公开(公告)号：USD516570S1

公开(公告)日：2006-03-07

申请号：US29220425

申请日：2004-12-29

Applicant: Yun-Lung Chen ,  Qun Wang ,  Jin-Feng Yao ,  Jian-Hua He

Designer： Yun-Lung Chen ,  Qun Wang ,  Jin-Feng Yao ,  Jian-Hua He

公开(公告)号：USD505804S1

公开(公告)日：2005-06-07

申请号：US29193523

申请日：2003-11-12

Applicant: Feng Yao Chen

Designer： Feng Yao Chen

公开(公告)号：USD505031S1

公开(公告)日：2005-05-17

申请号：US29201823

申请日：2004-03-22

Applicant: Feng Yao Chen

Designer： Feng Yao Chen

公开(公告)号：US09273326B2

公开(公告)日：2016-03-01

申请号：US11117375

申请日：2005-04-29

Applicant: Feng Yao

Inventor： Feng Yao

IPC: C12N15/869 ,  C12N15/86

CPC classification number: C12N15/86 ,  A61K48/0008 ,  C07K14/005 ,  C12N7/00 ,  C12N15/635 ,  C12N2710/16643

Abstract: The present invention is directed to HSV-1 vectors which rely on the tetracycline repressor and operator as a means for regulating expression. The vectors utilize VP-16 responsive promoters of HSV to control expression of the tetracycline repressor. The vectors are of particular interest as vehicles for recombinantly expressing genes in vivo.

Abstract translation: 本发明涉及依赖于四环素阻遏物和操纵子作为调节表达的手段的HSV-1载体。 载体使用HSV的VP-16响应启动子来控制四环素阻遏物的表达。 载体作为在体内重组表达基因的载体是特别有意义的。

公开(公告)号：US08711093B2

公开(公告)日：2014-04-29

申请号：US12822352

申请日：2010-06-24

Applicant: Chi-Boon Ong ,  Yu-Feng Yao ,  Sze-Ping Ong

Inventor： Chi-Boon Ong ,  Yu-Feng Yao ,  Sze-Ping Ong

IPC: G06F3/033

CPC classification number: G06F3/033 ,  G06F3/0304 ,  G06F3/042

Abstract: Input devices configured to provide user interface by detecting three dimensional movement of an external object are disclosed. The input device comprises at least two photodetector pairs, a radiation source and a circuit configurable to detect differential and common mode signals generated in the photodetector pairs. By detecting the common mode and differential signals, movement of an external object may be determined and used to control a pointer, or a cursor.

Abstract translation: 公开了通过检测外部对象的三维运动来配置为提供用户界面的输入设备。 输入装置包括至少两个光电检测器对，辐射源和可配置为检测在光电检测器对中产生的差模和共模信号的电路。 通过检测共模和差分信号，可以确定外部对象的移动并用于控制指针或光标。

公开(公告)号：US20120190106A1

公开(公告)日：2012-07-26

申请号：US13392954

申请日：2010-08-20

Applicant: Feng Yao

Inventor： Feng Yao

IPC: C12N15/113 ,  C12N15/85

CPC classification number: C12N15/85 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/16122 ,  C12N2800/107 ,  C12N2830/60

Abstract: The present invention is directed to a bidirectional human cytomegalovirus (hCMV) promoter that can be used to promote transcription on both strands of a double stranded DNA molecule. When used as part of a system that includes tet operator and the gene coding for the tet repressor, the promoter can be used to induce mammalian gene expression in a highly regulated way.

Abstract translation: 本发明涉及可用于促进双链DNA分子的两条链上的转录的双向人巨细胞病毒（hCMV）启动子。 当用作包括tet操纵子和编码tet阻遏物的基因的系统的一部分时，启动子可以以高度调节的方式用于诱导哺乳动物基因表达。

公开(公告)号：US20110309530A1

公开(公告)日：2011-12-22

申请号：US12818750

申请日：2010-06-18

Applicant: Guo Qiang Shen ,  Jae Hak Yee ,  Feng Yao

Inventor： Guo Qiang Shen ,  Jae Hak Yee ,  Feng Yao

IPC: H01L23/31 ,  H01L21/56

CPC classification number: H01L23/49551 ,  H01L23/49503 ,  H01L24/29 ,  H01L24/32 ,  H01L24/45 ,  H01L24/48 ,  H01L2224/2919 ,  H01L2224/32245 ,  H01L2224/45014 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2224/83101 ,  H01L2924/00014 ,  H01L2924/0781 ,  H01L2924/14 ,  H01L2924/181 ,  H01L2924/0665 ,  H01L2924/00 ,  H01L2924/00012 ,  H01L2224/45015 ,  H01L2924/207

Abstract: A method of manufacture of an integrated circuit packaging system includes: forming a paddle having an indented planar surface intersecting an outwardly extending planar surface at an angle of approximately 135 degrees plus 25 degrees or minus 5 degrees; mounting an integrated circuit over the paddle; and forming an encapsulation over the integrated circuit and under the extension void free.

Abstract translation: 一种制造集成电路封装系统的方法包括：形成具有与大约135度加25度或者5度的角度相交的向外延伸的平坦表面的凹陷平面的桨叶; 在桨上安装集成电路; 并在集成电路上形成封装，并在扩展空间下形成封装。

公开(公告)号：US07678610B2

公开(公告)日：2010-03-16

申请号：US11260091

申请日：2005-10-28

Applicant: Chuen Khiang Wang ,  Hien Boon Tan ,  Anthony Yi Sheng Sun ,  Sin Nee Song ,  Steven Yu Feng Yao ,  Hua Hong Tan

Inventor： Chuen Khiang Wang ,  Hien Boon Tan ,  Anthony Yi Sheng Sun ,  Sin Nee Song ,  Steven Yu Feng Yao ,  Hua Hong Tan

IPC: H01L21/00

CPC classification number: H01L24/97 ,  H01L25/0652 ,  H01L25/0657 ,  H01L25/50 ,  H01L2224/32225 ,  H01L2224/48091 ,  H01L2224/48227 ,  H01L2224/4824 ,  H01L2224/73215 ,  H01L2224/97 ,  H01L2225/0651 ,  H01L2225/06555 ,  H01L2225/06572 ,  H01L2225/06582 ,  H01L2924/01006 ,  H01L2924/01029 ,  H01L2924/01032 ,  H01L2924/01033 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/07802 ,  H01L2924/10253 ,  H01L2924/14 ,  H01L2924/15311 ,  H01L2924/15331 ,  H01L2924/181 ,  H01L2924/18165 ,  H01L2924/19107 ,  H01L2224/85 ,  H01L2924/00014 ,  H01L2224/83 ,  H01L2924/00 ,  H01L2924/00012

Abstract: A semiconductor chip package and method of making the same. A first chip unit includes a first substrate and a first IC chip electrically connected to the first substrate. A second chip unit includes a second substrate and a second IC chip electronically connected to the second substrate. An adhesive material is provided on a surface of the first IC chip and the second chip unit is mounted onto the surface of the first chip unit including the adhesive material so that at least a portion of the second structure is encapsulated by the adhesive material, thereby providing some encapsulation in the same step as mounting. The first chip unit and the second chip unit may be separated by a spacer which may also provide an electrical connection.

Abstract translation: 一种半导体芯片封装及其制造方法。 第一芯片单元包括电连接到第一基板的第一基板和第一IC芯片。 第二芯片单元包括电子连接到第二基板的第二基板和第二IC芯片。 粘合材料设置在第一IC芯片的表面上，第二芯片单元安装在包括粘合材料的第一芯片单元的表面上，使得第二结构的至少一部分被粘合材料封装，从而 在与安装相同的步骤中提供一些封装。 第一芯片单元和第二芯片单元可以由也可以提供电连接的间隔件分开。

公开(公告)号：US20100015687A1

公开(公告)日：2010-01-21

申请号：US12553051

申请日：2009-09-02

Applicant: Feng Yao

Inventor： Feng Yao

IPC: C12N7/00 ,  C12N15/11

CPC classification number: C12N15/86 ,  A61K35/763 ,  C12N7/00 ,  C12N2710/16632 ,  C12N2710/16643 ,  C12N2830/003

Abstract: The present invention is directed oncolytic Herpes simplex-1 viruses whose replication is controlled using a tetracycline operator/repressor system. The invention also includes DNA sequences used in making the viruses and methods in which these viruses are used in the treatment of cancer patients with solid tumors.

Abstract translation: 本发明针对使用四环素操纵子/阻遏物系统进行复制的溶瘤性单纯疱疹病毒1型。 本发明还包括用于制备病毒的DNA序列和这些病毒用于治疗患有实体瘤的癌症患者的方法。

公开(公告)号：US06251640B1

公开(公告)日：2001-06-26

申请号：US09295336

申请日：1999-04-21

Applicant: Feng Yao

Inventor： Feng Yao

IPC: A61K4800

CPC classification number: C07K14/005 ,  A01K2217/05 ,  A61K48/00 ,  A61K2039/51 ,  C07K14/485 ,  C12N15/85 ,  C12N15/86 ,  C12N2710/16622 ,  C12N2710/16643 ,  C12N2830/00 ,  C12N2830/003

Abstract: The present invention is directed to DNA constructs suitable for gene expression in mammalian cells and which are characterized by the presence of a mammalian promoter under the control of a tet operator/repressor system. The DNA may be used as part of a system for expressing recombinant protein. In addition, the tet operator/repressor system can be used to engineer cis- and trans-destructive viruses which are capable of replicating in the presence of the tet repressor, but not in the absence of the repressor. These viruses can be used either directly in the treatment of patients with corresponding viral diseases, as vehicles for the delivery of nucleic acids that can serve as therapeutic agents and as part of vaccines designed to immunize people or animals against viral diseases.

Abstract translation: 本发明涉及适合于哺乳动物细胞中基因表达的DNA构建体，其特征在于在tet操纵子/阻遏物系统的控制下存在哺乳动物启动子。 DNA可以用作表达重组蛋白的系统的一部分。 此外，tet操作者/阻遏物系统可用于设计能够在tet阻遏物存在下复制的顺式和反式破坏性病毒，但不存在阻遏物。 这些病毒可以直接用于治疗患有相应病毒性疾病的患者，作为用于递送可用作治疗剂的核酸的载体，以及作为针对病毒性疾病免疫人或动物的疫苗的一部分。