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公开(公告)号：US20240066072A1
公开(公告)日：2024-02-29
申请号：US17764878
申请日：2020-09-28
发明人： Nobuhiko Kamada , Hiroko Kitamoto
CPC分类号： A61K35/74 , A61K38/20 , A61P31/04 , G01N33/6869 , A61K2035/115
摘要： Provided herein is technology relating to preventing and treating gastrointestinal dysbiosis and particularly, but not exclusively, to compositions, methods, systems, and kits for treating and/or preventing Clostridioides difficile infection in an organism.
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62.发明授权公开(公告)号：US11911128B2
公开(公告)日：2024-02-27
申请号：US17173976
申请日：2021-02-11
发明人： David T. Blaauw , Jamie Phillips , Cynthia Anne Chestek , Taekwang Jang , Hun-Seok Kim , Dennis Sylvester , Jongyup Lim , Eunseong Moon , Michael Barrow , Samuel Nason , Julianna Richie , Paras Patel
IPC分类号： A61B5/00 , H04B10/80 , H04B10/114 , A61B5/37 , A61B5/384
CPC分类号： A61B5/0017 , A61B5/0006 , A61B5/0031 , A61B5/37 , A61B5/384 , H04B10/114 , H04B10/80 , A61B2560/0219
摘要： A mote includes an optical receiver that wirelessly receives a power and data signal in form of NIR light energy within a patient and converts the NIR light energy to an electrical signal having a supply voltage. A control module supplies the supply voltage to power devices of the mote. A clock generation circuit locks onto a target clock frequency based on the power and data signal and generates clock signals. A data recovery circuit sets parameters of one of the devices based on the power and data signal and a first clock signal. An amplifier amplifies a neuron signal detected via an electrode inserted in tissue of the patient. A chip identifier module, based on a second clock signal, generates a recorded data signal based on a mote chip identifier and the neuron signal. A driver transmits the recorded data signal via a LED or a RF transmitter.
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公开(公告)号：US11903729B2
公开(公告)日：2024-02-20
申请号：US18128647
申请日：2023-03-30
发明人： Jerome P. Lynch , Wentao Wang
CPC分类号： A61B5/4851 , A61B5/4504 , A61B5/6811 , A61F2/76 , A61F2002/30784 , A61F2002/608 , A61F2002/7887 , A61F2310/00023
摘要： A method and an osseointegrated prosthesis system having an osseointegrated prosthesis member are provided having a monitoring system operably coupled to the osseointegrated prosthesis member configured to quantitatively assess the osseointegration of the osseointegrated prosthesis member, a wave-generating element coupled to the osseointegrated prosthesis member and configured to output guided waves along the osseointegrated prosthesis member interrogating an interface between bone and the osseointegrated prosthesis member, and a sensing system configured to sense a condition of the interface between bone and the prosthesis.
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公开(公告)号：US11901473B2
公开(公告)日：2024-02-13
申请号：US17232243
申请日：2021-04-16
发明人： Tobias Burger , Byungjun Lee , Dejiu Fan , Andrej Lenert , Stephen R. Forrest
IPC分类号： H01L31/0735 , H01L31/0687 , H01L31/18 , G03F7/00 , H01L31/0232 , H01L31/0264 , H01L33/00 , C30B25/04 , C30B25/22 , H01L31/043
CPC分类号： H01L31/0687 , C30B25/04 , C30B25/22 , G03F7/0005 , H01L31/0264 , H01L31/02327 , H01L31/043 , H01L31/0735 , H01L31/1852 , H01L31/1896 , H01L33/0093
摘要： To reach high efficiencies, thermophotovoltaic cells must utilize the broad spectrum of a radiative thermal source. One promising approach to overcome this challenge is to have low-energy photons reflected and reabsorbed by the thermal emitter, where their energy can have another chance at contributing toward photogeneration in the cell. However, current methods for photon recuperation are limited by insufficient bandwidth or parasitic absorption, resulting in large efficiency losses relative to theoretical limits. This work demonstrates nearly perfect reflection of low-energy photons (˜99%) by embedding an air layer within the TPV cell. This result represents a four-fold reduction in parasitic absorption relative to existing TPV cells. As out-of-band reflectance approaches unity, TPV efficiency becomes nearly insensitive to cell bandgap and emitter temperature. Accessing this regime unlocks a range of possible materials and heat sources that were previously inaccessible to TPV energy conversion.
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公开(公告)号：US11898132B2
公开(公告)日：2024-02-13
申请号：US17380833
申请日：2021-07-20
摘要： A bioreactor and method of forming complex three-dimensional tissue constructs in a single culture chamber. The bioreactor and methods may be used to form multi-phasic tissue constructs having tissue formed from multiple cell types in a single culture chamber. The bioreactor includes at least one translation mechanism to facilitate translation of one or more tissue constructs without direct user intervention, thereby providing a closed, sterile environment for complex tissue fabrication. The bioreactor may be used as a stand-alone device or as part of a large-scale system including many bioreactors. The large-scale system may include a perfusion system to monitor and regulate the tissue culture environment.
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公开(公告)号：US11895853B2
公开(公告)日：2024-02-06
申请号：US16722709
申请日：2019-12-20
发明人： Stephen Forrest , Quinn Burlingame , Caleb Coburn
CPC分类号： H10K30/82 , H10K85/215
摘要： Organic photovoltaic cells (OPVs) and their compositions are described herein. In one or more embodiments, the OPV or solar cell includes a first electrode (e.g., cathode); a second electrode (e.g., anode); an active layer positioned between the first electrode and the second electrode; and a channel layer positioned between the first electrode and the active layer, wherein the channel layer is configured to laterally disperse a charge across the channel layer. In certain examples, the first electrode is arranged in a grid structure having a plurality of electrode segments and a respective opening between adjacent segments of the first electrode.
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公开(公告)号：US11889709B2
公开(公告)日：2024-01-30
申请号：US15552303
申请日：2016-02-29
发明人： Stephen R. Forrest , Kyusang Lee
IPC分类号： H10K30/20 , H01L31/0687 , H01L31/0725 , H01L31/043 , H01L31/076 , H01L31/0232 , H01L31/078 , H10K30/57 , H10K30/87 , H10K85/20 , H01L31/054 , H01L31/101 , H01L31/0352
CPC分类号： H10K30/211 , H01L31/02327 , H01L31/035209 , H01L31/035218 , H01L31/043 , H01L31/0547 , H01L31/0687 , H01L31/076 , H01L31/078 , H01L31/0725 , H01L31/1013 , H10K30/57 , H10K30/87 , H10K85/215 , H10K85/211 , Y02E10/52 , Y02E10/544 , Y02E10/548 , Y02E10/549
摘要： A method of fabricating a multi-junction photosensitive device is provided. The method may include fabricating at least two photoactive layers, wherein at least one photoactive layer is fabricated on a transparent substrate, and at least one photoactive layer is fabricated on a reflective substrate, patterning at least one optical filter layer on at least one photoactive layer fabricated on a transparent substrate, and bonding the at least two photoactive layers using cold weld or van der Waals bonding. A multi-junction photosensitive device is also provided. The device may have at least two photoactive layers, and at least one optical filter layer, wherein at least two layers are bonded using cold weld or van der Waals bonding. The optical filter layer may be a Distributed Bragg Reflector.
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公开(公告)号：US20240024705A1
公开(公告)日：2024-01-25
申请号：US18478342
申请日：2023-09-29
申请人： The Regents of the University of Michigan , The United States Government as represented by the Department of Veterans Affairs
发明人： Zhen XU , Clifford Suhyun CHO
CPC分类号： A61N7/00 , A61K39/0011 , A61B10/0045
摘要： Systems and methods for histotripsy and immunotherapy are provided. In some embodiments, histotripsy can be applied to a target tissue volume to lyse and solubilize the target tissue volume to release tumor antigens. In some embodiments, an immune response of the treatment can be evaluated. In other embodiments, an immune therapy can be applied after applying the histotripsy. In one embodiment, the lysed and solubilized cells can be extracted from the tissue. The extracted cells can be used to create immune therapies, including vaccines.
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69.发明公开公开(公告)号：US20240019249A1
公开(公告)日：2024-01-18
申请号：US18209454
申请日：2023-06-13
发明人： Khalil NAJAFI , Sajal SINGH , Jae Yoong CHO
IPC分类号： G01C19/5783 , G01C19/00 , B81B3/00 , H03H3/007 , G01C19/5691 , H03H9/02 , G01C19/5684 , B81C1/00 , H03H9/24
CPC分类号： G01C19/5783 , G01C19/005 , B81B3/0021 , H03H3/0072 , G01C19/5691 , H03H9/02259 , G01C19/5684 , B81C1/00444 , H03H9/2405 , B81B2201/0242 , H03H2009/02496 , B81B2201/0271 , B81C2201/0143
摘要： Three-dimensional (3D) micro-scale shells are presented with selectively removed regions/openings and which can be used in sensors and actuators, including gyroscopes. Example shells consisting of a suspended ring-shaped resonator that is supported using multiple beams that are not in the plane of the ring and are attached to a support post can be formed. Shells with various sizes and geometries of selectively removed regions and openings allow the creation of micro electromechanical systems (MEMS) sensors and actuators with a wide range of engineered mechanical and electrical properties. These shells can be used to form stacked 3D structures for various types of MEMS sensor and actuator devices, such as resonant gyroscopes, with sense and drive electrodes that conform to the curved profile of the resonant shell using for gyroscopes. 3D shells formed from a starting parent substrate are released and separated from their parent substrate using a number of techniques.
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公开(公告)号：US11875708B2
公开(公告)日：2024-01-16
申请号：US16579959
申请日：2019-09-24
发明人： Kamal Sarabandi , Xiuzhang Cai
IPC分类号： G09B9/54 , G01S13/93 , G01S7/41 , G01S7/40 , G01S13/931
CPC分类号： G09B9/54 , G01S7/4052 , G01S7/415 , G01S13/931 , G01S7/4091
摘要： A real-time automotive radar simulation tool is developed based on reduced statistical models summarized from physical-based asymptotic and full-wave simulations. Some models have been verified with measurements. The simulation tool can help save cost and time for the automotive industry, especially for autonomous vehicles. The simulation tool can also help develop new functionalities like target identification or classification as well as help prevent false alarms.
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