公开(公告)号：US20210002546A1

公开(公告)日：2021-01-07

申请号：US15999776

申请日：2017-02-14

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Hyun C. YOON ,  Ka Ram KIM ,  Yong Duk HAN ,  Yoo Min PARK ,  Hyeong Jin CHUN

IPC: C09K11/06 ,  C09K11/77 ,  G01N33/533 ,  C01B33/18 ,  C09K11/02

Abstract: Disclosed is a method of manufacturing lanthanide fluorescent silica nanoparticles, including a complex synthesis step of synthesizing a silane-lanthanide chelate complex, an emulsion formation step of forming a water-in-oil microemulsion by dispersing micelles, the water-phase core of which is introduced with the silane-lanthanide chelate complex, in an oil-phase solvent, a silica introduction step of introducing a silica precursor into the microemulsion, and a nanoparticle synthesis step of synthesizing fluorescent silica nanoparticles by crosslinking the silica precursor and the silane-lanthanide chelate complex in the micelles. The lanthanide fluorescent silica nanoparticles thus manufactured can be utilized in fluorescence analysis of inorganic materials or bio-derived materials.

公开(公告)号：US20160109370A1

公开(公告)日：2016-04-21

申请号：US14645009

申请日：2015-03-11

Applicant: LG ELECTRONICS INC. ,  AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Yunhee KU ,  Moosub KIM ,  Yongju YANG ,  Seung Yeon SONG ,  Kang Sun LEE ,  Hyun Chul YOON ,  Yong Duk HAN ,  Yoo Min PARK

IPC: G01N21/76 ,  G03F7/20

CPC classification number: G03F7/2002 ,  G01N21/78 ,  G01N2400/00 ,  G03F7/027

Abstract: The present disclosure relates to a sensor for detecting saccharide and manufacturing method thereof and detection method of glycated hemoglobin using the same wherein the sensor for detecting saccharide includes a reactive layer synthesized with hydrogel having a boronic acid-modified 3D mesh structure. A selective and sensitive detection of the glycated protein including glucose or glycated hemoglobin (HbA1c) in blood through high level of signal may be enabled, and the durability of the sensor for detecting saccharide may be enhanced.

Abstract translation: 本发明涉及用于检测糖类的传感器及其制造方法以及使用该传感器的糖化血红蛋白的检测方法，其中用于检测糖的传感器包括与具有硼酸改性的3D网状结构的水凝胶合成的反应层。 可以通过高水平的信号选择性和灵敏地检测血液中的葡萄糖或糖化血红蛋白（HbA1c），并且可以增强用于检测糖的传感器的耐久性。