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    Spectrofluorometer
    83.
    发明授权
    Spectrofluorometer 失效
    分光光度计

    公开(公告)号：US5500536A

    公开(公告)日：1996-03-19

    申请号：US215233

    申请日：1994-03-21

    Applicant: Taro Nogami ,  Shunichi Matsuura ,  Akira Kuroda

    Inventor： Taro Nogami ,  Shunichi Matsuura ,  Akira Kuroda

    IPC: G01N21/64 ,  G01N21/01

    CPC classification number: G01N21/645 ,  G01N2021/6482 ,  G01N2201/0642

    Abstract: A fluorescence output port sandwiched between light-shielding members of a sample cell is provided at a position corresponding to an entrance slit of a fluorescence monochromator and an excitation light side port of the sample cell is provided at a position corresponding to an exit slit of an excitation side monochromator.

    Abstract translation: 夹在样品池的遮光构件之间的荧光输出端口设置在与荧光单色仪的入口狭缝相对应的位置，并且样品池的激发光侧端口设置在对应于 激发侧单色仪。

    High efficiency fluorescence flow cell for capillary liquid chromatography or capillary electrophoresis
    84.
    发明授权
    High efficiency fluorescence flow cell for capillary liquid chromatography or capillary electrophoresis 失效
    用于毛细管液相色谱或毛细管电泳的高效荧光流通池

    公开(公告)号：US5430541A

    公开(公告)日：1995-07-04

    申请号：US3351

    申请日：1993-01-12

    Applicant: Edwin Sapp ,  Robert Weinberger

    Inventor： Edwin Sapp ,  Robert Weinberger

    IPC: G01N21/03 ,  G01N21/05 ,  G01N21/64 ,  G01N30/74

    CPC classification number: G01N21/0303 ,  G01N21/05 ,  G01N21/645 ,  G01N2021/0346 ,  G01N2021/6482 ,  G01N21/64 ,  G01N2201/0642 ,  G01N30/74

    Abstract: A fluorescence flow cell having a capillary through which a sample fluid is moved, an optical source that directs an exposing beam of light through the sample fluid, a collector that collects fluorescent light from the exposed region of the sample and directs such collected light to a detector. A beam blocker prevents light that is scattered by the capillary walls from reaching the detector, thereby improving the signal-to-noise ratio of the system. The beam blocker also has a pair of legs that prevent the sample fluid from being exposed by either the exposing light or the collected light outside of the exposing region. The structure of the components enables the various components to be quickly and accurately assembled and enables easy replacement of the capillary.

    Abstract translation: 具有毛细管的荧光流通池，样品流体通过其移动，将曝光光束引导通过样品流体的光源，收集来自样品的暴露区域的荧光的收集器，并将这种收集的光引导到 探测器。 光束阻挡器防止毛细管壁散射的光到达检测器，从而提高系统的信噪比。 光束阻挡器还具有一对腿，其防止样品流体暴露于曝光区域外的曝光光或收集的光。 组件的结构使得能够快速且准确地组装各种部件，并且能够容易地更换毛细管。

    Spectral-band filtration spectrometry apparatus
    85.
    发明授权
    Spectral-band filtration spectrometry apparatus 失效
    光谱带过滤光谱仪

    公开(公告)号：US5424825A

    公开(公告)日：1995-06-13

    申请号：US953887

    申请日：1992-09-30

    Applicant: Michel Delhaye ,  Edouard Da Silva ,  Gerard Martinez

    Inventor： Michel Delhaye ,  Edouard Da Silva ,  Gerard Martinez

    IPC: G01J3/02 ,  G01J3/18 ,  G01J3/44 ,  G02B5/00 ,  G01J3/30

    CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0262 ,  G01J3/44 ,  G02B5/005 ,  G01J2003/1814 ,  G01N2021/6417 ,  G01N2201/0642

    Abstract: The filtration means filter the exciter radiation (EX) in a first forward direction from generator means (LS) to the specimen (EC), by allowing a second spectral band (BZ) of predetermined spectral width (l) and centered on a selected frequency corresponding to the wavelength of the exciter radiation (L0) to pass and stopping a first spectral band (FZ) complementary to the second spectral band (BZ), while substantially simultaneously with this first filtration operation, these filtration means further filter the analysis radiation (ON) in a second direction that is the reverse of the first direction, by allowing the first spectral band (FZ) to pass and stopping the second spectral band (BZ).

    Abstract translation: 过滤装置通过允许预定光谱宽度（l）的第二光谱带（BZ）并以选定频率为中心，将激发器辐射（EX）从发生器装置（LS）向第一正向过滤到样品（EC） 对应于通过和停止与第二光谱带（BZ）互补的第一光谱带（FZ）的激发器辐射（L0）的波长，同时基本上同时进行第一过滤操作，这些过滤装置进一步过滤分析辐射 ON）通过使第一光谱带（FZ）通过并停止第二光谱带（BZ）而在与第一方向相反的第二方向上。

    Sample container for laser light scattering photometers
    88.
    发明授权
    Sample container for laser light scattering photometers 失效
    激光光散射测光仪样品容器

    公开(公告)号：US3843268A

    公开(公告)日：1974-10-22

    申请号：US37689873

    申请日：1973-07-05

    Applicant: BECKMAN INSTRUMENTS INC

    Inventor： KAYE W

    IPC: G01N21/03 ,  G01N21/51 ,  G01N1/10

    CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N2201/0642

    Abstract: In a laser photometer for measuring radiant power scattered from a sample at a selectable, small forward angle with respect to the direction of an incident beam of radiant power, there is disclosed an improved sample container comprising first and second thick, transparent windows; a spacer between the windows having first and second coaxial, intersecting passageways therein, the beam from the laser entering the first window and the first passageway and the scattered radiant power exiting through the second passageway and the second window; and a black glass disc positioned at the intersection of the passageways, the disc having an aperture therein forming a cell for the sample which is coaxial with the first and second passageways, the laser beam being focused in the aperture, the disc operating to absorb light scattered from the second window thereby reducing background scattering and the usable scattering angle of the photometer.

    Devices and methods for imaging microarray chips
    90.
    发明授权
    Devices and methods for imaging microarray chips 有权

    公开(公告)号：US12031912B2

    公开(公告)日：2024-07-09

    申请号：US17607761

    申请日：2020-05-02

    Applicant: Duke University

    Inventor： Jason Liu ,  Ashutosh Chilkoti

    IPC: G01N21/64

    CPC classification number: G01N21/6452 ,  G01N21/6402 ,  G01N21/6428 ,  G01N21/6456 ,  G01N2021/6439 ,  G01N2201/022 ,  G01N2201/06113 ,  G01N2201/0642

    Abstract: A microarray chip imaging detector comprises a housing configured to receive a microarray chip. The detector includes a laser assembly supported by the housing and oriented at an angle relative to the microarray chip, the laser assembly configured to transmit an excitation beam along a first axis to samples on the microarray chip. The detector also includes a camera supported by the housing and positioned along a second axis, the camera configured to receive fluorescent light emitted from fluorophores in the samples on the microarray chip, the second axis oriented at an angle less than 30 degrees relative to the first axis. The housing includes a plurality of baffles positioned between the microarray chip and the camera, and a plurality of laser beamstops to receive the excitation beam reflected off the microarray chip.

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