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公开(公告)号：US20240345092A1
公开(公告)日：2024-10-17
申请号：US18682668
申请日：2022-08-10
Applicant: RANDOX LABORATORIES LTD.
Inventor： Stephen Peter Fitzgerald , Mark Ruddock , John Lamont , Declan McKenna
IPC: G01N33/574
CPC classification number: G01N33/57434 , G01N33/57488
Abstract: Single markers lack both sensitivity and specificity to stratify risk of PCa in patients who present with elevated tPSA and abnormal DRE. The novel combination of serum markers identified in this study could be employed to help triage patients into ‘low’ and ‘high’ risk categories, allowing general practitioners (GPs) to improve management of patients in primary care settings and potentially reducing the number of referrals for unnecessary, invasive, and costly treatments.
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公开(公告)号：US20220341943A1
公开(公告)日：2022-10-27
申请号：US17765383
申请日：2020-10-07
Applicant: Randox Laboratories Ltd , Randox Teoranta
Inventor： Ivan McConnell , Peter Fitzgerald , Ciaran Richardson , Kenneth Martin
IPC: G01N33/68 , G01N33/50 , G01N33/543
Abstract: Methods, devices and kits for the detection and quantification of XBP1s and XBP1u are described.
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公开(公告)号：US11467163B2
公开(公告)日：2022-10-11
申请号：US16065646
申请日：2016-12-23
Applicant: Randox Laboratories Ltd. , Randox Teoranta
Inventor： Ivan McConnell , Peter Fitzgerald , John Lamont , Ciaran Richardson
IPC: G01N33/574
Abstract: The present invention describes methods of determining the glycosylation signature and determining the level of a protein in a sample obtained from a patient.
The present invention also describes use of a patient protein glycosylation profile to identify the presence or absence of a disease in subjects.-
公开(公告)号：US11383216B2
公开(公告)日：2022-07-12
申请号：US16424330
申请日：2019-05-28
Applicant: Randox Laboratories Ltd. , Randox Teoranta
Inventor： Peter Fitzgerald , John Lamont , Ivan McConnell , Elouard Benchikh , Deepesh Upadhyay , Ciaran Richardson
IPC: B01J19/00 , C09D11/102 , C09D11/03 , G01N33/543 , C12M1/00
Abstract: A substrate comprising a coating of a masking material, and a plurality of discrete reaction zones onto which one or more binding agents are intended to be attached, wherein said zones are uncoated areas on the substrate.
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公开(公告)号：US20220160921A1
公开(公告)日：2022-05-26
申请号：US17602853
申请日：2020-04-09
Applicant: RANDOX LABORATORIES LTD
Inventor： Catherine McCooke , Peter Fitzgerald
Abstract: There is provided a sterilisation monitoring device for a molecular diagnostics analyser. The device comprises a sensor arranged in use to detect radiation; and an analysis unit connected to the sensor. The analysis unit is arranged in use to issue a signal when the radiation level incident on the sensor is lower than a threshold level.
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Patent Agency Ranking
公开(公告)号：US20220152244A1
公开(公告)日：2022-05-19
申请号：US17602831
申请日：2020-04-09
Applicant: RANDOX LABORATORIES LTD
Inventor： Peter Fitzgerald , David Sloan , Martin Reid , Stuart Jackson
Abstract: There is provided a sterilisation assembly for a molecular diagnostic assay analyse. The assembly comprising: an enclosure having a passage therethrough, the passage being arranged in use to allow an assay sample set to pass through the enclosure, the enclosure defining a barrier adapted in use to restrict fluid communication across the enclosure to communication through the passage; and a decontaminator located within the passage, the decontaminator is arranged in use to sterilise contamination in the passage.
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公开(公告)号：US20210018515A1
公开(公告)日：2021-01-21
申请号：US17040016
申请日：2019-03-22
Inventor： Mary Jo KURTH , John LAMONT , Peter FITZGERALD , Mark RUDDOCK , William MCBRIDE
IPC: G01N33/68
Abstract: A method for determining predisposition of a subject to developing renal dysfunction (AKI), and to a kit for use in making such a determination is provided. Suitably at least one marker selected from Midkine (MK) or H-FABP present in a blood or urine sample is used in the method.
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公开(公告)号：US10815192B2
公开(公告)日：2020-10-27
申请号：US15903361
申请日：2018-02-23
Applicant: Randox Laboratories Ltd.
Inventor： Ivan McConnell , Peter Fitzgerald , Elouard Benchikh , Philip Lowry
Abstract: Antibodies, immunoassay methods and kits for the detection and determination of 3,4,-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide and 3,4,-dichloro-N-[2-(methylamino)cyclohexyl]-N-methylbenzamide, as well as the precursory immunogens, are described.
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公开(公告)号：US20190293662A1
公开(公告)日：2019-09-26
申请号：US16462924
申请日：2017-11-23
Applicant: Randox Laboratories Ltd , Randox Teoranta
Inventor： Ciaran Richardson , Ivan McConnell , John Lamont , Stephen Peter Fitzgerald
Abstract: Described are methods and kits for diagnosing stroke using GFAP derivatives.
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公开(公告)号：US10168331B2
公开(公告)日：2019-01-01
申请号：US15304473
申请日：2015-04-02
Applicant: Randox Laboratories Ltd.
Inventor： Mark Ruddock , Cherith Reid , John Lamont , Stephen Fitzgerald , Ricardo De Matos Simoes , Kathleen Williamson
IPC: G01N33/574 , G01N33/68 , G01N33/543 , G01N33/577
Abstract: The present invention provides a method and a solid state device for identifying the presence of urothelial cancer in a patient comprising assigning the subject to a sub-population according to smoking habits, measuring the level of each biomarker of a panel of biomarkers in one or more samples obtained from the subject; and correlating the measured levels of the panel of biomarkers with the likelihood of the subject having urothelial cancer such that the subject can be classified as having urothelial cancer or as being a control.
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