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公开(公告)号：US11534756B2
公开(公告)日：2022-12-27
申请号：US16355462
申请日：2019-03-15
发明人： Robert Turner , James Madsen , Kai Yang , Juan Pablo Hinestrosa Salazar , Rajaram Krishnan , Pedro David Simon Herrera
IPC分类号： B01L3/00
摘要： Disclosed are cartridge components, cartridges, systems, and methods for isolating analytes from biological samples. In various aspects, the cartridge components, cartridges, systems, and methods may allow for a rapid procedure that requires a minimal amount of material from complex fluids.
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公开(公告)号：US20210214798A1
公开(公告)日：2021-07-15
申请号：US16955732
申请日：2018-12-19
IPC分类号： C12Q1/6886 , C12Q1/6806 , C12Q1/6883
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US20210146378A1
公开(公告)日：2021-05-20
申请号：US17045146
申请日：2019-04-01
发明人： Juan Pablo HINESTROSA SALAZAR , Rajaram KRISHNAN , Scott CONRADSON , Tyler Lee HARRIS , Robert Paul TURNER , George Maroor THOMAS
摘要： The present disclosure describes methods, devices and systems comprising materials comprising dielectrics. In various aspects, electrodes layered or imbedded with these dielectrics provide enhanced properties for a wide range of applications, such as the enhanced separation of analytes, such as biological molecules or particles (nucleic acids, viruses) with an electrokinetic field.
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公开(公告)号：US09682385B2
公开(公告)日：2017-06-20
申请号：US15171876
申请日：2016-06-02
发明人： David Charlot , Juan Pablo Hinestrosa Salazar , Irina V. Dobrovolskaya , Kai Yang , Paul Swanson , Rajaram Krishnan
IPC分类号： G01N27/447 , B03C5/00 , B03C5/02
CPC分类号： B03C5/005 , B03C5/026 , B03C2201/26
摘要： The present invention includes methods, devices and systems for isolating nanoparticulates, including nucleic acids, from biological samples. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity isolation of biological components from complex fluids such as blood or environmental samples.
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公开(公告)号：US08969059B2
公开(公告)日：2015-03-03
申请号：US14194572
申请日：2014-02-28
发明人： Rajaram Krishnan , David Charlot , Eugene Tu , James McCanna , Lucas Kumosa , Paul Swanson , Robert Turner , Kai Yang , Irina Dobrovolskaya , David Liu
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US08871481B2
公开(公告)日：2014-10-28
申请号：US14271337
申请日：2014-05-06
发明人： Rajaram Krishnan , David Charlot , Eugene Tu , James McCanna , Lucas Kumosa , Paul Swanson , Robert Turner , Kai Yang , Irina Dobrovolskaya , David Liu
IPC分类号： C12N13/00 , G01N27/447
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US20140127697A1
公开(公告)日：2014-05-08
申请号：US14067841
申请日：2013-10-30
发明人： Rajaram KRISHNAN , David CHARLOT , Eugene TU , James MCCANNA , Lucas KUMOSA , Paul SWANSON , Robert TURNER , Kai YANG , Irina DOBROVOLSKAYA , David LIU
IPC分类号： C12N15/10
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US20240253057A1
公开(公告)日：2024-08-01
申请号：US18542486
申请日：2023-12-15
发明人： Juan Pablo HINESTROSA SALAZAR , Rajaram KRISHNAN , Scott CONRADSON , Tyler Lee HARRIS , Robert Paul TURNER , George Maroor THOMAS
CPC分类号： B03C5/005 , B03C5/026 , B03C2201/26
摘要： The present disclosure describes methods, devices and systems comprising materials comprising dielectrics. In various aspects, electrodes layered or imbedded with these dielectrics provide enhanced properties for a wide range of applications, such as the enhanced separation of analytes, such as biological molecules or particles (nucleic acids, viruses) with an electrokinetic field.
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公开(公告)号：US10818379B2
公开(公告)日：2020-10-27
申请号：US15974591
申请日：2018-05-08
发明人： Rajaram Krishnan , Iryna Clark , Robert Turner , Robert Kovelman , Juan Pablo Hinestrosa Salazar , David Liu
摘要： Systems, devices, media, methods, and kits are disclosed to integrate and exchange information of analyte analysis kits. Analyte analysis can be performed and presented using in association with advertising or questions.
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公开(公告)号：US10232369B2
公开(公告)日：2019-03-19
申请号：US15469406
申请日：2017-03-24
发明人： Robert Turner , James Madsen , Kai Yang , Juan Pablo Hinestrosa Salazar , Raj Krishnan , Pedro David Simon Herrera
摘要： Disclosed are cartridge components, cartridges, systems, and methods for isolating analytes from biological samples. In various aspects, the cartridge components, cartridges, systems, and methods may allow for a rapid procedure that requires a minimal amount of material from complex fluids.
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