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    Fault tolerant and combinatorial software environment system, method and medium
    1.
    发明申请
    Fault tolerant and combinatorial software environment system, method and medium 审中-公开
    容错和组合软件环境系统，方法和介质

    公开(公告)号：US20060288345A1

    公开(公告)日：2006-12-21

    申请号：US11296199

    申请日：2005-12-06

    Applicant: Todd Rice ,  Gordon Bennett

    Inventor： Todd Rice ,  Gordon Bennett

    IPC: G06F9/455

    CPC classification number: G06F9/4494

    Abstract: A fault tolerant software environment, in which various program components (e.g., portions of computer programs, applications, etc) are objectized into entities represented by “codons.” This allows for improper syntax to occur, enabling, for example, combinatorial operations such as genetic programming. The present invention also contemplates such features as the ability to probabilistically execute individual codons, to switch between treating information as executable code or as data (or passing over it), provides that the individual codons can be tagged so that additional information can be associated with them, and provides for tagging of the stack.

    Abstract translation: 一种容错软件环境，其中各种程序组件（例如，计算机程序，应用程序的一部分）被对象化为由“密码子”表示的实体。 这允许发生不正确的语法，从而实现例如组合操作，例如遗传编程。 本发明还考虑了这样的特征，即概率地执行个体密码子的能力，在将信息转换为可执行代码或作为数据（或传递给它）之间进行切换，提供可以标记各个密码子，使得附加信息可以与 他们，并提供堆栈的标记。

    System and Method for Analyzing Samples Labeled with 5, 10, 15, 20 Tetrakis (4-Carboxyphenyl) Porphine (TCPP)
    3.
    发明申请
    System and Method for Analyzing Samples Labeled with 5, 10, 15, 20 Tetrakis (4-Carboxyphenyl) Porphine (TCPP) 有权
    用5,10,15,20四（4-羧基苯基）卟吩（TCPP）标记的样品的分析系统和方法

    公开(公告)号：US20110014647A1

    公开(公告)日：2011-01-20

    申请号：US12839283

    申请日：2010-07-19

    Applicant: Constance Dorian ,  John Cousins ,  Gordon Bennett

    Inventor： Constance Dorian ,  John Cousins ,  Gordon Bennett

    IPC: G01N1/30

    CPC classification number: G01N33/5091 ,  G01N21/6428 ,  G01N33/52 ,  G01N33/57423 ,  G01N33/57492 ,  G01N33/582 ,  G01N2021/6439 ,  G01N2458/30 ,  G01N2800/12

    Abstract: One embodiment of the present invention provides for a method of determining if a sputum sample contains dysplastic or carcinomic cells by obtaining a sputum sample containing cells. The sputum sample is labeled with TCPP to stain cells suspected to be dysplastic or carcinomic. The labeled sputum sample is excited with an excitation wavelength of light of about 475 nm+/−30 nm and emission at about 560 nm+/−30 nm is detected from cells identified to be macrophages. An imager focuses on the plasma membrane of one or more cells suspected to be dysplastic or carcinomic and emission at about 655 nm+/−30 nm, if present, is detected for TCPP labeled cells of the sputum sample after focusing on the plasma membrane of the cells of the sputum sample. Photon flux for each pixel of a sensor is measured to obtain a value for the imaged cell. The measured value is scored to determine if a cell is cancerous or dysplastic.

    Abstract translation: 本发明的一个实施方案提供了通过获得含有细胞的痰样品来确定痰样品是否含有发育不良或癌细胞的方法。 痰样品用TCPP标记，以染色疑似发育不良或致癌的细胞。 标记的痰样品用约475nm±30nm的光的激发波长激发，并且从鉴定为巨噬细胞的细胞中检测到在约560nm±30nm的发射。 成像仪聚焦于痰样品的TCPP标记细胞，在聚焦于痰样品的质膜后，检测到怀疑为发育异常或致癌的一个或多个细胞的质膜，并在约655nm±30nm（如果存在） 痰样品的细胞。 测量传感器每个像素的光子通量以获得成像单元的值。 评估测量值以确定细胞是否是癌性或发育异常。

    Orthopedic plate for use in the MTP joint
    5.
    发明申请
    Orthopedic plate for use in the MTP joint 有权
    矫形板用于MTP关节

    公开(公告)号：US20090210010A1

    公开(公告)日：2009-08-20

    申请号：US12378539

    申请日：2009-02-17

    Applicant: Lee A. Strnad ,  Vinay Korlepara ,  Derek S. Lewis ,  Dustin Ducharme ,  Gordon Bennett ,  James Sferra

    Inventor： Lee A. Strnad ,  Vinay Korlepara ,  Derek S. Lewis ,  Dustin Ducharme ,  Gordon Bennett ,  James Sferra

    IPC: A61B17/80

    CPC classification number: A61B17/8061 ,  A61B17/8014 ,  A61B2017/565 ,  Y10S606/906

    Abstract: The present invention is a MTP plate that has a first embodiment with a profile having bilateral mirror symmetry of the about a transverse plane with an angle of about 5° for dorsiflexion and an angle of about 10° for valgus. Both ends of the plate include a central arm having a slot for compression and two offset arms having offset ears with locking screw holes that provide for multiplanar compressive fixation. The bone contacting surface of the plate is radiused to allow the plate to be in snug contact with the bone. In a second embodiment of the plate for revision surgery, the proximal end of the plate includes a metatarsal extension and the plate has a central locking hole for securing bone graft.

    Abstract translation: 本发明是一种MTP板，其具有第一实施例，其轮廓具有围绕横向平面的双侧镜对称性，背屈角为约5°，外翻角为约10°。 板的两端包括具有用于压缩的狭槽的中央臂和具有提供多平面压缩固定的锁定螺钉孔的偏移耳的两个偏移臂。 板的骨接触表面是圆角的，以允许板与骨贴合接触。 在用于修复手术的板的第二实施例中，板的近端包括跖骨延伸部，并且该板具有用于固定骨移植物的中心锁定孔。

    System and method for analyzing samples labeled with 5, 10, 15, 20 tetrakis (4-carboxyphenyl) porphine (TCPP)
    9.
    发明授权
    System and method for analyzing samples labeled with 5, 10, 15, 20 tetrakis (4-carboxyphenyl) porphine (TCPP) 有权
    用5,10,15,20四（4-羧基苯基）卟吩（TCPP）标记的样品进行分析的系统和方法

    公开(公告)号：US08877509B2

    公开(公告)日：2014-11-04

    申请号：US12839283

    申请日：2010-07-19

    Applicant: Constance Dorian ,  John Cousins ,  Gordon Bennett

    Inventor： Constance Dorian ,  John Cousins ,  Gordon Bennett

    IPC: G01N33/48 ,  C12Q1/00 ,  G01N33/574 ,  G01N33/50 ,  G01N33/52 ,  G01N33/58

    CPC classification number: G01N33/5091 ,  G01N21/6428 ,  G01N33/52 ,  G01N33/57423 ,  G01N33/57492 ,  G01N33/582 ,  G01N2021/6439 ,  G01N2458/30 ,  G01N2800/12

    Abstract: One embodiment of the present invention provides for a method of determining if a sputum sample contains dysplastic or carcinomic cells by obtaining a sputum sample containing cells. The sputum sample is labeled with TCPP to stain cells suspected to be dysplastic or carcinomic. The labeled sputum sample is excited with an excitation wavelength of light of about 475 nm+/−30 nm and emission at about 560 nm+/−30 nm is detected from cells identified to be macrophages. An imager focuses on the plasma membrane of one or more cells suspected to be dysplastic or carcinomic and emission at about 655 nm+/−30 nm, if present, is detected for TCPP labeled cells of the sputum sample after focusing on the plasma membrane of the cells of the sputum sample. Photon flux for each pixel of a sensor is measured to obtain a value for the imaged cell. The measured value is scored to determine if a cell is cancerous or dysplastic.

    Abstract translation: 本发明的一个实施方案提供了通过获得含有细胞的痰样品来确定痰样品是否含有发育不良或癌细胞的方法。 痰样品用TCPP标记，以染色疑似发育不良或致癌的细胞。 标记的痰样品用约475nm±30nm的光的激发波长激发，并且从鉴定为巨噬细胞的细胞中检测到在约560nm±30nm的发射。 成像仪聚焦于痰样品的TCPP标记细胞，在聚焦于痰样品的质膜后，检测到怀疑为发育异常或致癌的一个或多个细胞的质膜，并在约655nm±30nm（如果存在） 痰样品的细胞。 测量传感器每个像素的光子通量以获得成像单元的值。 评估测量值以确定细胞是否是癌性或发育异常。

    Narrow band fluorophore exciter
    10.
    发明申请
    Narrow band fluorophore exciter 审中-公开
    窄带荧光激发器

    公开(公告)号：US20130105708A1

    公开(公告)日：2013-05-02

    申请号：US13373032

    申请日：2011-11-02

    Applicant: Gordon Bennett ,  John J. Cousins

    Inventor： Gordon Bennett ,  John J. Cousins

    IPC: G01N21/64 ,  H05B37/02

    CPC classification number: G01N21/6458 ,  G01N2201/062

    Abstract: Disclosed is a solid-state light source based on a light emitting diode (LED) array driven by a constant current power source with an active feedback control. This system can be implemented for broad frequency ranges or for narrow band frequencies depending on the characteristics of the LEDs chosen to populate the array and the geometry of the array. The invention can be used as an excitation light source for fluorescent microscopy and flow cytometry applications as an efficient and stable alternative to existing light sources such as broadband mercury vapor bulbs and plasma-based light sources. Benefits of the current invention include: durability; stability; reduced operating expenses; reduced variance of output; and increased accuracy of frequency and amplitude. This system will provide benefits as the excitation mechanism in fluorescent identification and measurement systems such as microscopy and flow cytometry.

    Abstract translation: 公开了一种基于由具有主动反馈控制的恒流电源驱动的发光二极管（LED）阵列的固态光源。 该系统可以针对宽的频率范围或窄带频率来实现，这取决于被选择填充阵列和阵列的几何形状的LED的特性。 本发明可用作荧光显微镜和流式细胞术应用的激发光源，作为现有光源（例如宽带汞蒸气灯泡和等离子体光源）的有效和稳定的替代方案。 本发明的优点包括：耐久性; 稳定性; 降低经营费用; 产量差异减少; 并提高频率和幅度的精度。 该系统将作为荧光识别和测量系统（如显微镜和流式细胞仪）中的激发机制提供优势。

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