公开(公告)号：US06846413B1

公开(公告)日：2005-01-25

申请号：US09509201

申请日：1998-08-28

Applicant: Klaus Kadel ,  Johannes Geser ,  Joachin Eicher ,  Bernhard Freund ,  Stephen Terence Dunne ,  Wulf Bachtler

Inventor： Klaus Kadel ,  Johannes Geser ,  Joachin Eicher ,  Bernhard Freund ,  Stephen Terence Dunne ,  Wulf Bachtler

IPC: B01D29/44 ,  A61M15/00 ,  B01D29/03 ,  B01D39/16 ,  B01D39/20 ,  B01D46/12 ,  B01D46/52 ,  B01D67/00 ,  B01D71/02 ,  B01D24/00

CPC classification number: B01D67/0062 ,  A61M11/00 ,  A61M15/00 ,  A61M2205/0233 ,  B01D39/16 ,  B01D39/2003 ,  B01D39/2027 ,  B01D39/2068 ,  B01D46/0023 ,  B01D46/12 ,  B01D46/40 ,  B01D46/521 ,  B01D67/003 ,  B01D67/0058 ,  B01D67/0069 ,  B01D71/022 ,  B01D2275/206 ,  B01D2325/021 ,  B01D2325/04 ,  B05B15/40

Abstract: A microstructured filter for a fluid, the filter having an inlet for unfiltered fluid and an outlet for filtered fluid, the filter comprising: a plurality of projections (7) which are arranged in at least two rows (3) in mutually juxtaposed relationship and which project out of a base plate (1) and which are an integral component of the base plate, a plurality of passages (8) between the projections (7), and a cover plate which is securable to the base plate to cover the projections (7) and the passages (8), wherein the passages form a plurality of through paths from the inlet to the outlet, said inlet comprises an elongate inlet slot (5) for the unfiltered fluid, which extends over approximately the entire filter width and which is approximately as high as the projection (7) projecting out of the base plate, on the outlet side of the filter. The filter according to the invention remains operational, even if a part of the filter area is obstructed. The filter is used for example in an atomizer with which an aerosol is produced from a fluid which contains a medicament.

Abstract translation: 用于流体的微结构过滤器，所述过滤器具有用于未过滤流体的入口和用于过滤流体的出口，所述过滤器包括：多个突起（7），其以相互并列的关系排列成至少两排（3），并且其中 从基板（1）突出并且其是基板的一体部件，在突起（7）之间的多个通道（8）和可固定到基板以覆盖突起的盖板（ 7）和通道（8），其中通道形成从入口到出口的多个通路，所述入口包括用于未过滤流体的细长入口槽（5），其在大致整个过滤器宽度上延伸，并且 大约等于从过滤器的出口侧伸出基板的突起（7）的高度。 即使过滤器区域的一部分被阻挡，根据本发明的过滤器仍然可操作。 该过滤器用于例如在雾化器中，由含有药物的流体产生气溶胶。

公开(公告)号：US20060078469A1

公开(公告)日：2006-04-13

申请号：US11247584

申请日：2005-10-12

Applicant: Christian Dechant ,  Klaus Kadel ,  Gert Blankenstein

Inventor： Christian Dechant ,  Klaus Kadel ,  Gert Blankenstein

IPC: B01L3/00

CPC classification number: G01N33/48764

Abstract: A device and a plurality of microfluidic platforms for taking up and especially studying or manipulating a sample liquid, a measuring instrument for use with the device and platforms, and a process for performing the studying or manipulating of the sample liquid. Very simple, hygienic and user-friendly handling is enabled in that the platforms which are connected to one another in a sealed state and can each be individually separated and individually, preferably simultaneously, opened for taking up of a sample, such as blood, for, e.g., performing a glucose determination.

Abstract translation: 用于吸收和特别研究或操纵样品液体的装置和多个微流体平台，与装置和平台一起使用的测量仪器以及用于执行对样品液体的研究或操纵的过程。 能够进行非常简单，卫生和用户友好的处理，因为在密封状态下彼此连接的平台可以单独分离并且单独地，优选地同时打开以吸收诸如血液的样品， ，例如进行葡萄糖测定。

公开(公告)号：US07964161B2

公开(公告)日：2011-06-21

申请号：US12292029

申请日：2008-11-10

Applicant: Klaus Kadel ,  Gert Blankenstein

Inventor： Klaus Kadel ,  Gert Blankenstein

IPC: G01N21/00

CPC classification number: F16K99/0017 ,  B01L3/5025 ,  B01L3/502738 ,  B01L3/5085 ,  B01L3/523 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/047 ,  B01L2300/0672 ,  B01L2400/0638 ,  B01L2400/065 ,  F16K99/0001 ,  F16K99/003 ,  F16K99/0034 ,  Y10T436/2575

Abstract: Microstructured device for removable storage of small amounts of liquid with the following features: the device has a carrier; the device has a first cavity with at least one first section for storage of a small amount of liquid; the first section of the first cavity is molded into the carrier; the first section is closed with a cover element and a blocking element; the device has a means for transmission of a force from the cover element to the blocking element which destroys the connection between the blocking element and the carrier or destroys the blocking element itself so that the amount of liquid can be removed from the first section of the cavity.

Abstract translation: 微结构装置可移动存储少量液体，具有以下特点：该装置具有载体; 该装置具有第一腔和至少一个第一部分，用于储存少量液体; 第一腔的第一部分被模制到载体中; 第一部分用盖元件和阻挡元件封闭; 该装置具有用于将力从盖元件传递到阻塞元件的装置，其破坏阻塞元件和载体之间的连接或破坏阻塞元件本身，使得液体的量可从第一部分移除 腔。

公开(公告)号：US20130263847A1

公开(公告)日：2013-10-10

申请号：US13856637

申请日：2013-04-04

Applicant: Klaus KADEL

Inventor： Klaus KADEL

IPC: A61M11/02

CPC classification number: A61M11/02 ,  B81C1/00206 ,  B81C2201/0112 ,  B81C2201/018

Abstract: In a method of producing trench-like depressions (24) in the surface of a wafer (27), particularly a silicon wafer, by plasma etching, in which the depressions (24) are produced by alternate passivation and etching, each depression (24) in its final geometry is provided with a protective layer (30) of the polytetrafluoroethylene type.

Abstract translation: 在通过等离子体蚀刻在晶片（27）表面（特别是硅晶片）的表面中制造沟槽状凹陷（24）的方法中，通过交替的钝化和蚀刻产生凹陷（24），每个凹陷（24 ）在其最终几何形状中设置有聚四氟乙烯类型的保护层（30）。

公开(公告)号：US07815857B2

公开(公告)日：2010-10-19

申请号：US11247584

申请日：2005-10-12

Applicant: Christian Dechant ,  Klaus Kadel ,  Gert Blankenstein

Inventor： Christian Dechant ,  Klaus Kadel ,  Gert Blankenstein

IPC: B01L3/00

CPC classification number: G01N33/48764

Abstract: A device and a plurality of microfluidic platforms for taking up and especially studying or manipulating a sample liquid, a measuring instrument for use with the device and platforms, and a process for performing the studying or manipulating of the sample liquid. Very simple, hygienic and user-friendly handling is enabled in that the platforms which are connected to one another in a sealed state and can each be individually separated and individually, preferably simultaneously, opened for taking up of a sample, such as blood, for, e.g., performing a glucose determination.

Abstract translation: 用于吸收和特别研究或操纵样品液体的装置和多个微流体平台，与装置和平台一起使用的测量仪器以及用于执行对样品液体的研究或操纵的过程。 能够进行非常简单，卫生和用户友好的处理，因为在密封状态下彼此连接的平台可以单独分离并且单独地，优选地同时打开以吸收诸如血液的样品， ，例如进行葡萄糖测定。

公开(公告)号：US20070215723A1

公开(公告)日：2007-09-20

申请号：US11682604

申请日：2007-03-06

Applicant: Achim MOSER ,  Klaus KADEL

Inventor： Achim MOSER ,  Klaus KADEL

IPC: B05B1/34

CPC classification number: B05B1/3436 ,  B05B15/40

Abstract: A simple, compact construction and easy manufacture of a swirl nozzle having a plurality of inlet channels and an outlet channel extending transversely thereto are made possible by the fact that the inlet channels open directly and/or tangentially into the outlet channel. Alternatively or additionally, upstream of the inlet channels is provided a filter structure having smaller flow cross-sections than the inlet channels. The swirl nozzle is used, in particular, for atomizing a liquid medicament formulation. The swirl nozzle is produced from two plate-shaped components, the outlet channel first being etched as a blind bore in one component and then opened up by grinding the component away. Alternatively or additionally, the outlet channel is formed in a different component from the inlet channels.

Abstract translation: 简单紧凑的结构和易于制造具有多个入口通道和横向延伸的出口通道的旋流喷嘴由于入口通道直接和/或切向进入出口通道的事实成为可能。 替代地或另外地，入口通道的上游设置有具有比入口通道更小的流动横截面的过滤器结构。 旋涡喷嘴特别用于雾化液体药物制剂。 涡流喷嘴由两个板状部件制成，出口通道首先被作为盲孔蚀刻在一个部件中，然后通过磨削部件而打开。 或者或另外，出口通道形成在与入口通道不同的部件中。

公开(公告)号：US20050093087A1

公开(公告)日：2005-05-05

申请号：US10948792

申请日：2004-09-24

Applicant: Klaus Kadel ,  Gert Blankenstein

Inventor： Klaus Kadel ,  Gert Blankenstein

IPC: B65D83/00 ,  B01L3/00 ,  F15C5/00 ,  F16K99/00 ,  H01L31/062

CPC classification number: F16K99/0017 ,  B01L3/5025 ,  B01L3/502738 ,  B01L3/5085 ,  B01L3/523 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/047 ,  B01L2300/0672 ,  B01L2400/0638 ,  B01L2400/065 ,  F16K99/0001 ,  F16K99/003 ,  F16K99/0034 ,  Y10T436/2575

Abstract: Microstructured device for removable storage of small amounts of liquid with the following features: the device has a carrier; the device has a first cavity with at least one first section for storage of a small amount of liquid; the first section of the first cavity is molded into the carrier; the first section is closed with a cover element and a blocking element; the device has a means for transmission of a force from the cover element to the blocking element which destroys the connection between the blocking element and the carrier or destroys the blocking element itself so that the amount of liquid can be removed from the first section of the cavity.

Abstract translation: 微结构装置可移动存储少量液体，具有以下特点：该装置具有载体; 该装置具有第一腔和至少一个第一部分，用于储存少量液体; 第一腔的第一部分被模制到载体中; 第一部分用盖元件和阻挡元件封闭; 该装置具有用于将力从盖元件传递到阻塞元件的装置，其破坏阻塞元件和载体之间的连接或破坏阻塞元件本身，使得液体的量可从第一部分移除 腔。

公开(公告)号：US5569855A

公开(公告)日：1996-10-29

申请号：US492833

申请日：1995-06-19

Applicant: Werner Schomburg ,  Richard Rapp ,  Klaus Kadel

Inventor： Werner Schomburg ,  Richard Rapp ,  Klaus Kadel

IPC: F04B43/04 ,  G01L7/08 ,  G01L9/00 ,  G03F7/00 ,  G01L7/00

CPC classification number: F04B43/043 ,  G01L7/082 ,  G01L9/0016 ,  G03F7/00

Abstract: In a method of manufacturing frame-mounted membranes, a first membrane layer is formed on a substrate and openings are formed in this membrane layer which are then covered by a second membrane layer, a frame structure is formed on the membrane layers around the openings and the membrane layers with the frame structure are separated from the substrate to provide the frame-mounted membranes.

Abstract translation: 在框架安装膜的制造方法中，在基板上形成第一膜层，在该膜层上形成开口，然后被第二膜层覆盖，在开口周围的膜层上形成框架结构， 具有框架结构的膜层与衬底分离以提供框架安装的膜。

公开(公告)号：US09220852B2

公开(公告)日：2015-12-29

申请号：US13856637

申请日：2013-04-04

Applicant: Klaus Kadel

Inventor： Klaus Kadel

IPC: A61M11/02 ,  B81C1/00

CPC classification number: A61M11/02 ,  B81C1/00206 ,  B81C2201/0112 ,  B81C2201/018

Abstract: In a method of producing trench-like depressions in the surface of a wafer, particularly a silicon wafer, by plasma etching, in which the depressions are produced by alternate passivation and etching, each depression in its final geometry is provided with a protective layer of the polytetrafluoroethylene type.

Abstract translation: 在通过等离子体蚀刻在晶片表面，特别是硅晶片的表面中产生沟槽状凹陷的方法中，其中通过交替的钝化和蚀刻产生凹陷，其最终几何形状中的每个凹陷设置有保护层 聚四氟乙烯型。

公开(公告)号：US09027854B2

公开(公告)日：2015-05-12

申请号：US11682604

申请日：2007-03-06

Applicant: Achim Moser ,  Klaus Kadel

Inventor： Achim Moser ,  Klaus Kadel

IPC: B05B1/34 ,  B05B15/00

CPC classification number: B05B1/3436 ,  B05B15/40

Abstract: A simple, compact construction and easy manufacture of a swirl nozzle having a plurality of inlet channels and an outlet channel extending transversely thereto are made possible by the fact that the inlet channels open directly and/or tangentially into the outlet channel. Alternatively or additionally, upstream of the inlet channels is provided a filter structure having smaller flow cross-sections than the inlet channels. The swirl nozzle is used, in particular, for atomizing a liquid medicament formulation. The swirl nozzle is produced from two plate-shaped components, the outlet channel first being etched as a blind bore in one component and then opened up by grinding the component away. Alternatively or additionally, the outlet channel is formed in a different component from the inlet channels.

Abstract translation: 简单紧凑的结构和易于制造具有多个入口通道和横向延伸的出口通道的旋流喷嘴由于入口通道直接和/或切向进入出口通道的事实成为可能。 替代地或另外地，入口通道的上游设置有具有比入口通道更小的流动横截面的过滤器结构。 旋涡喷嘴特别用于雾化液体药物制剂。 涡流喷嘴由两个板状部件制成，出口通道首先被作为盲孔蚀刻在一个部件中，然后通过磨削部件而打开。 或者或另外，出口通道形成在与入口通道不同的部件中。