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1.发明申请APPARATUS AND METHODS FOR INTEGRATED SAMPLE PREPARATION, REACTION AND DETECTION 有权集成样品制备，反应和检测的装置和方法公开(公告)号：US20110236960A1
公开(公告)日：2011-09-29
申请号：US13033129
申请日：2011-02-23
Applicant: Dylan Hilmer BIRD , Jesus CHING , Bruce A. JOHNSON , Keith E. MORAVICK , Bruce RICHARDSON
Inventor： Dylan Hilmer BIRD , Jesus CHING , Bruce A. JOHNSON , Keith E. MORAVICK , Bruce RICHARDSON
CPC classification number: B01L7/52 , B01F5/12 , B01F11/0071 , B01F15/0203 , B01F15/0237 , B01F2015/0221 , B01F2215/0037 , B01L3/502 , B01L3/502715 , B01L3/50851 , B01L3/523 , B01L3/527 , B01L7/00 , B01L2200/025 , B01L2200/026 , B01L2200/028 , B01L2200/0647 , B01L2200/10 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/0627 , B01L2300/0654 , B01L2300/0672 , B01L2300/0829 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2400/0406 , B01L2400/043 , B01L2400/0478 , B01L2400/0481 , B01L2400/0622 , B01L2400/0633 , B01L2400/0644 , B01L2400/0683 , C12Q1/6806 , C12Q1/686 , G01N1/38 , G01N35/1079 , G01N2035/0436 , Y10T436/118339 , Y10T436/25375 , Y10T436/255
Abstract: Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non-nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.
Abstract translation: 提供用于分离生物样品的柱和样品上的下游生物测定。 在一个实施方案中，从生物样品中分离核酸样品，并且例如通过聚合酶链式反应扩增核酸样品。 本文提供的盒还可用于分离非核酸样品，例如蛋白质，并对蛋白质进行下游反应，例如结合测定。 还提供了用于进行下游生物测定和检测测定结果的仪器。
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Patent Agency Ranking
2.发明申请Apparatus and Methods for Integrated Sample PReparation, Reaction and Detection 审中-公开综合样本检测，反应和检测的装置和方法公开(公告)号：US20130266948A1
公开(公告)日：2013-10-10
申请号：US13759557
申请日：2013-02-05
Applicant: Dylan Hilmer Bird , Jesus Ching , Bruce A. Johnson , Keith E. Moravick , Bruce Richardson
Inventor： Dylan Hilmer Bird , Jesus Ching , Bruce A. Johnson , Keith E. Moravick , Bruce Richardson
IPC: C12Q1/68
CPC classification number: B01L7/52 , B01F5/12 , B01F11/0071 , B01F15/0203 , B01F15/0237 , B01F2015/0221 , B01F2215/0037 , B01L3/502 , B01L3/502715 , B01L3/50851 , B01L3/523 , B01L3/527 , B01L7/00 , B01L2200/025 , B01L2200/026 , B01L2200/028 , B01L2200/0647 , B01L2200/10 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/0627 , B01L2300/0654 , B01L2300/0672 , B01L2300/0829 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2400/0406 , B01L2400/043 , B01L2400/0478 , B01L2400/0481 , B01L2400/0622 , B01L2400/0633 , B01L2400/0644 , B01L2400/0683 , C12Q1/6806 , C12Q1/686 , G01N1/38 , G01N35/1079 , G01N2035/0436 , Y10T436/118339 , Y10T436/25375 , Y10T436/255
Abstract: Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided, as are methods for using such cartridges. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non-nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.
Abstract translation: 还提供了用于分离生物样品和样品上的下游生物测定的柱，以及使用这种盒的方法。 在一个实施方案中，从生物样品中分离核酸样品，并且例如通过聚合酶链式反应扩增核酸样品。 本文提供的盒还可用于分离非核酸样品，例如蛋白质，并对蛋白质进行下游反应，例如结合测定。 还提供了用于进行下游生物测定和检测测定结果的仪器。
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3.发明授权Apparatus and methods for integrated sample preparation, reaction and detection 有权综合样品制备，反应和检测的装置和方法公开(公告)号：US08372340B2
公开(公告)日：2013-02-12
申请号：US13033129
申请日：2011-02-23
Applicant: Dylan Hilmer Bird , Jesus Ching , Bruce A. Johnson , Keith E. Moravick , Bruce Richardson
Inventor： Dylan Hilmer Bird , Jesus Ching , Bruce A. Johnson , Keith E. Moravick , Bruce Richardson
IPC: B01J19/00
CPC classification number: B01L7/52 , B01F5/12 , B01F11/0071 , B01F15/0203 , B01F15/0237 , B01F2015/0221 , B01F2215/0037 , B01L3/502 , B01L3/502715 , B01L3/50851 , B01L3/523 , B01L3/527 , B01L7/00 , B01L2200/025 , B01L2200/026 , B01L2200/028 , B01L2200/0647 , B01L2200/10 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/0627 , B01L2300/0654 , B01L2300/0672 , B01L2300/0829 , B01L2300/0867 , B01L2300/087 , B01L2300/1805 , B01L2400/0406 , B01L2400/043 , B01L2400/0478 , B01L2400/0481 , B01L2400/0622 , B01L2400/0633 , B01L2400/0644 , B01L2400/0683 , C12Q1/6806 , C12Q1/686 , G01N1/38 , G01N35/1079 , G01N2035/0436 , Y10T436/118339 , Y10T436/25375 , Y10T436/255
Abstract: Cartridges for the isolation of a biological sample and downstream biological assays on the sample are provided. In one embodiment, a nucleic acid sample is isolated from a biological sample and the nucleic acid sample is amplified, for example by the polymerase chain reaction. The cartridges provided herein can also be used for the isolation of non-nucleic acid samples, for example proteins, and to perform downstream reactions on the proteins, for example, binding assays. Instruments for carrying out the downstream biological assays and for detecting the results of the assays are also provided.
Abstract translation: 提供用于分离生物样品的柱和样品上的下游生物测定。 在一个实施方案中，从生物样品中分离核酸样品，并且例如通过聚合酶链式反应扩增核酸样品。 本文提供的盒还可用于分离非核酸样品，例如蛋白质，并对蛋白质进行下游反应，例如结合测定。 还提供了用于进行下游生物测定和检测测定结果的仪器。
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4.发明申请Laser Capture Microdissection (LCM) Extraction Device and Device Carrier, and Method for Post-LCM Fluid Processing 有权激光捕获显微解剖（LCM）提取装置和装置载体以及后LCM流体处理方法公开(公告)号：US20110059548A1
公开(公告)日：2011-03-10
申请号：US12856182
申请日：2010-08-13
Applicant: Thomas M. Baer , Robert H. Reamey , Keith E. Moravick , David F. Head , Bruce J. Richardson , Derrick A. Richardson
Inventor： Thomas M. Baer , Robert H. Reamey , Keith E. Moravick , David F. Head , Bruce J. Richardson , Derrick A. Richardson
CPC classification number: G01N1/30 , G01N1/2813 , G01N1/40 , G01N2001/284 , Y10T436/25375 , Y10T436/255
Abstract: The present invention generally discloses an extraction system that provides a locale for fluid processing and extraction on a post-microcapture transfer film. The extraction system includes a transfer film carrier and an extraction device forming a reservoir. The extraction system selectively excludes regions of the transfer film from the reservoir to advantageously reduce contamination due to matter adhered to the transfer film by non-specific transfer.
Abstract translation: 本发明通常公开了一种提取系统，其提供用于后微量捕获转移膜上的流体处理和萃取的区域。 提取系统包括转印膜载体和形成储存器的提取装置。 提取系统选择性地从储存器排除转印膜的区域，以有利地减少由于通过非特异性转移附着在转印膜上的物质引起的污染。
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公开(公告)号：US09103757B2
公开(公告)日：2015-08-11
申请号：US12856182
申请日：2010-08-13
Applicant: Thomas M. Baer , Robert H. Reamey , Keith E. Moravick , David F. Head , Bruce J. Richardson , Derrick A. Richardson
Inventor： Thomas M. Baer , Robert H. Reamey , Keith E. Moravick , David F. Head , Bruce J. Richardson , Derrick A. Richardson
CPC classification number: G01N1/30 , G01N1/2813 , G01N1/40 , G01N2001/284 , Y10T436/25375 , Y10T436/255
Abstract: The present invention generally discloses an extraction system that provides a locale for fluid processing and extraction on a post-microcapture transfer film. The extraction system includes a transfer film carrier and an extraction device forming a reservoir. The extraction system selectively excludes regions of the transfer film from the reservoir to advantageously reduce contamination due to matter adhered to the transfer film by non-specific transfer.
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6.发明授权Laser capture microdissection (LCM) extraction device and device carrier, and method for post-LCM fluid processing 有权激光捕获显微解剖（LCM）提取装置和装置载体，以及后LCM流体处理方法公开(公告)号：US07776273B2
公开(公告)日：2010-08-17
申请号：US09844187
申请日：2001-04-26
Applicant: Thomas M. Baer , Robert H. Reamey , Keith E. Moravick , David F. Head , Bruce J. Richardson , Derrick A. Richardson
Inventor： Thomas M. Baer , Robert H. Reamey , Keith E. Moravick , David F. Head , Bruce J. Richardson , Derrick A. Richardson
IPC: B01L3/00
CPC classification number: G01N1/30 , G01N1/2813 , G01N1/40 , G01N2001/284 , Y10T436/25375 , Y10T436/255
Abstract: The present invention generally discloses an extraction system that provides a locale for fluid processing and extraction on a post-microcapture transfer film. The extraction system includes a transfer film carrier and an extraction device forming a reservoir. The extraction system selectively excludes regions of the transfer film from the reservoir to advantageously reduce contamination due to matter adhered to the transfer film by non-specific transfer.
Abstract translation: 本发明通常公开了一种提取系统，其提供用于后微量捕获转移膜上的流体处理和萃取的区域。 提取系统包括转印膜载体和形成储存器的提取装置。 提取系统选择性地从储存器排除转印膜的区域，以有利地减少由于通过非特异性转移附着在转印膜上的物质引起的污染。
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