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71.发明申请公开(公告)号：US20170165362A1
公开(公告)日：2017-06-15
申请号：US15332495
申请日：2016-10-24
Applicant: aTyr Pharma, Inc. , Pangu BioPharma Limited
Inventor： Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain P. Vasserot , Wing-Sze Lo , Jeffry D. Watkins , Cheryl L. Quinn , John D. Mendlein
IPC: A61K39/395 , A61K9/19
CPC classification number: A61K39/3955 , A61K9/19 , A61K38/00 , A61K38/53 , A61K2039/505 , A61K2121/00 , C07K16/40 , C07K2319/00 , C12N9/1085 , C12N9/93 , C12Y601/01 , G01N33/573 , G01N2333/9015
Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
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公开(公告)号：US09623093B2
公开(公告)日：2017-04-18
申请号：US14620548
申请日：2015-02-12
Applicant: aTyr Pharma, Inc. , Pangu BioPharma Limited
Inventor： Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain P. Vasserot , Wing-Sze Lo , Jeffry D. Watkins , Cheryl L. Quinn , John D. Mendlein
IPC: C07K14/47 , C07K14/35 , A61K38/53 , C12N9/10 , C12N9/00 , G01N33/50 , G01N33/68 , C12N9/96 , A61K35/12 , C07K14/00 , G01N33/573 , A61K38/00
CPC classification number: C07K16/40 , A61K35/12 , A61K38/00 , A61K38/53 , C07K14/00 , C07K2317/24 , C07K2317/34 , C07K2319/33 , C12N9/1085 , C12N9/93 , C12N9/96 , C12Y601/01 , G01N33/5008 , G01N33/573 , G01N33/68 , G01N2333/9015 , G01N2500/00
Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
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73.发明申请INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF ASPARTYL-TRNA SYNTHETASES 审中-公开与ASPARTYL-TRNA合成蛋白片段相关的治疗，诊断和抗体组合物的创新发现公开(公告)号：US20170002091A1
公开(公告)日：2017-01-05
申请号：US15067645
申请日：2016-03-11
Applicant: aTyr Pharma Inc. , Pangu BioPharma Limited
Inventor： Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain P. Vasserot , Wing-Sze Lo , Jeffry Watkins , Cheryl L. Quinn , John D. Mendlein
IPC: C07K16/40
CPC classification number: C12N9/93 , A61K38/00 , A61K38/53 , C07K16/40 , C07K2317/24 , C07K2317/92 , C07K2319/00 , C12Y601/01 , G01N33/573 , G01N2333/9015
Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
Abstract translation: 提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，编码它们的多核苷酸及其补体，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。
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公开(公告)号：US09528103B2
公开(公告)日：2016-12-27
申请号：US14593613
申请日：2015-01-09
Applicant: aTyr Pharma Inc. , Pangu Biopharma Limited
Inventor： Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain P. Vasserot , Wing-Sze Lo , Jeffry D. Watkins , Cheryl L. Quinn , John D. Mendlein
IPC: C07K16/40 , C12N9/00 , G01N33/573 , A61K38/00
CPC classification number: C07K16/40 , A61K38/00 , A61K39/39591 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/34 , C07K2317/92 , C07K2319/00 , C12N9/93 , C12Y601/01 , C12Y601/01005 , G01N33/573 , G01N2333/9015
Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
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75.发明授权Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-trna synthetases 有权与酪氨酰-tRNA合成酶的蛋白质片段相关的治疗，诊断和抗体组合物的创新发现公开(公告)号：US09428743B2
公开(公告)日：2016-08-30
申请号：US14684052
申请日：2015-04-10
Applicant: aTyr Pharma, Inc. , Pangu BioPharma Limited
Inventor： Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain Philippe Vasserot , Wing-Sze Lo , Jeffry D. Watkins , Cheryl L. Quinn , John D. Mendlein
IPC: C07K16/40 , G01N33/573 , A61K38/16 , A61K38/00 , C12N9/00
CPC classification number: C07K16/40 , A61K38/00 , A61K38/16 , C07K2317/24 , C07K2317/622 , C07K2317/92 , C12N9/93 , C12Y601/01 , C12Y601/01001 , G01N33/573 , G01N2333/9015
Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
Abstract translation: 提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，编码它们的多核苷酸及其补体，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。
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Patent Agency Ranking
76.发明授权Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl tRNA synthetases 有权与丙氨酰tRNA合成酶的蛋白质片段相关的治疗，诊断和抗体组合物的创新发现公开(公告)号：US09320782B2
公开(公告)日：2016-04-26
申请号：US14620817
申请日：2015-02-12
Applicant: aTyr Pharma, Inc. , Pangu BioPharma Limited
Inventor： Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain P. Vasserot , Wing-Sze Lo , Jeffry D. Watkins , Cheryl L. Quinn , John D. Mendlein
IPC: C12N9/00 , C12N15/00 , A61K38/53 , C12N9/18 , G01N33/50 , G01N33/68 , C07K16/40 , C12N5/071 , C12N9/96 , A61K35/12 , C07K14/00 , G01N33/573 , A61K38/00
CPC classification number: C07K16/40 , A61K35/12 , A61K38/00 , A61K38/53 , C07K14/00 , C07K2317/24 , C07K2317/622 , C07K2319/33 , C12N5/0602 , C12N9/18 , C12N9/93 , C12N9/96 , C12Y601/01 , C12Y601/01007 , G01N33/5008 , G01N33/573 , G01N33/68 , G01N2333/9015 , G01N2500/00
Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
Abstract translation: 提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，编码它们的多核苷酸及其补体，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。
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77.发明申请INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF HISTIDYL-TRNA SYNTHETASES 有权与HISTIDYL-TRNA合成蛋白片段相关的治疗，诊断和抗体组合物的创新发现公开(公告)号：US20150344866A1
公开(公告)日：2015-12-03
申请号：US14675343
申请日：2015-03-31
Applicant: aTyr Pharma, Inc. , Pangu BioPharma Limited
Inventor： Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain P. Vasserot , Wing-Sze Lo , Jeffry D. Watkins , Cheryl L. Quinn , John D. Mendlein
IPC: C12N9/00
CPC classification number: C12N9/93 , A61K38/00 , A61K38/53 , C07K16/40 , C12N5/0602 , C12N9/96 , C12Y601/01 , C12Y601/01021 , G01N33/68
Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
Abstract translation: 提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，编码它们的多核苷酸及其补体，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。
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78.发明申请INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF LYSYL-TRNA SYNTHETASES 有权与LYSYL-TRNA合成蛋白片段相关的治疗，诊断和抗体组合物的创新发现公开(公告)号：US20150252347A1
公开(公告)日：2015-09-10
申请号：US14592431
申请日：2015-01-08
Applicant: aTyr Pharma Inc. , Pangu Biopharma Limited
Inventor： Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain P. Vasserot , Wing-Sze Lo , Jeffry D. Watkins , Cheryl L. Quinn , John D. Mendlein
IPC: C12N9/00 , G01N33/573 , C07K16/40 , C12N9/96
CPC classification number: C07K16/40 , A61K38/00 , C07K2317/24 , C07K2317/622 , C12N5/0602 , C12N9/93 , C12N9/96 , C12Y601/01 , C12Y601/01007 , G01N33/573 , G01N33/68 , G01N2333/9015
Abstract: Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
Abstract translation: 提供了包含新确定的氨酰-tRNA合成酶的蛋白质片段的组合物，编码它们的多核苷酸及其补体，相关试剂及其在诊断，药物发现，研究和治疗应用中的使用方法。
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79.发明授权公开(公告)号：US09896680B2
公开(公告)日：2018-02-20
申请号：US14703627
申请日：2015-05-04
Applicant: aTyr Pharma, Inc.
Inventor： Ryan A. Adams , Fei Hong , Ji Zhao , Kristi Piehl , Eva R. Armour , Kenny D'Arigo , Leslie A. Greene , Eve Merriman
IPC: A61K38/00 , C12N9/00 , C12Q1/25 , G01N33/573 , C07K16/00
CPC classification number: C12N9/93 , A61K38/00 , C07K16/00 , C07K2319/30 , C07K2319/33 , C12Q1/25 , C12Y601/01012 , G01N33/573 , G01N2500/00 , Y02A50/385 , Y02A50/389 , Y02A50/411 , Y02A50/423 , Y02A50/463 , Y02A50/53 , Y02A50/58
Abstract: Isolated aspartyl-tRNA synthetase polypeptides and polynucleotides having non-canonical biological activities are provided, as well as compositions and methods related thereto.
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80.发明授权Compositions and methods comprising glycyl-tRNA synthetases having non-canonical biological activities 有权包含具有非规范生物活性的甘氨酰-tRNA合成酶的组合物和方法公开(公告)号：US09157076B2
公开(公告)日：2015-10-13
申请号：US14262247
申请日：2014-04-25
Applicant: aTyr Pharma, Inc.
Inventor： Leslie Ann Greene , Ryan Andrew Adams , Fei Hong , Ji Zhao , Eva Rebecka Stephanie Armour , Kristi Helen Piehl
CPC classification number: A61K38/53 , C07K1/14 , C12N9/93 , C12N9/96 , C12N15/102 , C12Y601/01014
Abstract: Isolated glycyl-tRNA synthetase polypeptides and polynucleotides having non-canonical biological activities are provided, as well as compositions and methods related thereto.
Abstract translation: 提供了分离的甘氨酰-tRNA合成酶多肽和具有非规范生物学活性的多核苷酸，以及与其相关的组合物和方法。
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