Compositions containing DMSO and Fructose 1,6-diphosphate
    22.
    发明授权
    Compositions containing DMSO and Fructose 1,6-diphosphate 失效
    含有DMSO和1,6-二磷酸果糖的组合物

    公开(公告)号:US5516526A

    公开(公告)日:1996-05-14

    申请号:US408840

    申请日:1995-03-22

    申请人: Jack da la Torre

    发明人: Jack da la Torre

    摘要: This invention relates to a method of protection from and treatment of neurological damage in mammals by administration of dimethylsulfoxide (DMSO) in combination with fructose 1,6-diphosphate (FDP). The effects of administration of the drugs together, either as two separate compositions or in combination, results in synergistic action that greatly improves protection from morbidity in animals (including humans) who have suffered injury to the brain.

    摘要翻译: 本发明涉及通过给予二甲基亚砜(DMSO)与1,6-二磷酸果糖(FDP)的组合来保护和治疗哺乳动物的神经损伤的方法。 将药物一起施用作为两种分开的组合物或组合的效果产生协同作用,其大大改善了对脑损伤的动物(包括人)的发病率的保护。

    Compositions containing forskolin and non-ionic surfactant
    23.
    发明授权
    Compositions containing forskolin and non-ionic surfactant 失效
    含有毛喉素和非离子表面活性剂的组合物

    公开(公告)号:US5457123A

    公开(公告)日:1995-10-10

    申请号:US252243

    申请日:1994-06-01

    IPC分类号: A61K20060101 A61K31/35

    CPC分类号: A61K31/35 Y10S514/936

    摘要: The invention relates to a process for the solubilization in a non-ionic surface-action agent of from between about 0.001 mg and about 1 mg of forskolin, to the pharmaceutical compositions based on such solubilized forskolin and to the use of these in the treatment of various diseases and disorders and maladies in mammals, including humans. Forskolin is 7-beta-acetoxy-8,13-epoxy-1-alpha,6-beta,9-alpha-trihydroxylabd-14-en-11-one.

    摘要翻译: 本发明涉及一种在非离子表面活性剂中溶解约0.001mg至约1mg的毛喉素的方法,涉及基于这种溶解的毛喉素的药物组合物及其用于治疗 哺乳动物,包括人类的各种疾病和病症和疾病。 福斯克林是7-β-乙酰氧基-8,13-环氧-1-α,6-β,9-α-三羟基萘-14-烯-11-酮。

    Pharmaceutical compositions and their use in the prophylaxis and/or
treatment of certain diseases
    28.
    发明授权
    Pharmaceutical compositions and their use in the prophylaxis and/or treatment of certain diseases 失效
    药物组合物及其在预防和/或治疗某些疾病中的用途

    公开(公告)号:US4296131A

    公开(公告)日:1981-10-20

    申请号:US65627

    申请日:1979-08-10

    摘要: The invention relates to a solvent vehicle for therapeutics comprising a dialkyl ester of adipic acid and, optionally, DMSO, which is particularly useful for therapeutic materials having a low solubility or being insoluble in water.The invention further relates to pharmaceutical compositions which are suitable for parenteral administration, especially by intramuscular injection, comprising a therapeutically active material dissolved in said solvent vehicle.Solvent vehicles containing di-n-butyl adipate and DMSO and, if desired, one or more adjuvants, are preferred.Particularly useful are pharmaceutical compositions for the prophylaxis and/or treatment of diseases caused by internal parasites, which can be administered by intramuscular injection. A preferred embodiment of the invention is an injectable composition against distomatosis (liver fluke disease) containing proportionally 12.5 g 4,6'-dichloro-4',6-dinitro-2,2'-methylenediphenol and 30 g of DMSO, completed with di-n-butyl adipate to 100 cm.sup.3.

    Solvent vehicle for the parenteral administration of therapeutics
    29.
    发明授权
    Solvent vehicle for the parenteral administration of therapeutics 失效
    用于胃肠外给药治疗剂的溶剂

    公开(公告)号:US4205089A

    公开(公告)日:1980-05-27

    申请号:US3968

    申请日:1979-01-16

    摘要: The invention relates to a solvent vehicle for therapeutics comprising a dialkyl ester of adipic acid and, optionally, DMSO, which is particularly useful for therapeutic materials having a low solubility or being insoluble in water. The invention further relates to pharmaceutical compositions which are suitable for parenteral administration, especially by intramuscular injection, comprising a therapeutically active material dissolved in said solvent vehicle. Solvent vehicles containing di-n-butyl adipate and DMSO and, if desired, one or more adjuvants, are preferred. Particularly useful are pharmaceutical compositions for the prophylaxis and/or treatment of diseases caused by internal parasites, which can be administered by intramuscular injection. A preferred embodiment of the invention is an injectable composition against distomatosis (liver fluke disease) containing proportionally 12.5 g 4,6'-dichloro-4',6-dinitro-2,2'-methylene-diphenol and 30 g of DMSO, completed with di-n-butyl adipate to 100 cm.sup.3.

    摘要翻译: 本发明涉及包含己二酸二烷基酯和任选的DMSO的治疗剂的溶剂载体,其特别可用于具有低溶解度或不溶于水的治疗物质。 本发明还涉及适合肠胃外给药,特别是通过肌内注射的药物组合物,其包含溶解在所述溶剂载体中的治疗活性物质。 含有己二酸二正丁酯和DMSO的溶剂载体,如果需要,优选一种或多种佐剂。 特别有用的是用于预防和/或治疗由内部寄生虫引起的疾病的药物组合物,其可以通过肌内注射施用。 本发明的一个优选实施方案是针对分离含有12.5g 4,6'-二氯-4',6-二硝基-2,2'-亚甲基 - 二苯酚和30g DMSO的针对脱水病(肝吸虫病)的可注射组合物,其完成 己二酸二正丁酯至100 cm3。

    Pesticidal Concentrates
    30.
    发明授权
    Pesticidal Concentrates 失效
    杀虫浓缩物

    公开(公告)号:US3894149A

    公开(公告)日:1975-07-08

    申请号:US37698073

    申请日:1973-07-06

    申请人: PROCTER & GAMBLE

    发明人: MAST ROY CLARK

    摘要: Concentrated liquid pesticidal compositions comprising well defined amounts of certain sparingly water-soluble pesticides, certain nonionic surfactants, and certain phase modifying cosurfactants.

    摘要翻译: 包含明确量的某些微水溶性农药,某些非离子表面活性剂和某些相改性助表面活性剂的浓缩液体杀虫组合物。