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    Wound dressing and method for controlling severe, life-threatening bleeding
    3.
    发明授权
    Wound dressing and method for controlling severe, life-threatening bleeding 有权
    伤口敷料和控制严重威胁生命的出血的方法

    公开(公告)号：US07482503B2

    公开(公告)日：2009-01-27

    申请号：US10480827

    申请日：2002-06-14

    申请人： Kenton W Gregory ,  Simon McCarthy

    发明人： Kenton W Gregory ,  Simon McCarthy

    IPC分类号： A61F13/00 ,  A61L15/00 ,  A01N43/04

    CPC分类号： A61L15/425 ,  A61F13/00012 ,  A61F13/00034 ,  A61F13/00987 ,  A61F13/00995 ,  A61F13/15203 ,  A61F2013/00106 ,  A61F2013/00463 ,  A61F2013/00468 ,  A61F2013/00472 ,  A61F2013/00536 ,  A61F2013/0054 ,  A61F2013/00931 ,  A61L15/28 ,  A61L2400/04 ,  C08L5/08

    摘要： This invention is directed to advanced hemorrhage control wound dressings, and methods of using a producing same. The subject wound dressing is constructed from a non-mammalian material for control of severe bleeding. The wound dressing is formed of a biomaterial comprising chitosan for controlling severe bleeding. The kind of severe, life-threatening bleeding contemplated by this invention is typically of the type not capable of being stanched when a conventional gauze wound dressing is applied with conventional pressure to the subject wound. The wound dressing being capable of substantially stanching the flow of the severe life-threatening bleeding from the wound by adhering to the wound site, to seal the wound, to accelerate blood clot formation at the wound site, to reinforce clot information at the wound site and prevent bleed out from the wound site, and to substantially prohibit the flow of blood out of the wound site.

    摘要翻译： 本发明涉及先进的出血控制伤口敷料及其制造方法。 受试者伤口敷料由用于控制严重出血的非哺乳动物材料构成。 伤口敷料由包含用于控制严重出血的壳聚糖的生物材料形成。 本发明考虑的严重的威胁生命的出血通常是当将传统的纱布伤口敷料以常规压力施加到受试者伤口时不能被切断的类型。 伤口敷料能够通过粘附到伤口部位上来使伤口的严重危及生命的出血的流动基本上消失，以密封伤口，以加速创伤部位的血块形成，从而在伤口部位加强血块信息 并且防止从伤口部位渗出，并且基本上禁止血液流出伤口部位。

    Myocardial revascularization-optical reflectance catheter and method
    6.
    发明授权
    Myocardial revascularization-optical reflectance catheter and method 失效
    心肌血运重建 - 光反射导管及方法

    公开(公告)号：US06660001B2

    公开(公告)日：2003-12-09

    申请号：US09765968

    申请日：2001-01-19

    申请人： Kenton W. Gregory

    发明人： Kenton W. Gregory

    IPC分类号： A61B1818

    CPC分类号： A61B18/24 ,  A61B18/20 ,  A61B2017/00243 ,  A61B2018/00904

    摘要： A myocardial revascularization device has a catheter suitable for use in a myocardial revascularization procedure, the catheter including an elongate body having a proximal end and a distal end, and tissue-ablating means housed at least partially within the catheter and capable of effectuating tissue ablation adjacent the distal end of the catheter. The device further has an optical reflectance fiber housed within the catheter and coupled to an optical reflectance system. The device is operative to transmit a reflectance signal in the optical reflectance fiber, the reflectance signal including either short optical pulses or low-coherence light. The optical reflectance system is operative to gauge tissue ablation, measure a thickness of tissue adjacent the catheter, and/or determine a position of the distal end relative to adjacent tissue using either of optical time-domain reflectance or optical coherence interferometry.

    摘要翻译： 心肌血运重建装置具有适合用于心肌血运重建术的导管，该导管包括具有近端和远端的细长体，以及至少部分地容纳在导管内并能够实现邻近组织消融的组织消融装置 导管的远端。 该装置还具有容纳在导管内并耦合到光学反射系统的光学反射光纤。 该装置可操作以在光反射光纤中发送反射信号，反射信号包括短光脉冲或低相干光。 光学反射系统用于测量组织消融，测量邻近导管的组织的厚度和/或使用光学时域反射或光学相干干涉测量法来确定远端相对于相邻组织的位置。

    Adherable biomaterial patches and methods for producing and for using same
    7.
    发明授权
    Adherable biomaterial patches and methods for producing and for using same 失效
    可贴附的生物材料贴片及其制造方法和使用方法

    公开(公告)号：US06632450B1

    公开(公告)日：2003-10-14

    申请号：US09859737

    申请日：2001-05-16

    申请人： Kenton W. Gregory

    发明人： Kenton W. Gregory

    IPC分类号： A61F1300

    CPC分类号： A61L31/047 ,  A61F2/0063 ,  A61F2013/00672 ,  A61F2013/00714 ,  A61F2210/0004 ,  A61L24/06 ,  C08L35/04

    摘要： This invention relates to a method for producing an adherable biomaterial patch. The subject patch is capable of being joined onto a tissue substrate. The invention is also directed to the patch per se, and to a method for producing the adherable biomaterial patch which is joined onto a tissue substrate. A preferred patch can even function in a highly acidic environment. The method of the present invention comprises providing a biomaterial patch consisting essentially of elastin or an elastin-based biomaterial having at least one outer surface. Next, at least one outer surface of the biomaterial patch is treated with a selected cyanoacrylate adhesive to produce a adherable biomaterial patch.

    摘要翻译： 本发明涉及一种生产可粘附生物材料贴片的方法。 主题贴片能够连接到组织衬底上。 本发明还涉及贴片本身，以及用于生产连接到组织基底上的可粘附生物材料贴片的方法。 优选的贴剂甚至可以在高度酸性的环境中起作用。 本发明的方法包括提供基本上由弹性蛋白或具有至少一个外表面的基于弹性蛋白的生物材料组成的生物材料贴片。 接下来，用选择的氰基丙烯酸酯粘合剂处理生物材料贴片的至少一个外表面以产生可粘附的生物材料贴片。

    Fluid core laser angioscope
    9.
    发明授权
    Fluid core laser angioscope 失效
    流体核心激光血管镜

    公开(公告)号：US5573531A

    公开(公告)日：1996-11-12

    申请号：US262926

    申请日：1994-06-20

    申请人： Kenton W. Gregory

    发明人： Kenton W. Gregory

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B18/20 ,  A61B18/24 ,  A61B19/00 ,  A61M3/02 ,  A61B17/36

    CPC分类号： A61B18/24 ,  A61B2017/003 ,  A61B2017/22039 ,  A61B2018/206 ,  A61B90/361 ,  A61B90/37 ,  A61M3/0279

    摘要： A liquid core laser optical scope for illuminating, viewing, and delivering laser energy to a site in a lumen of an animal or human body which includes a flexible tube for insertion into the lumen, a conduit housed within the tube, a fluid source for coupling a flow of light transmissive liquid into the conduit, a light source for transmitting visible light through the tube to illuminate the site, an optical fiber bundle having an optical receiving end disposed at the distal end of the optical scope for imaging the illuminated site and transmitting a visible image thereof through the optical scope to an external viewing port, and a fluid core light guide for transmitting laser energy from an energy source into the conduit where the conduit has a sidewall capable of internally reflecting light into the liquid in the conduit so that the liquid waveguides the laser energy through the conduit to the site. The fluid core light guide serves not only to couple laser energy to the site in the lumen but to transmit illumination light to the site and reflected images back to the viewing port.

    摘要翻译： 一种用于照射，观察和传递激光能量到动物或人体的内腔中的部位的液体核心激光光学镜片，其包括用于插入内腔的柔性管，容纳在管内的导管，用于联接的流体源 将透光液体流入导管内的光源，用于透过可见光照射该场所的光源，具有光学接收端的光纤束，该光纤接收端设置在光学镜的远端成像照明部位并透射 通过光学镜片将其可视图像传送到外部观察端口，以及流体芯光导，用于将激光能量从能量源传输到导管中，其中导管具有能够将光内部反射到管道中的液体的侧壁，使得 液体通过导管将激光能量波导到现场。 流体芯光导体不仅用于将激光能量耦合到管腔中的位置，而且将照明光传输到现场并将反射的图像传送回观察端口。