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    Heat Retention Mask and Method of Using The Same
    3.
    发明申请
    Heat Retention Mask and Method of Using The Same 审中-公开
    保温面膜及其使用方法

    公开(公告)号：US20140014101A1

    公开(公告)日：2014-01-16

    申请号：US13938899

    申请日：2013-07-10

    申请人： 12th Man Technologies, Inc.

    发明人： Alex Stenzler ,  Steve Han ,  Mei-Sheng Teng

    IPC分类号： A61F7/00 ,  A62B7/10

    CPC分类号： A61F7/0085 ,  A61F7/00 ,  A61F7/02 ,  A61F2007/0003 ,  A61F2007/0006 ,  A61F2007/0061 ,  A61F2007/0257 ,  A62B7/10 ,  A62B17/005

    摘要： A device and method for reducing heat loss in at least one region of a subject's body is described. The device includes a mask component, a heat releasing reservoir, and a conduit connecting the mask component to the heat releasing reservoir and creating an airflow path therethrough, wherein the heat releasing reservoir includes at least one air permeable region that is impermeable to condensed water. Heat loss is reduced by the subject positioning the mask over the mouth and/or nose, positioning the heat releasing reservoir over the region of the subject's body, and passing warmed air exhaled by the subject into the mask through the conduit and into the heat releasing reservoir, such that the warmed air passes through the heat releasing reservoir while retaining condensed water within the heat releasing reservoir, thereby increasing the temperature of the air surrounding the at least one region of the subject's body.

    摘要翻译： 描述了用于减少受试者身体的至少一个区域中的热损失的装置和方法。 该装置包括掩模部件，放热贮存器以及将掩模部件连接到散热贮存器并产生穿过其中的气流通道的导管，其中散热贮存器包括至少一个对冷凝水不透过的透气区域。 热量损失由被摄物体将口罩定位在嘴和/或鼻子上，将放热储存器定位在被检体的区域上，并将受试者呼出的温热空气通过导管传入面罩并进入放热 储存器，使得暖空气通过放热储存器，同时将冷凝水保持在放热储存器内，从而增加被检体的至少一个区域周围的空气的温度。

    CLOSED LOOP AIR-OXYGEN BLENDER WITH HIGH AND LOW PRESSURE AIR INLET
    4.
    发明申请
    CLOSED LOOP AIR-OXYGEN BLENDER WITH HIGH AND LOW PRESSURE AIR INLET 审中-公开
    封闭环氧气氧化剂与高低压空气入口

    公开(公告)号：US20170072158A1

    公开(公告)日：2017-03-16

    申请号：US15267266

    申请日：2016-09-16

    申请人： 12th Man Technologies, Inc.

    发明人： Steve Han ,  Alex Stenzler

    IPC分类号： A61M16/12 ,  A61M16/08 ,  A61M16/20

    CPC分类号： A61M16/125 ,  A61B5/087 ,  A61M16/024 ,  A61M16/12 ,  A61M16/203 ,  A61M16/204 ,  A61M16/208 ,  A61M2016/0021 ,  A61M2016/0039 ,  A61M2205/3334 ,  A61M2205/50

    摘要： An electronic gas blender system includes a pressurized oxygen supply connected in-line to a first proportional valve, a first check valve and a first flow sensor by a first circuit of gas lines, a pressurized air supply connected in-line to a second proportional valve, a second check valve and a second flow sensor by a second circuit of gas lines, and a port disposed between the second check valve and the second flow sensor on the second circuit of gas lines for providing airflow access to a low pressure source. The port includes a plug configured to open and close the airflow access, and a control module is electrically coupled to the first proportional valve, the first flow sensor, the second proportional valve, and the second flow sensor. The electronic gas blender system can be used to blend two high pressure gas sources under dynamic control or one high pressure and one zero or low pressure gas flow source through a slave/master relationship.

    摘要翻译： 一种电子气体搅拌器系统，包括：通过第一气体管路的电路与第一比例阀，第一止回阀和第一流量传感器串联连接的加压氧气供给装置，与第二比例阀 ，第二止回阀和第二流量传感器，以及设置在气体管线的第二回路上的第二止回阀和第二流量传感器之间的端口，用于提供气流进入低压源。 该端口包括构造成打开和关闭气流通路的插头，并且控制模块电耦合到第一比例阀，第一流量传感器，第二比例阀和第二流量传感器。 电子气体混合器系统可用于在动态控制下混合两种高压气源，或通过从属/主关系混合一个高压和一个零或低压气体流动源。

    CYSTIC FIBROSIS TREATMENT COMPRISING NITRIC OXIDE
    5.
    发明申请
    CYSTIC FIBROSIS TREATMENT COMPRISING NITRIC OXIDE 审中-公开
    包含氧化氮的CYSTIC FIBROSIS治疗

    公开(公告)号：US20160271056A1

    公开(公告)日：2016-09-22

    申请号：US15035898

    申请日：2014-12-11

    申请人： NITRIC SOLUTIONS INC. ,  12TH MAN TECHNOLOGIES, INC.

    发明人： Christopher Miller ,  Gilly Regev ,  Alex Stenzler

    IPC分类号： A61K9/00 ,  A61M16/12 ,  A61K33/00

    CPC分类号： A61K9/0073 ,  A61K9/007 ,  A61K33/00 ,  A61M16/12 ,  A61M2202/0275 ,  A61M2202/0007

    摘要： One aspect of the invention provides a method of treating a subject diagnosed with cystic fibrosis, but not having a pathological bacterial colonization in either lung. The method includes administering gaseous nitric oxide at a concentration of between about 40 ppm and about 400 ppm to the subject's lungs wherein said nitric oxide is administered by inhalation, and further wherein said nitric oxide induces conformational change in the cystic fibrosis transmembrane conductance regulator (CFTR) in the cells of the lung of the subject. Another aspect of the invention provides a kit comprising: an apparatus for administering gaseous nitric oxide to a subject and instructions for administering the gaseous nitric oxide according to one or more of the methods described herein.

    摘要翻译： 本发明的一个方面提供了一种治疗被诊断患有囊性纤维化但不在任一肺中具有病理性细菌定植的受试者的方法。 所述方法包括将浓度为约40ppm至约400ppm的气体一氧化氮施用于受试者的肺，其中所述一氧化氮通过吸入给药，并且其中所述一氧化氮诱导囊性纤维化跨膜传导调节因子（CFTR）中的构象变化 ）在受试者的肺的细胞中。 本发明的另一方面提供了一种试剂盒，其包括：根据本文所述的一种或多种方法向受试者施用气体一氧化氮的装置和用于施用气态一氧化氮的说明书。

    Gas Regulator with Integrated Sensors
    6.
    发明申请
    Gas Regulator with Integrated Sensors 审中-公开
    带集成传感器的气体调节器

    公开(公告)号：US20140130799A1

    公开(公告)日：2014-05-15

    申请号：US14075402

    申请日：2013-11-08

    申请人： 12th Man Technologies, Inc.

    发明人： Alex Stenzler ,  Steve Han

    IPC分类号： A61M16/00 ,  A61M16/20 ,  A61M16/12

    CPC分类号： A61M16/0051 ,  A61M16/024 ,  A61M16/12 ,  A61M16/20 ,  A61M2016/0027 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/6018 ,  A61M2205/6054 ,  A61M2205/8206 ,  F17C13/04 ,  F17C2201/0109 ,  F17C2201/032 ,  F17C2201/056 ,  F17C2201/058 ,  F17C2205/0329 ,  F17C2205/0338 ,  F17C2205/0382 ,  F17C2205/0394 ,  F17C2205/058 ,  F17C2221/011 ,  F17C2221/03 ,  F17C2250/034 ,  F17C2270/025

    摘要： A gas regulator is described. The gas regulator includes a gas inlet having an attachment mechanism for attaching to a gas container, a gas outlet in fluid communication with the gas inlet and further in fluid communication with a gas delivery system, a pressure regulator, a pressure sensor and a NFC sensor. A method of entering at least one information item relating to a gas source to a gas delivery system control unit. The method includes the steps of providing a gas source having a NFC tag that includes at least one information item stored in a memory of the NFC tag, attaching a regulator that includes a NFC sensor, wherein the NFC sensor is positioned to read the NFC tag when attached to the gas source, reading the at least one information item via the NFC sensor, and transmitting the at least one information item read by the NFC sensor to a gas delivery system control unit.

    摘要翻译： 描述了气体调节器。 气体调节器包括气体入口，其具有用于附接到气体容器的附接机构，与气体入口流体连通并进一步与气体输送系统，压力调节器，压力传感器和NFC传感器流体连通的气体出口 。 将与气体源相关的至少一个信息项目输入到气体输送系统控制单元的方法。 该方法包括以下步骤：提供具有NFC标签的气源，所述NFC标签包括存储在NFC标签的存储器中的至少一个信息项，附接包括NFC传感器的调节器，其中NFC传感器被定位成读取NFC标签 当附接到气源时，经由NFC传感器读取至少一个信息项，并且将由NFC传感器读取的至少一个信息项发送到气体输送系统控制单元。

    Oral Appliance Monitor and Method of Using the Same
    8.
    发明申请
    Oral Appliance Monitor and Method of Using the Same 审中-公开
    口腔监护仪及其使用方法

    公开(公告)号：US20140350354A1

    公开(公告)日：2014-11-27

    申请号：US13960239

    申请日：2013-08-06

    申请人： 12th Man Technologies, Inc.

    发明人： Alex Stenzler ,  William Ross ,  Steve Han ,  Jeffory Wyscarver

    IPC分类号： A61B5/00 ,  A61F5/56 ,  A61B7/00 ,  A61B5/113 ,  A61B5/087 ,  A61B5/01

    CPC分类号： A61B5/4818 ,  A61B5/01 ,  A61B5/087 ,  A61B5/113 ,  A61B5/6814 ,  A61B7/003 ,  A61F5/566

    摘要： An oral appliance assembly is described. The assembly includes an oral appliance component having an upper teeth tray and a lower teeth tray. The assembly further includes a module releasably connected to the oral appliance. The module includes at least one sensor that is positioned outside of the mouth and underneath the nares of a subject's nose when the oral appliance component is positioned in the subject's mouth. A method of measuring user compliance of an oral appliance is also described. The method includes positioning an oral appliance in the mouth of a subject, measuring at least one parameter of airflow from the subject's nose or mouth, and determining compliance based on the at least one measured parameter. A method of measuring effectiveness of an oral appliance is also described. The method includes positioning an oral appliance in the mouth of a subject, measuring at least one parameter of airflow from the subject's nose or mouth, and determining effectiveness based on the at least one measured parameter.

    摘要翻译： 描述了口腔器具组件。 组件包括具有上齿盘和下齿盘的口腔器具部件。 组件还包括可释放地连接到口腔器具的模块。 该模块包括至少一个传感器，当口腔器具部件位于受试者的嘴中时，该传感器位于受试者鼻部的鼻孔之下。 还描述了一种测量口腔器具的用户符合性的方法。 该方法包括将口腔器具定位在受试者的口中，测量来自受试者的鼻子或嘴部的气流的至少一个参数，以及基于至少一个测量参数确定顺应性。 还描述了一种测量口腔器具有效性的方法。 该方法包括将口腔器具定位在受试者的嘴中，测量来自受试者的鼻子或嘴部的气流的至少一个参数，以及基于至少一个测量参数确定有效性。

    BRUXISM GUARD WITH MANDIBLE COMPENSATION MECHANISM
    10.
    发明申请
    BRUXISM GUARD WITH MANDIBLE COMPENSATION MECHANISM 审中-公开
    具有无偿补偿机制的BRUXISM GUARD

    公开(公告)号：US20160095741A1

    公开(公告)日：2016-04-07

    申请号：US14873464

    申请日：2015-10-02

    申请人： 12th Man Technologies, Inc. ,  DDME Inc.

    发明人： Alex Stenzler ,  William Ross ,  Jeffory Wyscarver ,  Steve Han

    IPC分类号： A61F5/56

    CPC分类号： A61F5/566 ,  A61F2005/563

    摘要： A bruxism guard is described. The bruxism guard includes a first U shaped tray having a top surface and a bottom surface, the top surface including a trough with a dental insert positioned therein, wherein the dental insert substantially conforms to a full arch of a subject's teeth, and a second U shaped tray having a top surface and a bottom surface, the top surface including a trough with a dental insert positioned therein, wherein the dental insert substantially conforms to a only a partial arch of the subject's teeth, wherein the bottom surfaces of the first and second trays oppose each other when positioned within the subject's mouth. Also described is a bruxism guard having a removable T-Bar that permits the bruxism guard to be interlocked in at least four different configurations.

    摘要翻译： 描述了一个磨牙师。 磨牙防护装置包括具有顶表面和底表面的第一U形托盘，所述顶表面包括槽，位于其中的牙科镶嵌件，其中所述牙科镶嵌件基本上符合受检者牙齿的整个拱形，第二U形 所述托盘具有顶表面和底表面，所述顶表面包括槽，所述槽具有定位在其中的牙科镶嵌件，其中所述牙科镶嵌件基本上符合所述受试者的牙齿的仅部分弓形，其中所述第一和第二 定位在受试者口中时，托盘相互对抗。 还描述了一种具有可拆卸T型杆的磨牙防护装置，其允许磨牙防护装置以至少四种不同的构造互锁。