置，其中进行温度差异，使得容器中的任何位置可以进入可以附着细胞的温度和细胞不能附着的温度，从而自由选择和 恢复细胞。
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公开(公告)号：US20080087336A1
公开(公告)日：2008-04-17
申请号：US11869415
申请日：2007-10-09
申请人： Susumu Yasuda , Mamoru Tsukada , Takahiro Ezaki
发明人： Susumu Yasuda , Mamoru Tsukada , Takahiro Ezaki
IPC分类号： F16L9/00
CPC分类号： B01F5/0256 , Y10T137/8593
摘要： The present invention provides a fluid-processing apparatus which can uniformly mix or react fluids with each other by discharging the fluids from many nozzles at a uniform discharge pressure to collide them. A fluid-processing apparatus that has a first unit provided with one inlet for supplying a fluid therethrough, N pieces of transportation paths which are branched into N pieces from one path leading to one inlet, and N pieces of outlets connecting to the N pieces of transportation paths, and a second unit provided with one inlet, N pieces of transportation paths, and N pieces of outlets so as to correspond to the first unit, includes bringing a first fluid which flows out from the outlet of the first unit into contact with a second fluid which flows out from the outlet of the second unit to mix and react the fluids with each other, wherein variations among lengths of the N pieces of the transportation paths in the first unit and lengths of the N pieces of transportation paths in the second unit are controlled into 20% or less.
摘要翻译： 本发明提供了一种流体处理装置，其能够以均匀的排出压力从许多喷嘴排出流体以使流体彼此均匀地混合或反应以使它们相互碰撞。 一种流体处理装置，具有第一单元，该第一单元设置有用于供给流体的一个入口，从通向一个入口的一个路径分支成N个的N个输送路径，以及连接到N个 输送路径以及与第一单元对应的具有一个入口，N个输送路径和N个出口的第二单元，包括使从第一单元的出口流出的第一流体与 第二流体，其从第二单元的出口流出，以使流体彼此混合和反应，其中第一单元中的N个输送路径的长度与第一单元中的N个输送路径的长度的变化 第二单位控制在20％以下。
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公开(公告)号：US20070099187A1
公开(公告)日：2007-05-03
申请号：US10556508
申请日：2004-05-13
申请人： Mamoru Tsukada
发明人： Mamoru Tsukada
CPC分类号： C12Q1/6837 , C12Q2600/156 , C12Q2525/117 , C12Q2525/119
摘要： A nucleic acid array is provided that can efficiently perform analysis, and further, can estimate the number of expressions of amino acid mutations for all cases by use of a smaller number of arrays. The nucleic acid array has a plurality of oligonucleotides immobilized on a substrate, wherein the oligonucleotide has a sequence site that forms base pairs with at least two bases of the four bases (A, T, C, G or U) or has a sequence site that does not form a base pair with any of the four bases.
摘要翻译： 提供了可以有效地执行分析的核酸阵列，并且还可以通过使用较少数量的阵列来估计所有病例的氨基酸突变的表达数目。 核酸阵列具有固定在底物上的多个寡核苷酸，其中寡核苷酸具有与四个碱基（A，T，C，G或U）的至少两个碱基形成碱基对的序列位点或具有序列位点 这不与四个碱基中的任何一个形成碱基对。
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公开(公告)号：US06302850B1
公开(公告)日：2001-10-16
申请号：US09392304
申请日：1999-09-08
申请人： Mamoru Tsukada
发明人： Mamoru Tsukada
IPC分类号： A61B502
CPC分类号： A61B3/1233
摘要： A fundus blood flow metering method includes a series of steps of carrying out alignment of the positional relation with an eye to be examined, carrying out aiming of a blood vessel to be measured, and measuring a velocity of blood flow while tracking the blood vessel so as to track and capture eye movement. After the sequential operation, the direction of incidence of a measuring beam is switched to another direction and the series of steps are again carried out for the same blood vessel, starting from the alignment.
摘要翻译： 眼底血流计量方法包括进行与待检眼睛的位置关系的对准的一系列步骤，进行待测血管的瞄准，并在跟踪血管的同时测量血流速度 跟踪和捕捉眼睛运动。 在顺序操作之后，将测量光束的入射方向切换到另一方向，并且从对准开始，对于相同的血管再次执行一系列步骤。
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公开(公告)号：US20100028861A1
公开(公告)日：2010-02-04
申请号：US10582327
申请日：2004-12-24
申请人： Mamoru Tsukada
发明人： Mamoru Tsukada
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6881 , C12Q1/6827 , C12Q2600/156 , C12Q2537/143 , C12Q2535/131
摘要： Provided is a probe set that is useful for identifying each allele of HLA individually, and a method of identification of an allele of HLA by the use thereof for each type. The probe set is composed of probes that cover all of the partial sequences that contain a unique base to each allele. Using this probe set HLA contained in a specimen is identified.
摘要翻译： 提供了可用于识别HLA的每个等位基因的探针组，以及通过其每种类型的使用来鉴定HLA等位基因的方法。 探针组由覆盖所有部分序列的探针组成，每个部分序列含有每个等位基因的独特碱基。 确定样品中含有的探针组合HLA。
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公开(公告)号：US20070060720A1
公开(公告)日：2007-03-15
申请号：US10562736
申请日：2004-07-02
CPC分类号： B32B27/04 , B32B15/08 , B32B15/20 , B32B27/38 , C08G59/621 , C08L63/00 , H05K1/0326 , C08L2666/16
摘要： An epoxy resin composition which comprises an epoxy resin (A) and a curing agent (B) for epoxy resins, wherein the curing agent (B) for epoxy resins comprises a phenol-based resin (F) which contains at least either of a structural unit (X) represented by a given general formula obtained by reacting a biphenyl isomer or a mixture of biphenyl isomers with a phenol-based compound and a structural unit (Y) represented by a given general formula obtained by reacting a benzene isomer or a mixture of benzene isomers with a phenol-based compound, the sum of the number of repetitions of the structural unit (X) and that of the structural unit (Y) (n or m+m′) being larger than 10 and smaller than 75.
摘要翻译： 一种环氧树脂组合物，其包含环氧树脂（A）和用于环氧树脂的固化剂（B），其中环氧树脂用固化剂（B）包含苯酚类树脂（F），其含有结构 通过使联苯异构体或联苯异构体的混合物与苯酚类化合物反应得到的给定通式表示的单元（X）和由苯异构体或混合物反应得到的给定通式所表示的结构单元（Y） 的苯异构体与苯酚类化合物的结构单元（X）的重复数与结构单元（Y）（n或m + m'）的重复数之和大于10且小于75。
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公开(公告)号：US20080108736A1
公开(公告)日：2008-05-08
申请号：US11720374
申请日：2005-11-28
申请人： Mamoru Tsukada
发明人： Mamoru Tsukada
IPC分类号： C08J3/05
CPC分类号： C09D11/322 , C09B41/001 , C09B41/003
摘要： A process for preparing an azo pigment dispersion, comprising the step of causing a solution containing a diazonium compound to react with a solution containing a coupling agent to prepare an azo pigment dispersion in which an azo pigment is dispersed, wherein the reaction is carried out in the presence of a dispersing agent for dispersing the azo pigment in a solvent and a pH buffering agent having a buffering action under alkaline conditions.
摘要翻译： 一种制备偶氮颜料分散体的方法，包括使含有重氮化合物的溶液与含有偶联剂的溶液反应以制备其中分散偶氮颜料的偶氮颜料分散体的步骤，其中反应在 存在用于将偶氮颜料分散在溶剂中的分散剂和在碱性条件下具有缓冲作用的pH缓冲剂。
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9.发明申请PCR amplification reaction apparatus and method for PCR amplification reaction using apparatus 有权PCR扩增反应装置及使用装置的PCR扩增反应方法公开(公告)号：US20050239119A1
公开(公告)日：2005-10-27
申请号：US11111904
申请日：2005-04-22
申请人： Mamoru Tsukada
发明人： Mamoru Tsukada
CPC分类号： C12Q1/686
摘要： The present invention provides a method for PCR amplification reaction that can reduce the time required for amplification reaction of nucleic acid by PCR using the target nucleotide molecule as a template, and an apparatus used for the method. The method comprises using a PCR reaction vessel in which a heater for local heating, which can thermally contact with a solution storing section with an extremely small capacity for storing a PCR reaction solution and a reaction solution stored in the solution storing section directly, is placed; feeding a pulsed current to the placed heater; and carrying out a thermal cycle of PCR reaction, so that high-speed PCR amplification reaction can be carried out.
摘要翻译： 本发明提供了可以通过使用靶核苷酸分子作为模板的PCR来减少核酸的扩增反应所需的时间的PCR扩增反应的方法，以及用于该方法的装置。 该方法包括使用PCR反应容器，其中放置可与用于储存PCR反应溶液的极小容量的溶液储存部分和存储在溶液存储部分中的反应溶液直接热接触的局部加热加热器 ; 向放置的加热器供给脉冲电流; 并进行PCR反应的热循环，可以进行高速PCR扩增反应。
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10.发明授权公开(公告)号：US08041512B2
公开(公告)日：2011-10-18
申请号：US11015003
申请日：2004-12-20
申请人： Mamoru Tsukada
发明人： Mamoru Tsukada
摘要： To provide a method of accurately and efficiently acquiring a candidate for a set of discrimination elements for identification. Provided is a method of acquiring a set of specific elements on a specific sequence for discriminating the specific sequence from a number of sequences, including the steps of acquiring a group of alignment data in which each of the number of sequences is subjected to alignment processing, and acquiring a set of elements capable of discriminating the specific sequence through computational processing on the group of alignment data.
摘要翻译： 提供一种准确有效地获取用于识别的识别元素的候选的方法。 提供了一种在特定序列上获取一组特定元素的方法，用于从多个序列中区分特定序列，包括以下步骤：获取其中每个序列数量经过对准处理的一组对准数据， 以及通过对对齐数据组的计算处理获取能够区分特定序列的一组元素。
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