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公开(公告)号:US09121795B2
公开(公告)日:2015-09-01
申请号:US13879995
申请日:2010-10-29
申请人: Feng Tian , Daniel Liang Zou , Lingyun Ji
发明人: Feng Tian , Daniel Liang Zou , Lingyun Ji
CPC分类号: G01N1/31 , B01L3/5025 , B01L9/52 , B01L2300/021 , C12Q1/68 , G01N35/00 , G01N35/0099 , G01N35/04 , G01N2035/0477
摘要: The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.
摘要翻译: 本发明提供用于生物样品的自动处理的装置,装置和方法。 本发明提供了在多于一个洗涤盆中用处理流体顺序处理生物样品的自动化装置和自动化方法。 在一些实施方案中,本发明提供了自动化装置和蛋白质印迹法的自动化方法。 在一些实施方案中,本发明提供了Southern印迹处理的自动化装置和自动化方法。 在一些实施方案中,本发明提供了自动化装置和Northern印迹法的自动化方法。 在一些实施方案中,本发明提供了在固体支持物上染色生物分子的自动化装置和自动化方法。 在一些实施方案中,本发明提供自动化装置和核酸分离和分离的自动化方法。
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公开(公告)号:US20060231173A1
公开(公告)日:2006-10-19
申请号:US10546471
申请日:2003-09-22
申请人: Daniel Liang , Wendy Borbidge , Daniel East , Ross Alien , David Renshaw , Colleen Bettles , Mark Gibson
发明人: Daniel Liang , Wendy Borbidge , Daniel East , Ross Alien , David Renshaw , Colleen Bettles , Mark Gibson
IPC分类号: C22C23/00
CPC分类号: C22F1/06 , B22D11/001 , B22D11/0622 , B22D11/16
摘要: A method of producing magnesium alloy strip, suitable for use in the production of magnesium alloy sheet by rolling reduction and heat treatment, involves casting magnesium alloy as strip, using a twin roll casting installation. In the casting, the thickness and temperature of the strip exiting from between rolls of the installation are controlled whereby the strip has a microstructure characterised by a primary phase having a form selected from deformed dendritic, equiaxed dendritic and a mixture of deformed and equiaxed dendritic forms. The resultant strip is amenable to production of sheet material by application of a homogenizing heat treatment followed by rolling and annealing.
摘要翻译: 一种适用于通过轧制还原和热处理生产镁合金板的镁合金带的制造方法,包括使用双辊铸造安装来铸造镁合金作为带材。 在铸造中,控制从装置的辊之间出来的带的厚度和温度,由此带具有微观结构,其特征在于主相具有选自变形的树枝状,等轴的树枝状的形状和变形和等轴的树枝状结构的混合物 。 所得到的带材适于通过均化热处理,然后进行轧制和退火来生产片材。
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3.
公开(公告)号:US09248089B2
公开(公告)日:2016-02-02
申请号:US14356387
申请日:2012-11-07
申请人: Feng Tian , Daniel Liang Zou , Lingyun Ji
发明人: Feng Tian , Daniel Liang Zou , Lingyun Ji
摘要: The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.
摘要翻译: 本公开涉及基于肽的化合物,其衍生物,药学上可接受的盐,溶剂合物和水合物。 本公开的化合物和组合物可以抑制作为皱纹治疗的神经递质释放和肌肉收缩。 本公开的化合物可用于病理性神经元胞吐作用介导的化妆品和/或治疗目的。
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公开(公告)号:US20150285790A1
公开(公告)日:2015-10-08
申请号:US14679024
申请日:2015-04-05
申请人: Feng Tian , Daniel Liang Zou , Lingyun Ji
发明人: Feng Tian , Daniel Liang Zou , Lingyun Ji
CPC分类号: G01N33/5304 , B01L1/00 , B01L3/508 , B01L3/52 , B01L2300/02 , B01L2300/0672 , B01L2300/0841 , G01N1/38 , G01N33/5302 , G01N2035/00524
摘要: The present disclosure provides an automated bioprocessing device, which may comprises a processing machine, one or more removable washing cartridges. The removable washing cartridge may comprise a shell, a sample holder, a washing basin, a waste container, a reagent container, a rotation mechanism, and a poking mechanism. The processing machine may comprise a motor, which may provide power to the inserted removable washing cartridge.
摘要翻译: 本公开提供了一种自动生物处理装置,其可以包括处理机器,一个或多个可移除的洗涤筒。 可移除的清洗盒可以包括壳体,样本保持器,洗涤盆,废物容器,试剂容器,旋转机构和戳戳机构。 加工机器可以包括电机,其可以向插入的可移除的清洗盒提供电力。
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公开(公告)号:US09945011B2
公开(公告)日:2018-04-17
申请号:US13699402
申请日:2011-05-24
申请人: Kishore Venkatesan , Wendy Elizabeth Borbidge , Michael Edward Kellam , Daniel Liang , Peter Adrian Lynch , Guangsheng Song
发明人: Kishore Venkatesan , Wendy Elizabeth Borbidge , Michael Edward Kellam , Daniel Liang , Peter Adrian Lynch , Guangsheng Song
CPC分类号: C22C23/06 , B22D21/007 , C22C23/04 , C22F1/06
摘要: An improved magnesium-based alloy for wrought applications is disclosed, including a method of fabricating alloy sheet from said alloy. The improved magnesium-based alloy consists of: 0.5 to 4.0% by weight zinc; 0.02 to 0.70% by weight a rare earth element, or mixture of the same including gadolinium; and incidental impurities. The rare earth element in some embodiments may be yttrium and/or gadolinium. In some embodiments the magnesium-based alloy may also consist of a grain refiner and in some embodiments the grain refiner may be zirconium. In combination, the inclusion of zinc and a rare earth element, into the magnesium alloy may have enhanced capacity for rolling workability, deep drawing at low temperatures and stretch formability at room temperature. The improved alloy may also exhibit increased tensile strength and formability while evincing a reduced tendency for tearing during preparation.
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公开(公告)号:US09389221B2
公开(公告)日:2016-07-12
申请号:US14679024
申请日:2015-04-05
申请人: Feng Tian , Daniel Liang Zou , Lingyun Ji
发明人: Feng Tian , Daniel Liang Zou , Lingyun Ji
CPC分类号: G01N33/5304 , B01L1/00 , B01L3/508 , B01L3/52 , B01L2300/02 , B01L2300/0672 , B01L2300/0841 , G01N1/38 , G01N33/5302 , G01N2035/00524
摘要: The present disclosure provides an automated bioprocessing device, which may comprises a processing machine, one or more removable washing cartridges. The removable washing cartridge may comprise a shell, a sample holder, a washing basin, a waste container, a reagent container, a rotation mechanism, and a poking mechanism. The processing machine may comprise a motor, which may provide power to the inserted removable washing cartridge.
摘要翻译: 本公开提供了一种自动生物处理装置,其可以包括处理机器,一个或多个可移除的洗涤筒。 可移除的清洗盒可以包括壳体,样本保持器,洗涤盆,废物容器,试剂容器,旋转机构和戳戳机构。 加工机器可以包括电机,其可以向插入的可移除的清洗盒提供电力。
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7.
公开(公告)号:US20140286885A1
公开(公告)日:2014-09-25
申请号:US14356387
申请日:2012-11-07
申请人: Feng Tian , Daniel Liang Zou , Lingyun Ji
发明人: Feng Tian , Daniel Liang Zou , Lingyun Ji
摘要: The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.
摘要翻译: 本公开涉及基于肽的化合物,其衍生物,药学上可接受的盐,溶剂合物和水合物。 本公开的化合物和组合物可以抑制作为皱纹治疗的神经递质释放和肌肉收缩。 本公开的化合物可用于病理性神经元胞吐作用介导的化妆品和/或治疗目的。
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公开(公告)号:US20130199677A1
公开(公告)日:2013-08-08
申请号:US13699402
申请日:2011-05-24
申请人: Kishore Venkatesan , Wendy Elizabeth Borbidge , Michael Edward Kellam , Daniel Liang , Peter Adrian Lynch , Guangsheng Song
发明人: Kishore Venkatesan , Wendy Elizabeth Borbidge , Michael Edward Kellam , Daniel Liang , Peter Adrian Lynch , Guangsheng Song
CPC分类号: C22C23/06 , B22D21/007 , C22C23/04 , C22F1/06
摘要: An improved magnesium-based alloy for wrought applications is disclosed, including a method of fabricating alloy sheet from said alloy. The improved magnesium-based alloy consists of: 0.5 to 4.0% by weight zinc; 0.02 to 0.70% by weight a rare earth element, or mixture of the same including gadolinium; and incidental impurities. The rare earth clement in some embodiments may be yttrium and/or gadolinium. In some embodiments the magnesium-based alloy may also consist of a grain refiner and in some embodiments the grain refiner may be zirconium. In combination, the inclusion of zinc and a rare earth element, into the magnesium alloy may have enhanced capacity for rolling workability, deep drawing at low temperatures and stretch formability at room temperature. The improved alloy may also exhibit increased tensile strength and formability while evincing a reduced tendency for tearing during preparation.
摘要翻译: 公开了一种用于锻造应用的改进的镁基合金,包括从所述合金制造合金板的方法。 改进的镁基合金由以下组成:0.5〜4.0重量%的锌; 0.02〜0.70重量%的稀土元素,或其混合物包括钆; 和杂质。 在一些实施方案中,稀土元素可以是钇和/或钆。 在一些实施方案中,镁基合金还可以由晶粒细化剂组成,并且在一些实施方案中,晶粒细化剂可以是锆。 锌合金和稀土元素组合在一起可以提高轧制加工性能,在低温下深拉伸和拉伸成形性在室温下的能力。 改进的合金还可以表现出增加的拉伸强度和成形性,同时在制备期间表现出降低的撕裂倾向。
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公开(公告)号:US20090273852A1
公开(公告)日:2009-11-05
申请号:US12434267
申请日:2009-05-01
申请人: Yuan-Hung WANG , Daniel Liang , Yih-Far Chen , Cheng-Chung Kuan , Chun-Lang Liao
发明人: Yuan-Hung WANG , Daniel Liang , Yih-Far Chen , Cheng-Chung Kuan , Chun-Lang Liao
IPC分类号: G02B5/10
CPC分类号: G02B5/10
摘要: An imaging device with micro-scale optical structures comprises a plurality of display units, where each display unit comprises a plurality of micro-scale optical structures, and each micro-scale optical structure comprises a convex part, a planar part, and base part. The convex part is positioned on the base part and has an arc surface, where the arc surface comprises a left side arc face and a right side arc face for reflecting oblique incident lights from the left or the right to form a reflected light toward the front. And different arrangements of micro-scale optical structures are used for reflecting left side and right side incident lights to display different characters or images.
摘要翻译: 具有微尺度光学结构的成像装置包括多个显示单元,其中每个显示单元包括多个微尺度光学结构,并且每个微尺度光学结构包括凸部,平面部分和基部。 凸部位于基部上并具有圆弧面,弧面包括左侧圆弧面和右侧圆弧面,用于反射左右倾斜入射光,以朝向前方形成反射光 。 并且使用微尺度光学结构的不同布置来反射左侧和右侧入射光以显示不同的字符或图像。
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公开(公告)号:US20130203072A1
公开(公告)日:2013-08-08
申请号:US13879995
申请日:2010-10-29
申请人: Feng Tian , Daniel Liang Zou , Lingyun Ji
发明人: Feng Tian , Daniel Liang Zou , Lingyun Ji
IPC分类号: G01N1/31
CPC分类号: G01N1/31 , B01L3/5025 , B01L9/52 , B01L2300/021 , C12Q1/68 , G01N35/00 , G01N35/0099 , G01N35/04 , G01N2035/0477
摘要: The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.
摘要翻译: 本发明提供用于生物样品的自动处理的装置,装置和方法。 本发明提供了在多于一个洗涤盆中用处理流体顺序处理生物样品的自动化装置和自动化方法。 在一些实施方案中,本发明提供了自动化装置和蛋白质印迹法的自动化方法。 在一些实施方案中,本发明提供了Southern印迹处理的自动化装置和自动化方法。 在一些实施方案中,本发明提供了自动化装置和Northern印迹法的自动化方法。 在一些实施方案中,本发明提供了在固体支持物上染色生物分子的自动化装置和自动化方法。 在一些实施方案中,本发明提供自动化装置和核酸分离和分离的自动化方法。
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