公开(公告)号：US08450101B2

公开(公告)日：2013-05-28

申请号：US12799410

申请日：2010-04-22

申请人： Sayaka Gomi ,  Shuichi Akashi ,  Daisuke Numai ,  Ryoko Imagawa ,  Masaaki Chino ,  Eiji Kawata ,  Masahiko Amano

发明人： Sayaka Gomi ,  Shuichi Akashi ,  Daisuke Numai ,  Ryoko Imagawa ,  Masaaki Chino ,  Eiji Kawata ,  Masahiko Amano

IPC分类号： C12M1/00 ,  C12M1/36 ,  G01N21/00

CPC分类号： B01L3/502723 ,  B01L3/5025 ,  B01L3/50851 ,  B01L3/527 ,  B01L7/52 ,  B01L2200/0642 ,  B01L2200/0684 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0655 ,  B01L2400/0677 ,  B01L2400/084 ,  G01N2035/00158 ,  G01N2035/00366

摘要： The reaction chip of the present invention has a plurality of recesses 6 constituting a part of a reaction container and a groove constituting a part of a channel formed on at least one of one face of a first base material (resin base material 2) and one face of a second base material (metallic base material) and a notch 15 showing a gradual increase in width and a gradual increase in depth from one face 2d of the base material toward an inner wall surface 6d of the recess is formed on an edge of at least one recess in an extending direction of the groove. One face of the first base material and one face of the second base material are stuck together opposite to each other to form the plurality of reaction containers and the channel.

摘要翻译： 本发明的反应芯片具有构成反应容器的一部分的多个凹部6和构成在第一基材（树脂基材2）的一个面的至少一个上形成的通道的一部分的槽和一个 第二基材（金属基材）的表面和表示从基材的一个面2d朝向凹部的内壁面6d的宽度逐渐增加和深度逐渐增加的切口15形成在 在槽的延伸方向上的至少一个凹部。 第一基材的一个面和第二基材的一个面彼此相对地粘合在一起，以形成多个反应容器和通道。

公开(公告)号：US20100227383A1

公开(公告)日：2010-09-09

申请号：US12452345

申请日：2008-06-27

申请人： Masahiko Amano ,  Masaaki Chino ,  Hiroyuki Kuroki ,  Makiko Dejima ,  Tomoyuki Ozawa ,  Eiji Kawata ,  Ryoko Imagawa ,  Shuichi Akashi ,  Yusuke Nakamura ,  Eiji Yamamoto ,  Katsuhiro Tomaru ,  Hajime Mogi

发明人： Masahiko Amano ,  Masaaki Chino ,  Hiroyuki Kuroki ,  Makiko Dejima ,  Tomoyuki Ozawa ,  Eiji Kawata ,  Ryoko Imagawa ,  Shuichi Akashi ,  Yusuke Nakamura ,  Eiji Yamamoto ,  Katsuhiro Tomaru ,  Hajime Mogi

IPC分类号： C12M1/34

CPC分类号： B01L7/52 ,  B01L3/505 ,  B01L3/50851 ,  B01L7/5255 ,  B01L2200/0642 ,  B01L2300/0829 ,  B01L2300/123 ,  G01N35/026 ,  G01N2035/00346 ,  H01L2924/0002 ,  H01L2924/00

摘要： A genetic detection and determination apparatus which detects or determines genetic information, provided with a reaction container having a reaction vessel, including: a container set portion on which the reaction container is set; a moving mechanism which moves the container set portion along a track; a reaction vessel dividing portion which divides the reaction vessel into a plurality of reaction chambers by deforming the reaction vessel; a heating and cooling portion which heats and cools the reaction container; and a measuring portion which is movable above the container set portion in parallel to an upper surface of the reaction container provided on the container set portion and which measures a reaction within each of the reaction chambers.

摘要翻译： 一种检测或确定遗传信息的遗传检测和确定装置，其具有包括反应容器的反应容器，包括：设置反应容器的容器组合部分; 移动机构，其沿着轨道移动容器设定部; 反应容器分隔部，其通过使反应容器变形而将反应容器分割成多个反应室; 加热和冷却反应容器的加热和冷却部分; 以及测量部分，其在容器设置部分上方平行于设置在容器组部分上的反应容器的上表面上移动并且测量每个反应室内的反应。

公开(公告)号：US5441097A

公开(公告)日：1995-08-15

申请号：US242885

申请日：1994-05-16

申请人： Tetsuo Kanda ,  Eiji Kawata ,  Noboru Ikeda ,  Manami Miyazaki

发明人： Tetsuo Kanda ,  Eiji Kawata ,  Noboru Ikeda ,  Manami Miyazaki

IPC分类号： F24F5/00 ,  F28D20/02 ,  F28D19/00

CPC分类号： F28D20/0034 ,  F28D20/02 ,  F28D2020/0021 ,  Y02E60/142 ,  Y02E60/145

摘要： A heat storage tank in which heat storage and heat discharge operations are carried out through heat-exchange between heat storage agent and heat transfer medium to store electric power as latent heat, including plural heat storage members which are arranged in a fill-up state in the heat storage tank, each heat storage member holding therein the heat storage agent which alternately repeats latent heat storing and discharging operations through solid-liquid phase variation thereof, and comprising an elongated hollow container formed of material which can keep itself in a hollow shape. The heat storage members are arranged with their open end portions faced up and so as to be spaced from one another at such an interval that the heat transfer medium can flow through gaps between neighboring heat storage members, then the heat storage agent is supplied through the open ends into the heat storage members, and then the heat transfer medium is supplied into the heat storage tank. Each heat storage member is provided with a spacer at least one position on its peripheral surface, and the heat storage members are fixedly assembled and bundled through the spacers thereof. These bundles of the heat storage members are arranged in a fill-up state in the heat storage tank.

摘要翻译： 一种蓄热箱，其特征在于，通过蓄热剂和传热介质之间的热交换进行蓄热放热，蓄电用作潜热，包括以填充状态配置的多个蓄热构件 储热箱，每个蓄热构件保持蓄热剂，其通过其固液相变而交替重复潜热储存和排放操作，并且包括由能够保持其自身处于中空形状的材料形成的细长中空容器。 蓄热构件的开放端部被面对并且以与传热介质可以流过相邻的蓄热构件之间的间隙的间隔彼此间隔开地布置，然后将蓄热剂通过 开放端部进入蓄热构件，然后将传热介质供应到储热箱中。 每个蓄热构件在其外周表面上设置有至少一个位置的间隔件，并且蓄热构件被固定地组装并通过其间隔件捆扎。 这些蓄热构件的束在蓄热槽中以填充状态排列。

公开(公告)号：US09267890B2

公开(公告)日：2016-02-23

申请号：US13498818

申请日：2010-09-30

申请人： Eiji Kawata ,  Shuichi Akashi ,  Hiroyuki Kuroki

发明人： Eiji Kawata ,  Shuichi Akashi ,  Hiroyuki Kuroki

IPC分类号： B01L1/00 ,  B01L3/00 ,  G01N21/64 ,  G01N21/07 ,  G01N35/00 ,  G01N21/03

CPC分类号： G01N21/6452 ,  B01L3/50825 ,  B01L3/50851 ,  B01L2200/0615 ,  B01L2200/0673 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2300/044 ,  B01L2300/0803 ,  B01L2300/1805 ,  G01N21/07 ,  G01N35/00069 ,  G01N35/0099 ,  G01N35/04 ,  G01N2021/0325 ,  G01N2035/00356 ,  G01N2035/046 ,  G01N2035/103

摘要： A nucleic acid analyzer includes a nucleic acid purification kit yielding a nucleic acid solution by isolating and purifying nucleic acid from a specimen; a nucleic acid analysis chip having a rotation axis positioned at a center thereof, with reaction containers at an outer portion than the rotation axis, and feeding the acid to the containers through centrifugal force; a specimen-introducing part on which the kit is placed; an analysis chip holder at the specimen-introducing part and supporting the chip; a purification treatment unit injecting the nucleic acid solution containing the nucleic acid into the chip; a centrifugal liquid feed unit feeding the nucleic acid solution to the containers by rotating the chip about the rotation axis; an analysis unit analyzing reaction products in the containers; and a transport part transporting the specimen-introducing part to the purification treatment unit, the centrifugal liquid feed unit, and the analysis unit.

摘要翻译： 核酸分析仪包括通过从样品中分离和纯化核酸而产生核酸溶液的核酸纯化试剂盒; 具有位于其中心的旋转轴的核酸分析芯片，反应容器位于比旋转轴线更外侧的部分，并且通过离心力将酸供给到容器中; 其上放置有试剂盒的样品引入部分; 在样品引入部分处分析芯片保持器并支撑芯片; 将含有核酸的核酸溶液注入芯片的净化处理单元; 离心液体供给单元，通过围绕旋转轴旋转芯片将核酸溶液供给到容器; 分析容器中的反应产物的分析单元; 以及将试样导入部输送到净化处理单元，离心液供给单元和分析单元的输送部。

公开(公告)号：US08828712B2

公开(公告)日：2014-09-09

申请号：US12452345

申请日：2008-06-27

申请人： Masahiko Amano ,  Masaaki Chino ,  Hiroyuki Kuroki ,  Makiko Dejima ,  Tomoyuki Ozawa ,  Eiji Kawata ,  Ryoko Imagawa ,  Shuichi Akashi ,  Yusuke Nakamura ,  Eiji Yamamoto ,  Katsuhiro Tomaru ,  Hajime Mogi

发明人： Masahiko Amano ,  Masaaki Chino ,  Hiroyuki Kuroki ,  Makiko Dejima ,  Tomoyuki Ozawa ,  Eiji Kawata ,  Ryoko Imagawa ,  Shuichi Akashi ,  Yusuke Nakamura ,  Eiji Yamamoto ,  Katsuhiro Tomaru ,  Hajime Mogi

IPC分类号： C12M1/00 ,  C12M1/34 ,  C12M1/36 ,  C12M1/38 ,  C12M3/00 ,  B01L7/00 ,  B01L3/00 ,  G01N35/02 ,  G01N35/00

CPC分类号： B01L7/52 ,  B01L3/505 ,  B01L3/50851 ,  B01L7/5255 ,  B01L2200/0642 ,  B01L2300/0829 ,  B01L2300/123 ,  G01N35/026 ,  G01N2035/00346 ,  H01L2924/0002 ,  H01L2924/00

摘要： A genetic detection and determination apparatus which detects or determines genetic information, provided with a reaction container having a reaction vessel, including: a container set portion on which the reaction container is set; a moving mechanism which moves the container set portion along a track; a reaction vessel dividing portion which divides the reaction vessel into a plurality of reaction chambers by deforming the reaction vessel; a heating and cooling portion which heats and cools the reaction container; and a measuring portion which is movable above the container set portion in parallel to an upper surface of the reaction container provided on the container set portion and which measures a reaction within each of the reaction chambers.

摘要翻译： 一种检测或确定遗传信息的遗传检测和确定装置，其具有包括反应容器的反应容器，包括：设置反应容器的容器组合部分; 移动机构，其沿着轨道移动容器设定部; 反应容器分隔部，其通过使反应容器变形而将反应容器分割成多个反应室; 加热和冷却反应容器的加热和冷却部分; 以及测量部分，其在容器设置部分上方平行于设置在容器组部分上的反应容器的上表面上移动并且测量每个反应室内的反应。

公开(公告)号：US20120322141A1

公开(公告)日：2012-12-20

申请号：US13573143

申请日：2012-08-23

申请人： Sayaka GOMI ,  Shuichi AKASHI ,  Daisuke NUMAI ,  Ryoko IMAGAWA ,  Masaaki CHINO ,  Eiji KAWATA ,  Masahiko AMANO

发明人： Sayaka GOMI ,  Shuichi AKASHI ,  Daisuke NUMAI ,  Ryoko IMAGAWA ,  Masaaki CHINO ,  Eiji KAWATA ,  Masahiko AMANO

IPC分类号： C12M1/00

CPC分类号： B01L3/502723 ,  B01L3/5025 ,  B01L3/50851 ,  B01L3/527 ,  B01L7/52 ,  B01L2200/0642 ,  B01L2200/0684 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0655 ,  B01L2400/0677 ,  B01L2400/084 ,  G01N2035/00158 ,  G01N2035/00366

摘要： The reaction chip of the present invention has a plurality of recesses 6 constituting a part of a reaction container and a groove constituting a part of a channel formed on at least one of one face of a first base material (resin base material 2) and one face of a second base material (metallic base material) and a notch 15 showing a gradual increase in width and a gradual increase in depth from one face 2d of the base material toward an inner wall surface 6d of the recess is formed on an edge of at least one recess in an extending direction of the groove. One face of the first base material and one face of the second base material are stuck together opposite to each other to form the plurality of reaction containers and the channel.

摘要翻译： 本发明的反应芯片具有构成反应容器的一部分的多个凹部6和构成在第一基材（树脂基材2）的一个面的至少一个上形成的通道的一部分的槽和一个 第二基材（金属基材）的表面和表示从基材的一个面2d朝向凹部的内壁面6d的宽度逐渐增加和深度逐渐增加的切口15形成在 在槽的延伸方向上的至少一个凹部。 第一基材的一个面和第二基材的一个面彼此相对地粘合在一起，以形成多个反应容器和通道。

公开(公告)号：US20100216193A1

公开(公告)日：2010-08-26

申请号：US12799410

申请日：2010-04-22

申请人： Sayaka Gomi ,  Shuichi Akashi ,  Daisuke Numai ,  Ryoko Imagawa ,  Masaaki Chino ,  Eiji Kawata ,  Masahiko Amano

发明人： Sayaka Gomi ,  Shuichi Akashi ,  Daisuke Numai ,  Ryoko Imagawa ,  Masaaki Chino ,  Eiji Kawata ,  Masahiko Amano

IPC分类号： G01N37/00 ,  C12M1/00 ,  C12M1/38

CPC分类号： B01L3/502723 ,  B01L3/5025 ,  B01L3/50851 ,  B01L3/527 ,  B01L7/52 ,  B01L2200/0642 ,  B01L2200/0684 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0655 ,  B01L2400/0677 ,  B01L2400/084 ,  G01N2035/00158 ,  G01N2035/00366

摘要： The reaction chip of the present invention has a plurality of recesses 6 constituting a part of a reaction container and a groove constituting a part of a channel formed on at least one of one face of a first base material (resin base material 2) and one face of a second base material (metallic base material) and a notch 15 showing a gradual increase in width and a gradual increase in depth from one face 2d of the base material toward an inner wall surface 6d of the recess is formed on an edge of at least one recess in an extending direction of the groove. One face of the first base material and one face of the second base material are stuck together opposite to each other to form the plurality of reaction containers and the channel.

摘要翻译： 本发明的反应芯片具有构成反应容器的一部分的多个凹部6和构成在第一基材（树脂基材2）的一个面的至少一个上形成的通道的一部分的槽和一个 第二基材（金属基材）的表面和表示从基材的一个面2d朝向凹部的内壁面6d的宽度逐渐增加和深度逐渐增加的切口15形成在 在槽的延伸方向上的至少一个凹部。 第一基材的一个面和第二基材的一个面彼此相对地粘合在一起，以形成多个反应容器和通道。

公开(公告)号：US5036904A

公开(公告)日：1991-08-06

申请号：US566759

申请日：1990-08-14

申请人： Tetsuo Kanda ,  Yuichiro Hara ,  Kazuma Kawano ,  Eiji Kawata ,  Kenichi Okuda

发明人： Tetsuo Kanda ,  Yuichiro Hara ,  Kazuma Kawano ,  Eiji Kawata ,  Kenichi Okuda

IPC分类号： F28D20/02

CPC分类号： F28D20/021 ,  Y02E60/145

摘要： A latent heat storage tank is filled with antifreeze solution such as ethylene glycol, propylene glycol, calcium chloride and a plurality of bundles of cylindrical latent heat containers in the form of tubes or pipes which float perpendicularly to the antifreeze surface. The antifreeze solution is circulated by a refrigerator provided outside the latent heat storage tank. Each cylindrical latent heat container contains water or other liquid which is cooled to become ice by said antifreeze solution which has been cooled by said refrigerator driven by inexpensive night time electric power.

摘要翻译： 潜热储罐中装有乙二醇，丙二醇，氯化钙等防冻溶液，以及垂直于防冻表面漂浮的管或管的形式的多个圆柱形潜热容器束。 防冻溶液通过设置在潜热蓄热箱外部的冰箱循环。 每个圆柱形潜热容器都含有水或其它冷却成为冰的液体，所述冷冻溶液已经被廉价的夜间电力驱动的所述冰箱冷却。

公开(公告)号：US20120184025A1

公开(公告)日：2012-07-19

申请号：US13498818

申请日：2010-09-30

申请人： Eiji Kawata ,  Shuichi Akashi ,  Hiroyuki Kuroki

发明人： Eiji Kawata ,  Shuichi Akashi ,  Hiroyuki Kuroki

IPC分类号： C12M1/34

CPC分类号： G01N21/6452 ,  B01L3/50825 ,  B01L3/50851 ,  B01L2200/0615 ,  B01L2200/0673 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2300/044 ,  B01L2300/0803 ,  B01L2300/1805 ,  G01N21/07 ,  G01N35/00069 ,  G01N35/0099 ,  G01N35/04 ,  G01N2021/0325 ,  G01N2035/00356 ,  G01N2035/046 ,  G01N2035/103

摘要： A nucleic acid analyzer includes a nucleic acid purification kit yielding a nucleic acid solution by isolating and purifying nucleic acid from a specimen; a nucleic acid analysis chip having a rotation axis positioned at a center thereof, with reaction containers at an outer portion than the rotation axis, and feeding the acid to the containers through centrifugal force; a specimen-introducing part on which the kit is placed; an analysis chip holder at the specimen-introducing part and supporting the chip; a purification treatment unit injecting the nucleic acid solution containing the nucleic acid into the chip; a centrifugal liquid feed unit feeding the nucleic acid solution to the containers by rotating the chip about the rotation axis; an analysis unit analyzing reaction products in the containers; and a transport part transporting the specimen-introducing part to the purification treatment unit, the centrifugal liquid feed unit, and the analysis unit.

摘要翻译： 核酸分析仪包括通过从样品中分离和纯化核酸而产生核酸溶液的核酸纯化试剂盒; 具有位于其中心的旋转轴的核酸分析芯片，反应容器位于比旋转轴线更外侧的部分，并且通过离心力将酸供给到容器中; 其上放置有试剂盒的样品引入部分; 在样品引入部分处分析芯片保持器并支撑芯片; 将含有核酸的核酸溶液注入芯片的净化处理单元; 离心液体供给单元，通过围绕旋转轴旋转芯片将核酸溶液供给到容器; 分析容器中的反应产物的分析单元; 以及将试样导入部输送到净化处理单元，离心液供给单元和分析单元的输送部。

公开(公告)号：US20120322110A1

公开(公告)日：2012-12-20

申请号：US13573138

申请日：2012-08-23

申请人： Sayaka GOMI ,  Shuichi AKASHI ,  Daisuke NUMAI ,  Ryoko IMAGAWA ,  Masaaki CHINO ,  Eiji KAWATA ,  Masahiko AMANO

发明人： Sayaka GOMI ,  Shuichi AKASHI ,  Daisuke NUMAI ,  Ryoko IMAGAWA ,  Masaaki CHINO ,  Eiji KAWATA ,  Masahiko AMANO

IPC分类号： C12P19/34

CPC分类号： B01L3/502723 ,  B01L3/5025 ,  B01L3/50851 ,  B01L3/527 ,  B01L7/52 ,  B01L2200/0642 ,  B01L2200/0684 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0655 ,  B01L2400/0677 ,  B01L2400/084 ,  G01N2035/00158 ,  G01N2035/00366

摘要： The reaction chip of the present invention has a plurality of recesses 6 constituting a part of a reaction container and a groove constituting a part of a channel formed on at least one of one face of a first base material (resin base material 2) and one face of a second base material (metallic base material) and a notch 15 showing a gradual increase in width and a gradual increase in depth from one face 2d of the base material toward an inner wall surface 6d of the recess is formed on an edge of at least one recess in an extending direction of the groove. One face of the first base material and one face of the second base material are stuck together opposite to each other to form the plurality of reaction containers and the channel.