公开(公告)号：US20200254258A1

公开(公告)日：2020-08-13

申请号：US16862200

申请日：2020-04-29

Applicant: Jose A. Parodi Amaya ,  Edward F. Austin ,  Jin-Woo Choi

Inventor： Jose A. Parodi Amaya ,  Edward F. Austin ,  Jin-Woo Choi

IPC: A61N1/36 ,  A61N1/04 ,  A61N1/378 ,  A61N1/05

Abstract: Methods and apparatus are disclosed relating to the stimulating of tissue including nerve tissue based on combinations of capacitors and resistors. Application and removal of voltage to an electrical circuit is taught as part of a method of creating voltage waveforms for nerve and other tissue with such waveforms creating neural signals.

公开(公告)号：US20110189195A1

公开(公告)日：2011-08-04

申请号：US13059006

申请日：2008-08-18

Applicant: Sunghoon Kim ,  Jin Woo Choi

Inventor： Sunghoon Kim ,  Jin Woo Choi

IPC: A61K39/395 ,  C12N5/09 ,  C12N15/63 ,  C07K16/40 ,  A61K31/7088 ,  C12Q1/00 ,  C12Q1/68 ,  A61P35/00 ,  A61P35/04

CPC classification number: A61K31/7088 ,  A61K48/00 ,  C12N9/93 ,  C12N15/1137 ,  C12N2310/11 ,  C12N2310/14 ,  C12Y601/01006 ,  G01N33/5017

Abstract: The present invention relates to a novel function of lysyl tRNA synthetase (KRS) which enhances tumor cell migration and affects cancer metastasis via KRS's interaction with laminin receptor (67LR) by its translocation to membrane. More particularly, the present invention relates to a method for modulating cancer metastasis or migration, which comprises regulating intracellular levels of KRS; a composition for preventing or treating cancer; use of expression vector for inhibiting the expression of KRS; a method for preventing or treating cancer; use of an agent for inhibiting an activity of KRS; a method for screening an agent which modulates cancer metastasis or migration; and a method for screening an agent which inhibits the interaction of KRS with 67LR, by said novel function. Thus, KRS can modulate cancer metastasis or migration and furthermore, can modulate intra-cellular metabolism related to 67LR. The interaction between KRS and 67LR can be used effectively in treating, preventing and/or diagnosing of various diseases or disorders related to the interaction.

Abstract translation: 本发明涉及赖氨酰tRNA合成酶（KRS）的新功能，其通过Kis与层粘连蛋白受体（67LR）的相互作用通过其迁移到膜来增强肿瘤细胞迁移并影响癌症转移。 更具体地，本发明涉及一种调节癌症转移或迁移的方法，其包括调节细胞内KRS水平; 用于预防或治疗癌症的组合物; 使用表达载体抑制KRS的表达; 预防或治疗癌症的方法; 使用抑制KRS活性的药剂; 筛选调节癌症转移或迁移的药物的方法; 以及通过所述新功能筛选抑制KRS与67LR的相互作用的药剂的方法。 因此，KRS可以调节癌症转移或迁移，此外，可以调节与67LR相关的细胞内代谢。 KRS和67LR之间的相互作用可以有效地用于治疗，预防和/或诊断与相互作用相关的各种疾病或病症。

公开(公告)号：US20100008487A1

公开(公告)日：2010-01-14

申请号：US12499418

申请日：2009-07-08

Applicant: Ho-Jung AHN ,  Jin-Woo CHOI ,  Dong-Seok JUNG

Inventor： Ho-Jung AHN ,  Jin-Woo CHOI ,  Dong-Seok JUNG

IPC: H04M3/42

CPC classification number: H04M3/38 ,  H04M2207/18 ,  H04W8/183 ,  H04W48/18

Abstract: An apparatus and a method for blocking a specific network in a mobile communication terminal are provided. The method includes adding a first network to a blocked network list, when the first network is the only network available to provide service to a terminal, temporarily removing the first network from the blocked network list and temporarily receiving service from the first network. Thus, the user does not have to pay roaming fees in the unwanted network, suffer from undesired communication quality, or use unwanted additional functions.

Abstract translation: 提供了一种用于阻止移动通信终端中的特定网络的装置和方法。 该方法包括将第一网络添加到阻塞的网络列表中，当第一网络是可用于向终端提供服务的唯一网络时，暂时从阻止的网络列表中移除第一网络并从第一网络临时接收服务。 因此，用户不必在不想要的网络中支付漫游费，遭受不期望的通信质量或使用不需要的附加功能。

公开(公告)号：US07480275B2

公开(公告)日：2009-01-20

申请号：US10262102

申请日：2002-09-30

Applicant: Hi-Chan Moon ,  Jin-Woo Choi ,  Young-Ky Kim ,  Jae-Min Ahn ,  Hyun-Suk Lee

Inventor： Hi-Chan Moon ,  Jin-Woo Choi ,  Young-Ky Kim ,  Jae-Min Ahn ,  Hyun-Suk Lee

IPC: H04B7/216

CPC classification number: H04W52/14 ,  H04B1/707 ,  H04W52/08 ,  H04W52/146 ,  H04W52/322 ,  H04W52/325 ,  H04W52/44 ,  H04W52/50 ,  H04W52/54 ,  H04W52/58

Abstract: A common power control channel transmission device for a base station in a CDMA communication system is provided having a selector for receiving power control commands to be transmitted to multiple subscribers and multiplexing the received power control commands; and a spreading modulator for spreading an output of the selector by multiplying the output of the selector by a spreading sequence. The common power control channel transmission device can be used to control power of a reverse link common channel. For the power control of the reverse link common channel, the base station receives a signal from a mobile station via the reverse link common channel, and transmits to the mobile station a power control command for controlling a transmission power of the reverse link common channel according to a measured strength of the received signal.

Abstract translation: 提供了一种用于CDMA通信系统中的基站的公共功率控制信道传输设备，具有用于接收要发送给多个用户的功率控制命令并对接收到的功率控制命令进行多路复用的选择器; 以及扩展调制器，用于通过将选择器的输出乘以扩展序列来扩展选择器的输出。 公共功率控制信道传输设备可用于控制反向链路公共信道的功率。 对于反向链路公共信道的功率控制，基站经由反向链路公共信道从移动台接收信号，并向移动台发送用于控制反向链路公共信道的发送功率的功率控制指令， 到接收信号的测量强度。

公开(公告)号：US06724740B1

公开(公告)日：2004-04-20

申请号：US09132404

申请日：1998-08-11

Applicant: Jin-Woo Choi ,  Soon-Young Yoon ,  Jae-Min Ahn ,  Young-Ky Kim ,  Joong-Ho Jeong

Inventor： Jin-Woo Choi ,  Soon-Young Yoon ,  Jae-Min Ahn ,  Young-Ky Kim ,  Joong-Ho Jeong

IPC: H04J1300

CPC classification number: H04W48/12 ,  H04B1/707 ,  H04B7/264 ,  H04W52/0216 ,  H04W88/08 ,  Y02D70/25 ,  Y02D70/40 ,  Y02D70/449

Abstract: A CDMA communication system transmitting/receiving control information during a voice and/or data communication service by using a dedicated control channel. A message frame length for the control information is variable according to an amount of the control information. The CDMA communication system includes a base station device and a terminal device. The base station device has a forward pilot channel generator for generating a pilot signal, a forward dedicated control channel generator for generating a control message for a forward dedicated control channel, a forward fundamental channel generator for generating a voice signal, and a forward supplemental channel generator for generating packet data. The terminal device has a terminal device including, a reverse dedicated control channel generator for generating a control message for a reverse dedicated control channel, a reverse pilot channel generator for generating a pilot signal by adding a power control signal to the pilot signal, a reverse fundamental channel generator for generating a voice signal, and a reverse supplemental channel generator for generating packet data.

Abstract translation: CDMA通信系统通过使用专用控制信道在语音和/或数据通信服务期间发送/接收控制信息。 控制信息的消息帧长度根据控制信息的量而变化。 CDMA通信系统包括基站装置和终端装置。 基站装置具有用于产生导频信号的前向导频信道发生器，用于产生用于前向专用控制信道的控制消息的前向专用控制信道发生器，用于生成语音信号的前向基本信道发生器，以及前向补充信道 发生器用于生成分组数据。 终端装置具有：终端装置，包括用于产生用于反向专用控制信道的控制消息的反向专用控制信道发生器，用于通过向导频信号添加功率控制信号来产生导频信号的反向导频信道发生器，反向 用于产生语音信号的基本信道发生器，以及用于生成分组数据的反向辅助信道发生器。

公开(公告)号：US09511085B2

公开(公告)日：2016-12-06

申请号：US13059006

申请日：2008-08-18

Applicant: Sunghoon Kim ,  Jin Woo Choi

Inventor： Sunghoon Kim ,  Jin Woo Choi

IPC: C07K16/30 ,  C12N15/113 ,  A61K38/17 ,  A61K39/395 ,  A61K31/7088 ,  C12N9/00 ,  G01N33/50 ,  A61K48/00

CPC classification number: A61K31/7088 ,  A61K48/00 ,  C12N9/93 ,  C12N15/1137 ,  C12N2310/11 ,  C12N2310/14 ,  C12Y601/01006 ,  G01N33/5017

Abstract: The present invention relates to a novel function of lysyl tRNA synthetase (KRS) which enhances tumor cell migration and affects cancer metastasis via KRS's interaction with laminin receptor (67LR) by its translocation to membrane. More particularly, the present invention relates to a method for modulating cancer metastasis or migration, which comprises regulating intracellular levels of KRS; a composition for preventing or treating cancer; use of expression vector for inhibiting the expression of KRS; a method for preventing or treating cancer; use of an agent for inhibiting an activity of KRS; a method for screening an agent which modulates cancer metastasis or migration; and a method for screening an agent which inhibits the interaction of KRS with 67LR, by said novel function. Thus, KRS can modulate cancer metastasis or migration and furthermore, can modulate intracellular metabolism related to 67LR. The interaction between KRS and 67LR can be used effectively in treating, preventing and/or diagnosing of various diseases or disorders related to the interaction.

Abstract translation: 本发明涉及赖氨酰tRNA合成酶（KRS）的新功能，其通过Kis与层粘连蛋白受体（67LR）的相互作用通过其迁移到膜来增强肿瘤细胞迁移并影响癌症转移。 更具体地，本发明涉及一种调节癌症转移或迁移的方法，其包括调节细胞内KRS水平; 用于预防或治疗癌症的组合物; 使用表达载体抑制KRS的表达; 预防或治疗癌症的方法; 使用抑制KRS活性的药剂; 筛选调节癌症转移或迁移的药物的方法; 以及通过所述新功能筛选抑制KRS与67LR的相互作用的药剂的方法。 因此，KRS可以调节癌症转移或迁移，此外，可以调节与67LR相关的细胞内代谢。 KRS和67LR之间的相互作用可以有效地用于治疗，预防和/或诊断与相互作用相关的各种疾病或病症。

公开(公告)号：US20110311623A1

公开(公告)日：2011-12-22

申请号：US12671981

申请日：2008-03-12

Applicant: Mikyoung Hahn ,  Jin-Woo Choi ,  Dae-Hyeon Kim

Inventor： Mikyoung Hahn ,  Jin-Woo Choi ,  Dae-Hyeon Kim

IPC: A61K9/28 ,  A61K31/166 ,  A61K9/14

CPC classification number: A61K31/166 ,  A61K9/0056 ,  A61K9/1676 ,  A61K9/2081 ,  A61K9/5026 ,  A61K9/5047 ,  A61K9/5078 ,  A61K31/192 ,  A61K31/4184 ,  A61K31/454 ,  A61K31/519 ,  A61K31/5375

Abstract: The present invention relates to a composition for manufacturing an orally disintegrating dosage form that is used to prevent a coating layer of an active substance which is formed in a predetermined size in order to mask a bitter taste or an unpleasant taste. A predetermined ratio of an excipient having lower hardness than the coated active substance and another excipient having higher hardness and larger particle size than the active substance are used as means for protecting the coating layer from being destroyed.

Abstract translation: 本发明涉及一种用于制造口腔崩解剂型的组合物，其用于防止以预定尺寸形成的活性物质的涂层以掩盖苦味或不愉快的味道。 使用具有比涂覆的活性物质低的硬度的赋形剂和具有比活性物质更高的硬度和更大的粒径的另外的赋形剂的预定比例作为保护涂层不被破坏的手段。

公开(公告)号：US08021982B2

公开(公告)日：2011-09-20

申请号：US12563459

申请日：2009-09-21

Applicant: Oh-Jung Kwon ,  Anthony G. Domenicucci ,  O Sung Kwon ,  Jin-Woo Choi

Inventor： Oh-Jung Kwon ,  Anthony G. Domenicucci ,  O Sung Kwon ,  Jin-Woo Choi

IPC: H01L21/44

CPC classification number: H01L21/28518 ,  C23C14/18 ,  C23C14/5806 ,  H01L21/2855

Abstract: A method is provided for forming a metal semiconductor alloy that includes providing a deposition apparatus that includes a platinum source and a nickel source, wherein the platinum source is separate from the nickel source; positioning a substrate having a semiconductor surface in the deposition apparatus; forming a metal alloy on the semiconductor surface, wherein forming the metal alloy comprises a deposition stage in which the platinum source deposits platinum to the semiconductor surface at an initial rate at an initial period that is greater than a final rate at a final period of the deposition stage, and the nickel source deposits nickel to the semiconductor surface; and annealing the metal alloy to react the nickel and platinum with the semiconductor substrate to provide a nickel platinum semiconductor alloy.

Abstract translation: 提供一种用于形成金属半导体合金的方法，其包括提供包括铂源和镍源的沉积设备，其中所述铂源与所述镍源分离; 将具有半导体表面的基板定位在沉积设备中; 在半导体表面上形成金属合金，其中形成金属合金包括沉积阶段，其中铂源以最初的速率以最初的速率将铂沉积到半导体表面上，该初始时间段大于最终时间段的最终时间 沉积阶段，镍源将镍沉积到半导体表面; 并退火金属合金以使镍和铂与半导体衬底反应以提供镍铂半导体合金。

公开(公告)号：US20100029072A1

公开(公告)日：2010-02-04

申请号：US12507887

申请日：2009-07-23

Applicant: Jae-Eon Park ,  Jun-Keun Kwak ,  Jin-Woo Choi ,  Sunfei Fang ,  Jiang Yan

Inventor： Jae-Eon Park ,  Jun-Keun Kwak ,  Jin-Woo Choi ,  Sunfei Fang ,  Jiang Yan

IPC: H01L21/768 ,  H01L21/8234

CPC classification number: H01L21/823475 ,  H01L21/76828 ,  H01L21/76831 ,  H01L21/823425

Abstract: Methods of forming integrated circuit devices include forming an electrically insulating layer having a contact hole therein, on a substrate, and then depositing an electrically insulating liner onto a sidewall of the contact hole using an atomic layer deposition (ALD) technique. This electrically insulating liner, which may include gelatinous silica or silicon dioxide, for example, may be deposited to a thickness in a range from 40 Å to 100 Å. A portion of the electrically insulating liner is then removed from a bottom of the contact hole and a barrier metal layer is then formed on the electrically insulating liner and on a bottom of the contact hole. The step of forming the barrier metal layer may be followed by filling the contact hole with a metal interconnect.

Abstract translation: 形成集成电路器件的方法包括在衬底上形成其中具有接触孔的电绝缘层，然后使用原子层沉积（ALD）技术将电绝缘衬垫沉积到接触孔的侧壁上。 例如，可以包括凝胶状二氧化硅或二氧化硅的这种电绝缘衬垫可以沉积到从而在一个范围内的厚度。 然后从接触孔的底部去除电绝缘衬垫的一部分，然后在电绝缘衬垫上和接触孔的底部上形成阻挡金属层。 形成阻挡金属层的步骤之后可以用金属互连填充接触孔。

公开(公告)号：US06831910B1

公开(公告)日：2004-12-14

申请号：US09274830

申请日：1999-03-23

Applicant: Hi-Chan Moon ,  Jin-Woo Choi ,  Young-Ky Kim ,  Jae-Min Ahn ,  Hyun-Suk Lee

Inventor： Hi-Chan Moon ,  Jin-Woo Choi ,  Young-Ky Kim ,  Jae-Min Ahn ,  Hyun-Suk Lee

IPC: H04B7216

CPC classification number: H04W52/14 ,  H04B1/707 ,  H04W52/08 ,  H04W52/146 ,  H04W52/322 ,  H04W52/325 ,  H04W52/44 ,  H04W52/50 ,  H04W52/54 ,  H04W52/58

Abstract: A common power control channel transmission device for a base station in a CDMA communication system is provided having a selector for receiving power control commands to be transmitted to multiple subscribers and multiplexing the received power control commands; and a spreading modulator for spreading an output of the selector by multiplying the output of the selector by a spreading sequence. The common power control channel transmission device can be used to control power of a reverse link common channel. For the power control of the reverse link common channel, the base station receives a signal from a mobile station via the reverse link common channel, and transmits to the mobile station a power control command for controlling a transmission power of the reverse link common channel according to a measured strength of the received signal.

Abstract translation: 提供了一种用于CDMA通信系统中的基站的公共功率控制信道传输设备，具有用于接收要发送给多个用户的功率控制命令并对接收到的功率控制命令进行多路复用的选择器; 以及扩展调制器，用于通过将选择器的输出乘以扩展序列来扩展选择器的输出。 公共功率控制信道传输设备可用于控制反向链路公共信道的功率。 对于反向链路公共信道的功率控制，基站经由反向链路公共信道从移动台接收信号，并向移动台发送用于控制反向链路公共信道的发送功率的功率控制指令， 到接收信号的测量强度。