公开(公告)号：US20190001129A1

公开(公告)日：2019-01-03

申请号：US16020876

申请日：2018-06-27

申请人： Cala Health, Inc.

发明人： Kathryn H. Rosenbluth ,  Scott Lee Delp ,  John Paderi ,  Vijaykumar Rajasekhar ,  Tahel Altman ,  Samuel Richard Hamner ,  Erika Kristine Ross

IPC分类号： A61N1/36 ,  A61N1/18 ,  A61N1/08 ,  A61N1/02 ,  A61N1/04

摘要： A peripheral nerve stimulator to stimulate a peripheral nerve to treat essential tremor and other movement disorders, as well as overactive bladder, cardiac dysfunction and neurotransmitter dysfunction is provided. The peripheral nerve stimulator can be a noninvasive surface stimulator to provide multi-modal optimized therapy. Stimulation can be vibrational, electromechanical, thermal, radiant, electrical, magnetic, electromagnetic, light, mechanical, chemical, thermal, ultrasonic, radiofrequency (RF), acoustic, infrared, ultraviolet, x-ray, and/or microwave. Stimulation can be delivered using an open loop system and/or a closed loop system with feedback. Stimulation can be to one site or multiple sites.

公开(公告)号：US20180264263A1

公开(公告)日：2018-09-20

申请号：US15983024

申请日：2018-05-17

申请人： Cala Health, Inc.

发明人： Kathryn H. Rosenbluth ,  Scott Lee Delp ,  John Paderi ,  Vijaykumar Rajasekhar ,  Tahel Altman

IPC分类号： A61N1/36 ,  A61N1/18 ,  A61N1/08 ,  A61N1/02 ,  A61N1/04

CPC分类号： A61N1/36014 ,  A61N1/025 ,  A61N1/0456 ,  A61N1/0476 ,  A61N1/0492 ,  A61N1/08 ,  A61N1/18 ,  A61N1/36067

摘要： A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinson tremor, and other forms of tremor. The peripheral nerve stimulator can be either a noninvasive surface stimulator or an implanted stimulator. Stimulation can be electrical, mechanical, or chemical. Stimulation can be delivered using either an open loop system or a closed loop system with feedback.

公开(公告)号：US20180229033A1

公开(公告)日：2018-08-16

申请号：US15946919

申请日：2018-04-06

申请人： Medtronic Ardian Luxembourg S.a.r.l.

发明人： Mark E. Deem ,  Hanson Gifford, III ,  Denise Zarins ,  Douglas Sutton ,  Erik Thai ,  Mark Gelfand ,  Howard R. Levin

IPC分类号： A61N1/36 ,  A61N1/20 ,  A61N1/18 ,  A61B18/00

CPC分类号： A61N1/36007 ,  A61B8/0891 ,  A61B8/12 ,  A61B18/1206 ,  A61B18/1233 ,  A61B18/1492 ,  A61B18/18 ,  A61B2018/00071 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00642 ,  A61B2018/00904 ,  A61B2018/126 ,  A61B2018/1467 ,  A61M5/14 ,  A61M25/0023 ,  A61N1/0412 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/18 ,  A61N1/205 ,  A61N1/326 ,  A61N1/327 ,  A61N1/36017 ,  A61N1/36057 ,  A61N1/3606 ,  A61N1/36103 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/36139 ,  A61N5/00 ,  A61N7/00 ,  A61N2007/0021 ,  A61N2007/003

摘要： Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.

公开(公告)号：US10046160B1

公开(公告)日：2018-08-14

申请号：US13630513

申请日：2012-09-28

申请人： Nu Skin Enterprises, Inc.

发明人： Dale G. Kern

IPC分类号： A61N1/36 ,  A61N7/00 ,  A61N1/18 ,  A61N1/32

摘要： Disclosed is a method for treating dermis and hypodermis by placing at least a first electrode at the surface of a to-be-treated skin region and contacting a second electrode at another position on the body to be treated then applying between the electrodes a current with pulse component, said current being sufficient to produce electro-osmotic pressure/velocity wavefronts corresponding to the fundamental frequency in blood vessels in the dermis and hypodermis of the skin region.

公开(公告)号：US20180214692A1

公开(公告)日：2018-08-02

申请号：US15915255

申请日：2018-03-08

申请人： MORDECHAY ESH ,  GIORA ARBEL

发明人： MORDECHAY ESH ,  GIORA ARBEL

IPC分类号： A61N1/36 ,  A61N1/32 ,  A61N1/04 ,  A61N1/18

摘要： A non-invasive method and device for treating gastroesophageal reflux disease (GERD) in a patient are disclosed. The method calls for positioning electrodes, and applying electrical symmetrical bursts. In particular, positioning step requires positioning a plurality of electrodes in electrical contact with the skin of a target region of the abdomen of the patient. The application step calls for applying a series of electrical symmetrical bursts to said electrodes. That application step generates contractions of abdominal muscles thereby generating movements of a digestive system of said patient wherein said movements are for causing the content of the esophagus to return to the stomach and to relieve GERD symptoms of said patient.

公开(公告)号：US09931045B2

公开(公告)日：2018-04-03

申请号：US13969096

申请日：2013-08-16

申请人： Medtronic Xomed, Inc.

发明人： William C. Brunnett ,  David C. Hacker ,  Carla A. Pagotto ,  Denise Grant

IPC分类号： A61B5/04 ,  A61N1/18 ,  A61B5/0488 ,  A61B5/0492 ,  A61N1/05 ,  A61B5/00

CPC分类号： A61B5/04001 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/4041 ,  A61N1/0551 ,  A61N1/0556

摘要： A nerve electrode cuff includes an electrode and a cuff body.

公开(公告)号：US20180078757A1

公开(公告)日：2018-03-22

申请号：US15707185

申请日：2017-09-18

申请人： Robert Madeira

发明人： Robert Madeira

IPC分类号： A61N1/05 ,  A61N1/36 ,  A61N1/18 ,  A61F2/38 ,  A61F2/60 ,  A61F2/08 ,  A61F2/30 ,  A61F2/00 ,  A61F2/02

摘要： A system and method for improving limb function through the use of percutaneous mechanical and neural interfaces. The system generally uses a hollow long bone axial rod that is inserted into the long bone medullary cavity. A transfer rod with a central channel is mounted to the long bone axial rod. An exterior body attachment is connected to the transfer rod and attachment rings attach muscle groups, fascia layers and dermal layers to the transfer rod. Additionally, the system is configured to collect and transmit nerve signaling data to an external processor and additionally configured to transmit data from the external processor to the plurality of nerves.

公开(公告)号：US09884187B2

公开(公告)日：2018-02-06

申请号：US15439415

申请日：2017-02-22

申请人： THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

发明人： Paul B. Yoo ,  Michael Sasha John

IPC分类号： A61N1/05 ,  A61N1/18 ,  A61N1/36 ,  A61N1/04 ,  A61N2/00 ,  A61N2/02

CPC分类号： A61N1/36007 ,  A61N1/0456 ,  A61N1/0502 ,  A61N1/0553 ,  A61N1/0556 ,  A61N1/36017 ,  A61N1/3606 ,  A61N1/36107 ,  A61N2/006 ,  A61N2/02

摘要： A method to treat a patient having a pelvic floor dysfunction or disorder by establishing a neurostimulator having a processor and an electrical signal generator to generate a stimulation signal. The processor is set to one or more parameters effective in the treating of the patient's pelvic disorder or dysfunction when the stimulation signal is applied to a saphenous nerve of the patient. The neurostimulator is configured to provide the stimulation signal to a stimulator in accordance with a stimulation protocol. The stimulator is positioned below or at the level of the patient's knee and next to a portion of the saphenous nerve. The processor is operationally activated to provide the stimulation signal to the stimulator for treatment of the patient.

公开(公告)号：US09884181B2

公开(公告)日：2018-02-06

申请号：US15212238

申请日：2016-07-17

申请人： Rapid Orthodontics, Inc.

发明人： Zeev Davidovitch ,  Robert Sanford ,  Moshe Davidovitch

IPC分类号： A61C3/00 ,  A61N1/05 ,  A61N1/18 ,  A61C19/04 ,  A61B5/145 ,  A61C7/00 ,  A61C7/08 ,  A61C7/14 ,  A61C7/20 ,  A61N1/20 ,  A61C19/06 ,  A61N1/08 ,  A61N1/28 ,  A61N1/30

CPC分类号： A61N1/0548 ,  A61B5/14539 ,  A61C7/00 ,  A61C7/08 ,  A61C7/14 ,  A61C7/20 ,  A61C19/04 ,  A61C19/063 ,  A61N1/08 ,  A61N1/18 ,  A61N1/205 ,  A61N1/28 ,  A61N1/306

摘要： A vestibular electronic orthodontic appliance expediter constituted of a lingual sub-member and a buccal sub-member, the lingual sub-member arranged to fit a lingual contour of a gum of a patient, the buccal sub-member arranged to fit a buccal contour of a gum of the patient; a control circuitry; a power supply; a plurality of lingual electrodes, each associated with a particular tooth socket; and a plurality of buccal electrodes, each associated with a particular tooth socket. Either a first or a second type current is generated between lingual and buccal electrodes responsive to the control circuitry. Biochemical molecules involved in bone remodeling, augmented by the electric currents, may be applied to the expediter as a layer of gel containing those molecules on the expediter surface facing the gum tissue. Temperature control enhances the gel effects. pH measurement, as indicators of the cellular response to the combined treatment is further provided.

公开(公告)号：US09833619B2

公开(公告)日：2017-12-05

申请号：US12285791

申请日：2008-10-14

申请人： Peter Forsell

发明人： Peter Forsell

IPC分类号： A61N1/18 ,  A61N1/36 ,  A61M1/12 ,  A61N1/05 ,  A61F2/00 ,  A61M1/10 ,  A61N1/378

CPC分类号： A61N1/36007 ,  A61F2/004 ,  A61M1/1056 ,  A61M1/106 ,  A61M1/1067 ,  A61M1/12 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/8243 ,  A61N1/0507 ,  A61N1/3787

摘要： There is provided a method for treating a male impotent patient comprising stimulating at least one portion of the patient's normal penile tissue or the prolongation thereof to at least restrict the blood flow leaving the penis to achieve erection. To improve the erection effect the method further comprises gently constricting the penile portion or the prolongation thereof to restrict the venous blood flow in the penile portion, and then stimulating the constricted penile portion to cause contraction of the penile portion to at least further restrict the blood flow leaving the penis to achieve erection.