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1.发明授权
公开(公告)号：US4196078A
公开(公告)日：1980-04-01
申请号：US961388
申请日：1978-11-14
申请人： Erich Muller-Spath , Konrad Muller , Heinz Kister , Walter Schurhoff , Friedrich W. Hillnhutter , Walter Laucht
发明人： Erich Muller-Spath , Konrad Muller , Heinz Kister , Walter Schurhoff , Friedrich W. Hillnhutter , Walter Laucht
IPC分类号： B01D21/00 , B01D21/02 , B01D25/00 , B01D29/11 , B01D33/00 , B01D35/00 , B01D36/04 , B03B5/00 , B03B9/04 , C04B5/02 , C21B3/08 , B01D23/24 , B01D37/02
CPC分类号： B01D21/2488 , B01D21/00 , B01D21/0012 , B01D21/02 , B01D21/2461
摘要： Method and apparatus for dewatering granulated material, particularly blast furnace slag that has been granulated by quenching hot slag. The quenched material is dewatered in a bucket wheel whose scoops have perforated bottoms. The solids from the wheel are discharged onto a continuous conveyor; while the liquid is passed along an inclined filter and then clarified and reused. Various filter and clarifier constructions are disclosed.
摘要翻译： 脱颗粒材料的方法和装置，特别是通过淬火热渣造粒的高炉矿渣。 淬火材料在勺子具有穿孔底部的斗轮中脱水。 来自车轮的固体被排出到连续输送机上; 同时液体沿着倾斜的过滤器通过，然后澄清并重复使用。 公开了各种过滤器和澄清器结构。
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2.发明申请公开(公告)号：US20120225793A1
公开(公告)日：2012-09-06
申请号：US13409416
申请日：2012-03-01
申请人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan , John I. Powell , Wyndham Wilson , Elaine Jaffe , Wing C. Chan , Timothy C. Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard I. Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia M. Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zetti , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaloy , Harald Holte , Jan Delabie , T. Andrew Lister
发明人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan , John I. Powell , Wyndham Wilson , Elaine Jaffe , Wing C. Chan , Timothy C. Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard I. Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia M. Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zetti , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaloy , Harald Holte , Jan Delabie , T. Andrew Lister
IPC分类号： C40B30/04
CPC分类号： G01N33/6842 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N2333/51 , G16B25/00 , G16B40/00 , Y02A90/26
摘要： Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
摘要翻译： 基因表达数据为更准确地鉴定和诊断淋巴组织增生性疾病提供了基础。 此外，基因表达数据可用于开发更准确的生存预测因子。 本发明公开了基于基因表达模式鉴定，诊断和预测淋巴瘤或淋巴组织增生性疾病存活的方法。 本发明公开了一种用于从淋巴瘤样品获得基因表达数据的新型微阵列Lymph Dx微阵列。 本发明还公开了多种利用淋巴瘤基因表达数据来确定特定淋巴瘤的身份并预测患有特定淋巴瘤的受试者的存活的方法。 该信息将有助于开发与特定受试者一起使用的治疗方法。
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公开(公告)号：US20120058221A1
公开(公告)日：2012-03-08
申请号：US13266852
申请日：2010-04-28
摘要： A mashing method for producing kvass wort and a method for producing kvass wort concentrate and kvass, where a first portion of mash, in particular a portion of rye mash, is mashed and is heated to a temperature lying below the boiling point (≦90°), a second portion of mash is mashed, and the mixed first and second portions of mash are heated in stages.
摘要翻译： 用于生产麦芽汁的糖化方法和用于生产麦芽汁浓缩物和kvass的方法，其中将醪液的第一部分，特别是黑麦粉糊的一部分捣碎并加热到低于沸点（
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4.发明授权公开(公告)号：US08131475B2
公开(公告)日：2012-03-06
申请号：US11493387
申请日：2006-07-25
申请人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan , John I. Powell , Wyndham Wilson , Elaine Jaffe , Wing C. Chan , Timothy C. Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard I. Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia M Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zettl , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaløy , Harald Holte , Jan Delabie , T. Andrew Lister
发明人： Louis M. Staudt , George Wright , Sandeep Dave , Bruce Tan , John I. Powell , Wyndham Wilson , Elaine Jaffe , Wing C. Chan , Timothy C. Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard I. Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia M Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zettl , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaløy , Harald Holte , Jan Delabie , T. Andrew Lister
CPC分类号： G01N33/6842 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N2333/51 , G06F19/20 , G06F19/24 , Y02A90/26
摘要： Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
摘要翻译： 基因表达数据为更准确地鉴定和诊断淋巴组织增生性疾病提供了基础。 此外，基因表达数据可用于开发更准确的生存预测因子。 本发明公开了基于基因表达模式鉴定，诊断和预测淋巴瘤或淋巴组织增生性疾病存活的方法。 本发明公开了一种用于从淋巴瘤样品获得基因表达数据的新型微阵列Lymph Dx微阵列。 本发明还公开了多种利用淋巴瘤基因表达数据来确定特定淋巴瘤的身份并预测患有特定淋巴瘤的受试者的存活的方法。 该信息将有助于开发与特定受试者一起使用的治疗方法。
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公开(公告)号：US20080108133A1
公开(公告)日：2008-05-08
申请号：US10579290
申请日：2004-11-12
CPC分类号： C07K16/3076 , A61K2039/505 , C07K2317/21 , C07K2317/73 , C07K2317/77
摘要： A purified polypeptide that binds to neoplastic cells, which may be an antibody, is produced by the hybridoma SAM-6, a method for its production and use in the treatment and diagnosis of neoplasms.
摘要翻译： 结合可能是抗体的肿瘤细胞的纯化多肽由杂交瘤SAM-6（其生产和用于治疗和诊断赘生物的方法）产生。
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6.发明申请公开(公告)号：US20070105136A1
公开(公告)日：2007-05-10
申请号：US11493387
申请日：2006-07-25
申请人： Louis Staudt , George Wright , Sandeep Dave , Bruce Tan , John Powell , Wyndham Wilson , Elaine Jaffe , Wing Chan , Timothy Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zettl , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaloy , Harald Holte , Jan Delabie , T. Andrew Lister
发明人： Louis Staudt , George Wright , Sandeep Dave , Bruce Tan , John Powell , Wyndham Wilson , Elaine Jaffe , Wing Chan , Timothy Greiner , Dennis Weisenburger , James Armitage , Kai Fu , Richard Fisher , Lisa Rimsza , Thomas Miller , Thomas Grogan , Elias Campo , Silvia Bea , Itziar Salaverria , Armando Lopez-Guillermo , Emili Montserrat , Victor Moreno , Andreas Zettl , German Ott , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , Julie Vose , Randy Gascoyne , Joseph Connors , Erlend Smeland , Stein Kvaloy , Harald Holte , Jan Delabie , T. Andrew Lister
CPC分类号： G01N33/6842 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N2333/51 , G06F19/20 , G06F19/24 , Y02A90/26
摘要： Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.
摘要翻译： 基因表达数据为更准确地鉴定和诊断淋巴组织增生性疾病提供了基础。 此外，基因表达数据可用于开发更准确的生存预测因子。 本发明公开了基于基因表达模式鉴定，诊断和预测淋巴瘤或淋巴组织增生性疾病存活的方法。 本发明公开了一种用于从淋巴瘤样品获得基因表达数据的新型微阵列Lymph Dx微阵列。 本发明还公开了多种利用淋巴瘤基因表达数据来确定特定淋巴瘤的身份并预测患有特定淋巴瘤的受试者的存活的方法。 该信息将有助于开发与特定受试者一起使用的治疗方法。
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公开(公告)号：US2202117A
公开(公告)日：1940-05-28
申请号：US25989139
申请日：1939-03-04
申请人： KONRAD MULLER
发明人： KONRAD MULLER
CPC分类号： B23Q16/10 , Y10T29/5166 , Y10T74/1418 , Y10T74/1476 , Y10T82/2587
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8.发明申请Anti-Idiotype Antibodies of the Human Monoclonal Antibody Sc-1, and Their Production and Use 失效人单克隆抗体Sc-1的抗独特型抗体及其生产和用途公开(公告)号：US20070269425A1
公开(公告)日：2007-11-22
申请号：US10579147
申请日：2004-11-15
IPC分类号： A61K39/395 , C07K16/42 , C12N5/06 , C12N5/20 , C12P21/00 , C12Q1/04 , G01N33/53 , G01N33/536 , G01N33/559
CPC分类号： C07K16/4266
摘要： The invention features anti-idiotype antibodies of the human monoclonal antibody SC-1, as well as methods for producing and using the anti-idiotype antibodies.
摘要翻译： 本发明涉及人单克隆抗体SC-1的抗独特型抗体，以及用于产生和使用抗独特型抗体的方法。
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公开(公告)号：US1550384A
公开(公告)日：1925-08-18
申请号：US62316723
申请日：1923-03-06
申请人： KONRAD MULLER EUGEN
发明人： KONRAD MULLER EUGEN
IPC分类号： A61N1/04
CPC分类号： A61N1/0456 , A61N1/0492 , A61N1/0496
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公开(公告)号：US20150132297A1
公开(公告)日：2015-05-14
申请号：US14540302
申请日：2014-11-13
申请人： Lisa Rimsza , Andrew T. Lister , Wing C. Chan , Dennis Weisenburger , Jan Delabie , Erlend B. Smeland , Harald Holte , Stein Kvaloy , Rita M. Braziel , Richard I. Fisher , Pedro Jares , Armando Lopez-Guillermo , Elias Campo Guerri , Elaine S. Jaffe , Georg Lenz , Wyndham H. Wilson , George Wright , Sandeep S. Dave , Louis M. Staudt , Randy D. Gascoyne , Joseph M. Connors , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , German Ott
发明人： Lisa Rimsza , Andrew T. Lister , Wing C. Chan , Dennis Weisenburger , Jan Delabie , Erlend B. Smeland , Harald Holte , Stein Kvaloy , Rita M. Braziel , Richard I. Fisher , Pedro Jares , Armando Lopez-Guillermo , Elias Campo Guerri , Elaine S. Jaffe , Georg Lenz , Wyndham H. Wilson , George Wright , Sandeep S. Dave , Louis M. Staudt , Randy D. Gascoyne , Joseph M. Connors , Hans-Konrad Muller-Hermelink , Andreas Rosenwald , German Ott
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , G01N33/57407 , G01N2800/52 , G01N2800/56
摘要： The invention provides methods and materials related to a gene expression-based survival predictor for DLBCL patients.
摘要翻译： 本发明提供了与DLBCL患者的基于表达的生存预测因子相关的方法和材料。
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