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    Extraction and use of collagen extracted from either a sea mammal or a bony fish
    2.
    发明申请
    Extraction and use of collagen extracted from either a sea mammal or a bony fish 审中-公开
    提取和使用从海洋哺乳动物或骨鱼提取的胶原蛋白

    公开(公告)号：US20070081961A1

    公开(公告)日：2007-04-12

    申请号：US10548520

    申请日：2004-03-10

    申请人： Adrien Beaudoin

    发明人： Adrien Beaudoin

    IPC分类号： A61K38/17 ,  C07K14/00 ,  A61K8/64 ,  C12N5/06

    CPC分类号： C12N5/0629 ,  C07K14/78 ,  C12N5/0062 ,  C12N5/0068 ,  C12N2533/54

    摘要： A process for a cell culture wherein the cells are grown on a substrate, the improvement comprising the step of growing the cells on collagen substrate with the collagen having been extracted from an animal selected from the group consisting of a marine mamal and a bony fish. Preferred embodiments include those wherein the collage is either from salmon or a seal.

    摘要翻译： 一种细胞培养方法，其中细胞在基质上生长，其改进包括使胶原蛋白从胶原基质中生长，其中所述胶原蛋白是从选自海洋哺乳动物和骨鱼的动物中提取的。 优选的实施方案包括其中拼贴是来自鲑鱼或密封的那些。

    Methods for screening for a compound useful in the treatment or prevention of lymphocytic disorders, for inhibiting lymphocite activity and preventing or treating lymphocytic disorders
    3.
    发明申请
    Methods for screening for a compound useful in the treatment or prevention of lymphocytic disorders, for inhibiting lymphocite activity and preventing or treating lymphocytic disorders 审中-公开
    用于筛选用于治疗或预防淋巴细胞病症，抑制淋巴细胞活性和预防或治疗淋巴细胞性疾病的化合物的方法

    公开(公告)号：US20050164306A1

    公开(公告)日：2005-07-28

    申请号：US10511133

    申请日：2003-04-22

    申请人： Adrien Beaudoin ,  Ouhida Benrezzak

    发明人： Adrien Beaudoin ,  Ouhida Benrezzak

    IPC分类号： C12Q1/42 ,  G01N33/53 ,  A61K31/7076 ,  G01N33/567

    CPC分类号： C12Q1/42

    摘要： A method of screening for a compound useful in the treatment of a disease or condition characterized by an immune cells disorder, wherein said cell expresses NTPDases, said method comprising the steps of contacting a candidate compound with ecto-nucleoside triphosphate diphosphohydrolase (NTPDase), wherein the candidate compound is selected if the activity of said NTPDase is reduced in the presence of the candidate compound as compared to that in the absence thereof. A method for inhibiting an immune cell activity in a mammal, comprising targeting immune cells with an effective amount of a NTPDase inhibitor. A method to prevent or reduce the risk of rejection of transplanted tissue or organ, comprising administering to said animal an effective amount of NTPDase inhibitor.

    摘要翻译： 一种筛选用于治疗以免疫细胞病症为特征的疾病或病症的化合物的方法，其中所述细胞表达NTPDases，所述方法包括使候选化合物与二磷酸核苷三磷酸二磷酸水解酶（NTPDase）接触的步骤，其中 如果在候选化合物存在下与所述候选化合物相比，所述NTPDase的活性降低，则选择候选化合物。 一种抑制哺乳动物免疫细胞活性的方法，包括用有效量的NTPDase抑制剂靶向免疫细胞。 一种防止或降低移植组织或器官排斥风险的方法，包括向所述动物施用有效量的NTPDase抑制剂。

    Method of extracting lipids from marine and aquatic animal tissues
    6.
    发明授权
    Method of extracting lipids from marine and aquatic animal tissues 有权
    从海洋和水生动物组织中提取脂质的方法

    公开(公告)号：US06800299B1

    公开(公告)日：2004-10-05

    申请号：US09830146

    申请日：2001-07-25

    申请人： Adrien Beaudoin ,  Geneviéve Martin

    发明人： Adrien Beaudoin ,  Geneviéve Martin

    IPC分类号： A61K3556

    CPC分类号： C11B1/10

    摘要： Provided herein is a method for extracting lipid fractions from marine and aquatic animal material by acetone extraction. The resulting non-soluble and particulate fraction is preferably subjected to an additional solvent extraction with an alcohol, preferably ethanol, isopropanol or t-butanol or an ester of acetic acid, preferably ethyl acetate to achieve extraction of the remaining soluble lipid fraction from the marine and aquatic animal material. The remaining non-soluble particulate contents is also recovered since it is enriched in proteins and contains a useful amount of active enzymes. Also provided herein is a krill extract.

    摘要翻译： 本文提供了通过丙酮提取从海洋和水生动物材料中提取脂质部分的方法。 所得的非溶性和微粒级分优选用醇，优选乙醇，异丙醇或叔丁醇或乙酸，优选乙酸乙酯的酯进行额外的溶剂萃取，以从海洋中提取剩余的可溶性脂质部分 和水生动物材料。 剩余的不溶性颗粒含量也被回收，因为它富含蛋白质并且含有有用量的活性酶。 本文还提供了一种磷虾提取物。

    Method for purifying marine mammal oil enriched in omega 3 fatty acids and compositions comprising same
    9.
    发明授权
    Method for purifying marine mammal oil enriched in omega 3 fatty acids and compositions comprising same 失效
    用于纯化富含ω-3脂肪酸的海洋哺乳动物油的方法及其组合物

    公开(公告)号：US06713447B2

    公开(公告)日：2004-03-30

    申请号：US10148039

    申请日：2002-10-07

    申请人： Adrien Beaudoin ,  Geneviève Martin

    发明人： Adrien Beaudoin ,  Geneviève Martin

    IPC分类号： A01N3718

    CPC分类号： A23J1/04 ,  A23D9/00 ,  A23K20/147 ,  A23L33/115 ,  C11B1/06 ,  C11B1/10 ,  C11B13/00 ,  Y02W30/74

    摘要： The present invention relates to a method for purifying marine mammal oil enriched in omega 3 fatty acids and to compositions comprising such oils. The invention also relates to a method of preparing such oils from the seal and other marine mammals. More particularly, the present invention relates to a process for the transformation of subcutaneous and muscular tissues from the seal and other marine mammals. Even more particularly, the present invention relates to a process for obtaining lipid and protein extracts from the carcasses of seal and other marine mammals and to these extracts. In addition, the invention relates to fractions obtained by the methods of the present invention and to food supplements comprising same.

    摘要翻译： 本发明涉及一种净化富含ω-3脂肪酸的海洋哺乳动物油的方法以及包含这种油的组合物。 本发明还涉及从密封件和其它海洋哺乳动物制备这种油的方法。 更具体地，本发明涉及从密封件和其他海洋哺乳动物转化皮下和肌肉组织的方法。 更具体地说，本发明涉及一种从密封和其他海洋哺乳动物的尸体和这些提取物中获得脂质和蛋白质提取物的方法。 此外，本发明涉及通过本发明的方法获得的级分和包含其的食品添加剂。