公开(公告)号：US08940540B2

公开(公告)日：2015-01-27

申请号：US13796093

申请日：2013-03-12

Applicant: Bayer Healthcare LLC

Inventor： Steven C. Charlton ,  Allen Brenneman

IPC: G01N33/66 ,  G01N35/00 ,  B01L3/00 ,  G01N33/543

CPC classification number: G01N33/48757 ,  G01N33/54386 ,  G01N33/66 ,  G01N2333/904 ,  Y10T436/112499 ,  Y10T436/114165 ,  Y10T436/143333 ,  Y10T436/144444 ,  Y10T436/146666

Abstract: A portable, hand-held glucose testing device includes a housing configured to accommodate a plurality of test sensors in a stacked arrangement and having a wall with an opening defined therein. A plurality of packaged test sensors is stacked in alignment with one another within the housing. Each of the test sensors is packaged within a blister package. The blister package includes a blister package housing and a cover foil overlying a surface of the blister package housing and the test sensor. A drive slide is configured to displace one of the plurality of packaged test sensors out of alignment with other packaged test sensors. A knife mechanism is configured to pierce through the cover foil, and to engage and urge the test sensor to extend through the opening for receiving a sample. A meter contact is configured to engage the test sensor when the test sensor extends through the opening.

公开(公告)号：US20140273041A1

公开(公告)日：2014-09-18

申请号：US13800799

申请日：2013-03-13

Applicant: BAYER HEALTHCARE LLC

Inventor： Steven C. Charlton

IPC: C12Q1/54

CPC classification number: G01N33/48757 ,  C12Q1/005 ,  C12Q1/54 ,  G01N21/8483 ,  G01N33/52 ,  G01N33/5438

Abstract: A device and system for automatic handling of a sensor strip by a part of meter includes a sensor strip having a first section, a second section, and an intermediate section. The sensor strip includes at least a first opening about a first end thereof and a second opening about a second end thereof. A meter part includes a pair of pivoting catches configured to engage and grasp a sensor strip from a container containing a plurality of sensor strips. The sensor strip may thus be removed from a container for testing without need for manual handling of the strip by a user.

Abstract translation: 用于通过仪表的一部分自动处理传感器条的装置和系统包括具有第一部分，第二部分和中间部分的传感器带。 传感器条包括至少围绕其第一端的第一开口和围绕其第二端的第二开口。 仪表部分包括一对枢转卡爪，其构造成从包含多个传感器条的容器接合并抓握传感器条。 因此，传感器条可以从用于测试的容器中移除，而不需要用户手动处理条带。

公开(公告)号：US20140193894A1

公开(公告)日：2014-07-10

申请号：US14202843

申请日：2014-03-10

Applicant: Bayer Healthcare, LLC

Inventor： Sung-Kwon Jung ,  Steven C. Charlton ,  Suny J. George ,  Andrew J. Dosmann ,  Karen L. Marfurt

IPC: G01N33/66 ,  G01N33/52

CPC classification number: G01N33/66 ,  A61B5/1411 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150274 ,  A61B5/150343 ,  A61B5/150358 ,  A61B5/157 ,  A61B2562/242 ,  G01N21/78 ,  G01N33/521 ,  G01N33/528

Abstract: A fluid sensor comprises a formed plastic body and a reagent. The body has a top face with an integral first surface. The body also has a bottom face opposed to the first surface and a sidewall that extends from the periphery of the top face. The first surface is adapted to accept a fluid sample. The reagent is disposed on the integral first surface and causes a color change detectable on the bottom face when the reagent reacts with an analyte in the fluid sample.

Abstract translation: 流体传感器包括成形塑料体和试剂。 身体有一个整体表面的顶面。 主体还具有与第一表面相对的底面和从顶面的周边延伸的侧壁。 第一表面适于接受流体样品。 当试剂与流体样品中的分析物反应时，将试剂置于整体的第一表面上并引起底面上可检测到的颜色变化。

公开(公告)号：US20130270123A1

公开(公告)日：2013-10-17

申请号：US13872531

申请日：2013-04-29

Applicant: Bayer HealthCare LLC

Inventor： Sung-Kwon Jung ,  Steven C. Charlton ,  Dija Huang

IPC: C25D11/02

CPC classification number: C25D11/02 ,  C12Q1/001 ,  G01N27/3272 ,  Y10T29/49117

Abstract: Systems and methods for electrochemically oxidizing components of a test-sensor reagent prior to deposition on a test sensor comprise at least a first electrode and a second electrode for contacting the test-sensor reagent. The first electrode and the second electrode may have hollow interior portions for contacting the test-sensor reagent to produce a modified test-sensor reagent having a reduced background current.

Abstract translation: 在测试传感器上沉积之前对测试传感器试剂的组分进行电化学氧化的系统和方法包括用于接触测试传感器试剂的至少第一电极和第二电极。 第一电极和第二电极可以具有用于接触测试传感器试剂以产生具有降低的背景电流的修改的测试传感器试剂的中空内部部分。

公开(公告)号：US10329684B2

公开(公告)日：2019-06-25

申请号：US14737269

申请日：2015-06-11

Applicant: Bayer HealthCare LLC

Inventor： Sung-Kwon Jung ,  Dijia Huang ,  Steven C. Charlton

IPC: C12Q1/00 ,  G01N27/26 ,  C25D11/02 ,  G01N27/327

Abstract: Systems and methods for electrochemically oxidizing components of a test-sensor reagent prior to deposition on a test sensor comprise at least a first electrode and a second electrode for contacting the test-sensor reagent. The first electrode and the second electrode may have hollow interior portions for contacting the test-sensor reagent to produce a modified test-sensor reagent having a reduced background current.

公开(公告)号：US09678034B2

公开(公告)日：2017-06-13

申请号：US14935256

申请日：2015-11-06

Applicant: BAYER HEALTHCARE LLC

Inventor： Steven C. Charlton

IPC: G01N27/327 ,  G01N33/487 ,  G01N27/416

CPC classification number: G01N27/3273 ,  G01N27/3272 ,  G01N27/4166 ,  G01N33/48707 ,  G01N33/48757 ,  G01N33/48778 ,  G01N33/48785 ,  Y10T29/49826

Abstract: In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a biological fluid sample. The analyte sensor has a base including a top and bottom side, a lid, and an attachment member including one or more retention tabs coupled proximate the top side so that the analyte sensor can be grasped by the sensor's top side. Manufacturing methods and systems adapted to use and dispense the analyte sensors are provided, as are numerous other aspects.

公开(公告)号：US20150260677A1

公开(公告)日：2015-09-17

申请号：US14727315

申请日：2015-06-01

Applicant: Bayer HealthCare LLC

Inventor： Sung-Kwon Jung ,  Dijia Huang ,  Steven C. Charlton

IPC: G01N27/327

CPC classification number: C25D11/02 ,  C12Q1/001 ,  G01N27/3272 ,  Y10T29/49117

Abstract: Systems and methods for electrochemically oxidizing components of a test-sensor reagent prior to deposition on a test sensor comprise at least a first electrode and a second electrode for contacting the test-sensor reagent. The first electrode and the second electrode may have hollow interior portions for contacting the test-sensor reagent to produce a modified test-sensor reagent having a reduced background current.

Abstract translation: 在测试传感器上沉积之前对测试传感器试剂的组分进行电化学氧化的系统和方法包括用于接触测试传感器试剂的至少第一电极和第二电极。 第一电极和第二电极可以具有用于接触测试传感器试剂以产生具有降低的背景电流的修改的测试传感器试剂的中空内部部分。

公开(公告)号：US20150098866A1

公开(公告)日：2015-04-09

申请号：US14570613

申请日：2014-12-15

Applicant: Bayer HealthCare LLC

Inventor： Jeffery S. Reynolds ,  Steven C. Charlton ,  Sung-Kwon Jung ,  Suny J. George

IPC: G01N21/78

CPC classification number: G01N21/78 ,  G01N21/251 ,  G01N21/474 ,  G01N21/64 ,  G01N21/6486 ,  G01N21/7703 ,  G01N21/80 ,  G01N33/582 ,  G01N33/583 ,  G01N2021/772 ,  G01N2021/7773 ,  G01N2201/08 ,  Y10T156/1313 ,  Y10T436/144444

Abstract: An optic light guide test sensor comprises a light guide, a reagent-coated membrane, and a mesh layer. The reagent-coated membrane and the mesh layer are attached to the light guide at an output end of the light guide. The light guide test sensor is adapted to be used to test the level of an analyte in a biological fluid sample when used with a readhead. A method of manufacturing the light guide test sensor involves providing a plurality of light guides, providing a strip of reagent-coated membrane, and providing a strip of mesh layer. The reagent-coated membrane and mesh layer are attached to the light guides by ultrasonic welding. The reagent-coated membrane and mesh layer may also be attached to the light guides by adhesive.

Abstract translation: 光学导光测试传感器包括光导，试剂涂覆膜和网格层。 试剂涂布的膜​​和网状层在导光体的输出端附着于导光体。 当与读取​​头一起使用时，光导测试传感器适用于测试生物流体样品中分析物的水平。 制造光导测试传感器的方法包括提供多个光导，提供试剂涂覆膜条，并提供网格条带。 试剂涂布膜和网眼层通过超声波焊接附着于光导。 试剂涂布的膜​​和网格层也可以通过粘合剂附着到光导。

公开(公告)号：US20140227771A1

公开(公告)日：2014-08-14

申请号：US14255526

申请日：2014-04-17

Applicant: Bayer HealthCare LLC

Inventor： Swetha Chinnayelka ,  Jiangfeng Fei ,  Yuan Wang ,  Narasinha Parasnis ,  Hoi-Cheong Steve Sun ,  Raeann Gifford ,  Steven C. Charlton

IPC: G01N33/543 ,  G01N33/80 ,  G01N33/66

CPC classification number: G01N33/54373 ,  G01N33/66 ,  G01N33/80 ,  Y10T436/144444

Abstract: A test meter system for testing a characteristic of a fluid, the test meter system including a test meter having a housing with an opening adapted to accept a test strip, an interrogation coil within the housing, a pick-up coil within the housing, and a test strip including at least one magneto-elastic-resonance sensor. When the test strip is within the opening, the interrogation coil may utilize magneto-elastic-resonance technology to interrogate the magneto-elastic-resonance sensor and the pick-up coil may be used to sense a resultant oscillation frequency of the magneto-elastic-resonance sensor, the resultant oscillation frequency associated with the characteristic. The test strip may include a plurality of sensors. The sensors may be coated with a coating sensitive to a characteristic of the fluid, where the interrogation reveals information about the fluid characteristic.

Abstract translation: 一种用于测试流体特性的测试仪系统，所述测试计系统包括测试仪，所述测试仪器具有壳体，所述壳体具有适于接纳测试条的开口，所述壳体内的询问线圈，所述壳体内的拾取线圈，以及 包括至少一个磁弹性共振传感器的测试条。 当测试条在开口内时，询问线圈可以利用磁弹性共振技术来询问磁弹性共振传感器，并且拾取线圈可用于感测磁弹性共振传感器的合成振荡频率， 谐振传感器，产生的振荡频率与特性相关联。 测试条可以包括多个传感器。 传感器可以涂覆有对流体特性敏感的涂层，其中询问显示关于流体特性的信息。

公开(公告)号：US08715588B2

公开(公告)日：2014-05-06

申请号：US13975937

申请日：2013-08-26

Applicant: Bayer HealthCare, LLC

Inventor： Sung-Kwon Jung ,  Steven C. Charlton ,  Suny J. George ,  Andrew J. Dosmann ,  Karen L. Marfurt

IPC: G01N33/48

CPC classification number: G01N33/66 ,  A61B5/1411 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150274 ,  A61B5/150343 ,  A61B5/150358 ,  A61B5/157 ,  A61B2562/242 ,  G01N21/78 ,  G01N33/521 ,  G01N33/528

Abstract: A fluid sensor comprises a formed plastic body and a reagent. The body has a top face with an integral first surface. The body also has a bottom face opposed to the first surface and a sidewall that extends from the periphery of the top face. The first surface is adapted to accept a fluid sample. The reagent is disposed on the integral first surface and causes a color change detectable on the bottom face when the reagent reacts with an analyte in the fluid sample.

Abstract translation: 流体传感器包括成形塑料体和试剂。 身体有一个整体表面的顶面。 主体还具有与第一表面相对的底面和从顶面的周边延伸的侧壁。 第一表面适于接受流体样品。 当试剂与流体样品中的分析物反应时，将试剂置于整体的第一表面上并引起在底面上可检测到的颜色变化。