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    Intracorporeal medicaments for high energy phototherapeutic treatment of disease
    42.
    发明申请
    Intracorporeal medicaments for high energy phototherapeutic treatment of disease 审中-公开
    用于高能量光疗治疗疾病的体内药物

    公开(公告)号：US20070078076A1

    公开(公告)日：2007-04-05

    申请号：US11542533

    申请日：2006-10-02

    申请人： H. Dees ,  Timothy Scott ,  Eric Wachter ,  Walter Fisher ,  John Smolik

    发明人： H. Dees ,  Timothy Scott ,  Eric Wachter ,  Walter Fisher ,  John Smolik

    IPC分类号： A61N5/00 ,  A61K48/00 ,  A61K38/17 ,  A61K31/365

    CPC分类号： A61K41/0038 ,  A61B2017/00057 ,  A61B2017/22062 ,  A61B2017/22087 ,  A61F7/00 ,  A61K9/0019 ,  A61K31/352 ,  A61K41/0057 ,  A61K41/008 ,  A61K47/10 ,  A61K47/12 ,  A61K47/20 ,  A61K47/6803 ,  A61K49/0041 ,  A61K49/0433 ,  A61N5/0601 ,  A61N5/062 ,  C07D311/82 ,  Y10S436/813 ,  Y10S436/819

    摘要： New intracorporeal radiodense medicaments and certain medical uses and methods for use of such high energy phototherapeutic medicaments for treatment of human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. The halogenated xanthenes constitute a family of potent radiosensitizers that become photoactivated upon irradiation of the treatment site with ionizing radiation. In embodiments of the present invention, such medicaments are used for treatment of a variety of conditions affecting the skin and related organs, the mouth and digestive tract and related organs, the urinary and reproductive tracts and related organs, the respiratory tract and related organs, the circulatory system and related organs, the head and neck, the endocrine and lymphoreticular systems and related organs, various other tissues, such as connective tissues and various tissue surfaces exposed during surgery, as well as various tissues exhibiting microbial or parasitic infection In another embodiment, such medicaments are produced in various formulations including liquid, semisolid, solid or aerosol delivery vehicles.

    摘要翻译： 描述了新的体内放射碘化物药物和用于治疗人或动物组织的这种高能光疗药物的某些医学用途和方法，其中这种药物的主要活性成分是卤代呫吨或卤化呫吨衍生物。 卤化呫吨构成了一种有效的放射增敏剂，其在用电离辐射照射治疗部位时变得光活化。 在本发明的实施方案中，这些药物用于治疗影响皮肤和相关器官，口腔和消化道及相关器官，泌尿生殖道和相关器官，呼吸道及相关器官的各种病症， 循环系统和相关器官，头颈部，内分泌和淋巴系统和相关器官，各种其他组织，例如在手术期间暴露的结缔组织和各种组织表面，以及显示微生物或寄生虫感染的各种组织。 ，这些药物是以各种制剂生产的，包括液体，半固体，固体或气溶胶递送载体。

    Catheters and methods of using catheters
    43.
    发明授权
    Catheters and methods of using catheters 有权
    导管和使用导管的方法

    公开(公告)号：US07131963B1

    公开(公告)日：2006-11-07

    申请号：US10184859

    申请日：2002-06-27

    申请人： Gregory Matthew Hyde

    发明人： Gregory Matthew Hyde

    IPC分类号： A61M29/00

    CPC分类号： A61M25/10 ,  A61B17/22 ,  A61B2017/22085 ,  A61B2017/22087 ,  A61M25/1002 ,  A61M2025/105 ,  A61M2025/1095 ,  A61N5/0601 ,  A61N5/062

    摘要： A catheter device and method, in which a first lumen coupled to a balloon, a second lumen coupled to the first lumen, the second lumen having a distal opening to dispense an oxygenated infusate, and a third lumen coupled to the second lumen and coupled to a second balloon. The second balloon restricts the flow of the oxygenated infusate, and the oxygenated infusate provides oxygen to tissue at a distal end of said catheter device.

    摘要翻译： 一种导管装置和方法，其中联接到气囊的第一腔，耦合到第一腔的第二腔，第二腔具有远端开口以分配氧合灌注液，以及联接到第二腔的第三腔， 第二个气球。 第二气囊限制氧合灌注液的流动，并且氧合的输注液在所述导管装置的远端向组织提供氧气。

    Medicaments for chemotherapeutic treatment of disease
    48.
    发明申请
    Medicaments for chemotherapeutic treatment of disease 审中-公开

    公开(公告)号：US20030133940A1

    公开(公告)日：2003-07-17

    申请号：US10331735

    申请日：2002-12-30

    申请人： Photogen, Inc.

    发明人： H. Craig Dees ,  Timothy C. Scott

    IPC分类号： A61K039/395 ,  A61K031/353 ,  A61K048/00

    CPC分类号： A61K41/0057 ,  A61B2017/22062 ,  A61B2017/22087 ,  A61F7/00 ,  A61K9/0014 ,  A61K9/0019 ,  A61K31/352 ,  A61K41/0071 ,  A61K47/10 ,  A61K47/12 ,  A61K47/20 ,  A61N5/0601 ,  A61N5/062 ,  C07D311/82 ,  Y02A50/473 ,  Y10T436/193333

    摘要： New chemotherapeutic medicaments and certain medical uses and methods for use of such chemotherapeutic medicaments for treatment of disease in human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. Preferably, the halogenated xanthene is Rose Bengal or a functional derivative of Rose Bengal. The halogenated xanthenes constitute a family of useful chemotherapeutic agents that afford selective, persistent accumulation in certain tissues. In preferred embodiments, such medicaments are used for treatment of a variety of conditions affecting the skin and related organs, the mouth and digestive tract and related organs, the urinary and reproductive tracts and related organs, the respiratory tract and related organs, the circulatory system and related organs, the head and neck, the endocrine and lymphoreticular systems and related organs, various other tissues, such as connective tissues and various tissue surfaces exposed during surgery, as well as various tissues exhibiting microbial or parasitic infection. In another preferred embodiment, such medicaments are produced in various formulations useful for intracorporeal or topical administration, including in liquid, semisolid, solid or aerosol delivery vehicles.