公开(公告)号：US20220168475A1

公开(公告)日：2022-06-02

申请号：US17675343

申请日：2022-02-18

Applicant: TERUMO KABUSHIKI KAISHA

Inventor： Yuki UENO ,  Masanori KURAMOTO ,  Hiroki HOSONO ,  Hiromasa KOHAMA

IPC: A61L29/08 ,  A61L29/14 ,  A61L31/10 ,  A61L31/14

Abstract: A medical device that exhibits an excellent lubricating property includes: a substrate layer; and a surface lubricious layer formed on at least a part of the substrate layer, and containing a hydroxy group-containing compound selected from a group consisting of a non-volatile alcohol, a partially esterified product thereof, and a partially etherified product thereof, and soluble in water, and a hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from a group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group.

公开(公告)号：US20220133514A1

公开(公告)日：2022-05-05

申请号：US17088102

申请日：2020-11-03

Applicant: BRIAN THORSON

Inventor： BRIAN THORSON ,  KELLIE R. BROWN ,  BENJAMIN HEARD

IPC: A61F2/962 ,  A61F2/07 ,  A61L29/02 ,  A61L29/14

Abstract: A device for extracting an endovascular stent graft from a vessel including a cylindrical body and an opening formed in the cylindrical body. The cylindrical body has a first open end, a second open end, and a sidewall surrounding a hollow bore of the cylindrical body. The opening is formed in the sidewall between the first open end and the second open end forming a first ring portion at the first open end and a second ring portion at the second open end. Additionally, a thickness of the sidewall at the first open end tapers toward the opening and wherein a thickness of the sidewall at the second open end tapers toward the opening such that the hollow bore is narrower at each end than at the opening.

公开(公告)号：US20220117230A1

公开(公告)日：2022-04-21

申请号：US17457186

申请日：2021-12-01

Applicant: Nevada Naturals Inc.

Inventor： Anthony J. Sawyer ,  Richard F. Stockel

IPC: A01N47/44 ,  A01N43/16 ,  A01N37/36 ,  A61L31/14 ,  A61L27/52 ,  A61L29/16 ,  A61L15/20 ,  A61L31/10 ,  A61L31/16 ,  A61L29/08 ,  A61L17/00 ,  A61L29/14 ,  A61L27/54 ,  A61L15/60 ,  A61L27/34 ,  A61L15/46

Abstract: Compositions are provided that have at least two of three active ingredients. The active ingredients maybe a salt having a cation NαC8-C16 alkanoyl-L di-basic amino acid —C1-C4 alkyl ester, a glycerol monoester of a fatty acid and a sugar ester of a fatty acid. The compositions are useful in methods of killing or inhibiting planktonic bacteria or fungi and bacteria or fungi embedded in a biofilm and prevention of biofilm formation on surfaces. The composition may further comprise a hydrogel and a benefit agent such as an antibiotic that can be solubilized by the hydrogel and supplied to the biofilm matrix by the active ingredients of the composition. Devices such as chronic wound coverings coated with the composition are also provided. Methods of preserving products with the composition are also provided.

公开(公告)号：US20220112657A1

公开(公告)日：2022-04-14

申请号：US17559576

申请日：2021-12-22

Applicant: Hitachi Metals, Ltd.

Inventor： Seiichi KASHIMURA ,  Masamichi KISHI ,  Takanobu WATANABE ,  Kimika KUDO ,  Masashi ARAI

IPC: D07B5/00 ,  A61L29/04 ,  A61L29/08 ,  A61L29/12 ,  A61L29/14 ,  D07B1/16 ,  A61M25/00

Abstract: A cable includes a sheath, and a coating film covering a circumference of the sheath. The coating film adheres to the sheath. The static friction coefficient of a surface of the coating film is smaller than the static friction coefficient of a surface of the sheath. The adhesion strength between the sheath and the coating film is 0.30 MPa or more.

公开(公告)号：US11291749B2

公开(公告)日：2022-04-05

申请号：US17009473

申请日：2020-09-01

Applicant: Becton, Dickinson and Company

Inventor： Bryan Fred Bihlmaier ,  Weston F. Harding ,  Janice Lin ,  Huibin Liu ,  Siddarth K. Shevgoor ,  Jonathan Karl Burkholz ,  Yiping Ma ,  Ming Zhou

IPC: A61L29/16 ,  A61L29/12 ,  A61M31/00 ,  A61L29/14 ,  A61L29/06

Abstract: Inserts can be formed with elution characteristics to cause the inserts to elute an antimicrobial agent when subject to a fluid within a medical device. An insert can be formed with a desired geometry to allow the insert to be compression fit within a medical device to prevent the insert from moving or becoming dislodged once inserted into the medical device. The material may also be hygroscopic so that the insert swells when subject to a fluid thereby enhancing the compression fit of the device within the medical device. In some cases, the material can be reinforced using an internal structure. Inserts can be formed in many ways including by casting, thermoforming, or extrusion. In some cases, the inserts can be formed using a peel-away sleeve or material. The peel-away sleeves can be formed of a non-sticky material which facilitates removal of the inserts once the inserts have cured.

公开(公告)号：US20220099223A1

公开(公告)日：2022-03-31

申请号：US17033511

申请日：2020-09-25

Applicant: CareFusion 303, Inc.

Inventor： Fanqing Meng ,  Marc William Weimer

IPC: F16L11/12 ,  B29C48/09 ,  B29C48/21 ,  A61M25/00 ,  A61M25/01 ,  A61M5/14 ,  A61L29/04 ,  A61L29/14

Abstract: Tubing, such as medical tubing for administration of intravenous fluid, can include an inner layer, an outer layer concentrically disposed about and surrounding the inner layer, and an intermediate layer interposed between the inner and outer layers. The intermediate layer may include a light protection additive therein.

公开(公告)号：US11286615B2

公开(公告)日：2022-03-29

申请号：US16411709

申请日：2019-05-14

Applicant: Hitachi Metals, Ltd.

Inventor： Seiichi Kashimura ,  Masamichi Kishi ,  Takanobu Watanabe ,  Kimika Kudo ,  Masashi Arai

IPC: D07B5/00 ,  A61L29/04 ,  A61L29/08 ,  A61L29/12 ,  A61L29/14 ,  D07B1/16 ,  A61M25/00

Abstract: A cable includes a sheath, and a coating film covering a circumference of the sheath. The coating film adheres to the sheath. The static friction coefficient of a surface of the coating film is smaller than the static friction coefficient of a surface of the sheath. The adhesion strength between the sheath and the coating film is 0.30 MPa or more.

公开(公告)号：US11266768B2

公开(公告)日：2022-03-08

申请号：US15039136

申请日：2014-11-26

Applicant: TRUSTEES OF BOSTON UNIVERSITY

Inventor： Mark Grinstaff ,  Jonah Andrew Kaplan ,  Julia Wang

IPC: A61K9/26 ,  A61L31/14 ,  A61L27/34 ,  A61L27/50 ,  A61L27/54 ,  A61L29/08 ,  A61L29/14 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61K9/51 ,  A61K9/50

Abstract: The disclosure provides a drug delivery device that can release a drug or other molecule of interest in response to application of a mechanical force, such as tension, and methods of use thereof. The present disclosure provides a tension-responsive drug delivery device by exploiting a difference in mechanical properties between a drug-loaded core material and a supertiydrophobic barrier coating consisting of interconnected micro- and nano-sized particles formulated via the electrospraying of a mixture of biocompatible polymers.

公开(公告)号：US11260150B2

公开(公告)日：2022-03-01

申请号：US16726750

申请日：2019-12-24

Applicant: Tangible Science, Inc.

Inventor： Karen Havenstrite ,  Victor W. McCray ,  Brandon M. Felkins ,  Paul Cook

IPC: A61L29/14 ,  A61L27/52 ,  A61L27/54 ,  A61L29/08 ,  A61L29/16 ,  A61L31/10 ,  A61L31/14 ,  A61L15/60 ,  A61L27/34 ,  A61L31/16 ,  A61L15/46

Abstract: Medical devices with a hydrogel layer covalently attached to a portion of the outer surface of the medical device are provided along with methods for applying the coating. The hydrogel layer can include a first polymer species comprising polyethylene glycol (PEG) and a second polymer species. Examples of the second polymer species include PEG and polyacrylamide (PAM). The first and second species can be at least partially cross-linked. Methods for forming the hydrogel coatings on the medical devices are provided including nucleophilic conjugate reactions, such as Click reactions.

公开(公告)号：US20220054801A1

公开(公告)日：2022-02-24

申请号：US17453801

申请日：2021-11-05

Applicant: MicroVention, Inc.

Inventor： Ross Tsukashima ,  Heath Bowman

IPC: A61M25/01 ,  A61M25/04 ,  A61B17/12 ,  A61B17/22 ,  A61M13/00 ,  A61M16/04 ,  A61M11/00 ,  A61M25/00 ,  A61L29/14

Abstract: Implants comprising electrically-responsive hydrogel are described. Systems to provide electricity to induce response in hydrogel-containing implants are described. Methods for utilizing said system and methods for utilizing said hydrogel-containing implants are described.