公开(公告)号：US20210002546A1

公开(公告)日：2021-01-07

申请号：US15999776

申请日：2017-02-14

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Hyun C. YOON ,  Ka Ram KIM ,  Yong Duk HAN ,  Yoo Min PARK ,  Hyeong Jin CHUN

IPC: C09K11/06 ,  C09K11/77 ,  G01N33/533 ,  C01B33/18 ,  C09K11/02

Abstract: Disclosed is a method of manufacturing lanthanide fluorescent silica nanoparticles, including a complex synthesis step of synthesizing a silane-lanthanide chelate complex, an emulsion formation step of forming a water-in-oil microemulsion by dispersing micelles, the water-phase core of which is introduced with the silane-lanthanide chelate complex, in an oil-phase solvent, a silica introduction step of introducing a silica precursor into the microemulsion, and a nanoparticle synthesis step of synthesizing fluorescent silica nanoparticles by crosslinking the silica precursor and the silane-lanthanide chelate complex in the micelles. The lanthanide fluorescent silica nanoparticles thus manufactured can be utilized in fluorescence analysis of inorganic materials or bio-derived materials.