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公开(公告)号：US10059768B2
公开(公告)日：2018-08-28
申请号：US14851003
申请日：2015-09-11
Applicant: Genentech, Inc.
Inventor： Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , C07K16/30 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , G01N33/574 , A61K47/68
CPC classification number: C07K16/2827 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/6803 , A61K47/6809 , A61K47/6855 , A61K47/6869 , A61K2039/505 , C07K16/3015 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20160159910A1
公开(公告)日：2016-06-09
申请号：US14851003
申请日：2015-09-11
Applicant: GENENTECH, INC.
Inventor： Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K31/5517 , A61K31/706 , G01N33/574 , A61K47/48 , C07K16/22 , A61K51/10 , A61K38/05 , A61K31/404
CPC classification number: C07K16/2827 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/6803 , A61K47/6809 , A61K47/6855 , A61K47/6869 , A61K2039/505 , C07K16/3015 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号：US20160017040A1
公开(公告)日：2016-01-21
申请号：US14773334
申请日：2014-03-13
Applicant: GENENTECH, INC.
Inventor： Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/48 , G01N33/569 , A61K39/395 , A61K51/10 , C07K16/30 , A61K38/08
CPC classification number: C07K16/2827 , A61K38/08 , A61K39/39558 , A61K47/65 , A61K47/6801 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K51/1027 , A61K51/1051 , A61K2039/505 , C07K16/3015 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/56972
Abstract: The disclosure provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本公开提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号：US09175089B2
公开(公告)日：2015-11-03
申请号：US13853620
申请日：2013-03-29
Applicant: GENENTECH INC.
Inventor： Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗LgR5抗体和免疫缀合物及其使用方法。
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35.发明申请COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH A CD22 ANTIBODY-DRUG CONJUGATE 审中-公开具有CD22抗体药物结合的抗原性CD20抗体的组合疗法公开(公告)号：US20150010540A1
公开(公告)日：2015-01-08
申请号：US14265857
申请日：2014-04-30
Applicant: HOFFMANN-LA ROCHE INC. , GENENTECH, INC.
Inventor： Christian Klein , Sabine Lang , Pablo Umana , Andrew Polson
IPC: C07K16/28 , A61K45/06 , A61K47/48 , A61K39/395
Abstract: The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD22 antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD22 antibody-drug conjugate.
Abstract translation: 本发明涉及非糖蛋白化抗CD20抗体与用于治疗癌症的CD22抗体 - 药物偶联物的组合疗法，特别是与非糖蛋白化人源化B-Ly1抗体和CD22抗体的CD20表达癌症的组合疗法 药物结合物。
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Patent Agency Ranking
36.发明申请COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH A CD79b ANTIBODY-DRUG CONJUGATE 审中-公开具有CD79b抗体药物结合的胶原蛋白CD20抗体的组合治疗公开(公告)号：US20140356352A1
公开(公告)日：2014-12-04
申请号：US14266443
申请日：2014-04-30
Applicant: Hoffmann-La Roche Inc. , Genentech, Inc.
Inventor： Christian Klein , Sabine Lang , Pablo Umana , Andrew Polson
IPC: A61K39/395 , A61K31/40 , A61K31/5365 , A61K45/06 , C07K16/28 , A61K47/48
Abstract: The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD79b antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD79b antibody-drug conjugate.
Abstract translation: 本发明涉及非岩藻糖基化抗CD20抗体与用于治疗癌症的CD79b抗体 - 药物偶联物的组合疗法，特别是与非糖蛋白化人源化B-Ly1抗体和CD79b抗体的CD20表达癌症的组合疗法 药物结合物。
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37.发明申请公开(公告)号：US20140106374A1
公开(公告)日：2014-04-17
申请号：US14078241
申请日：2013-11-12
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: G01N33/68
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20140030279A1
公开(公告)日：2014-01-30
申请号：US13936279
申请日：2013-07-08
Applicant: Spirogen Sari , Genentech, Inc.
Inventor： Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu , John A. Flygare , Janet L. Gunzner-Toste , Thomas Harden Pillow , Philip Wilson Howard , Luke Masterson
IPC: A61K47/48 , A61K45/06 , A61K31/551
CPC classification number: A61K31/5517 , A61K31/551 , A61K45/06 , A61K47/6809 , A61K47/6849 , A61K47/6867 , A61K47/6877 , A61K2300/00
Abstract: The invention provides anti-CD22 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US11866496B2
公开(公告)日：2024-01-09
申请号：US17234695
申请日：2021-04-19
Applicant: Genentech, Inc.
Inventor： Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
CPC classification number: C07K16/2803 , A61K39/39541 , A61K39/39558 , A61K47/6849 , A61K51/1027 , C07K16/2896 , C07K16/3061 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/92 , Y02A50/30
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20220251213A1
公开(公告)日：2022-08-11
申请号：US17677283
申请日：2022-02-22
Applicant: Genentech, Inc.
Inventor： Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/68 , C07K16/30 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , G01N33/574
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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