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    Systems and related methods for optimization of multi-electrode nerve pacing
    64.
    发明授权
    Systems and related methods for optimization of multi-electrode nerve pacing 有权
    多电极神经起搏优化的系统及相关方法

    公开(公告)号：US09333363B2

    公开(公告)日：2016-05-10

    申请号：US14600763

    申请日：2015-01-20

    Applicant: Simon Fraser University

    Inventor： Joaquin Andres Hoffer ,  Gautam Sadarangani ,  Marc Andre Nolette ,  Viral Thakkar ,  Bao Dung Tran

    IPC: A61N1/36 ,  A61N1/05

    CPC classification number: A61N1/36185 ,  A61B5/0205 ,  A61B5/0245 ,  A61B5/04001 ,  A61B5/0422 ,  A61B5/0488 ,  A61B5/05 ,  A61B5/08 ,  A61B5/145 ,  A61B5/4818 ,  A61B5/4836 ,  A61B5/4893 ,  A61B5/6852 ,  A61B5/7264 ,  A61B2562/043 ,  A61N1/0551 ,  A61N1/3611 ,  A61N1/36139

    Abstract: This disclosure describes, among other embodiments, systems and related methods for selecting electrode combinations to be used during nerve pacing procedures. A first set of electrode combinations of a nerve pacing system, such as a phrenic nerve pacing system for diaphragm activation, may be mapped (or tested) to determine the location of the electrode combinations relative to a target nerve. Once the general location of the target nerve is known, a more localized second set of electrode combinations may be tested to determine the most suitable electrode combinations for nerve stimulation. At various stages of the mapping process, electrode combinations that are non-optimal may be discarded as candidates for use in a nerve pacing procedure. The systems and methods described herein may allow for the selection of electrode combinations that are most suitable for stimulation of the left and right phrenic nerves during diaphragm pacing.

    Abstract translation: 除了其它实施方式之外，本公开描述了用于选择在神经起搏过程中使用的电极组合的系统和相关方法。 可以映射（或测试）神经起搏系统的第一组电极组合，例如用于隔膜激活的膈神经起搏系统，以确定电极组合相对于目标神经的位置。 一旦目标神经的一般位置是已知的，可以测试更局限的第二组电极组合，以确定用于神经刺激的最合适的电极组合。 在映射过程的各个阶段，不优选的电极组合可被丢弃，作为在神经起搏过程中使用的候选。 本文描述的系统和方法可以允许选择最适合于在隔膜起搏期间刺激左膈神经和膈神经的电极组合。

    VECTOR LIGHT SENSOR AND ARRAY THEREOF
    65.
    发明申请
    VECTOR LIGHT SENSOR AND ARRAY THEREOF 审中-公开
    矢量光传​​感器及其阵列

    公开(公告)号：US20160123801A1

    公开(公告)日：2016-05-05

    申请号：US14952472

    申请日：2015-11-25

    Applicant: Simon Fraser University

    Inventor： Behraad Bahreyni

    IPC: G01J1/42 ,  H01L31/08 ,  H01L27/144 ,  H01L31/112 ,  H01L31/0352 ,  H01L37/02 ,  H01L31/09 ,  H01L31/102

    CPC classification number: H01L27/1446 ,  G01J1/0266 ,  G01J5/089 ,  G01S3/781 ,  G01S3/783 ,  G01S3/784 ,  H01L31/02024 ,  H01L37/02

    Abstract: A vector light sensor (VLS) includes a substrate and a sensor structure. The substrate includes a major surface. The sensor structure includes a pyramid structure, light-sensitive areas, and electrical contacts. The pyramid structure forms at least a portion of a body of the sensor structure and has predefined angles between the major surface of the substrate and a plurality of sidewalls of the pyramid. The light-sensitive areas are formed on two or more of the plurality of sidewalls of the pyramid structure. The electrical contacts are electrically coupled to the light-sensitive areas. Information about the information about intensity and direction of an incident light beam can be extracted by comparing signals from two or more of the light-sensitive areas.

    Abstract translation: 矢量光传​​感器（VLS）包括基板和传感器结构。 基板包括主表面。 传感器结构包括金字塔结构，感光区域和电触点。 金字塔结构形成传感器结构的主体的至少一部分，并且在基板的主表面和金字塔的多个侧壁之间具有预定的角度。 感光区域形成在金字塔结构的多个侧壁中的两个或多个上。 电触点电耦合到光敏区域。 可以通过比较来自两个或更多个感光区域的信号来提取关于入射光束的强度和方向的信息的信息。

    Transvascular nerve stimulation apparatus and methods
    67.
    发明授权
    Transvascular nerve stimulation apparatus and methods 有权
    经血管神经刺激装置及方法

    公开(公告)号：US09026231B2

    公开(公告)日：2015-05-05

    申请号：US14497858

    申请日：2014-09-26

    Applicant: Simon Fraser University

    Inventor： Joaquin Andres Hoffer

    IPC: A61N1/05 ,  A61N1/36

    CPC classification number: A61N1/3611 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/3601 ,  A61N1/36139 ,  A61N1/36185

    Abstract: Electrode structures for transvascular nerve stimulation combine electrodes with an electrically-insulating backing layer. The backing layer increases the electrical impedance of electrical paths through blood in a lumen of a blood vessel and consequently increases the flow of electrical current through surrounding tissues. The electrode structures may be applied to stimulate nerves such as the phrenic, vagus, trigeminal, obturator or other nerves.

    Abstract translation: 用于经血管神经刺激的电极结构将电极与电绝缘背衬层结合。 背衬层增加通过血管内腔中的血液的电路径的电阻抗，从而增加通过周围组织的电流的流动。 可以施加电极结构以刺激神经，例如膈神经，迷走神经，三叉神经，闭孔或其他神经。

    TRANSVASCULAR NERVE STIMULATION APPARATUS AND METHODS
    68.
    发明申请
    TRANSVASCULAR NERVE STIMULATION APPARATUS AND METHODS 审中-公开
    转移神经刺激装置及方法

    公开(公告)号：US20150045810A1

    公开(公告)日：2015-02-12

    申请号：US14383285

    申请日：2013-03-04

    Applicant: SIMON FRASER UNIVERSITY

    Inventor： Joaquin Andres Hoffer ,  Marc-Andre Nolette ,  Viral Thakkar ,  Bao Dung Tran

    IPC: A61N1/05

    Abstract: The invention, in one aspect, relates to an intravascular electrode system. The system comprises one or more electrodes supported on an elongated resiliently flexible support member, and the support member may be used to introduce the electrodes into a blood vessel. As the support member is introduced into the blood vessel the support member bends to follow the path of the blood vessel.

    Abstract translation: 本发明在一个方面涉及一种血管内电极系统。 该系统包括支撑在细长的弹性柔性支撑构件上的一个或多个电极，并且支撑构件可用于将电极引入血管。 当支撑构件被引入血管时，支撑构件弯曲以跟随血管的路径。

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