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    STACKING DEVICE FOR MICROTITER PLATES
    2.
    发明申请
    STACKING DEVICE FOR MICROTITER PLATES 有权

    公开(公告)号：US20220411210A1

    公开(公告)日：2022-12-29

    申请号：US17847403

    申请日：2022-06-23

    Applicant: INTEGRA Biosciences AG

    Inventor： Andreas Städler ,  Hans-Jürgen Tiedtke

    IPC: B65G59/06 ,  G01N35/02

    Abstract: A device for receiving, stacking, and removing microplates is presented and described. The device comprises a tower for stacking the microplates, wherein a microplate comprises a container and, optionally, a lid. There is a retaining device at the lower end of the tower, which has a first retaining tool and a second retaining tool, and preferably partially encompasses a microplate. The first retaining tool is designed to hold a microplate in a form-fitting manner. The second retaining tool is designed to fix a container in the microplate in place in a frictional manner. The first retaining tool is above the second retaining tool in the stacking direction. A system that comprises the device described above, a dispenser device, and a transport device, is also disclosed. The dispenser device is used to fill microplates, and the transport device is used to add and remove microplates to and from the device.

    Ejection Mechanism for Pipette Tips
    4.
    发明申请
    Ejection Mechanism for Pipette Tips 审中-公开

    公开(公告)号：US20170197205A1

    公开(公告)日：2017-07-13

    申请号：US15402278

    申请日：2017-01-10

    Applicant: Integra Biosciences AG

    Inventor： Adrian Fetz ,  Noel Pasquier

    IPC: B01L3/02

    CPC classification number: B01L3/0237 ,  B01L3/0279 ,  B01L2200/04 ,  B01L2200/08 ,  B01L2300/023 ,  B01L2300/024 ,  B01L2300/027 ,  G01N2035/103

    Abstract: The invention pertains to a handheld pipette (11) with a handle (13), an interconnecting part (15) to attach a pipette tip and an ejection mechanism to remove the pipette tip from the interconnecting part (15). The ejection mechanism has a movable slider (43) relative to the interconnecting part (15) in the area of the interconnecting part (15 that is designed to slide the pipette tip from the interconnection part (15) when operating the ejection mechanism. The pipette (11) furthermore possesses a first and a second operating element (45, 47) accessible from the outside to operate the ejection mechanism, whereby the first operating element (45) is arranged in the area of the handle (13) and is operable by hand, and where the second operating element (47) is intended to be operated by an external device (71).

    Volume Adjustment for Manual Pipettor
    5.
    发明申请
    Volume Adjustment for Manual Pipettor 有权
    手动移纸器的音量调节

    公开(公告)号：US20160303557A1

    公开(公告)日：2016-10-20

    申请号：US15075377

    申请日：2016-03-21

    Applicant: Integra Biosciences AG

    Inventor： Christopher P. LaCroix

    IPC: B01L3/02

    CPC classification number: B01L3/0224 ,  B01L2200/0605 ,  B01L2200/087 ,  B01L2300/026 ,  B01L2400/0478

    Abstract: A manual pipette includes a manual volume adjustment having three discreet resolutions. The pipette uses three rotatable step cylinders and one non-rotatable cylinder to set the overall stroke length for the piston. The step cylinders are rotated by manual dials that are accessible on either side of the pipette body. The dial bodies include numerical scales corresponding to the setting of the respective step cylinders.

    Abstract translation: 手动移液器包括具有三个谨慎分辨率的手动音量调节。 移液管使用三个可旋转的步进气缸和一个不可旋转的气缸来设定活塞的总行程长度。 步进气瓶通过手动拨盘旋转，可在移液管主体的两侧进入。 表盘主体包括对应于相应台阶滚筒的设置的数字刻度。

    PIPETTE TIPS AND RACK SYSTEM FOR LIQUID HANDLING EQUIPMENT
    6.
    发明公开
    PIPETTE TIPS AND RACK SYSTEM FOR LIQUID HANDLING EQUIPMENT 审中-公开

    公开(公告)号：US20240307884A1

    公开(公告)日：2024-09-19

    申请号：US18601382

    申请日：2024-03-11

    Applicant: Integra Biosciences AG

    Inventor： Christoph Mauracher ,  Terrence Kelly ,  Kyle R. DelloRusso ,  Lukas Wielatt ,  Noel Pasquier

    IPC: B01L9/00

    CPC classification number: B01L9/543

    Abstract: A pipette tip rack system includes a disposable refill pack and a reusable base. After use, the disposable refill pack can be disassembled, and the components can be stacked or nested for space saving storage prior to disposal or recycling. The pipette tips in the disposable refill pack are configured to fit on a mounting shaft that includes outwardly circumferentially extending locking lobes over which the pipette tip collar is mounted. The pipette tip includes a circular cantilever sealing ring that seals laterally against the mounting shaft when the tip is fully mounted. The circular cantilever sealing ring has an annular wall surrounded by a gap. The annular wall has an inside surface that slants inward to provide a lateral interference fit with the mounting shaft. The annular wall bends radially outward towards the gap, rather than stretching, when the tip is mounted on the mounting shaft thereby reducing require insertion force. The refill pack can be made with less plastic because of the reduced cumulative insertion forces, even when loading 384 pipette tips simultaneously in an automated liquid handling system.

    Sample and reagent containers with anti-vacuum feature
    8.
    发明授权
    Sample and reagent containers with anti-vacuum feature 有权

    公开(公告)号：US11033903B2

    公开(公告)日：2021-06-15

    申请号：US16002624

    申请日：2018-06-07

    Applicant: Integra Biosciences AG

    Inventor： Terrence Kelly ,  Jonathan Harkins ,  George Kalmakis ,  Gary Nelson

    IPC: B01L3/00 ,  B01L3/02

    Abstract: Pipetting containers, such as reservoirs, reservoir liners, microplates, PCR plates, microtubes and PCR tubes, include anti-vacuum channels on the bottom wall of the receptacle to prevent a pipette tip vacuum engaging the wall during aspiration. The groupings of anti-vacuum channels are located on the bottom surface facing upward into the basin that holds liquid samples or reagents. The anti-vacuum channels also lower the required working volume for pipetting and reduce liquid waste.

    Multi-channel pipettor with repositionable tips
    9.
    发明授权
    Multi-channel pipettor with repositionable tips 有权
    多通道移液器具有可重新定位的提示

    公开(公告)号：US09339810B2

    公开(公告)日：2016-05-17

    申请号：US13952726

    申请日：2013-07-29

    Applicant: Integra Biosciences AG

    Inventor： David Earl Butz ,  Gregory Mathus ,  Richard Cote ,  George P. Kalmakis

    IPC: B01L3/02

    CPC classification number: B01L3/0237 ,  B01L3/0227 ,  B01L2200/022 ,  B01L2300/0829

    Abstract: A hand-held, multi-channel pipettor has an electronically controlled motor to reposition pipette tips for different center to center spacing. Each repositionable tip fitting assembly has a cam following pin that is driven by cam tracks in a motor driven roller drum. Stationary ports for the multiple aspiration cylinders are strategically placed to simplify management of flexible tubes leading to the repositionable pipette tip fitting assemblies. The pipettor has a user interface that can be operated conveniently by one hand to reposition pipette tips. It has a pipette tip ejection mechanism with a sinusoidal stripper bar.

    Abstract translation: 手持式多通道移液器具有电子控制电机，用于重新定位不同中心间距的吸头。 每个可重新定位的尖端配件组件具有凸轮跟随销，该凸轮跟随销由马达驱动滚筒中的凸轮轨道驱动。 用于多个抽吸气瓶的固定端口有策略地放置，以简化导向可重新定位的移液管尖端配件组件的柔性管的管理。 移液器具有可以用一只手方便地操作以重新定位移液器吸头的用户界面。 它具有带有正弦剥离器条的移液管尖端喷射机构。

    Locking pipette tip and mounting shaft in hand-held manual pipette
    10.
    发明授权
    Locking pipette tip and mounting shaft in hand-held manual pipette 有权
    将移液器吸头和安装轴锁定在手持式手动移液器中

    公开(公告)号：US09333500B2

    公开(公告)日：2016-05-10

    申请号：US14524685

    申请日：2014-10-27

    Applicant: Integra Biosciences AG

    Inventor： Gregory Mathus ,  Terrance Kelly ,  Richard Cote

    IPC: B01L3/02

    CPC classification number: B01L3/0217 ,  B01L3/0275 ,  B01L3/0279 ,  B01L2200/023 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/087 ,  B01L2300/027 ,  Y10T137/0318 ,  Y10T436/2575

    Abstract: The pipetting method is directed to mounting and ejecting a disposable pipette tip. The pipetting system has one or more tip mounting shafts with an upper locking section and a lower sealing section. The upper locking section has outwardly extending lobes spaced around the mounting shaft and located above a stop member. The lower sealing section on the tip mounting shaft is located below the stop. As the mounting shaft is inserted into the collar of the disposable pipette, the collar distorts out of round and engages the lobes on the upper locking section of the tip mounting shaft. Contemporaneously, the lower sealing section of the mounting shaft seals against the barrel of the disposable pipette tip.

    Abstract translation: 移液方法涉及安装和喷射一次性吸头。 移液系统具有一个或多个具有上部锁定部分和下部密封部分的尖端安装轴。 上锁定部分具有围绕安装轴间隔开并位于止动件上方的向外延伸的凸角。 刀片安装轴上的下密封部分位于挡块下方。 当安装轴插入到一次性移液管的轴环中时，套环从圆形变形并与尖端安装轴的上部锁定部分上的凸角接合。 同时，安装轴的下密封部分密封在一次性移液管尖端的筒体上。

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