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公开(公告)号:US20210140979A1
公开(公告)日:2021-05-13
申请号:US17095178
申请日:2020-11-11
Applicant: AJOU UNIVERSITY INDUSTRY -ACADEMIC COOPERATION FOUNDATION , THE CATHOLIC UNIVERRSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Inventor: Suk JI , Young Kyung KO , Joo Cheol PARK , Man Bock GU , Seong Min BAK , Eun Mi LEE , Yea Jin LEE , Geum Bit HWANG , Bang Hyun LEE
Abstract: A method of diagnosing a periodontal condition using a protein showing a concentration difference between periodontal tissue in a normal condition and an abnormal condition from a subject's saliva is provided. According to this non-invasive method, the patient himself is able to check the presence of periodontal disease and identify the time to receive a treatment at an early stage, which will allow the patient to save time and cost for the treatment of periodontitis.
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62.
公开(公告)号:US10945637B2
公开(公告)日:2021-03-16
申请号:US15855504
申请日:2017-12-27
Inventor: Jin Hong Kim , Myung Hoon Sunwoo , Jung Won Lee
Abstract: Disclosed are image based jaundice analyzing method and apparatus. The image based jaundice analyzing method according to an exemplary embodiment of the present disclosure includes: receiving an image for jaundice diagnosis obtained by photographing a specific body part of a user and a reference object in a location where the user is currently located; generating color distortion information representing a degree of color distortion of the reference object included in the image for jaundice diagnosis; generating a correction image for jaundice diagnosis by correcting the color distortion of the image for jaundice diagnosis based on the color distortion information; and diagnosing a jaundice symptom of the user using the correction image for jaundice diagnosis.
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公开(公告)号:US10935423B2
公开(公告)日:2021-03-02
申请号:US16474378
申请日:2018-01-03
Inventor: Dong Woo Jee , Hyung Gi Kim
Abstract: A light-to-digital converter of the present invention includes: a plurality of light-to-digital conversion units each creating a first clock signal by performing delta-sigma conversion on a photodiode voltage created from an unbiased photodiode, and outputting a unit output signal obtained by synchronizing the first clock signal with a second clock signal that is a reference clock signal; and an adder outputting a digital output signal by adding up the unit output signals of the plurality of light-to-digital conversion units.
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64.
公开(公告)号:US10894895B2
公开(公告)日:2021-01-19
申请号:US15739628
申请日:2016-06-27
Inventor: Kyung Sook Kim , Da Yeon Kim , Seung Hun Park , Ja Yong Jang , Moon Suk Kim
IPC: C09D11/14 , C09D11/30 , C09D105/04 , C09D11/08 , C09D105/08 , C09D101/28 , C12N5/00 , A61K47/34 , A61K47/36 , A61K47/38 , A61L27/26 , A61L27/38 , A61L31/04 , A61L31/16 , C09D11/102
Abstract: The present invention provides a two-component bioink including a first solution and a second solution separately, wherein (i) the first solution includes a first biopolymer to which a first chemical functional group is introduced, and the second solution includes a second biopolymer to which a second chemical functional group able to chemically bond with the first chemical functional group is introduced; or (ii) the first solution includes a third biopolymer having a first electrostatic functional group, and the second solution includes a fourth biopolymer having a second electrostatic functional group able to physically bond with the first electrostatic functional group, a 3D biomaterial including the same, and a method for preparing the same.
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65.
公开(公告)号:US10888621B2
公开(公告)日:2021-01-12
申请号:US15475948
申请日:2017-03-31
Applicant: AJOU UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION , INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
Inventor: Ki Dong Park , Kyung Min Park , Yun Ki Lee , Thi Thai Thanh Hoang , Thi Phuong Le
Abstract: Provided are an injectable tissue adhesive hydrogel including gamma-cyclodextrin (γ-CD). When such an injectable tissue adhesive hydrogel including the γ-CD is used as a skin glue, based on a fact that the γ-CD has a bigger hydrophobic cavity than that of α- and β-CDs, the injectable tissue adhesive hydrogel including the γ-CD has stronger interactions than host-guest interactions. In addition, hydrogen bonding in the injectable tissue adhesive hydrogel including the γ-CD can improve both cohesiveness and adhesiveness of gelatin. The injectable tissue adhesive hydrogel including the γ-CD having excellent cell viability is used for adhesion of a skin incision, to thereby effectively promote tissue regeneration.
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公开(公告)号:US20210002546A1
公开(公告)日:2021-01-07
申请号:US15999776
申请日:2017-02-14
Inventor: Hyun C. YOON , Ka Ram KIM , Yong Duk HAN , Yoo Min PARK , Hyeong Jin CHUN
IPC: C09K11/06 , C09K11/77 , G01N33/533 , C01B33/18 , C09K11/02
Abstract: Disclosed is a method of manufacturing lanthanide fluorescent silica nanoparticles, including a complex synthesis step of synthesizing a silane-lanthanide chelate complex, an emulsion formation step of forming a water-in-oil microemulsion by dispersing micelles, the water-phase core of which is introduced with the silane-lanthanide chelate complex, in an oil-phase solvent, a silica introduction step of introducing a silica precursor into the microemulsion, and a nanoparticle synthesis step of synthesizing fluorescent silica nanoparticles by crosslinking the silica precursor and the silane-lanthanide chelate complex in the micelles. The lanthanide fluorescent silica nanoparticles thus manufactured can be utilized in fluorescence analysis of inorganic materials or bio-derived materials.
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公开(公告)号:US10857206B2
公开(公告)日:2020-12-08
申请号:US16174293
申请日:2018-10-30
Inventor: Hee Young Kang , Tae Jun Park , Jung Eun Yoon , Mi Sun Kim
Abstract: A method of preventing or treating cutaneous pigmentation disease in a subject in need thereof, includes: providing a pharmaceutical composition comprising SDF1, an inducer or activator of SDF1, as an active ingredient; and administering the pharmaceutical composition to the subject, wherein the cutaneous pigmentation is prevented or treated, and the cutaneous pigmentation disease is selected from the group consisting of melasma, freckles, lentigo, nevus, pigmentation by drugs, pigmentation after inflammation and hyperpigmentation incurred from dermatitis.
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公开(公告)号:US20200299330A1
公开(公告)日:2020-09-24
申请号:US16858071
申请日:2020-04-24
Inventor: Moon Suk KIM , Sang Dun CHOI , Seung Hun PARK , Masaud SHAH
Abstract: A substance P analog having a progenitor cell or stem cell recruiting activity and a method of recruiting progenitor cells or stem cells using the substance P analog are disclosed. The substance P analog has an effect of recruiting endogenous progenitor cells or stem cells to a wound or disease-occurring site. Thus, the disclosure also describes its use in recruiting progenitor cells or stem cells and a method of regenerating or treating a damaged organ or tissue, or a method of healing a wound.
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69.
公开(公告)号:US20200283725A1
公开(公告)日:2020-09-10
申请号:US16803957
申请日:2020-02-27
Inventor: Jong-Young KWAK , Minho CHOI , Gwang LEE
Abstract: A method of preparing a polyvinyl alcohol nanofiber membrane includes a material for controlling cell specific adhesion, and a nanofiber membrane that can maintain cellular functions such as cell activity and growth is prepared by adding aqueous solutions containing a polyacrylic acid and a glutaraldehyde crosslinking agent in a polyvinyl alcohol and materials capable of enhancing or regulating cell adhesion, electrospinning, treating with hydrochloric acid vapor and dimethylformaldehyde solvent and treating with sodium hydroxide to control the cell adhesion.
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公开(公告)号:US20200267215A1
公开(公告)日:2020-08-20
申请号:US16790938
申请日:2020-02-14
Inventor: Jai Hoon Kim , Kwang Hoon Choi , Dae Han Kim
Abstract: A node device on a blockchain network is provided. The node device includes a blockchain state monitor that calculates an estimated time of transaction processing completion according to a transaction cost by using state information about the blockchain network, a transaction cost determiner that calculates a minimum transaction cost that satisfies a user's requirements by using the calculated estimated time of transaction processing completion, and a transaction processor that processes a transaction of the user in response to a first transaction processing request when the first transaction processing request, which pays a transaction cost equal to or greater than the minimum transaction cost, is generated by the user.
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