Method for searching for homing endonucleases, their genes and their targets
    2.
    发明授权
    Method for searching for homing endonucleases, their genes and their targets 失效
    寻找归巢内切核酸酶,其基因及其靶标的方法

    公开(公告)号:US08566040B2

    公开(公告)日:2013-10-22

    申请号:US12867402

    申请日:2009-02-12

    IPC分类号: G06F19/00 C12Q1/68 C12N9/16

    CPC分类号: G06F19/22 G06F19/28

    摘要: A computer implemented method for generating nucleotide sequences containing candidate homing endonuclease genes (HEGs). A search is performed in a database stored on a storage medium of nucleotide sequences for amino acid sequences having a subsequence having a homology level with the translation of a subsequence of one or more predetermined HEGs. For each amino acid sequence generated by the search, one or more nucleotide sequences are retrieved encoding the amino acid sequence. The results of this search used in a second search of a database stored on a storage medium to generate the HEG containing sequences.

    摘要翻译: 一种用于产生含有候选归巢内切核酸酶基因(HEG)的核苷酸序列的计算机实现方法。 在存储在具有与一个或多个预定HEG的子序列的翻译具有同源性的亚序列的氨基酸序列的核苷酸序列的存储介质上的数据库中进行搜索。 对于通过搜索产生的每个氨基酸序列,检索编码氨基酸序列的一个或多个核苷酸序列。 该搜索的结果用于存储在存储介质上的数据库的第二次搜索以产生包含HEG的序列。

    METHOD FOR SEARCHING FOR HOMING ENDONUCLEASES, THEIR GENES AND THEIR TARGETS
    6.
    发明申请
    METHOD FOR SEARCHING FOR HOMING ENDONUCLEASES, THEIR GENES AND THEIR TARGETS 失效
    搜索内源性杀虫剂的方法,其基因及其目标

    公开(公告)号:US20100317724A1

    公开(公告)日:2010-12-16

    申请号:US12867402

    申请日:2009-02-12

    CPC分类号: G06F19/22 G06F19/28

    摘要: A computer implemented method for generating nucleotide sequences containing candidate homing endonuclease genes (HEGs). A search is performed in a database stored on a storage medium of nucleotide sequences for amino acid sequences having a subsequence having a homology level with the translation of a subsequence of one or more predetermined HEGs. For each amino acid sequence generated by the search, one or more nucleotide sequences are retrieved encoding the amino acid sequence. The results of this search used in a second search of a database stored on a storage medium to generate the HEG containing sequences.

    摘要翻译: 一种用于产生含有候选归巢内切核酸酶基因(HEG)的核苷酸序列的计算机实现方法。 在存储在具有与一个或多个预定HEG的子序列的翻译具有同源性的亚序列的氨基酸序列的核苷酸序列的存储介质上的数据库中进行搜索。 对于通过搜索产生的每个氨基酸序列,检索编码氨基酸序列的一个或多个核苷酸序列。 该搜索的结果用于存储在存储介质上的数据库的第二次搜索以产生包含HEG的序列。