专利检索 ap:"Gad Cojocaru" 第 1 页

1.

发明申请
Methods and systems for annotating biomolecular sequences 审中-公开
标题翻译：注释生物分子序列的方法和系统

公开(公告)号：US20060068405A1

公开(公告)日：2006-03-30

申请号：US11043860

申请日：2005-01-27

申请人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein

发明人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein

IPC分类号： C12Q1/68 , G06F19/00

CPC分类号： C07K14/705 , G16B25/00 , G16B30/00 , G16B50/00

摘要： Polypeptide sequences and polynucleotide sequences are provided. Also provided are annotative information concerning such sequences and uses for these sequences.

摘要翻译： 提供多肽序列和多核苷酸序列。还提供了关于这些序列的这些序列和用途的注释信息。

2.

发明申请
Novel thrombospondin-1 polynucleotides encoding variant thrombospondin-1 polypeptides and methods using same 审中-公开
标题翻译：编码变体血小板反应蛋白-1多肽的新型血小板反应蛋白-1多核苷酸及其使用方法

公开(公告)号：US20070219125A1

公开(公告)日：2007-09-20

申请号：US11709841

申请日：2007-02-23

申请人： Gad Cojocaru , Zurit Levine , Michal Ayalon-Soffer , Amir Toporik , Sarah Pollock , Galit Rotman , Merav Beiman

发明人： Gad Cojocaru , Zurit Levine , Michal Ayalon-Soffer , Amir Toporik , Sarah Pollock , Galit Rotman , Merav Beiman

IPC分类号： A61K38/36 , C07H21/04 , C07K14/745 , C07K16/36 , C12N5/10

CPC分类号： C07K14/78 , A61K38/00

摘要： Novel polypeptides and polynucleotides encoding same are provided. Also provided methods and phamaceutical compositions which can be used to treat various disorders such as cancer and retinopathies, using the polypeptides and polynucleotides of the present invention.

摘要翻译： 提供了新的多肽和编码它们的多核苷酸。还提供了可用于治疗各种疾病如癌症和视网膜病变的方法和药物组合物，使用本发明的多肽和多核苷酸。

3.

发明申请
Novel brain natriuretic peptide variants and methods of use thereof 有权
标题翻译：新型脑利钠肽变体及其使用方法

公开(公告)号：US20050277156A1

公开(公告)日：2005-12-15

申请号：US11043590

申请日：2005-01-27

申请人： Gad Cojocaru , Alexander Diber , Amit Novik , Sarah Pollock , Zurit Levine , Yossi Cohen , Michal Ayalon-Soffer

发明人： Gad Cojocaru , Alexander Diber , Amit Novik , Sarah Pollock , Zurit Levine , Yossi Cohen , Michal Ayalon-Soffer

IPC分类号： A61K38/17 , C07K14/705 , G01N33/53 , G01N33/74

CPC分类号： G01N33/74 , G01N2800/321 , G01N2800/325

摘要： Novel BNP variants. The novel BNP variants according to the present invention may optionally be used for diagnosis of a BNP variant-detectable disease as described herein.

摘要翻译： 新型BNP变体。根据本发明的新型BNP变体可任选地用于本文所述的BNP变体可检测疾病的诊断。

4.

发明申请
Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer 失效
标题翻译：新型核苷酸和氨基酸序列，以及其用于诊断肺癌的测定和方法

公开(公告)号：US20060046257A1

公开(公告)日：2006-03-02

申请号：US11051720

申请日：2005-01-27

申请人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh

发明人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh

IPC分类号： C12Q1/68

CPC分类号： G01N33/57423 , C12Q1/6886 , C12Q2600/112

摘要： Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.

摘要翻译： 肺癌的新型标志物既敏感又准确。与正常肺组织相反，这些标志物特异性地在肺癌中过度表达。这些标记物在患者样本中单独或组合的测量提供了诊断者可以与肺癌可能诊断相关的信息。本发明的标记物单独或组合显示出肺癌和非癌状态之间的高度差异检测。

5.

发明申请
Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of ovarian cancer 审中-公开

公开(公告)号：US20060040278A1

公开(公告)日：2006-02-23

申请号：US11050857

申请日：2005-01-27

申请人： Gad Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar

发明人： Gad Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar

IPC分类号： C12Q1/68 , G01N33/574 , C07H21/04 , C12N15/09 , C07K14/82 , C07K16/30

CPC分类号： G01N33/57449 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158

摘要： Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.

6.

发明申请
Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of cardiac disease 有权
标题翻译：新型核苷酸和氨基酸序列，以及其用于诊断心脏病的测定和方法

公开(公告)号：US20060172311A1

公开(公告)日：2006-08-03

申请号：US11043824

申请日：2005-01-27

申请人： Yossi Cohen , Alexander Diber , Amir Toporik , Sarah Pollock , Zurit Levine , Michal Ayalon-Soffer , Gad Cojocaru , Amit Novik , Guy Kol , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Dvir Dahary , Ronen Shemesh

发明人： Yossi Cohen , Alexander Diber , Amir Toporik , Sarah Pollock , Zurit Levine , Michal Ayalon-Soffer , Gad Cojocaru , Amit Novik , Guy Kol , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Dvir Dahary , Ronen Shemesh

IPC分类号： C12Q1/68 , G01N33/53 , C07H21/04 , C12P21/06 , C07K14/705 , C07K16/28

CPC分类号： G01N33/6893 , C07K14/705 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , G01N2800/324 , G01N2800/325 , G01N2800/327

摘要： Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscle tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markers of the present invention, alone or in combination, show a high degree of differential detection between cardiac disease states and non-cardiac disease states.

摘要翻译： 心脏疾病的新型标志物既敏感又准确。与其他类型的组织相反，这些标记在心脏组织中是有差别地和/或特异性表达的，任选地和优选地包括肌肉组织。这些标记物在患者样本中单独或组合的测量提供了诊断者可以与心脏病的可能诊断相关的信息，包括病理学和/或损伤，包括急性和/或慢性损伤。本发明的标记物单独或组合显示心脏疾病状态与非心脏疾病状态之间的高度差异检测。