公开(公告)号：US07094205B2

公开(公告)日：2006-08-22

申请号：US10117763

申请日：2002-04-05

申请人： Vasilis Z. Marmarelis

发明人： Vasilis Z. Marmarelis

IPC分类号： A61B8/02

CPC分类号： A61B8/0825 ,  A61B8/406 ,  A61B8/483 ,  A61B90/17

摘要： A system for providing high resolution imaging of objects having sub-millimeter dimensions comprised of at least one transmitter, at least one receiver, a coupling chamber, and a processor for recording attenuation and time of flight profiles of the transmitted signals. The signals are conditioned in a manner to provide high signal-to-noise ration (SNR) and minimal crosstalk and multipath effects at the receiver.

摘要翻译： 一种用于提供具有亚毫米尺寸的物体的高分辨率成像的系统，其包括至少一个发射器，至少一个接收器，耦合室和用于记录发射信号的衰减和飞行时间的处理器。 这些信号的调理方式是在接收机上提供高信噪比（SNR）和最小的串扰和多路径效应。

公开(公告)号：US06786868B2

公开(公告)日：2004-09-07

申请号：US10393826

申请日：2003-03-21

申请人： Rainer Stotzka ,  Werner A. Kaiser ,  Hartmut Gemmeke

发明人： Rainer Stotzka ,  Werner A. Kaiser ,  Hartmut Gemmeke

IPC分类号： A61B800

CPC分类号： A61B8/0825 ,  A61B8/14 ,  A61B8/406

摘要： In a high resolution ultrasonic tomograph operating according to transmission, scattering and impulse-echo methods, comprising a container with an open top and including ultrasonic transducers arranged along the walls of the container, a coupling medium disposed in the container and a computer-based control and evaluation unit with a working memory, the control and evaluation unit is connected in a circuit with the ultrasonic transducers in such a way that the ultrasonic signal emitted from at least one ultrasonic transducer forms an ultrasonic impulse which is received by all the other transducers in parallel and is amplified, filtered and digitized to form electric signals which are stored in the working memory as a data set.

摘要翻译： 在根据透射，散射和脉冲回波方法操作的高分辨率超声波断层摄影机中，包括具有敞开顶部并且包括沿容器壁布置的超声换能器的容器，设置在容器中的耦合介质和基于计算机的控制 以及具有工作存储器的评估单元，所述控制和评估单元以与所述超声换能器的电路连接的方式使得从至少一个超声波换能器发射的超声波信号形成超声波脉冲，所述超声波脉冲由所有其它换能器接收 并行放大，滤波和数字化，形成作为数据组存储在工作存储器中的电信号。

公开(公告)号：US20040030227A1

公开(公告)日：2004-02-12

申请号：US10440427

申请日：2003-05-16

申请人： Barbara Ann Karmanos Cancer Institute

发明人： Peter J. Littrup ,  Nebojsa Duric ,  Earle Holsapple III

IPC分类号： A61B005/00

CPC分类号： A61N7/02 ,  A61B8/0825 ,  A61B8/40 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4483 ,  A61B8/483 ,  A61B8/5223

摘要： A method for treating a medical pathology includes receiving a first set of acoustic radiation scattered by a volume of tissue containing at least a portion of the medical pathology and thereafter, changing a temperature of the volume of tissue. The method also includes thereafter, receiving a second set of acoustic radiation scattered by the volume of tissue and localizing the portion of the medical pathology from the first and second sets of received acoustic radiation. Localizing the portion of the medical pathology comprises identifying the medical pathology from differences in the first and second sets of received acoustic radiation resulting from the change in temperature. The method also includes insonifying the portion of the medical pathology with sufficient energy to damage the portion of the medical pathology.

摘要翻译： 用于治疗医学病理学的方法包括接收由包含至少一部分医学病理学的体积的组织散射的第一组声辐射，然后改变组织体积的温度。 该方法还包括此后，接收由该组织体积散射的第二组声辐射，并将该部分医学病理学从第一和第二组接收的声辐射定位。 定位医学病理学的一部分包括从温度变化引起的第一组和第二组接收的声辐射中的差异识别医学病理学。 该方法还包括用足够的能量来使医学病理学的部分松弛以损坏医学病理学的一部分。

公开(公告)号：US06636584B2

公开(公告)日：2003-10-21

申请号：US10024035

申请日：2001-12-17

申请人： Steven A. Johnson ,  David T. Borup ,  James Wiskin ,  Michael J. Berggren

发明人： Steven A. Johnson ,  David T. Borup ,  James Wiskin ,  Michael J. Berggren

IPC分类号： G01N2300

CPC分类号： G06T11/006 ,  A61B5/05 ,  A61B5/0507 ,  A61B5/4312 ,  A61B5/7257 ,  A61B8/0825 ,  A61B8/14 ,  A61B8/15 ,  A61B8/406 ,  A61B8/4209 ,  A61B8/4483 ,  A61B8/485 ,  G01H3/125 ,  G01N22/00 ,  G01N23/2055 ,  G01S13/103 ,  G01S13/89 ,  G01S15/04 ,  G01S15/88 ,  G01S15/89 ,  G01S15/8909 ,  G01S15/8913 ,  G01S15/8929 ,  G01S15/8938 ,  G01S15/895 ,  G01S15/8977 ,  G01S15/96 ,  G01V1/003 ,  G06T2211/408 ,  G06T2211/424 ,  Y10S378/901

摘要： A method for increasing the speed of the parabolic marching method by about a factor of 256. This increase in speed can be used to accomplish a number of important objectives. Firstly, the speed can be used to collect data to form true 3-D images or 3-D assembled from 2-D slices. Speed allows larger images to be made. Secondly, the frequency of operation can be increased to 5 MHz to match the operating frequency of reflection tomography. This allow the improved imaging of speed of sound which in turn is used to correct errors in focusing delays in reflection tomography imaging. This allows reflection tomography to reach or closely approach its theoretical spatial resolution of ½ to ¾ wave lengths. A third benefit of increasing the operating frequency of inverse scattering to 5 MHz is the improved out of topographic plane spatial resolution. This improves the ability to detect small lesions. It also allow the use of small transducers and narrower beams so that slices can be made closer to the chest wall.

摘要翻译： 一种用于将抛物线行进方法的速度提高约256倍的方法。这种速度的提高可以用于实现一些重要的目标。 首先，速度可以用于收集数据，以形成真正的3-D图像或从2D切片组装的3-D图像。 速度允许制作更大的图像。 其次，操作频率可以提高到5 MHz以匹配反射层析成像的工作频率。 这允许对速度的改进的成像，其进而用于校正反射层析成像中的聚焦延迟中的误差。 这允许反射层析成像达到或接近其理论空间分辨率为1/2至¾波长。 将反向散射的工作频率增加到5MHz的第三个好处是从地形平面空间分辨率得到改善。 这提高了检测小病变的能力。 它还允许使用小的换能器和较窄的梁，使得切片可以靠近胸壁。

公开(公告)号：US20030073895A1

公开(公告)日：2003-04-17

申请号：US10260719

申请日：2002-09-27

发明人： Morgan W. Nields ,  John Connor ,  Curtis Daly

IPC分类号： A61B005/05

CPC分类号： A61B6/502 ,  A61B6/0435 ,  A61B6/4417 ,  A61B6/463 ,  A61B6/465 ,  A61B6/469 ,  A61B6/5247 ,  A61B8/0825 ,  A61B8/406 ,  A61B8/4416 ,  A61B8/463 ,  A61B8/464 ,  A61B8/465 ,  A61B8/467 ,  A61B8/469 ,  A61B8/5238 ,  Y10S128/915 ,  Y10S128/916

摘要： The present invention provides for x-ray imaging and ultrasound imaging of a body region of interest in a spatially correlatable manner. The resultant x-ray and ultrasound images may be combinatively employed to provide three-dimensional information regarding a location of interest within the body, and is particularly apt for use in the analysis/biopsy of potential lesions and suspicious masses in a female breast. The invention provides for direct body contact by an ultrasound imaging head, as well as targeted ultrasound imaging of a selected portion of the region from which xray images are obtained. A user interface system facilitates various procedures including ultrasound guided needle biopsy procedures.

摘要翻译： 本发明以空间可相关的方式提供感兴趣的身体区域的X射线成像和超声成像。 可以组合使用所得的X射线和超声图像以提供关于身体内的感兴趣位置的三维信息，并且特别适合用于女性乳房中潜在损伤和可疑肿块的分析/活检。 本发明提供了通过超声成像头的直接身体接触以及从其获得X射线图像的区域的选定部分的目标超声成像。 用户界面系统促进包括超声引导针活检程序在内的各种程序。

公开(公告)号：US06524246B1

公开(公告)日：2003-02-25

申请号：US09687128

申请日：2000-10-13

申请人： Kevin M. Kelly ,  Roger Royce ,  Richard J. Peterson ,  Christopher Mark Underbrink ,  Luis E. Ponce ,  Matthew Warren Smith ,  Donald C. Goss

发明人： Kevin M. Kelly ,  Roger Royce ,  Richard J. Peterson ,  Christopher Mark Underbrink ,  Luis E. Ponce ,  Matthew Warren Smith ,  Donald C. Goss

IPC分类号： A61B800

CPC分类号： A61B8/0825 ,  A61B8/085 ,  A61B8/145 ,  A61B8/406 ,  A61B8/4209 ,  A61B8/4218 ,  A61B8/4245 ,  A61B8/4254 ,  A61B8/4281 ,  A61B8/4444 ,  A61B8/463 ,  A61B8/488 ,  A61B8/5223 ,  A61B8/54 ,  A61B8/565 ,  B82Y15/00

摘要： Ultrasonic scanning and diagnostics for cellular tissue are disclosed. An ultrasonic probe is moved across cellular tissue at a rate that is synchronized with the image capture rate of the ultrasonic scanner, to achieve a contiguous and complete set of scan images, of the tissue. The probe can be held in a single position as it is moved across the tissue, or it can be dynamically adjusted during the scan to provide optimal contact with the scanned tissue. The image data are captured and converted to a format that is easily stored and compatible with a viewer. The viewer allows playback of the scanned images in a manner that is optimized for screening for cancers and other anomalies. A location function allows the user to select a point of interest on an individual scan image, and choose another known reference point, and the function calculates and provides the distance from the reference point to the point of interest in three dimensions. The system can be used for virtually any tissue, but can also be optimized for breast cancer screening. A pad of different density may be placed over the nipple to provide a reference point that is visible in the scan images. The breast may be covered with a fabric that is constructed in such a manner to hold the breast in place and reduce ultrasonic scanning errors, as well as holding the pad in place. The location function described above will use the nipple pad as a reference point from which to measure any detected cancers or other anomalies.

摘要翻译： 公开了用于细胞组织的超声波扫描和诊断。 超声波探头以与超声波扫描器的图像捕获速率同步的速率移动穿过细胞组织，以实现组织的连续且完整的扫描图像组。 探针可以在移动穿过组织时保持在单个位置，或者可以在扫描期间动态地调整探针以提供与扫描的组织的最佳接触。 拍摄图像数据并将其转换为容易存储并与观看者兼容的格式。 观看者允许以针对癌症和其他异常的筛选进行优化的方式回放扫描的图像。 位置功能允许用户在单独的扫描图像上选择兴趣点，并选择另一个已知的参考点，并且该函数计算并提供三维中从参考点到感兴趣点的距离。系统可以 用于几乎任何组织，但也可以优化乳腺癌筛查。 可以将不同密度的垫放置在乳头上以提供在扫描图像中可见的参考点。 乳房可以用织物覆盖，该织物以这样的方式构造，以将乳房保持在适当位置并减少超声扫描误差，以及将垫保持在适当位置。 上述位置功能将使用乳头垫作为参考点，从中测量任何检测到的癌症或其他异常。

公开(公告)号：US5833633A

公开(公告)日：1998-11-10

申请号：US963385

申请日：1997-11-03

申请人： Armen Paruir Sarvazyan

发明人： Armen Paruir Sarvazyan

IPC分类号： A61B5/00 ,  A61B1/005 ,  A61B5/03 ,  A61B5/103 ,  A61B8/08 ,  A61B10/00 ,  A61B8/12

CPC分类号： A61B5/4312 ,  A61B1/0052 ,  A61B5/0053 ,  A61B5/036 ,  A61B5/064 ,  A61B8/0825 ,  A61B8/0833 ,  A61B8/406 ,  A61B8/485 ,  G01S7/52042 ,  A61B2562/0247 ,  A61B2562/046

摘要： In one embodiment of the invention, a pressure sensor array, data acquisition circuit, and a microprocessor are mounted in a hand held pad. Detection of nodules is achieved by analyzing the dynamic and spatial features of the pressure pattern while the probe pressed to the breast is periodically moved transversely to the ribs. The ribs play a role as an amplifier of the measured effect. The device will be able to objectively detect the presence of lumps in a breast and provide a warning signal. Another embodiment of the invention is a clinical device for imaging the mechanical structure of the examined breast and diagnosing diseases accompanied by changes in the elasticity of breast tissue. This embodiment is made up of an electronically controlled mechanical scanning unit incorporated into a patient support bed. The mechanical scanning unit includes a compression mechanism and positioning system, a local pressure source located opposite a pressure sensor array, and electronic control and interface circuitry. The local pressure source is either a roller moving over the examined breast, or in another embodiment, an indenter which can be moved in all three dimensions and be controlled either automatically by a computer or manually by a mouse. In yet another embodiment, the mechanical scanning system serves as a biopsy guidance means and determines target lesions in the breast to be reached by a biopsy gun or aspiration needle.

摘要翻译： 在本发明的一个实施例中，压力传感器阵列，数据采集电路和微处理器安装在手持垫中。 通过分析压力图形的动态和空间特征，同时按压到乳房的探针周期性地横向移动到肋条上，来实现结节的检测。 肋骨作为测量效果的放大器发挥作用。 该装置能够客观地检测乳房中肿块的存在并提供警告信号。 本发明的另一个实施例是用于对检查的乳房的机械结构进行成像并诊断伴随乳腺组织的弹性变化的疾病的临床装置。 该实施例由结合到患者支撑床中的电子控制机械扫描单元组成。 机械扫描单元包括压缩机构和定位系统，与压力传感器阵列相对的局部压力源，以及电子控制和接口电路。 局部压力源是在检查的乳房上移动的辊，或者在另一个实施例中，可以在所有三维中移动并由计算机自动或由鼠标手动控制的压头。 在另一个实施例中，机械扫描系统用作活组织检查引导装置，并确定由活检枪或抽吸针到达的乳房中的目标病变。

公开(公告)号：US4870970A

公开(公告)日：1989-10-03

申请号：US190689

申请日：1988-05-06

申请人： Nigel Gray ,  Simon Knibbs ,  Patrick A. Finlay ,  Robert L. Crocker

发明人： Nigel Gray ,  Simon Knibbs ,  Patrick A. Finlay ,  Robert L. Crocker

IPC分类号： A61B8/08

CPC分类号： A61B8/0825 ,  A61B8/0866 ,  A61B8/406 ,  Y10S128/915

摘要： An apparatus for transmitting acoustic ultrasonic pulses and for receiving "echos" of the transmitted pulses, comprises a housing, an upstanding wall mounted on the housing defining the mouth of a well, and a transducer mounted in the housing so that the operative part of the transducer is located in the well. The well is substantially watertight and is provided with a jet for introducing water or other fluids to the well, or is pre-filled with fluid.

摘要翻译： PCT No.PCT / GB87 / 00570 Sec。 371日期：1988年5月6日 102（e）日期1988年5月6日PCT提交1987年8月12日PCT公布。 公开号WO88 / 01151 日期：1988年2月25日。一种用于传输声学超声波脉冲并用于接收传输脉冲的“回波”的装置，包括壳体，安装在限定井口的壳体上的直立壁和安装在壳体中的换能器 使得换能器的操作部分位于井中。 井基本上是水密的，并且设置有用于将水或其它流体引入井的喷射器，或者预先填充流体。

公开(公告)号：US4478083A

公开(公告)日：1984-10-23

申请号：US503437

申请日：1983-06-13

申请人： Dieter Hassler ,  Elmar Trautenberg

发明人： Dieter Hassler ,  Elmar Trautenberg

IPC分类号： G01S15/88 ,  A61B8/00 ,  A61B8/08 ,  A61B8/14 ,  G01N29/04 ,  G01N29/00

CPC分类号： A61B8/0825 ,  A61B8/14 ,  A61B8/406 ,  Y10S128/915

摘要： An ultrasound tomography device for scanning an object under examination from a plurality of directions. Coronal slice images of the plane areas near or at the female breast wall are obtained. Ultrasound lobes from ultrasound transducers are electronically directed or mechanically positioned to obliquely strike the coronal slice located at or near the breast wall. A full image of the coronal slice plane is reconstructed through section by section combination of the images obtained from the several ultrasound lobes.

摘要翻译： 一种用于从多个方向扫描检查对象的超声断层摄影装置。 获得女性乳房壁附近或在女性胸壁上的平面区域的冠状切片图像。 来自超声波换能器的超声波瓣以电子方式或机械定位以倾斜地撞击位于胸壁或其附近的冠状切片。 通过从几个超声波瓣获得的图像的部分组合来重建冠状切片平面的完整图像。

公开(公告)号：US4455872A

公开(公告)日：1984-06-26

申请号：US480830

申请日：1983-04-25

申请人： George Kossoff ,  Jack Jellins

发明人： George Kossoff ,  Jack Jellins

IPC分类号： A61B8/00 ,  A61B8/08 ,  G01N29/04 ,  G01N29/06 ,  G01N29/28 ,  G10K11/35

CPC分类号： G10K11/352 ,  A61B8/0825 ,  A61B8/406 ,  A61B8/4209 ,  G01N29/0609 ,  Y10S128/915

摘要： A rotating scanner for use in ultrasonic echoscopy has a linearly scanned transducer arrangement, for transmitting beams of ultrasonic energy into an object (and receiving reflected ultrasonic echoes from the object). The transducer arrangement is rotated about an axis passing through the center or one end of the linear scan. The linear scanning may be mechanical scanning, or by electronic switching of an array of transducer elements.

摘要翻译： 用于超声波回波检查的旋转扫描器具有线性扫描的换能器装置，用于将超声能量的束发射到物体中（并且从物体接收反射的超声回波）。 换能器装置围绕穿过线性扫描的中心或一端的轴旋转。 线性扫描可以是机械扫描，或通过换能器元件阵列的电子切换。