知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

10 条记录 (耗时 0.014 秒)

    Method of detection and disease state management for renal diseases
    3.
    发明授权
    Method of detection and disease state management for renal diseases 失效
    肾脏疾病的检测和疾病状态管理方法

    公开(公告)号：US07109044B1

    公开(公告)日：2006-09-19

    申请号：US09786503

    申请日：1999-04-09

    申请人： Hiroshi Oda ,  Kosuke Seiki ,  Hiroshi Nakajima ,  Nobuyuki Sato ,  Yoshihiro Urade ,  Nobuhito Hirawa ,  Yoshio Uehara

    发明人： Hiroshi Oda ,  Kosuke Seiki ,  Hiroshi Nakajima ,  Nobuyuki Sato ,  Yoshihiro Urade ,  Nobuhito Hirawa ,  Yoshio Uehara

    IPC分类号： G01N33/53

    CPC分类号： G01N33/6893 ,  G01N33/573 ,  G01N33/70 ,  G01N33/88 ,  G01N2800/347 ,  Y10S436/811

    摘要： The present invention relates to a method of detection of an early-stage renal disease, comprising determining the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample taken from a subject and comparing the determined concentration with a reference value set by determining the concentrations of human lipocalin-type prostaglandin D synthase in body fluid samples taken from healthy subjects; and a method of disease state management for a renal disease, comprising determining the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample taken from a subject and evaluating the glomerular filtration ability of the subject from the determined concentration.

    摘要翻译： 本发明涉及一种早期肾病的检测方法，包括测定取自受试者的体液样品中人脂笼蛋白型前列腺素D合成酶的浓度，并将测定的浓度与通过确定 来自健康受试者的体液样品中人脂笼蛋白型前列腺素D合成酶的浓度; 以及肾病疾病状态管理方法，包括测定取自对象的体液样品中人脂质运载蛋白型前列腺素D合成酶的浓度，并根据测定的浓度评价受试者的肾小球滤过能力。

    Method for predicting pregnancy-induced hypertension
    5.
    发明授权
    Method for predicting pregnancy-induced hypertension 失效
    预测妊娠高血压的方法

    公开(公告)号：US07399596B2

    公开(公告)日：2008-07-15

    申请号：US10573072

    申请日：2004-09-24

    申请人： Hiroshi Oda ,  Kosuke Seiki ,  Yasuhiko Shiina ,  Nobuyuki Sato ,  Satoru Takeda ,  Naomi Eguchi ,  Yoshihiro Urade

    发明人： Hiroshi Oda ,  Kosuke Seiki ,  Yasuhiko Shiina ,  Nobuyuki Sato ,  Satoru Takeda ,  Naomi Eguchi ,  Yoshihiro Urade

    IPC分类号： G01N33/53

    CPC分类号： C12Q1/533 ,  G01N33/689 ,  G01N2800/368

    摘要： Provided are: a method for predicting the onset of pregnancy-induced hypertension (PIH) by precisely detecting abnormalities that occur before the onset of PIH (where such abnormalities have been impossible to detect by various conventional testing methods for PIH) while imposing less of a burden on a subject; a method for evaluating a fetus and placental functions in PIH; and a method for detecting PIH, which comprises measuring the level of human lipocalin-type prostaglandin D synthase (L-PGDS) in a body fluid sample collected from a subject.

    摘要翻译： 提供：通过精确检测在PIH发病之前发生的异常（其中这种异常不可能通过各种常规的PIH检测方法检测）而预测妊娠诱发的高血压（PIH）的发作的方法，同时施加较少的 一个主题的负担; 用于评估PIH中胎儿和胎盘功能的方法; 以及检测PIH的方法，其包括测量从受试者收集的体液样品中的人脂笼蛋白型前列腺素D合成酶（L-PGDS）的水平。