公开(公告)号：US20070196913A1

公开(公告)日：2007-08-23

申请号：US11357592

申请日：2006-02-18

申请人： Stephen Chen

发明人： Stephen Chen

IPC分类号： C12M1/22

CPC分类号： C12M23/20 ,  C12M23/10 ,  C12M23/32 ,  G02B21/34

摘要： An improvement made to cell culture plates and dishes. The plastic bottom is made detachable for slides without using glass for cell culture. To detach a plate bottom, the user inserts a key to the plate and makes a 90-degree turn, which breaks a detaching ring and releases the plastic bottom as a circular disc with attached cells on it.

摘要翻译： 对细胞培养板和菜肴进行了改进。 塑料底部是可拆卸的幻灯片，而不使用玻璃细胞培养。 为了拆下钢板底部，用户将一个钥匙插入板上并进行90度转动，这会打破一个拆卸环，并将塑料底部作为一个带有连接细胞的圆盘释放。

公开(公告)号：US20070082390A1

公开(公告)日：2007-04-12

申请号：US11532688

申请日：2006-09-18

申请人： Abel Z. Hastings ,  Neil Robbins

发明人： Abel Z. Hastings ,  Neil Robbins

IPC分类号： C12M1/22 ,  C12M1/34

CPC分类号： C12M25/14 ,  B01L3/5085 ,  B01L3/50855 ,  B01L2300/0609 ,  B01L2300/0829 ,  C12M23/12

摘要： A scaffold handling system comprising a multi-well carrier including an array of well units wherein, in each well unit, an independent scaffold or tissue slice may be held and a biological experiment may be performed. The carrier may include any number of well units. In operation, the scaffold handling system is configured and dimensioned to mate with a multi-well plate.

摘要翻译： 一种支架处理系统，其包括多孔载体，所述多孔载体包括孔阵列阵列，其中在每个孔单元中可以保持独立的支架或组织切片并且可以进行生物学实验。 承运人可以包括任何数量的井单元。 在操作中，脚手架处理系统的构造和尺寸被设计成与多孔板相配合。

公开(公告)号：US20070015277A1

公开(公告)日：2007-01-18

申请号：US11446913

申请日：2006-06-05

申请人： Hideshi Hattori ,  Masatoshi Kuroda

发明人： Hideshi Hattori ,  Masatoshi Kuroda

IPC分类号： C12N5/06 ,  C12M1/22

CPC分类号： C12N5/0068 ,  C12N2533/30

摘要： A main object of the present invention is to provide a cell transfer substrate capable of transplanting cells, maintaining a pattern as it is, on a living body tissue or the like, even when: the size of the cell sheet is extremely small; the cells are cultured sparsely; the cells are in a form of a small colony; or the cells are cultured in a pattern, for example, as a blood vessel, a vessel network such as a lymphatic vessel, or a nerve network, and to provide a substrate for cell transfer to be used for the cell transfer substrate. In order to achieve the above-mentioned object, the present invention provides a substrate for cell transfer comprising: a polymer base material; an intermediate layer formed on the polymer base material; and a cell transfer layer formed on the intermediate layer.

摘要翻译： 本发明的主要目的在于，提供一种能够将细胞移植到生物体组织等上的能够移动细胞的细胞转移基板，即使在细胞片的尺寸非常小的情况下， 细胞稀少培养; 细胞呈小菌落的形式; 或细胞以例如血管，血管网络例如淋巴管或神经网络的方式进行培养，并提供用于细胞转移基质的细胞转移用基板。 为了实现上述目的，本发明提供了一种用于电池转印的基板，包括：聚合物基材; 形成在聚合物基材上的中间层; 以及形成在中间层上的电池转印层。

公开(公告)号：US07156814B1

公开(公告)日：2007-01-02

申请号：US09890177

申请日：1998-10-05

申请人： Warren P. Williamson, IV ,  Stephen Whitlach ,  Dominic DiNovo ,  Douglas Allen ,  Thomas Ward

发明人： Warren P. Williamson, IV ,  Stephen Whitlach ,  Dominic DiNovo ,  Douglas Allen ,  Thomas Ward

IPC分类号： A61B10/00 ,  G01N1/30 ,  G01N33/48 ,  C12M1/12 ,  C12M1/22 ,  C12M3/00

CPC分类号： G01N1/36 ,  A61B10/0096 ,  G01N1/06 ,  G01N1/312 ,  G01N2001/315

摘要： A sectional cassette (10) for use in a process for harvesting and handling tissue samples for biopsy analysis is disclosed. In the procedure, a tissue biopsy sample is placed on a tissue trapping supporting material (A′) that can withstand tissue preparation procedures, and which can be cut with a microtome. The tissue is immobilized on the material, and the material and the tissue are held in the cassette (10) subjected to a process for replacing tissue fluids with wax. The tissue and supporting material are sliced for mounting on slides using a microtome. Harvesting devices and containers (200) using the filter material (202) are disclosed. An automated process is also disclosed.

摘要翻译： 公开了一种用于采集和处理组织样本用于活组织检查分析的方法的分段盒（10）。 在该过程中，将组织活检样品放置在可以承受组织制备程序的组织捕获支撑材料（A'）上，并且可以用切片机切割。 将组织固定在材料上，并将材料和组织保持在经过用蜡代替组织液的过程的盒（10）中。 使用切片机将组织和支撑材料切片以安装在载玻片上。 公开了使用过滤材料（202）的收获装置和容器（200）。 还公开了一种自动化过程。

公开(公告)号：US20060172412A1

公开(公告)日：2006-08-03

申请号：US11127898

申请日：2005-05-12

申请人： Eric Perrier ,  Odile Damour ,  Valerie Andre

发明人： Eric Perrier ,  Odile Damour ,  Valerie Andre

IPC分类号： C12M1/22 ,  C12M1/12

CPC分类号： C12M25/04 ,  C12M23/12 ,  C12M23/20 ,  C12M23/46 ,  C12M25/14 ,  C12M37/00 ,  C12M41/48

摘要： a cell culture device is disclosed having at least one cell-supporting layer of porous material obtained by dehydration of an aqueous gel which is poured directly either into said well bottom or into the bottom of a cradle or insert of a size which is adapted for being insertable into the volume of the well, thereby enabling by a robot or an automaton itself commanded by you computer.

摘要翻译： 公开了一种细胞培养装置，其具有通过将水凝胶脱水而获得的多孔材料的至少一个细胞支撑层，其直接倒入所述孔底或底座中，所述支架或插入物的尺寸适于 可插入井的体积，从而由机器人或自动机自身由电脑命令。

公开(公告)号：US20050282224A1

公开(公告)日：2005-12-22

申请号：US11197040

申请日：2005-08-04

申请人： Yves Fouillet ,  Claude Vauchier ,  Jean-Frederic Clerc ,  Christine Peponnet ,  Patricia Claustre ,  Raymond Charles ,  Nicolas Sarrut

发明人： Yves Fouillet ,  Claude Vauchier ,  Jean-Frederic Clerc ,  Christine Peponnet ,  Patricia Claustre ,  Raymond Charles ,  Nicolas Sarrut

IPC分类号： G01N33/50 ,  B01J19/00 ,  B01L3/00 ,  B01L7/00 ,  B01L7/02 ,  B81B1/00 ,  B81C1/00 ,  C12M1/00 ,  C12M1/22 ,  C12M1/34 ,  C12M1/38 ,  C12N15/09 ,  C12P19/34 ,  C12Q1/68 ,  G01N1/28 ,  G01N35/02 ,  G01N35/08 ,  G01N37/00

CPC分类号： G01N35/08 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/502707 ,  B01L3/502746 ,  B01L3/502784 ,  B01L7/02 ,  B01L7/52 ,  B01L7/525 ,  B01L7/5255 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2300/0845 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/1822 ,  B01L2300/1827 ,  B01L2300/1838 ,  B01L2300/1883 ,  B01L2400/0415 ,  B01L2400/0487 ,  F28F2260/02

摘要： Devices and methods for carrying out a chemical or biochemical protocol are disclosed. In one embodiment, the chemical or biochemical protocol is performed by cycling at least one thermal transfer member between at least two temperatures while liquid samples on which the chemical or biochemical protocol is to be performed are continuously moving through at least one temperature regulated zone upon which the at least one thermal transfer member acts. In some embodiments, the device comprises a sample transport member that comprises liquid samples in sample receiving regions. The sample transport member moves the samples continuously through a temperature regulated zone which cycles between at least two temperatures while the liquid samples are moving through a temperature regulated zone on which at least one thermal transfer member acts. In some embodiments, the sample receiving regions comprise wells, hydrophillic films or hydrophillic filaments.

摘要翻译： 公开了用于执行化学或生物化学方案的装置和方法。 在一个实施方案中，通过在至少两个温度之间循环至少一个热传递构件来执行化学或生物化学方案，而在其上执行化学或生物化学方案的液体样品连续移动通过至少一个温度调节区， 所述至少一个热转印构件起作用。 在一些实施例中，该装置包括样品输送构件，其在样品接收区域中包含液体样品。 样品输送构件将样品连续移动通过在至少两个温度之间循环的温度调节区，同时液体样品移动通过至少一个热转印构件作用的温度调节区。 在一些实施方案中，样品接收区域包括孔，亲水膜或亲水长丝。

公开(公告)号：US20050196857A1

公开(公告)日：2005-09-08

申请号：US11069009

申请日：2005-03-01

申请人： Yongjin Lee

发明人： Yongjin Lee

IPC分类号： G02B21/26 ,  C12M1/22

CPC分类号： G02B21/34 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/147 ,  B01L2300/041 ,  B01L2300/0654 ,  B01L2300/0822 ,  B01L2300/0877 ,  B01L2300/088 ,  B01L2300/18

摘要： Disclosed herein is a live cell chamber for a microscope. The live cell chamber comprises a chamber body, a transparent specimen plate, a specimen mounting base, and at least one sealing member. The chamber body includes at least one vertically perforated inner space, and a plurality of magnets. The specimen mounting base includes a specimen receiving portion, a magnetic member embedded around the specimen receiving portion such that the magnetic member can react to the magnets, and at least one through hole formed through the specimen receiving portion such that the center of the through hole is collinear with the center of the inner space of the chamber body. The sealing member is attached to the one end of the inner space while being attached at the other side to an upper surface of the specimen plate, thereby sealing a space defined between the inner space and the plate.

摘要翻译： 本文公开了用于显微镜的活细胞室。 活细胞室包括室主体，透明样品板，样品安装基座和至少一个密封构件。 室主体包括至少一个垂直穿孔的内部空间和多个磁体。 样本安装基座包括样本接收部分，磁性部件，其围绕检体接收部分嵌入，使得磁性部件能够对磁体作出反应;以及至少一个通孔，其穿过检测体接收部分形成，使得通孔的中心 与室体的内部空间的中心共线。 密封构件在另一侧附接到内部空间的一端附接到试样板的上表面，从而密封在内部空间和板之间限定的空间。

公开(公告)号：US06852525B1

公开(公告)日：2005-02-08

申请号：US10129248

申请日：2002-11-02

申请人： Hal C. Cantor

发明人： Hal C. Cantor

IPC分类号： C12M1/22 ,  C12M1/34

CPC分类号： C12M23/10 ,  B01L3/5085 ,  C12M23/20 ,  C12M41/46

摘要： The present invention relates to a cell culture chamber (10) having a sterile environment (12) for the culture of cells, a cover (14) for allowing for a transfer of pits and a sensor array.

摘要翻译： 本发明涉及具有用于培养细胞的无菌环境（12）的细胞培养室（10），用于允许传送凹坑和传感器阵列的盖（14）。

公开(公告)号：US5854065A

公开(公告)日：1998-12-29

申请号：US944173

申请日：1997-10-06

申请人： Dwight Livingston ,  Seibert Lowe ,  Frederic J. Marsik

发明人： Dwight Livingston ,  Seibert Lowe ,  Frederic J. Marsik

IPC分类号： C12M1/22 ,  C12M1/26 ,  C12M1/28 ,  C12M3/00

CPC分类号： C12M23/10 ,  G01N2001/028

摘要： A sampling device useful for determining whether microorganisms are present on a given surface includes a lid member and a base member. The lid member includes a flange that provides visual and tactile indications to a technician of the position of their fingers relative to an edge of the lid member. This increases the ability to avoid accidental or inadvertent contact with a sampling media. The flange is provided with a plurality of lugs that operate to maintain some spacing between the flange and a corresponding base member. This spacing is especially advantageous in situations where air flow is desirable within the sampling device. The base member includes a first cavity for supporting a sampling media and a second cavity. The second cavity includes a plurality of ribs that are contoured to securely fit a lid member partially within the second cavity so that a plurality of sampling devices can be stacked in a convenient and reliable fashion.

摘要翻译： 用于确定微生物是否存在于给定表面上的采样装置包括盖构件和基底构件。 盖构件包括法兰，其向技术人员提供其手指相对于盖构件的边缘的位置的视觉和触觉指示。 这增加了避免与采样介质意外或无意接触的能力。 凸缘设置有多个凸耳，其操作以在凸缘和相应的基部构件之间保持一些间隔。 在采样装置内需要气流的情况下，该间隔是特别有利的。 基座构件包括用于支撑采样介质和第二腔的第一腔。 第二腔包括多个肋，其轮廓是将盖构件部分地牢固地装配在第二腔内，使得可以以方便和可靠的方式堆叠多个采样装置。

公开(公告)号：US5817509A

公开(公告)日：1998-10-06

申请号：US818648

申请日：1997-03-19

申请人： Timothy A. Stevens ,  Tadeusz A. Tyndorf ,  Susan L. Barker

发明人： Timothy A. Stevens ,  Tadeusz A. Tyndorf ,  Susan L. Barker

IPC分类号： C12M1/22 ,  C12M1/20 ,  C12M3/00 ,  C12M3/06 ,  C12N5/06

CPC分类号： C12M25/04 ,  C12M23/12 ,  C12M23/24 ,  C12M23/38 ,  C12M29/04

摘要： A multiwell tissue culture assembly for culturing cells comprising a plate and a lid. The plate includes a plurality of wells for receiving liquids therein and the lid includes means for varying the gas diffusion into and out of the assembly and for substantially minimizing biological contamination of the cells being cultured. The means for varying the gas diffusion is a gas permeable membrane provided in an opening in the lid and a removable thin impermeable film label is provided for selectively occluding passage of gases through the gas permeable membrane. The means for minimizing biological contamination of the cells being cultured is a sealing material located in the lid and means for removably securing the lid and the plate together whereby the sealing material is compressed between the lid and the plate.

摘要翻译： 一种用于培养包含板和盖的细胞的多孔组织培养组件。 板包括用于在其中接收液体的多个孔，并且盖包括用于改变进入和离开组件的气体扩散并且用于基本上最小化被培养的细胞的生物污染的装置。 用于改变气体扩散的装置是设置在盖中的开口中的透气膜，并且提供可移除的薄不透水膜标签，用于选择性地封闭气体通过透气膜的通道。 用于最小化正在培养的细胞的生物污染的装置是位于盖中的密封材料和用于将盖和板可拆卸地固定在一起的装置，由此密封材料在盖和板之间被压缩。