公开(公告)号：US07135540B2

公开(公告)日：2006-11-14

申请号：US10359600

申请日：2003-02-07

申请人： Tsutomu Honma ,  Shinya Kozaki ,  Takeshi Imamura ,  Takashi Kenmoku ,  Tatsuki Fukui ,  Etsuko Sugawa ,  Tetsuya Yano

发明人： Tsutomu Honma ,  Shinya Kozaki ,  Takeshi Imamura ,  Takashi Kenmoku ,  Tatsuki Fukui ,  Etsuko Sugawa ,  Tetsuya Yano

IPC分类号： C08G63/02

CPC分类号： C12P7/625 ,  C08G63/6822 ,  C08G63/6882 ,  C12P11/00

摘要： The invention provides a polyhydroxyalkanoate having a bromo group in a unit and being thermally stable and capable of arbitrarily controlling physical properties, and a producing method thereof. According to the invention, there are provided a polyhydroxyalkanoate copolymer including a 3-hydroxy-ω-bromoalkanoic acid unit represented by a formula—[OCH((CH2)nBr)CH2C(O)]— (n=1 to 8) (1) and a unit represented by a formula —[OCH((CH2)mR)CH2C(O)]— (2) within a same molecule, and a method for producing a polyhydroxyalkanoate copolymer by microorganisms, utilizing a ω-bromoalkanoic acid represented by a formula Br(CH2)pCH2CH2COOH (p=1 to 8) (20) and a compound represented by a formula R(CH2)qCH2CH2COOH (21) as raw materials.

摘要翻译： 本发明提供一种具有溴基团并且是热稳定的并能够任意控制物理性能的聚羟基链烷酸酯及其制备方法。 根据本发明，提供了一种包含由式 - [OCH（（CH 2）n）n Br表示的3-羟基-ω-溴代链烷酸单元的聚羟基链烷酸酯共聚物 ）CH 2 C（O）] - （n = 1-8）（1）和由式 - [OCH（（CH 2）2） （O）] - （2），以及通过微生物制备聚羟基链烷酸酯共聚物的方法，使用由以下化合物表示的ω-溴烷酸： 式（Br 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 COOH（p = 1〜8）（20 ）和由式R（CH 2 CH 2）q CH 2 CH 2 COOH（21）表示的化合物 作为原料。

公开(公告)号：US07045321B2

公开(公告)日：2006-05-16

申请号：US10084172

申请日：2002-02-28

申请人： Takeshi Imamura ,  Etsuko Sugawa ,  Tetsuya Yano ,  Tsuyoshi Nomoto ,  Tomohiro Suzuki ,  Tsutomu Honma ,  Takashi Kenmoku ,  Tatsuki Fukui

发明人： Takeshi Imamura ,  Etsuko Sugawa ,  Tetsuya Yano ,  Tsuyoshi Nomoto ,  Tomohiro Suzuki ,  Tsutomu Honma ,  Takashi Kenmoku ,  Tatsuki Fukui

IPC分类号： C12P11/00 ,  C12P13/00 ,  C08G63/02

CPC分类号： G03G9/08755 ,  C08G63/6882 ,  C12P7/625 ,  C12P11/00 ,  G03G9/08791 ,  G03G9/09733 ,  G03G9/09775

摘要： A polyhydroxyalkanoate characterized by having in the molecule a unit represented by Chemical Formula (1): wherein n may assume any one integral value within the range of from 1 to 8. Also disclosed are a process for producing the polyhydroxyalkanoate by the use of a microorganism having the ability to produce the polyhydroxyalkanoate and accumulate it in the bacterial body; a charge control agent, a toner binder and a toner which contain this polyhydroxyalkanoate; and an image-forming method and an image-forming apparatus which make use of the toner.

摘要翻译： 公开了在分子中具有由化学式（1）表示的单元的聚羟基链烷酸酯。 其中R选自氢原子，卤原子，CN，NO 2，COOR'，SO 2 R“，CH 3，C 2 H 5，C 3 H 7，C（CH 3）2 H和C（CH 3）3; 其中R'是H，Na，K，CH3或C2H5，R“是OH，ONa，OK，卤素原子，OCH3或OC2H5; x是任意选自1至8的整数; 条件是排除了具有氢原子作为R的聚羟基链烷酸酯，并且所有单元中的x均为2或4.还公开了通过使用具有生产聚羟基链烷酸酯的能力的微生物来生产聚羟基链烷酸酯并累积 它在细菌体内

公开(公告)号：US06911521B2

公开(公告)日：2005-06-28

申请号：US10157142

申请日：2002-05-30

申请人： Takashi Kenmoku ,  Etsuko Sugawa ,  Tetsuya Yano ,  Tsuyoshi Nomoto ,  Takeshi Imamura ,  Tomohiro Suzuki ,  Tsutomu Honma

发明人： Takashi Kenmoku ,  Etsuko Sugawa ,  Tetsuya Yano ,  Tsuyoshi Nomoto ,  Takeshi Imamura ,  Tomohiro Suzuki ,  Tsutomu Honma

IPC分类号： C08G63/06 ,  C08G63/02 ,  C08G63/688 ,  C08G63/78 ,  C12P7/62 ,  C12P11/00

CPC分类号： C12P11/00 ,  C08G63/6882 ,  C12P7/625

摘要： A polyhydroxyalkanoate that comprises a unit represented by the following chemical formula (1): wherein R1 is a substituent of an aromatic ring selected from the group consisting of H, CH3, C2H5, CH3CH2CH2, (CH3)2CH, (CH3)3C, a halogen atom, CN, NO2, COOR′, and SO2R″, wherein R′ is selected from the group consisting of H, Na, K, CH3, and C2H5, and R″ is selected from the group consisting of OH, a halogen atom, ONa, OK, OCH3, and OC2H5; and x represents an integer of 1 to 8 being the same or different each other in the polyhydroxyalkanoate. A method for producing the polyhydroxyalkanoate is also provided.

摘要翻译： 一种聚羟基链烷酸酯，其包含由以下化学式（1）表示的单元：其中R1是选自H，CH 3，C 2， CH 3，CH 3，CH 2，CH 2，CH 3，CH 3，CH 3，CH 3， ）CH 2（CH 3）3 C，卤素原子，CN，NO 2，COOR' ，和SO 2 R“，其中R'选自H，Na，K，CH 3，和C 2 H 5，并且R“选自OH，卤素原子，ONa，OK，OCH 3和OC 2， 5 H 5; x表示在聚羟基链烷酸酯中相同或不同的1〜8的整数。 还提供了生产聚羟基链烷酸酯的方法。

公开(公告)号：US06911520B2

公开(公告)日：2005-06-28

申请号：US10373851

申请日：2003-02-27

申请人： Tatsuki Fukui ,  Etsuko Sugawa ,  Tetsuya Yano ,  Chieko Mihara ,  Takeshi Imamura ,  Takashi Kenmoku

发明人： Tatsuki Fukui ,  Etsuko Sugawa ,  Tetsuya Yano ,  Chieko Mihara ,  Takeshi Imamura ,  Takashi Kenmoku

IPC分类号： C08G63/06 ,  C08G63/688 ,  C08G63/91 ,  C08L101/16 ,  G03G9/087 ,  G03G9/097 ,  C08G63/02

CPC分类号： C08G63/912 ,  C08G63/06 ,  C08G63/6882 ,  G03G9/08791 ,  G03G9/097 ,  G03G9/09733

摘要： Provided is a polyhydroxyalkanoate containing in a molecule thereof one or more units each selected from the following formulae (1) (2), (3) and (4): wherein R1 and R6 are each OH, halogen, ONa, OK, OCH3 or OC2H5; A1 and J6 are each a substituted or unsubstituted aliphatic hydrocarbon; m and n are each 0 to 7; r is 1 to 500; and R1′ to R5′ are each hydrogen or halogen.

摘要翻译： 提供一种分子中含有一个或多个选自下式（1）（3）和（4）中的单元的聚羟基链烷酸酯：其中R 1和R 6 每个OH，卤素，ONa，OK，OCH 3或OC 2 H 5; A 1和J 6各自为取代或未取代的脂族烃; m和n各自为0至7; r为1〜500; R 1至R 5'各自为氢或卤素。

公开(公告)号：US06908721B2

公开(公告)日：2005-06-21

申请号：US10367951

申请日：2003-02-19

申请人： Takashi Kenmoku ,  Etsuko Sugawa ,  Tetsuya Yano ,  Chieko Mihara ,  Takeshi Imamura ,  Tatsuki Fukui

发明人： Takashi Kenmoku ,  Etsuko Sugawa ,  Tetsuya Yano ,  Chieko Mihara ,  Takeshi Imamura ,  Tatsuki Fukui

IPC分类号： G03G9/097 ,  C08G63/688 ,  C08G63/91 ,  C08L101/16 ,  C12P7/62 ,  C12P11/00 ,  G03G9/087 ,  C08G63/02

CPC分类号： G03G9/08755 ,  C08G63/6882 ,  C08G63/912 ,  C12P7/625 ,  C12P11/00 ,  G03G9/08791

摘要： A polyhydroxyalkanoate comprises a unit of formula (1): —(O—CH((CH2)mSASO2R)CH2C(═O))— wherein R is selected from the group consisting of OH, a halogen atom, ONa, OK, OCH3 and OC2H5; A represents a substituted or unsubstituted aliphatic hydrocarbon structure; m is an integer number selected from 1 to 8; and in the case where a plurality of units exist in the same molecule, R, A and m in one unit can be different from them in another unit respectively. A method of producing the polyhydroxyalkanoate comprises the step of reacting a polyhydroxyalkanoate comprising a unit of formula (18): —(O—CH((CH2)mBr)CH2C(═O))—, wherein m is an integer number selected from 1 to 8, and in the case where a plurality of units exist in the same molecule, m in one unit can be different from that in another unit, with at least one type of compounds of formula (19): HS-A1-SO2R15 wherein R15 is selected from the group consisting of OH, a halogen atom, ONa, OK, OCH3 and OC2H5 and A1 is a substituted or unsubstituted aliphatic hydrocarbon structure, and in the case where a plurality of types of compounds exist in the same molecule, R15 and A1 in one unit can be different from them in another unit respectively.

摘要翻译： 聚羟基链烷酸酯包含式（1）的单元： - （O-CH（（CH 2）2）NH 2 R 2 CH 2 （O）） - 其中R选自OH，卤素原子，ONa，OK，OCH 3和OC 2 可以分别与另一个单元中的不同。

公开(公告)号：US06908720B2

公开(公告)日：2005-06-21

申请号：US10133576

申请日：2002-04-29

申请人： Takashi Kenmoku ,  Toyoko Kobayashi ,  Etsuko Sugawa ,  Tetsuya Yano ,  Shin Kobayashi ,  Takeshi Imamura ,  Tsutomu Honma

发明人： Takashi Kenmoku ,  Toyoko Kobayashi ,  Etsuko Sugawa ,  Tetsuya Yano ,  Shin Kobayashi ,  Takeshi Imamura ,  Tsutomu Honma

IPC分类号： C08G63/688 ,  C12P7/62 ,  C12P11/00 ,  G03G9/087 ,  G03G9/097 ,  C08G13/06 ,  C08F20/00

CPC分类号： G03G9/08771 ,  C08G63/6882 ,  C12P7/625 ,  C12P11/00 ,  G03G9/08728 ,  G03G9/0874 ,  G03G9/08768 ,  G03G9/08773 ,  G03G9/08791 ,  G03G9/08795 ,  G03G9/08797 ,  G03G9/09733 ,  G03G9/09775

摘要： The present invention provides a novel PHA comprising a unit containing thioether with high reactivity, and its production method. The present invention also provides polyhydroxyalkanoate (PHA) comprising units having defined chemical formulas (1) and (2), and at least one of four units having defined chemical formulas (3), (4), (5) and (6); its production method; a charge control agent containing the PHA; a toner binder containing the charge control agent; an electrostatic latent image developing toner; and an image forming method and an image forming apparatus using the electrostatic latent image developing toner.

摘要翻译： 本发明提供了包含含有高反应性的硫醚的单元的新型PHA及其制造方法。 本发明还提供了包含具有确定的化学式（1）和（2）的单元和具有确定的化学式（3），（4），（5）和（6）的四个单元中的至少一个的聚羟基链烷酸酯（PHA） 其生产方式; 含有PHA的电荷控制剂; 含有电荷控制剂的调色剂粘合剂; 静电潜像显影调色剂; 以及使用静电潜像显影用调色剂的图像形成方法和图像形成装置。

公开(公告)号：US06869782B2

公开(公告)日：2005-03-22

申请号：US10187808

申请日：2002-07-03

申请人： Takashi Kenmoku ,  Etsuko Sugawa ,  Tetsuya Yano ,  Takeshi Imamura

发明人： Takashi Kenmoku ,  Etsuko Sugawa ,  Tetsuya Yano ,  Takeshi Imamura

IPC分类号： C08G63/49 ,  C08G63/688 ,  C12P7/62 ,  C12P11/00 ,  C08G63/02 ,  C08G79/00

CPC分类号： C12P11/00 ,  C08G63/6882 ,  C12P7/625

摘要： A polyhydroxyalkanoate that comprises a unit represented by the following chemical formula (1): wherein x is an integer of 1 to 8 being the same or different in the polyhydroxyalkanoate. The microbial production process is also disclosed.

摘要翻译： 包含由以下化学式（1）表示的单元的聚羟基链烷酸酯：其中x是1至8的整数，在聚羟基链烷酸酯中相同或不同。 还公开了微生物生产过程。

公开(公告)号：US06855472B2

公开(公告)日：2005-02-15

申请号：US10133379

申请日：2002-04-29

申请人： Takeshi Imamura ,  Etsuko Sugawa ,  Tetsuya Yano ,  Takashi Kenmoku

发明人： Takeshi Imamura ,  Etsuko Sugawa ,  Tetsuya Yano ,  Takashi Kenmoku

IPC分类号： C08G63/49 ,  C08G63/688 ,  C12P7/62 ,  C12P11/00 ,  G03G9/087 ,  G03G9/08 ,  C08C75/00

CPC分类号： C12P11/00 ,  C08G63/6882 ,  C12P7/625 ,  G03G9/08755

摘要： The invention is to provide polyhydroxyalkanoate of a novel structure enabling application to wider fields, and a producing method therefor. The invention also provides a biodegradable charge control agent having excellent charging characteristics, excellent dispersibility in the toner resin and improved spent property. The polyhydroxyalkanoate of the present invention is featured by including, in the polymer molecule, a units represented by the general formulas (1) and (2) and at least one of the units represented by the general formulas (3) to (6).

摘要翻译： 本发明提供具有能够应用于更广领域的新型结构的聚羟基链烷酸酯及其制造方法。 本发明还提供了具有优异的充电特性，在调色剂树脂中优异的分散性和改善的废弃性能的可生物降解的电荷控制剂。 本发明的聚羟基链烷酸酯的特征在于，在聚合物分子中包含由通式（1）和（2）表示的单元和由通式（3）〜（6）表示的单元中的至少一个。

公开(公告)号：US06808907B2

公开(公告)日：2004-10-26

申请号：US10105332

申请日：2002-03-26

申请人： Tsutomu Honma ,  Etsuko Sugawa ,  Tetsuya Yano ,  Tsuyoshi Nomoto ,  Takeshi Imamura ,  Tomohiro Suzuki ,  Takashi Kenmoku

发明人： Tsutomu Honma ,  Etsuko Sugawa ,  Tetsuya Yano ,  Tsuyoshi Nomoto ,  Takeshi Imamura ,  Tomohiro Suzuki ,  Takashi Kenmoku

IPC分类号： C12P762

CPC分类号： C12P7/625 ,  C12M47/06

摘要： The present invention provides a method for producing highly purified polyhydroxyalkanoate (PHA) with high yield, by removing cell components other than PHA from cells containing PHA. Moreover, the present invention provides a method for simply removing or reducing chlorine remained in the collected PHA particles, when a treatment with an oxidizing agent containing hypochlorite is performed in the production of PHA as described above. One of the above-described methods comprises a step of treating cells containing polyhydroxyalkanoate with an oxidizing agent containing at least hypochlorite, a step of separating the treated cells into a water-soluble fraction and a water-insoluble fraction, and a step of reducing chlorine remained in the water-insoluble fraction. The step of reducing chlorine may be a step of washing the water-insoluble fraction with a hot water, thiosulfate solution or polar solvent solution containing at least an organic polar solvent in which polyhydroxyalkanoate is insoluble.

摘要翻译： 本发明提供了通过从含有PHA的细胞中除去PHA以外的细胞成分而以高产率生产高纯度聚羟基链烷酸酯（PHA）的方法。 此外，本发明提供了如上所述在生产PHA中进行含有次氯酸盐的氧化剂的处理时，简单地除去或还原所收集的PHA颗粒中残留的氯的方法。 上述方法之一包括用至少含有次氯酸盐的氧化剂处理含有聚羟基链烷酸酯的细胞的步骤，将经处理的细胞分离成水溶性级分和水不溶性级分的步骤以及还原氯 保留在水不溶性部分中。 还原氯的步骤可以是用至少含有聚羟基链烷酸酯不溶的有机极性溶剂的热水，硫代硫酸盐溶液或极性溶剂溶液洗涤水不溶性部分的步骤。

公开(公告)号：US06645743B1

公开(公告)日：2003-11-11

申请号：US10372285

申请日：2003-02-25

申请人： Tsutomu Honma ,  Etsuko Sugawa ,  Tetsuya Yano ,  Takeshi Imamura ,  Takashi Kenmoku ,  Tatsuki Fukui

发明人： Tsutomu Honma ,  Etsuko Sugawa ,  Tetsuya Yano ,  Takeshi Imamura ,  Takashi Kenmoku ,  Tatsuki Fukui

IPC分类号： C12P742

CPC分类号： C08G63/06 ,  C08G63/6882 ,  C12P7/625 ,  C12P11/00 ,  Y10S435/874 ,  Y10S435/877

摘要： A polyhydroxyalkanoate (PHA) having a desired configuration is produced using a raw material containing &ohgr;-(4-vinylphenyl)-alkanoic acid and (&ohgr;-substituted alkanoic acid in which a group having a ring structure selected from phenyl, thienyl, and cyclohexyl structures substitutes therefor on the end thereof by producing a PHA copolymer containing the corresponding 3-hydroxy-&ohgr;-(4-vinylphenyl)-alkanoate unit and the corresponding 3-hydroxy-&ohgr;-substituted alkanoate unit by making use of a microorganism capable of producing the PHA or by oxidizing a predetermined portion of the corresponding PHA.

摘要翻译： 使用含有ω-（4-乙烯基苯基） - 链烷酸的原料和（其中具有选自苯基，噻吩基和环己基结构的环结构的基团的（ω-取代的链烷酸）制备具有所需构型的聚羟基链烷酸酯（PHA） 通过制备含有相应的3-羟基-ω-（4-乙烯基苯基） - 烷酸酯单元和相应的3-羟基-ω-取代的链烷酸酯单元的PHA共聚物，通过使用能够产生 或通过氧化相应PHA的预定部分。