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1.发明授权Dibenzoyl peroxide derivatives, preparation method thereof and cosmetic or dermatological compositions containing same 有权二苯甲酰基过氧化物衍生物，其制备方法和含有它们的化妆品或皮肤病学组合物公开(公告)号：US08901357B2
公开(公告)日：2014-12-02
申请号：US13519871
申请日：2010-12-22
Applicant: Nicolas Rodeville , Jean-Claude Pascal , Claire Bouix-Peter
Inventor： Nicolas Rodeville , Jean-Claude Pascal , Claire Bouix-Peter
IPC: C07C409/32 , A61K31/075 , C07C409/34
CPC classification number: C07C409/34 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/74
Abstract: The use of compounds in the treatment of skin disorders is described. In particular, compounds having the general formula (I): are described. A process for preparing such compounds and their cosmetic or dermatological use are also described.The described compounds can act as bactericides. As a result, they can be useful in the treatment of conditions associated with the presence of bacteria, more specifically of P. acnes.
Abstract translation: 描述了化合物在治疗皮肤病中的用途。 特别地，描述了具有通式（I）的化合物。 还描述了制备这些化合物及其化妆品或皮肤病学用途的方法。 所述的化合物可以作为杀菌剂。 因此，它们可用于治疗与细菌存在相关的病症，特别是痤疮丙酸杆菌。
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2.发明授权Derivatives of novel peroxides, method of preparation thereof and use thereof in human medicine as well as in cosmetics for the treatment or prevention of acne 有权新型过氧化物的衍生物，其制备方法及其在人类医学中的应用以及用于治疗或预防痤疮的化妆品公开(公告)号：US08729312B2
公开(公告)日：2014-05-20
申请号：US13514262
申请日：2010-12-10
Applicant: Claire Bouix-Peter , Jean-Claude Pascal , Nicolas Rodeville
Inventor： Claire Bouix-Peter , Jean-Claude Pascal , Nicolas Rodeville
IPC: C07C409/00
CPC classification number: C07C409/34 , A61K8/38 , A61K8/42 , A61Q19/00 , C07C409/40
Abstract: Compounds of the following general formula (I): are described. Also described, are methods of preparing the compounds and their use in therapeutics.
Abstract translation: 描述以下通式（I）的化合物。 还描述了制备化合物及其在治疗中的用途的方法。
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3.发明申请NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS 有权新型苯并噻二唑化合物，其合成方法及其在医药中的用途如同化妆品公开(公告)号：US20120323006A1
公开(公告)日：2012-12-20
申请号：US13381234
申请日：2010-06-28
Applicant: Laurence Clary , Sandrine Chambon , Laurent Chantalat , Carine Rosignoli , Olivier Roye , Jean-Claude Pascal , Marlene Schuppli
Inventor： Laurence Clary , Sandrine Chambon , Laurent Chantalat , Carine Rosignoli , Olivier Roye , Jean-Claude Pascal , Marlene Schuppli
IPC: C07D295/26 , C07D471/04 , C07D413/12 , C07D401/12 , C07D403/12
CPC classification number: C07D215/14 , A61K31/4965 , A61K31/497 , A61K31/551 , C07D209/10 , C07D209/12 , C07D209/20 , C07D209/24 , C07D209/26 , C07D213/30 , C07D213/55 , C07D213/56 , C07D213/68 , C07D261/20 , C07D295/15 , C07D295/26 , C07D471/04 , Y02A50/411
Abstract: Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
Abstract translation: 描述具有式（I）结构的苯磺酰胺化合物。 还描述了用于合成化合物的方法及其在人或兽医学药物组合物和化妆品组合物中的用途。
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4.发明申请OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREON IN HUMAN MEDICINE AND IN COSMETICS 有权OXOAZE衍生物，其制备方法及其在人体药物和化妆品中的应用公开(公告)号：US20110274638A1
公开(公告)日：2011-11-10
申请号：US13127643
申请日：2009-11-04
Applicant: Claire Bouix-Peter , Itaru Suzuki , Nicolas Rodeville , Pascale Mauvais , Jean-Claude Pascal
Inventor： Claire Bouix-Peter , Itaru Suzuki , Nicolas Rodeville , Pascale Mauvais , Jean-Claude Pascal
IPC: A61K8/49 , A61K31/397 , A61Q9/00 , A61Q19/08 , A61P17/00 , A61Q19/02 , A61Q19/00 , A61P17/10 , A61P19/02 , A61P3/00 , A61P15/10 , A61P25/00 , A61P25/22 , A61P31/04 , A61P31/12 , A61P25/16 , A61P35/04 , A61P29/00 , A61P11/06 , C07D403/12
CPC classification number: C07D403/12 , A61K8/4906 , A61K8/494 , A61K31/4178 , A61K2800/78 , A61Q5/10 , A61Q17/04 , A61Q19/004 , A61Q19/007 , A61Q19/008 , A61Q19/02 , A61Q19/04 , C07D401/12 , Y02A50/463
Abstract: Compounds derived from oxoazetidine corresponding to general formula (I) compositions containing same, processes for their preparation and their use in pharmaceutical or cosmetic compositions are described.
Abstract translation: 描述了衍生自对应于通式（I）的含氮氮杂环丁烷的化合物，其含有它们的组合物，其制备方法及其在药物或化妆品组合物中的应用。
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5.发明申请NOVEL PHENYLBORONIC ACID COMPOUNDS AND INTERMEDIATES AND PROCESSES FOR THE PREPARATION THEREOF 审中-公开新型苯硼酸化合物及其制备方法及其制备方法公开(公告)号：US20100145105A1
公开(公告)日：2010-06-10
申请号：US12635255
申请日：2009-12-10
Applicant: Eric Terranova , Jean-Claude Pascal
Inventor： Eric Terranova , Jean-Claude Pascal
IPC: C07C43/205
Abstract: Vitamin D derivatives, notably non-steroidal vitamin D derivatives, are prepared from novel disubstituted phenylboronic acid compounds having the formula (I): and also from the novel intermediates having the formulae (1), (2), (3) and (10):
Abstract translation: 维生素D衍生物，特别是非甾体维生素D衍生物，由具有式（I）的新型二取代苯基硼酸化合物制备：以及具有式（1），（2），（3）和（10）的新型中间体 ）：
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Patent Agency Ranking
6.发明申请公开(公告)号：US20100087669A1
公开(公告)日：2010-04-08
申请号：US12635299
申请日：2009-12-10
Applicant: Eric TERRANOVA , Jean-Claude Pascal
Inventor： Eric TERRANOVA , Jean-Claude Pascal
Abstract: Vitamin D derivatives, notably non-steroidal vitamin D derivatives, are prepared from novel disubstituted phenylboronic acid compounds having the formula (I): and also from the novel intermediates having the formulae (1), (2), (3) and (10):
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![Novel method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid](/abs-image/US/2008/04/17/US20080091045A1/abs.jpg.150x150.jpg)
7.发明申请Novel method for the preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid 有权用于制备6- [3-（1-金刚烷基）-4-甲氧基苯基] -2-萘甲酸的新方法公开(公告)号：US20080091045A1
公开(公告)日：2008-04-17
申请号：US11905955
申请日：2007-10-05
Applicant: Eric Terranova , Jean-Claude Pascal
Inventor： Eric Terranova , Jean-Claude Pascal
IPC: C07C51/367
CPC classification number: C07C51/367 , C07C65/24
Abstract: A novel method for preparing 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid includes a Suzuki reaction between 3-adamantyl-4-methoxyphenylboronic acid of formula (II): and 6-bromo-2-naphthoic acid of formula (III):
Abstract translation: 制备6- [3-（1-金刚烷基）-4-甲氧基苯基] -2-萘甲酸的新方法包括式（II）的3-金刚烷基-4-甲氧基苯基硼酸与6-溴-2 式（III）的萘甲酸：
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8.发明授权Oxoazetidine derivatives, process for the preparation thereof and use thereon in human medicine and in cosmetics 有权氧氮杂环丁啶衍生物，其制备方法及其在人类药物和化妆品中的用途公开(公告)号：US08871187B2
公开(公告)日：2014-10-28
申请号：US13127643
申请日：2009-11-04
Applicant: Claire Bouix-Peter , Itaru Suzuki , Nicolas Rodeville , Pascale Mauvais , Jean-Claude Pascal
Inventor： Claire Bouix-Peter , Itaru Suzuki , Nicolas Rodeville , Pascale Mauvais , Jean-Claude Pascal
IPC: A61K31/4178 , C07D403/12 , C07D401/12 , A61Q5/10 , A61Q17/04 , A61Q19/00 , A61Q19/04 , A61Q19/02 , A61K8/49
CPC classification number: C07D403/12 , A61K8/4906 , A61K8/494 , A61K31/4178 , A61K2800/78 , A61Q5/10 , A61Q17/04 , A61Q19/004 , A61Q19/007 , A61Q19/008 , A61Q19/02 , A61Q19/04 , C07D401/12 , Y02A50/463
Abstract: Compounds derived from oxoazetidine corresponding to general formula (I) compositions containing same, processes for their preparation and their use in pharmaceutical or cosmetic compositions are described.
Abstract translation: 描述了衍生自对应于通式（I）的含氮氮杂环丁烷的化合物，其含有它们的组合物，其制备方法及其在药物或化妆品组合物中的应用。
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![Preparation of 3-[5′-(3,4-bis(hydroxymethyl)benzyloxy)-2′-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol](/abs-image/US/2009/12/29/US07638657B2/abs.jpg.150x150.jpg)
9.发明授权Preparation of 3-[5′-(3,4-bis(hydroxymethyl)benzyloxy)-2′-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol 失效制备3- [5' - （3,4-双（羟甲基）苄氧基）-2'-乙基-2-丙基联苯-4-基]戊-3-醇公开(公告)号：US07638657B2
公开(公告)日：2009-12-29
申请号：US11802029
申请日：2007-05-18
Applicant: Eric Terranova , Sebastien Daver , Christine Marty , Jean-Claude Pascal
Inventor： Eric Terranova , Sebastien Daver , Christine Marty , Jean-Claude Pascal
CPC classification number: C07C41/26 , C07C37/20 , C07C39/12 , C07C45/673 , C07C45/71 , C07C49/83 , C07C49/84 , C07C43/23
Abstract: 3-[5′-(3,4-bis(hydroxymethyl)benzyloxy)-2′-ethyl-2-propylbiphenyl-4-yl]pentan-3-ol is prepared from the novel intermediate, 6-ethyl-4′-(1-ethyl-1-hydroxypropyl)-2′-propylbiphenyl-3-ol.
Abstract translation: 由新型中间体6-乙基-4'-氧代-3,4-二氢吡啶制备3- [5' - （3,4-双（羟甲基）苄氧基）-2'-乙基-2-丙基联苯-4-基]戊-3-醇， （1-乙基-1-羟丙基）-2'-丙基联苯-3-醇。
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10.发明授权Peroxide derivatives, their process of preparation and their use in human medicine and in cosmetics for the treatment or prevention of acne 有权过氧化物衍生物，其制备方法及其在人类医学和化妆品中的用途，用于治疗或预防痤疮公开(公告)号：US09102607B2
公开(公告)日：2015-08-11
申请号：US13514579
申请日：2010-12-10
Applicant: Claire Bouix-Peter , Jean-Claude Pascal , Nicolas Rodeville
Inventor： Claire Bouix-Peter , Jean-Claude Pascal , Nicolas Rodeville
IPC: A61K31/075 , C07C69/035 , C07C409/34 , A61K8/38 , A61K8/42 , A61Q19/00 , C07C409/40
CPC classification number: C07C409/34 , A61K8/38 , A61K8/42 , A61Q19/00 , C07C409/40 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/74
Abstract: Compounds of the following general formula (I): are described. Also described, are processes of their preparation and their use in therapeutic applications.
Abstract translation: 描述以下通式（I）的化合物。 还描述了它们的制备方法及其在治疗应用中的用途。
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