Adhesive applicator tips with improved flow properties
    2.
    发明授权
    Adhesive applicator tips with improved flow properties 有权
    具有改善流动性能的粘合剂涂抹器尖端

    公开(公告)号:US06428234B1

    公开(公告)日:2002-08-06

    申请号:US09672035

    申请日:2000-09-29

    CPC classification number: A61B17/00491 B05C17/002

    Abstract: An article of manufacture for dispensing an adhesive material, such as a synthetic or semi-synthetic polymerizable or cross-linkable monomer material, includes a container body, and a porous applicator tip having a proximal end that is attached to the container body, and a distal end located away from the container body, wherein the adhesive material is located in the container body in a non-contacting relationship with the applicator tip prior to dispensing the material. A flow pattern of the adhesive material within or on the applicator tip is controlled by providing one or more cuts in the applicator tip to alter flow properties of the adhesive material through the applicator tip.

    Abstract translation: 用于分配诸如合成或半合成可聚合或可交联单体材料的粘合剂材料的制品包括容器主体和具有附接到容器主体的近端的多孔施用器末端,以及 远端远离容器主体,其中粘合剂材料在分配材料之前以与施用器尖端非接触的关系位于容器主体中。 通过在施用器尖端中提供一个或多个切口来控制通过施用器尖端的粘合剂材料的流动性质来控制施加器尖端内部或之上的粘合剂材料的流动图案。

    Composite Bone Graft Substitute Cement and Articles Produced Therefrom
    3.
    发明申请
    Composite Bone Graft Substitute Cement and Articles Produced Therefrom 有权
    复合骨移植替代水泥及其制品

    公开(公告)号:US20070178171A1

    公开(公告)日:2007-08-02

    申请号:US11674537

    申请日:2007-02-13

    Abstract: The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a β-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.

    Abstract translation: 本发明提供一种适于在与水溶液混合时形成骨移植物替代水泥的颗粒组合物,包括i)具有约5至约20微米的双峰颗粒分布和中值粒度的硫酸钙半水合物粉末,其中所述钙 硫酸盐半水合物以基于颗粒组合物的总重量的至少约70重量%的浓度存在; ii)一水合一磷酸钙粉末; 和iii)中值粒度小于约20微米的β-磷酸三钙粉末。 还提供了由其制成的骨移植替代物水泥,包含颗粒组合物的骨移植替代试剂盒,制备和使用颗粒组合物的方法,以及由骨移植物替代水泥制成的制品。

    Composite bone graft substitute cement and articles produced therefrom
    4.
    发明申请
    Composite bone graft substitute cement and articles produced therefrom 有权
    复合骨移植替代水泥及其制品

    公开(公告)号:US20070059281A1

    公开(公告)日:2007-03-15

    申请号:US11530085

    申请日:2006-09-08

    Abstract: The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a β-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.

    Abstract translation: 本发明提供一种适于在与水溶液混合时形成骨移植物替代水泥的颗粒组合物,包括i)具有约5至约20微米的双峰颗粒分布和中值粒度的硫酸钙半水合物粉末,其中所述钙 硫酸盐半水合物以基于颗粒组合物的总重量的至少约70重量%的浓度存在; ii)一水合一磷酸钙粉末; 和iii)中值粒度小于约20微米的β-磷酸三钙粉末。 还提供了由其制成的骨移植替代物水泥,包含颗粒组合物的骨移植替代试剂盒,制备和使用颗粒组合物的方法,以及由骨移植物替代水泥制成的制品。

    Thermoplastic copolymer of tetrafluoroethylene and perfluoromethyl vinyl ether and medical devices employing the copolymer

    公开(公告)号:US20060041091A1

    公开(公告)日:2006-02-23

    申请号:US11227658

    申请日:2005-09-14

    CPC classification number: C08F214/18

    Abstract: An improved elastomeric material is described comprising an essentially noncross-linkable amorphous copolymer of tetrafluoroethylene (TFE) and perfluoromethyl vinyl ether (PMVE) which is both a thermoplastic and exhibits exceptional mechanical properties. This material is particularly suitable for use in ultra-clean environments, and particularly for use in an implantable device, since it does not contain contaminants that previous thermoset TFE/PMVE copolymers have required. Among the improved properties of the present invention are excellent biocompatibility, high matrix tensile strength, high clarity, high abrasion resistance, high purity, adequate elasticity, and ease of processing due to the thermoplastic, and noncross-linkable structure of the copolymer. The material of the present invention is also a high strength bonding agent particularly suited for bonding porous PTFE to itself or to other porous substances at room or elevated temperatures.

    Bone graft substitute composition
    6.
    发明申请
    Bone graft substitute composition 有权
    骨移植替代物组成

    公开(公告)号:US20080031917A1

    公开(公告)日:2008-02-07

    申请号:US11872564

    申请日:2007-10-15

    Abstract: Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first mixture having calcium sulfate hemihydrate and a plasticizing material to form a second mixture; waiting a predetermined period of time after forming said second mixture; and then contacting demineralized bone with the second mixture to form the composition. A composition can be formed from a kit including a first mixture having calcium sulfate hemihydrate and a plasticizing substance, a second mixture having demineralized bone, and a mixing solution. The first and second mixtures and the mixing solution are unblended.

    Abstract translation: 公开了骨移植替代物组合物和制备组合物的方法。 在一些实施方案中,制备组合物的方法包括使混合溶液与具有硫酸钙半水合物和增塑材料的第一混合物接触以形成第二混合物; 在形成所述第二混合物之后等待预定的时间段; 然后使软化骨与第二混合物接触以形成组合物。 组合物可以由试剂盒形成,所述试剂盒包括具有硫酸钙半水合物和增塑物质的第一混合物,具有软化骨的第二混合物和混合溶液。 第一和第二混合物和混合溶液是未共混的。

    Composite Bone Graft Substitute Cement and Articles Produced Therefrom

    公开(公告)号:US20070128248A1

    公开(公告)日:2007-06-07

    申请号:US11624460

    申请日:2007-01-18

    Abstract: The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a β-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.

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