公开(公告)号：US07867329B2

公开(公告)日：2011-01-11

申请号：US11895232

申请日：2007-08-23

Applicant: Leif Hermansson ,  Jesper Lööf ,  Håkan Engqvist

Inventor： Leif Hermansson ,  Jesper Lööf ,  Håkan Engqvist

IPC: C04B7/32

CPC classification number: C04B28/06 ,  A61K6/0008 ,  A61K6/0091 ,  A61K6/0631 ,  A61K6/0675 ,  A61L24/02 ,  C04B2111/00836 ,  C04B14/043 ,  C04B20/008 ,  C04B22/124 ,  C04B22/126 ,  C04B24/06 ,  C04B24/2641 ,  C04B2103/0086 ,  A61K6/0835 ,  C08L33/08 ,  C08L69/00

Abstract: A dental cement system, including an aqueous hydration liquid and a powdered material that essentially consists of an inorganic cement system, which powdered material has the capacity to form a complex, chemically bonded material with inorganic as well as organic phases with properties suitable for cementation of implant to another implant and/or to tooth or bone tissue.

Abstract translation: 一种牙科水泥系统，包括水性水合液体和基本上由无机水泥体系组成的粉末材料，该粉末材料具有与无机和有机相形成复合化学键合的材料的能力，其特性适合于粘合 植入到另一植入物和/或牙齿或骨组织。

公开(公告)号：US20120189987A1

公开(公告)日：2012-07-26

申请号：US13499449

申请日：2009-10-09

Applicant: Leif Hermansson ,  Jesper Lööf ,  Adam Faris

Inventor： Leif Hermansson ,  Jesper Lööf ,  Adam Faris

IPC: A61C5/11 ,  A61K6/00 ,  B32B37/14 ,  A61K6/083

CPC classification number: A61L27/446 ,  A61K6/0205 ,  A61K6/0835 ,  A61L24/0089 ,  A61L27/10 ,  C04B28/06 ,  C04B2111/00836 ,  C04B7/02 ,  C04B14/22 ,  C04B20/008 ,  C04B22/124 ,  C04B24/04 ,  C04B24/2641

Abstract: The present invention generally relates to chemically bonded ceramic biomaterials, preferably a dental material or an implant material, comprising two binder systems. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and, optionally, minor amounts of calcium silicate. The second binder system is a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste forming the biomaterial. The biomaterial also comprises inert filler particles. The inventive biomaterial is free from reactive glass and thus provides for a simplified two binder systems biomaterial with a reduced number of required reactive components The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic biomaterial, and a paste from which the biomaterial is formed, as well as a kit comprising the powdered composition and hydration liquid, as well as methods and use of the biomaterial in dental and implant applications.

Abstract translation: 本发明通常涉及化学结合的陶瓷生物材料，优选牙科材料或植入材料，其包含两种粘合剂体系。 主要的粘合剂体系在其水合时形成化学键合的陶瓷，并且包括粉末状的铝酸钙和任选地少量的硅酸钙。 第二粘合剂系统是交联的有机粘合剂体系，其提供形成生物材料的新混合糊料的初始交联。 生物材料还包括惰性填料颗粒。 本发明的生物材料不含活性玻璃，因此提供了一种具有减少数量的所需反应性组分的简化的两种粘合剂体系生物材料。本发明涉及用于制备本发明化学键合的陶瓷生物材料的粉末组合物，以及生物材料 形成，以及包含粉末状组合物和水合液体的试剂盒，以及生物材料在牙齿和植入物应用中的方法和用途。

公开(公告)号：US20120189983A1

公开(公告)日：2012-07-26

申请号：US13499359

申请日：2009-10-02

Applicant: Leif Hermansson ,  Jesper Lööf ,  Per-Olof Glantz ,  Emil Abrahamsson

Inventor： Leif Hermansson ,  Jesper Lööf ,  Per-Olof Glantz ,  Emil Abrahamsson

IPC: A61C8/00 ,  B05D3/00 ,  A61K6/06

CPC classification number: A61C8/0006 ,  A61C8/0013 ,  A61K6/0612 ,  A61K6/0637 ,  A61L27/30 ,  C04B28/06 ,  C04B41/009 ,  C04B41/508 ,  C04B41/85 ,  C04B2111/00215 ,  C04B2111/00836 ,  C04B7/02 ,  C04B14/22 ,  C04B22/0053 ,  C04B22/124 ,  C04B2103/0086 ,  C04B14/30 ,  C04B24/06 ,  C04B35/10 ,  C04B35/00 ,  C04B35/48

Abstract: The present invention relates to a calcium aluminate based paste forming a chemically bonded biomaterial on hydration thereof for in vivo anchoring of new implants, or stabilizing of existing implants in situ to an adjacent bone tissue, which paste provides a controlled pH value and temperature as well as initial hardening time. By virtue of the pH value and temperature the paste exhibits antibacterial and/or bacteriostatic properties. The present invention also relates to a method of preparing implants to be implanted wherein the implant is coated with the paste, a method of implanting a coated implant, as well as methods of preventing and treating implant related conditions, such as periimplantitis, and a kit for preparing the paste. The invention is especially intended for re-stabilization of dental implants, and implantation into low quality bone tissue.

Abstract translation: 本发明涉及一种在其水化时形成化学键合的生物材料的铝酸钙基糊料，用于体内锚定新植入物，或将现有植入物原位稳定到相邻骨组织，该糊剂还提供受控的pH值和温度 作为初始硬化时间。 由于pH值和温度，糊状物具有抗细菌和/或抑菌特性。 本发明还涉及一种制备待植入的植入物的方法，其中所述植入物涂覆有所述浆料，植入涂覆的植入物的方法，以及预防和治疗植入物相关病症（例如周边炎）和试剂盒 用于制备糊状物。 本发明特别用于牙科植入物的再稳定化和植入低品质骨组织中。