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    Ethanolaminephosphate cytidylyltransferase gene and promoter
    31.
    发明申请
    Ethanolaminephosphate cytidylyltransferase gene and promoter 审中-公开
    乙醇氨基磷酸胞苷酰转移酶基因和启动子

    公开(公告)号：US20040038360A1

    公开(公告)日：2004-02-26

    申请号：US10392837

    申请日：2003-03-21

    发明人： Marica Bakovic ,  Arkadi Poloumienko

    IPC分类号： C07H021/04 ,  C12N009/10 ,  C12P021/02 ,  C12N005/06 ,  C07K016/40

    CPC分类号： C12N9/1241

    摘要： The invention provides a gene encoding a protein having ethanolaminephosphate cytidylyltransferase activity, and a promoter of an ethanolaminephosphate cytidylyltransferase gene. Nucleotide sequences according to SEQ ID NO: 1 and SEQ ID NO: 2 relate to the gene and the promoter, respectively. An antibody against mECT peptide (SEQ ID NO: 53) is also provided.

    摘要翻译： 本发明提供编码具有乙醇氨基磷酸胞苷酰基转移酶活性的蛋白质的基因和乙醇氨基磷酸胞苷酰转移酶基因的启动子。 根据SEQ ID NO：1和SEQ ID NO：2的核苷酸序列分别涉及基因和启动子。 还提供了针对mECT肽（SEQ ID NO：53）的抗体。

    Herbicides test method
    32.
    发明申请
    Herbicides test method 审中-公开
    除草剂试验方法

    公开(公告)号：US20040033577A1

    公开(公告)日：2004-02-19

    申请号：US10456684

    申请日：2003-06-05

    发明人： Christopher Abell ,  Alison Gail Smith ,  Ulrich Genschel ,  Bernd Laber

    IPC分类号： C12N009/10 ,  C07H021/04 ,  C12P021/02 ,  C12N005/04

    CPC分类号： C12N9/93 ,  A01N61/00 ,  C12N15/8274 ,  G01N33/573

    摘要： An isolated DNA molecule encoding a protein from a plant, which protein has pantothenate synthetase activity; a non-naturally occuring chimeric gene comprising a promoter operably linked to a DNA molecule encoding a protein from a plant having pantothenate synthetase activity; a recombinant vector comprising the chimeric gene wherein the vector is capable of being stably transformed into host cell, a host cell stably transformed with a vector wherein the host cell is capable of expressing the DNA molecule; a method for assaying a protein having pantothenate synthetase activity; the use as herbicides of compounds which inhibit pantothenate synthetase, and a herbicidal composition, comprising one or more active ingredients which show significant pantothenate synthetase inhibition in an assay, are disclosed.

    摘要翻译： 编码来自植物的蛋白质的分离的DNA分子，该蛋白质具有泛酸合成酶活性; 非天然存在的嵌合基因，其包含与编码具有泛酸合成酶活性的植物的蛋白质的DNA分子可操作地连接的启动子; 包含嵌合基因的重组载体，其中所述载体能够稳定转化到宿主细胞中，宿主细胞用宿主细胞能够表达DNA分子的载体稳定转化; 测定具有泛酸合成酶活性的蛋白质的方法; 公开了用作抑制泛酸合成酶的化合物的除草剂的用途，以及包含在测定中显示出显着的泛酸合成酶抑制的一种或多种活性成分的除草组合物。

    Directing the ration of B2:B1 avermectins in Streptomyces avermitilis host cells
    34.
    发明申请
    Directing the ration of B2:B1 avermectins in Streptomyces avermitilis host cells 审中-公开
    引导B2：B1阿维菌素在阿维链霉菌寄主细胞中的比例

    公开(公告)号：US20040009560A1

    公开(公告)日：2004-01-15

    申请号：US10412444

    申请日：2003-06-11

    申请人： Pfizer Inc.

    发明人： Kim J. Stutzman-Engwall ,  Chen Yan ,  Claes Gustafsson ,  Anke Krebber ,  Jeremy Minshull ,  Sun Ai Raillard

    IPC分类号： C12P019/62 ,  C07H021/04 ,  C12N009/10 ,  C12N001/21 ,  C12P021/02 ,  C12N015/74

    CPC分类号： C12P17/181 ,  C12N9/88 ,  C12P19/623

    摘要： The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of S. avermitilis. The present invention further relates to vectors, host cells, and mutant strains of S. avermitilis in which the aveC gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.

    摘要翻译： 本发明涉及包含编码aveC基因产物的核苷酸序列的多核苷酸分子，所述多核苷酸分子可用于改变阿维链霉菌发酵培养物中产生的2:1级阿凡曼菌素的比例或量。 本发明还涉及阿维链霉菌的载体，宿主细胞和突变菌株，其中aveC基因已被灭活，或突变以改变所产生的2:1级除虫菌素的比例或量。

    Phosphoribosylaminoimidazole carboxylase
    38.
    发明申请
    Phosphoribosylaminoimidazole carboxylase 审中-公开
    磷脂酰氨基咪唑羧化酶

    公开(公告)号：US20030229916A1

    公开(公告)日：2003-12-11

    申请号：US10323167

    申请日：2002-12-19

    发明人： Stephen M. Allen ,  Emil M. Orozco JR. ,  Jian-Ming Lee

    IPC分类号： A01H001/00 ,  C12N015/82 ,  C07H021/04 ,  C12N009/10 ,  C12P021/02 ,  C12N005/04

    CPC分类号： C12Y401/01021 ,  C12N9/88

    摘要： This invention relates to an isolated nucleic acid fragment encoding a phosphoribosylaminoimidazole carboxylase. The invention also relates to the construction of a recombinant DNA construct or chimeric gene encoding all or a portion of the phosphoribosylaminoimidazole carboxylase, in sense or antisense orientation, wherein expression of the recombinant DNA construct or chimeric gene results in production of altered levels of the phosphoribosylaminoimidazole carboxylase in a transformed host cell.

    摘要翻译： 本发明涉及编码磷酸核糖基氨基咪唑羧化酶的分离的核酸片段。 本发明还涉及在正义或反义方向上构建编码全部或一部分磷酸核糖基氨基咪唑羧化酶的重组DNA构建体或嵌合基因，其中重组DNA构建体或嵌合基因的表达导致产生改变的磷酸核糖基氨基咪唑水平 羧化酶在转化的宿主细胞中。

    Nucleotide sequences encoding the ptsH gene
    39.
    发明申请
    Nucleotide sequences encoding the ptsH gene 有权

    公开(公告)号：US20030224499A9

    公开(公告)日：2003-12-04

    申请号：US09819930

    申请日：2001-03-29

    发明人： Mike Farwick ,  Bettina Mockel ,  Walter Pfefferle

    IPC分类号： C12P013/08 ,  C12P021/02 ,  C12N001/21 ,  C07H021/04 ,  C12N009/10 ,  C12N015/74

    CPC分类号： C12N9/1205 ,  C12P13/04 ,  C12P13/08

    摘要： The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide containing an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative production of L-amino acids with enhancement of the ptsH gene coding for component H of the phosphotransferase system, and the use of the above polynucleotides as primer or hybridisation probe.

    Compositions, methods and systems for discovery of lipopeptides
    40.
    发明申请
    Compositions, methods and systems for discovery of lipopeptides 审中-公开
    用于发现脂肽的组合物，方法和系统

    公开(公告)号：US20030211567A1

    公开(公告)日：2003-11-13

    申请号：US10329027

    申请日：2002-12-24

    申请人： Ecopia Biosciences, Inc.

    发明人： Chris M. Farnet ,  Alfredo Staffa ,  Emmanuel Zazopoulos

    IPC分类号： C12P021/06 ,  C07H021/04 ,  C12N009/10 ,  C12N001/21 ,  C12N015/74

    CPC分类号： C07K14/365 ,  C07K14/36 ,  C12N15/52

    摘要： The invention relates to isolated polypeptides involved in lipopeptide biosynthesis and polynucleotides encoding such polypeptides. In particular, the isolated polypeptide may be an acyl-specific C-domain, an adenylating enzyme, or an acyl carrier. The invention also relates to methods for detecting a polypeptide involved in lipopeptide biosynthesis or a polynucleotide encoding such a polypeptide, as well as relevant useful computer readable medium and computer systems.

    摘要翻译： 本发明涉及参与脂肽生物合成的分离的多肽和编码这些多肽的多核苷酸。 特别地，分离的多肽可以是酰基特异性C-结构域，腺苷酸化酶或酰基载体。 本发明还涉及用于检测参与脂肽生物合成的多肽的方法或编码这种多肽的多核苷酸，以及相关的有用的计算机可读介质和计算机系统。