摘要:
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
摘要:
Phospholipid-analogous compounds of the general formula (I) in which A is where R1 and R2 are, independently of one another, hydrogen, a saturated or unsaturated acyl or alkyl radical which can optionally be branched or/and substituted, where the total of the carbon atoms in the acyl and alkyl is 16 to 44 carbon atoms, s is an integer from 0 to 8, c is a radical of a primary or secondary alcohol of the formula RO—, where R is a saturated or unsaturated alkyl radical, mainly with cis double bond, of from 12 to 30 carbon atoms, n is an integer from 2 to 8, R3— a can be 1,2-dihydroxypropyl or b can be alkyl with 1 to 3 carbon atoms when z is >0 or c can be alkyl with 1 to 3 carbon atoms when n≠2, and z=0, m is 1 or 2, x is an integer from 0 to 8, y is 1 for z=1 to 5 or is 1 to 4 for z=1, z is an integer from 0 to 5, are novel and are suitable as liposome constituents, solubilizers and pharmaceuticals.
摘要:
The invention relates to indicator molecules for detecting the presence or concentration of an analyte in a medium, such as a liquid, and to methods for achieving such detection. More particularly, the invention relates to copolymer macromolecules containing relatively hydrophobic indicator component monomers, and hydrophilic monomers, such that the macromolecule is capable of use in an aqueous environment.
摘要:
In a transmitter 2A, after an output level of a modulated signal is regulated by a first gain regulator 5A, the signal is transmitted from a first antenna 8A without delay, and after the modulated signal is delayed by a delay unit 6A and an output level of the delay output is regulated by a second gain regulator 7A, this signal is transmitted from a second antenna 9A. Similarly, in a transmitter 2B, after an output level of a modulated signal is regulated by a first gain regulator 5B, the signal is transmitted from a first antenna 8B without delay, and after the modulated signal is delayed by a delay unit 6B and an output level of the delay output is regulated by a second gain regulator 7B, this signal is transmitted from a second antenna 9B. A receiver 3 receives the transmitted signals from the four antennas 8A, 8B, 9A and 9B via an antenna 10, and executes a demodulation process.
摘要:
An internal system and method for fixating an appendicular bone fracture in an individual. A plurality of fixating screws, each of which is adapted for placement in the bone at an anatomically favorable position, and at least one of which is adapted to provide interfragmentary reduction of the bone fracture are connectable to a rigid rod to provide bone fixation. A fracture positioning clamp for holding a reduced fracture in place until application of a fixation system.
摘要:
Apparatus for measuring a pattern in a surface of an object, comprising a plurality of pixel or sensor elements being responsive to a physical parameter of the object surface, and means for establishing an overall, segmented picture related to said pattern, and also comprising at least one diode functionally associated with each sensor element for contributing to one or more of the following functions: selectively addressing said sensor element activating said sensor element, and sensing of said physical parameter.
摘要:
The present application relates to lock assemblies that provide a secondary coupling point, utilizing an anti-rotation pin or extended tailpiece leg or other method, which rotationally couples the tailpiece to the cylinder plug, thereby preventing rotation of the tailpiece independently of the cylinder plug. Therefore, a tailpiece within a bolt cam or other actuator used to withdraw a bolt or unlock a lockset cannot be rotated after the tailpiece connector connecting the tailpiece to the cylinder plug has been forcibly removed, severed, or destroyed.
摘要:
The present disclosure provides a cucurbituril derivative-bonded solid substrate in which cucurbituril derivatives of Formula 1 are covalently bonded to a modified solid substrate of Formula 2. The cucurbituril derivative provides functional groups which can be used to link biomaterials to the substrate. Protein chips, gene chips, and sensors for biomaterial assays having the cucurbituril derivative-bonded solid substrate are also provided.
摘要:
The current invention is designed to improve the certainty of test-taker classifications in testing programs utilizing open-ended items. The current invention discloses methods to improve certainty in estimates of test-taker performance for all test-takers while using a minimum of scoring resources. The invention selectively allocates resources to scoring by ceasing to allocate scoring resources to test-takers whose performance has been determined with sufficient certainty, and by having an additional reader or readers score responses from test-takers whose scores are close to cutoff levels. The invention further increases precision of scores for test-takers near a cutoff by selectively allocating more reliable and accurate readers to score responses most likely to influence a test-taker's performance classification. Other scoring resources are also shown.