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公开(公告)号:US20170210807A1
公开(公告)日:2017-07-27
申请号:US15485159
申请日:2017-04-11
Applicant: Genentech, Inc.
Inventor: Sherman Fong , Mark Dennis
IPC: C07K16/28
CPC classification number: C07K16/2839 , A61K2039/505 , C07K16/18 , C07K16/2827 , C07K2317/14 , C07K2317/24 , C07K2317/41 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides therapeutic anti-beta7 antibodies, compositions comprising, and methods of using these antibodies.
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公开(公告)号:US20170174782A1
公开(公告)日:2017-06-22
申请号:US15296454
申请日:2016-10-18
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/32 , C07K16/30 , A61K31/675 , A61K31/704 , A61K31/5517 , G01N33/574 , A61K49/00
CPC classification number: C07K16/32 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K39/3955 , A61K47/68 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K47/6863 , A61K49/00 , C07K16/2863 , C07K16/3015 , C07K2317/24 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92 , G01N33/57415 , G01N33/57446 , G01N33/57492 , G01N2333/82
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
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53.COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR 审中-公开
Title translation: 用于诊断和治疗肿瘤的组合物和方法公开(公告)号:US20170073424A1
公开(公告)日:2017-03-16
申请号:US15341261
申请日:2016-11-02
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Bonnee Rubinfeld , Paul Polakis
IPC: C07K16/30 , A61K47/48 , A61K31/537 , G01N33/574
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US20160096893A1
公开(公告)日:2016-04-07
申请号:US14851001
申请日:2015-09-11
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Jagath Reddy Junutula , Gail Lewis Phillips , Thomas Harden Pillow , Mark X. Sliwkowski
IPC: C07K16/28 , A61K39/395 , G01N33/574 , A61K47/48
CPC classification number: C07K16/32 , A61K31/5517 , A61K31/675 , A61K31/704 , A61K39/3955 , A61K47/68 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K47/6863 , A61K49/00 , C07K16/2863 , C07K16/3015 , C07K2317/24 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92 , G01N33/57415 , G01N33/57446 , G01N33/57492 , G01N2333/82
Abstract: The invention provides anti-HER2 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗HER2抗体和免疫缀合物及其使用方法。
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公开(公告)号:US09029511B2
公开(公告)日:2015-05-12
申请号:US13963269
申请日:2013-08-09
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Bonnee Rubinfeld , Paul Polakis
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20140314794A1
公开(公告)日:2014-10-23
申请号:US14108820
申请日:2013-12-17
Applicant: Genentech, Inc.
Inventor: Mark Dennis , William Mallet , Paul Polakis
IPC: A61K47/48 , A61K38/08 , A61K45/06 , A61K31/4025
CPC classification number: A61K47/6803 , A61K31/337 , A61K31/4025 , A61K31/4196 , A61K31/513 , A61K31/517 , A61K31/519 , A61K31/537 , A61K31/555 , A61K31/7068 , A61K31/7072 , A61K38/07 , A61K38/08 , A61K45/06 , A61K47/6817 , A61K47/6835 , A61K47/6851 , A61K2039/505 , C07K16/3015 , C07K16/303 , C07K16/3069 , C07K16/3092 , C07K2317/24 , C07K2317/55 , C07K2317/565 , Y10T428/13
Abstract: The invention is directed to antibody drug conjugate compositions of matter useful for the diagnosis and treatment of tumors in mammals and to methods of using those compositions of matter for the same.
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57.COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR 审中-公开
Title translation: 用于诊断和治疗肿瘤的组合物和方法公开(公告)号:US20140079721A1
公开(公告)日:2014-03-20
申请号:US13963269
申请日:2013-08-09
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Bonnee Rubinfeld , Paul Polakis
CPC classification number: C07K16/30 , A61K31/537 , A61K45/06 , A61K47/6803 , A61K47/6809 , A61K47/6813 , A61K47/6817 , A61K47/6849 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K2039/505 , C07K16/18 , C07K16/28 , C07K16/3023 , C07K16/3069 , C07K2317/14 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/57423 , G01N33/57449 , G01N33/57492
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US20140050744A1
公开(公告)日:2014-02-20
申请号:US13945052
申请日:2013-07-18
Applicant: Genentech, Inc.
Inventor: Mark Dennis , William Mallet , Paul Polakis
IPC: A61K47/48
CPC classification number: A61K47/6803 , A61K31/337 , A61K31/4025 , A61K31/4196 , A61K31/513 , A61K31/517 , A61K31/519 , A61K31/537 , A61K31/555 , A61K31/7068 , A61K31/7072 , A61K38/07 , A61K38/08 , A61K45/06 , A61K47/6817 , A61K47/6835 , A61K47/6851 , A61K2039/505 , C07K16/3015 , C07K16/303 , C07K16/3069 , C07K16/3092 , C07K2317/24 , C07K2317/55 , C07K2317/565 , Y10T428/13
Abstract: The invention is directed to antibody drug conjugate compositions of matter useful for the diagnosis and treatment of tumors in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20130157289A1
公开(公告)日:2013-06-20
申请号:US13692888
申请日:2012-12-03
Applicant: Genentech, Inc.
Inventor: Mark Dennis , Jan Marik , Paul Polakis , Bonnee Rubinfeld , Simon Williams
CPC classification number: C07K16/40 , A61K47/6811 , A61K47/6871 , A61K51/1072 , A61K51/1075 , A61K51/1093 , A61K51/1096 , A61K2039/505 , C07B59/008 , C07B2200/05 , C07K16/3069 , C07K2317/24 , C07K2317/565 , C07K2317/92 , G01N33/534 , G01N33/57492 , G01N33/60 , G01N33/6893
Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of detecting or determining the presence of STEAP-1 proteins are provided.
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