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公开(公告)号：US20210354162A1
公开(公告)日：2021-11-18
申请号：US17227559
申请日：2021-04-12
发明人： Brendan HOGAN , Kieran HYLAND , Anthony REDMOND
摘要： An aerosol generator has a vibratable plate with apertures therein and an annular piezo which causes movement of the vibratable plate. An annular support member supports the piezo and the vibratable plate. A first electrical power conducting pin engages directly with a first, top, surface of the piezo. A second electrical power conducting pin indirectly conducts electrical power to a second surface of the piezo, by contacting an extension tab of the support member, also on its top side. There is a film of cured epoxy adhesive on the tab, providing excellent gripping force between the pin and the support. The aerosol generator avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the same lateral and top side of the piezo and support member. The pins may have multi-point tips for particularly effective electrical contact.
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公开(公告)号：US11027076B2
公开(公告)日：2021-06-08
申请号：US16019026
申请日：2018-06-26
发明人： Michael Casey , Joseph Grehan , Kieran Hyland , John Power
摘要： A nebulizer comprises a controller linked at its output to a nebulizer head, and at its input to a USB cable and USB plug for connection to a host system. The link between the USB plug and the controller is a USB cable with power and data channels. The controller comprises a boost circuit, a microcontroller 11, and a drive circuit. The latter provides power and control signals via a cable and proprietary plug to the nebulizer head. These signals provide power and control for a vibrating membrane receiving a liquid to be aerosolised. The controller has a housing with LED status lamps, and an ON/OFF button. The controller can be controlled via a host, either locally or remotely.
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公开(公告)号：US20200155786A1
公开(公告)日：2020-05-21
申请号：US16749024
申请日：2020-01-22
摘要： A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.
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公开(公告)号：US20200078536A1
公开(公告)日：2020-03-12
申请号：US16686286
申请日：2019-11-18
发明人： Brendan HOGAN
摘要： A photo-resist (21) is applied in a pattern or vertical columns having the dimensions of holes or pores of the aperture plate to be produced. This mask pattern provides the apertures which define the aerosol particle size, having up to 2500 holes per square mm. There is electro-deposition of metal (22) into the spaces around the columns (21). There is further application of a second photo-resist mask (25) of much larger (wider and taller) columns, encompassing the area of a number of first columns (21). The hole diameter in the second plating layer is chosen according to a desired flow rate.
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公开(公告)号：US10518288B2
公开(公告)日：2019-12-31
申请号：US15578923
申请日：2016-06-10
摘要： A method for aerosolising a liquid comprises the steps of: —providing an aperture plate having at least 100 outlet holes per mm2; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 to 15 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.
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公开(公告)号：US10508353B2
公开(公告)日：2019-12-17
申请号：US15625639
申请日：2017-06-16
发明人： Hong Xu
IPC分类号： C25D7/00 , B41J2/16 , C25D5/02 , C25D5/10 , C25D1/00 , B05B17/00 , C25D3/38 , C25D3/46 , C25D3/48 , C25D3/54 , C25D5/34 , C25D5/48 , C25D5/54
摘要： In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.
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公开(公告)号：US10449307B2
公开(公告)日：2019-10-22
申请号：US15933082
申请日：2018-03-22
发明人： Joseph Grehan , Niall Smith
IPC分类号： A61M11/00 , B05B17/06 , G01N29/22 , G01N29/42 , G06F19/00 , B05B17/00 , B06B1/02 , G16H20/13 , B05B15/14 , B05B12/00 , B05B12/08
摘要： A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号：US20190224709A1
公开(公告)日：2019-07-25
申请号：US16314830
申请日：2017-06-29
摘要： An aperture plate 1 comprises an inlet surface 2 for receiving a liquid to be aerosolised, an outlet surface 3 and a plurality of apertures 4 extending therebetween. The apertures 4 are tapered from an inlet opening 10 at the inlet surface 2 to an outlet or exit opening 12. The aperture plate 1 is convex in the direction of the inlet openings 10 and concave in the direction of the exit openings 12. The aerosol exits on the concave side of the aperture plate. The aperture plate of the invention generates an aerosol plume which converges and is particularly suitable for application to the eye.
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公开(公告)号：US20180214643A1
公开(公告)日：2018-08-02
申请号：US15933082
申请日：2018-03-22
发明人： Joseph Grehan , Niall SMITH
CPC分类号： A61M11/005 , A61M11/001 , A61M2205/33 , A61M2205/3317 , B05B12/004 , B05B12/081 , B05B15/14 , B05B17/0646 , B05B17/0669 , B06B1/0253 , G01N29/22 , G01N29/42 , G06F19/3456 , G16H20/13
摘要： A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
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公开(公告)号：US09981090B2
公开(公告)日：2018-05-29
申请号：US13902096
申请日：2013-05-24
发明人： Brendan Hogan
CPC分类号： A61M11/003 , A61M11/005 , B05B17/0646 , C25D1/08 , C25D3/567 , C25D7/00
摘要： A photo-resist is applied in a pattern of vertical columns having the dimensions of holes or pores of the aperture plate to be produced. This mask pattern provides the apertures which define the aerosol particle size, having up to 2500 holes per square mm. There is electro-deposition of metal into the spaces around the columns. There is further application of a second photo-resist mask of much larger (wider and taller) columns, encompassing the area of a number of first columns. The hole diameter in the second plating layer is chosen according to a desired flow rate.
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