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公开(公告)号：US09060742B2
公开(公告)日：2015-06-23
申请号：US12728082
申请日：2010-03-19
申请人： Mark Brister , Paul V. Neale , James Brauker
发明人： Mark Brister , Paul V. Neale , James Brauker
IPC分类号： A61B5/1486 , A61B5/1473 , A61B5/05 , A61B5/1495 , A61B5/00 , A61B5/145 , A61B5/15
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0004 , A61B5/05 , A61B5/14 , A61B5/1411 , A61B5/145 , A61B5/14503 , A61B5/14507 , A61B5/14514 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/6801 , A61B5/6832 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/72 , A61B17/3468 , A61B2017/3492 , A61B2560/0223 , A61B2560/045 , A61M5/14 , A61M5/14244 , A61M5/1723 , A61M2005/1585 , G06F19/00 , Y02A90/26
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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公开(公告)号：US08858434B2
公开(公告)日：2014-10-14
申请号：US11077739
申请日：2005-03-10
IPC分类号： A61B5/145 , A61B5/1468 , A61B5/00 , A61B5/1486 , A61B5/05 , A61B5/1495 , A61B5/15
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0004 , A61B5/05 , A61B5/14 , A61B5/1411 , A61B5/145 , A61B5/14503 , A61B5/14507 , A61B5/14514 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/6801 , A61B5/6832 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/72 , A61B17/3468 , A61B2017/3492 , A61B2560/0223 , A61B2560/045 , A61M5/14 , A61M5/14244 , A61M5/1723 , A61M2005/1585 , G06F19/00 , Y02A90/26
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
摘要翻译： 本发明一般涉及用于测量宿主中分析物的系统和方法。 更具体地说，本发明涉及用于经皮测量宿主中的葡萄糖的系统和方法。
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公开(公告)号：US08285354B2
公开(公告)日：2012-10-09
申请号：US12730077
申请日：2010-03-23
IPC分类号： A61B5/05
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/14542 , A61B5/14865 , A61B2560/0223 , G06F19/00
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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公开(公告)号：US07959569B2
公开(公告)日：2011-06-14
申请号：US12730144
申请日：2010-03-23
IPC分类号： A61B5/00
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/14542 , A61B5/14865 , A61B2560/0223 , G06F19/00
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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公开(公告)号：US07933639B2
公开(公告)日：2011-04-26
申请号：US12730058
申请日：2010-03-23
IPC分类号： A61B5/05
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/14542 , A61B5/14865 , A61B2560/0223 , G06F19/00
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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公开(公告)号：US07925321B2
公开(公告)日：2011-04-12
申请号：US12730123
申请日：2010-03-23
IPC分类号： A61B5/05
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/14542 , A61B5/14865 , A61B2560/0223 , G06F19/00
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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公开(公告)号：US07857760B2
公开(公告)日：2010-12-28
申请号：US11360819
申请日：2006-02-22
申请人： Mark Brister , James Brauker , J. Michael Dobbles
发明人： Mark Brister , James Brauker , J. Michael Dobbles
IPC分类号： A61B5/00
CPC分类号： A61B5/1451 , A61B5/0031 , A61B5/14517 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/1495 , A61B5/6832 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/7264 , A61B5/742 , A61B2560/0223 , A61B2560/0276 , A61B2560/028 , A61L2/12 , A61L2/206 , G06F19/00 , Y02A90/22 , Y02A90/26 , Y10T29/49004
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
摘要翻译： 本发明一般涉及用于测量宿主中分析物的系统和方法。 更具体地说，本发明涉及用于经皮测量宿主中的葡萄糖的系统和方法。
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公开(公告)号：US20080194935A1
公开(公告)日：2008-08-14
申请号：US12101790
申请日：2008-04-11
申请人： Mark Brister , Paul V. Neale , James Brauker
发明人： Mark Brister , Paul V. Neale , James Brauker
IPC分类号： A61B5/05
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0004 , A61B5/05 , A61B5/14 , A61B5/1411 , A61B5/145 , A61B5/14503 , A61B5/14507 , A61B5/14514 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/6801 , A61B5/6832 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/72 , A61B17/3468 , A61B2017/3492 , A61B2560/0223 , A61B2560/045 , A61M5/14 , A61M5/14244 , A61M5/1723 , A61M2005/1585 , G06F19/00 , Y02A90/26
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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9.发明申请Systems and methods for replacing signal artifacts in a glucose sensor data stream 有权用于替换葡萄糖传感器数据流中的信号伪影的系统和方法公开(公告)号：US20070032706A1
公开(公告)日：2007-02-08
申请号：US11498410
申请日：2006-08-02
申请人： Apurv Kamath , James Brauker , Aarthi Mahalingam , Ying Li
发明人： Apurv Kamath , James Brauker , Aarthi Mahalingam , Ying Li
IPC分类号： A61B5/00
CPC分类号： A61B5/7203 , A61B5/01 , A61B5/145 , A61B5/14532 , A61B5/14539 , A61B5/14542 , A61B5/14865 , A61B5/6848 , A61B5/7225 , A61B5/7239 , A61B5/7257 , A61B5/726 , A61B5/742 , A61B2560/0252 , G06F19/00 , Y02A90/26
摘要： Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as interfering species, ischemia, pH changes, temperatures changes, known or unknown sources of mechanical, electrical and/or biochemical noise, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system processes some or the entire data stream continually or intermittently based at least in part on whether the signal artifact event has occurred.
摘要翻译： 用于最小化或消除由于非葡萄糖速率限制现象（例如干扰物质，缺血，pH变化，温度变化，已知或未知的机械，电和/或生化噪声来源）引起的瞬时非葡萄糖相关信号噪声的系统和方法，以及 类似。 系统监测来自葡萄糖传感器的数据流，并检测具有比电子或扩散相关系统噪声更高的幅度的信号伪像。 该系统至少部分地基于信号伪影事件是否已经发生，连续或间歇地处理一些或整个数据流。
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公开(公告)号：US20070027370A1
公开(公告)日：2007-02-01
申请号：US11503367
申请日：2006-08-10
申请人： James Brauker , Robert Boock , Monica Rixman , Peter Simpson , Mark Brister
发明人： James Brauker , Robert Boock , Monica Rixman , Peter Simpson , Mark Brister
IPC分类号： A61B5/00
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1473 , A61B5/411 , A61B5/418 , A61B5/6848 , A61B2562/08 , C12Q1/006 , G01N33/54366 , G01N33/66 , Y02A50/55 , Y02A50/58
摘要： Biointerface membranes are provided which can be utilized with implantable devices, such as devices for the detection of analyte concentrations in a biological sample. More particularly, methods for monitoring glucose levels in a biological fluid sample using an implantable analyte detection device incorporating such membranes are provided.
摘要翻译： 提供生物界面膜，其可以与可植入装置一起使用，例如用于检测生物样品中分析物浓度的装置。 更具体地，提供了使用包含这种膜的可植入分析物检测装置监测生物流体样品中的葡萄糖水平的方法。
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